The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Structure and Mechanism of Helicases and Nucleic Acid Translocases
Abstract
Helicases and translocases are a ubiquitous, highly diverse group of proteins that perform an extraordinary variety of functions in cells. Consequently, this review sets out to define a nomenclature for these enzymes based on current knowledge of sequence, structure, and mechanism. Using previous definitions of helicase families as a basis, we delineate six superfamilies of enzymes, with examples of crystal structures where available, and discuss these structures in the context of biochemical data to outline our present understanding of helicase and translocase activity. As a result, each superfamily is subdivided, where appropriate, on the basis of mechanistic understanding, which we hope will provide a framework for classification of new superfamily members as they are discovered and characterized.
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Cites
The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants
Scheffzek, K., Ahmadian, M. R., Kabsch, W., Wiesmüller, L., Lautwein, A., Schmitz, F., & Wittinghofer, A. (1997) · Science · doi:10.1126/science.277.5324.333 · Cited by 1,543
Crystal structure of a DExx box DNA helicase
Subramanya, H. S., Bird, L. E., Brannigan, J. A., & Wigley, D. B. (1996) · Nature · doi:10.1038/384379a0 · Cited by 433
Self-citationDillingham, M. S., Soultanas, P., & Wigley, D. B. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.16.3310 · Cited by 94
Self-citation
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Clapier, C. R., Iwasa, J., Cairns, B. R., & Peterson, C. L. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.26 · Cited by 1,305
The 3D Genome as Moderator of Chromosomal Communication
Dekker, J., & Mirny, L. (2016) · Cell · doi:10.1016/j.cell.2016.02.007 · Cited by 937
Double-Stranded RNA Sensors and Modulators in Innate Immunity
Hur, S. (2019) · Annual Review of Immunology · doi:10.1146/annurev-immunol-042718-041356 · Cited by 420
Fan, L., Fuss, J. O., Cheng, Q. J., Arvai, A. S., Hammel, M., Roberts, V. A., Cooper, P. K., & Tainer, J. A. (2008) · Cell · doi:10.1016/j.cell.2008.04.030 · Cited by 369
Mechanisms for initiating cellular DNA replication
Bleichert, F., Botchan, M. R., & Berger, J. M. (2017) · Science · doi:10.1126/science.aah6317 · Cited by 220
Metadata
- Authors
- Singleton, M. R., Dillingham, M. S., & Wigley, D. B.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 2007-06-07
- Volume
- 76
- Issue
- 1
- Pages
- 23-50
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2105439835
- Cited by
- 1,274
- References
- 3
- FWCI
- 3.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Singleton, M. R., Dillingham, M. S., & Wigley, D. B. (2007). Structure and Mechanism of Helicases and Nucleic Acid Translocases. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.biochem.76.052305.115300
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