The DOI matches its Crossref record; 161 of the 161 references it cites were found in a registry or an index.
G-quadruplexes and helicases
Open accessAbstract
Guanine-rich DNA strands can fold in vitro into non-canonical DNA structures called G-quadruplexes. These structures may be very stable under physiological conditions. Evidence suggests that G-quadruplex structures may act as 'knots' within genomic DNA, and it has been hypothesized that proteins may have evolved to remove these structures. The first indication of how G-quadruplex structures could be unfolded enzymatically came in the late 1990s with reports that some well-known duplex DNA helicases resolved these structures in vitro. Since then, the number of studies reporting G-quadruplex DNA unfolding by helicase enzymes has rapidly increased. The present review aims to present a general overview of the helicase/G-quadruplex field.
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Cites
Quantitative visualization of DNA G-quadruplex structures in human cells
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Crystal structure of parallel quadruplexes from human telomeric DNA
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G-quadruplexes and their regulatory roles in biology
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Bochman, M. L., Paeschke, K., & Zakian, V. A. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3296 · Cited by 1,446
The Bloom's syndrome gene product is homologous to RecQ helicases
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Structure and Mechanism of Helicases and Nucleic Acid Translocases
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High-throughput sequencing of DNA G-quadruplex structures in the human genome
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DNA Quadruple Helices in Nanotechnology
Mergny, J.-L., & Sen, D. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00629 · Cited by 346
Self-citationG-quadruplex unwinding helicases and their function in vivo
Sauer, M., & Paeschke, K. (2017) · Biochemical Society Transactions · doi:10.1042/bst20170097 · Cited by 179
Hu, M.-H., Wang, Y.-Q., Yu, Z.-Y., Hu, L.-N., Ou, T.-M., Chen, S.-B., Huang, Z.-S., & Tan, J.-H. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.7b01697 · Cited by 101
Crosstalk between G-quadruplex and ROS
Wu, S., Jiang, L., Lei, L., Fu, C., Huang, J., Hu, Y., Dong, Y., Chen, J., & Zeng, Q. (2023) · Cell Death & Disease · doi:10.1038/s41419-023-05562-0 · Cited by 69
“The unfolding and folding of G4s during replication or transcription are mainly catalyzed by helicases [54, 55] including DNA G4 helicases such as Pif1, ATRX, RecQ, FANCJ, BLM and WRN [54], and RNA G4 helicases such as DHX9, DHX36, and the DDX5/ DDX17/Dbp2 subfamily [56] (Fig.”
Background
Metadata
- Authors
- Mendoza, O., Bourdoncle, A., Boulé, J.-B., Brosh, R. M., & Mergny, J.-L.
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2016-02-15
- Volume
- 44
- Issue
- 5
- Pages
- 1989-2006
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- OpenAlex
- W2275411324
- Cited by
- 458
- References
- 161
- FWCI
- 21.67
- Type
- journal article
- Language
- en
- Open access
- gold
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