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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Open accessAbstract
Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and biology of these tumors, but this has not translated into significantly improved outcomes for patients. In this consensus review from the Society for Neuro-Oncology (SNO) and the European Association of Neuro-Oncology (EANO), the current management of isocitrate dehydrogenase wildtype (IDHwt) glioblastomas will be discussed. In addition, novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies, and viral therapies will be reviewed, as well as the current challenges and future directions for research.
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Mutant IDH1 and thrombosis in gliomas
Unruh, D. J., Schwarze, S. R., Khoury, L., Thomas, C., Wu, M., Chen, L., Chen, R., Liu, Y., Schwartz, M. A., Amidei, C., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1620-7 · Cited by 173
Self-citationWen, P. Y., Touat, M., Alexander, B. M., Mellinghoff, I. K., Ramkissoon, S. H., McCluskey, C. S., Pelton, K., Haidar, S., Basu, S. S., Gaffey, S. C., et al. (2019) · Journal of Clinical Oncology · doi:10.1200/jco.18.01207 · Cited by 173
Self-citationGrossman, S. A., Ye, X., Chamberlain, M. C., Mikkelsen, T., Batchelor, T. T., Desideri, S., Piantadosi, S., Fisher, J. D., & Fine, H. A. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2008.21.6895 · Cited by 170
Self-citationMedical management of brain tumors and the sequelae of treatment
Schiff, D., Lee, E. Q., Nayak, L., Norden, A. D., Reardon, D. A., & Wen, P. Y. (2014) · Neuro-Oncology · doi:10.1093/neuonc/nou304 · Cited by 170
Self-citationCloughesy, T. F., Landolfi, J. C., Vogelbaum, M. A., Ostertag, D. G., Elder, J. B., Bloomfield, S. M., Carter, B. S., Chen, C. C., Kalkanis, S. N., Kesari, S., et al. (2018) · Neuro-Oncology · doi:10.1093/neuonc/noy075 · Cited by 170
Self-citationWhat do we know about IDH1/2 mutations so far, and how do we use it?
Horbinski, C. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1106-9 · Cited by 169
Self-citationDanilova, L., Anagnostou, V., Caushi, J. X., Sidhom, J.-W., Guo, H., Chan, H. Y., Suri, P., Tam, A. J., Zhang, J., Asmar, M. E., et al. (2018) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0129 · Cited by 169
Wu, A., Trinh, V. T., Suki, D., Graham, S., Forman, A. D., Weinberg, J. S., McCutcheon, I. E., Prabhu, S. S., Heimberger, A. B., Sawaya, R. A., et al. (2013) · Journal of neurosurgery · doi:10.3171/2012.12.jns111970 · Cited by 166
Philips, A., Henshaw, D. L., Lamburn, G., & O’Carroll, M. J. (2018) · Journal of Environmental and Public Health · doi:10.1155/2018/7910754 · Cited by 165
Wick, W., Gorlia, T., Bady, P., Platten, M., van den Bent, M. J., TAPHOORN, M. J. B., Steuve, J., Brandes, A. A., Hamou, M., Wick, A., et al. (2016) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-15-3153 · Cited by 164
Self-citationComplications of therapy for venous thromboembolic disease in patients with brain tumors
Levin, J. M., Schiff, D., Loeffler, J. S., Fine, H. A., Black, P. M., & Wen, P. Y. (1993) · Neurology · doi:10.1212/wnl.43.6.1111 · Cited by 161
Self-citationKickingereder, P., Wiestler, B., Sahm, F., Heiland, S., Roethke, M. C., Schlemmer, H.-P., Wick, W., Bendszus, M., & Radbruch, A. (2014) · Radiology · doi:10.1148/radiol.14132740 · Cited by 158
Self-citationBlumenthal, D. T., Gorlia, T., Gilbert, M. R., Kim, M. M., Nabors, B., Mason, W. P., Hegi, M. E., Zhang, P., Golfinopoulos, V., Perry, J., et al. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox025 · Cited by 158
Self-citationChinnaiyan, P., Won, M., Wen, P. Y., Rojiani, A. M., Werner‐Wasik, M., Shih, H. A., Ashby, L. S., Yu, H.-H. M., Stieber, V. W., Malone, S. C., et al. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox209 · Cited by 158
Self-citationJonsson, P., Lin, A. L., Young, R. J., DiStefano, N. M., Hyman, D. M., Li, B. T., Berger, M. F., Zehir, A., Ladanyi, M., Solit, D. B., et al. (2019) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-0032 · Cited by 156
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Jenkinson, M. D., Barone, D. G., Bryant, A., Vale, L. D., Bulbeck, H., Lawrie, T. A., Hart, M. G., & Watts, C. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012788.pub2 · Cited by 155
Hegi, M. E., Genbrugge, E., Gorlia, T., Stupp, R., Gilbert, M. R., Chinot, O. L., Nabors, B., Jones, G., Criekinge, W. V., Straub, J., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-3181 · Cited by 155
Self-citationThe clinical trials landscape for glioblastoma: is it adequate to develop new treatments?
Vanderbeek, A. M., Rahman, R. M., Fell, G. G., Ventz, S., Chen, T., Redd, R. A., Parmigiani, G., Cloughesy, T. F., Wen, P. Y., Trippa, L., et al. (2018) · Neuro-Oncology · doi:10.1093/neuonc/noy027 · Cited by 150
Self-citationManagement of Venous Thromboembolism in Patients With Primary and Metastatic Brain Tumors
Gerber, D. E., Grossman, S. A., & Streiff, M. B. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.04.6656 · Cited by 149
Review of cranial radiotherapy-induced vasculopathy
Murphy, E. S., Xie, H., Merchant, T. E., Yu, J. S., Chao, S. T., & Suh, J. H. (2015) · Journal of Neuro-Oncology · doi:10.1007/s11060-015-1732-2 · Cited by 149
Sadeghi, N., D’Haene, N., Decaestecker, C., Levivier, M., Metens, T., Maris, C., Wikler, D., Balériaux, D., Salmon, I. J., & Goldman, S. (2007) · American Journal of Neuroradiology · doi:10.3174/ajnr.a0851 · Cited by 148
Clinical investigation of CAR T cells for solid tumors: Lessons learned and future directions
Bagley, S. J., & O’Rourke, D. M. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2019.107419 · Cited by 147
Emerging intersections between neuroscience and glioma biology
Jung, E., Alfonso, J., Osswald, M., Monyer, H., Wick, W., & Winkler, F. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0540-y · Cited by 146
Self-citationWick, W., Dettmer, S., Berberich, A., Keßler, T., Karapanagiotou‐Schenkel, I., Wick, A., Winkler, F., Pfaff, E., Brors, B., Debus, J., et al. (2018) · Neuro-Oncology · doi:10.1093/neuonc/noy161 · Cited by 145
Self-citationFGFR-TACC gene fusions in human glioma
Lasorella, A., Sanson, M., & Iavarone, A. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now240 · Cited by 144
Self-citationAkhavan, D., Pourzia, A. L., Nourian, A. A., Williams, K. J., Nathanson, D. A., Babić, I., Villa, G. R., Tanaka, K., Nael, A., Yang, H., et al. (2013) · Cancer Discovery · doi:10.1158/2159-8290.cd-12-0502 · Cited by 143
Self-citationPINK1 Is a Negative Regulator of Growth and the Warburg Effect in Glioblastoma
Agnihotri, S., Golbourn, B. J., Huang, X., Remke, M., Younger, S. H., Cairns, R. A., Chalil, A., Smith, C. A., Krumholtz, S.-L., Mackenzie, D., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-3079 · Cited by 142
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Venneti, S., & Thompson, C. B. (2017) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-012615-044329 · Cited by 139
van den Bent, M. J., Gan, H. K., Lassman, A. B., Kumthekar, P., Merrell, R. T., Butowski, N. A., Lwin, Z., Mikkelsen, T., Nabors, B., Papadopoulos, K. P., et al. (2017) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-017-3451-1 · Cited by 139
Self-citationBoele, F. W., Douw, L., de Groot, M., van Thuijl, H. F., Cleijne, W., Heimans, J. J., TAPHOORN, M. J. B., Reijneveld, J. C., & Klein, M. (2013) · Neuro-Oncology · doi:10.1093/neuonc/not102 · Cited by 138
Self-citationKorshunov, A., Chávez, L., Sharma, T., Ryzhova, M. V., Schrimpf, D., Stichel, D., Capper, D., Sturm, D., Kool, M., Habel, A., et al. (2017) · Brain Pathology · doi:10.1111/bpa.12566 · Cited by 136
Wick, W., Fricke, H., Junge, K., Kobyakov, G., Martens, T., Heese, O., Wiestler, B., Schliesser, M. G., von Deimling, A., Pichler, J., et al. (2014) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-0951-t · Cited by 135
Self-citationExercise Behavior, Functional Capacity, and Survival in Adults With Malignant Recurrent Glioma
Ruden, E. A., Reardon, D. A., Sykes, A. D., Herndon, J. E., Hornsby, W., West, M. J., Fels, D. R., Desjardins, A., Vredenburgh, J. J., Waner, E., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.34.9852 · Cited by 128
Self-citationGupta, S. K., Kizilbash, S. H., Carlson, B. L., Mladek, A. C., Boakye‐Agyeman, F., Bakken, K. K., Pokorny, J. L., Schroeder, M. A., Decker, P. A., Cen, L., et al. (2015) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djv369 · Cited by 128
Self-citationNRG brain tumor specialists consensus guidelines for glioblastoma contouring
Kruser, T. J., Bosch, W. R., Badiyan, S. N., Bovi, J. A., Ghia, A. J., Kim, M. M., Solanki, A. A., Sachdev, S., Tsien, C. I., Wang, T. J. C., et al. (2019) · Journal of Neuro-Oncology · doi:10.1007/s11060-019-03152-9 · Cited by 126
Self-citationDraaisma, K., Chatzipli, A., TAPHOORN, M. J. B., Kerkhof, M., Weyerbrock, A., Sanson, M., Hoeben, A., Lukacova, S., Lombardi, G., Leenstra, S., et al. (2019) · Journal of Clinical Oncology · doi:10.1200/jco.19.00367 · Cited by 125
Self-citationHu, L., Eschbacher, J. M., Dueck, A. C., Heiserman, J. E., Liu, S., Karis, J. P., Smith, K. A., Shapiro, W. R., Pinnaduwage, D. S., Coons, S. W., et al. (2011) · American Journal of Neuroradiology · doi:10.3174/ajnr.a2743 · Cited by 123
Antiepileptic drugs as prophylaxis for post-craniotomy seizures
Weston, J., Greenhalgh, J., & Marson, A. G. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007286.pub3 · Cited by 121
Wen, P. Y., Drappatz, J., de Groot, J., Prados, M. D., Reardon, D. A., Schiff, D., Chamberlain, M. C., Mikkelsen, T., Desjardins, A., Holland, J. S., et al. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox154 · Cited by 121
Self-citationIntracranial hemorrhage with direct oral anticoagulants in patients with brain tumors
Carney, B. J., Uhlmann, E. J., Puligandla, M., Mantia, C. M., Weber, G. M., Neuberg, D. S., & Zwicker, J. I. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14336 · Cited by 119
Clarke, J. L., Ennis, M. M., Yung, W. K. A., Chang, S., Wen, P. Y., Cloughesy, T. F., DeAngelis, L. M., Robins, H. I., Lieberman, F. S., Fine, H. A., et al. (2011) · Neuro-Oncology · doi:10.1093/neuonc/nor110 · Cited by 117
Self-citationEffectiveness of antiepileptic prophylaxis used with supratentorial craniotomies: a meta-analysis
Jos, M. A. K., Onno, P. M. T., Alphons, G. H. K., Marcel, J. H. M. H., & Emiel, A. M. B. (1996) · Seizure · doi:10.1016/s1059-1311(96)80023-9 · Cited by 114
Wesseling, P., van der Laak, J. A. W. M., de Leeuw, H., Ruiter, D. J., & Burger, P. C. (1994) · Journal of neurosurgery · doi:10.3171/jns.1994.81.6.0902 · Cited by 113
Frequency of BRAF V600E mutations in 969 central nervous system neoplasms
Behling, F., Barrantes‐Freer, A., Skardelly, M., Nieser, M., Christians, A., Stockhammer, F., Rohde, V., Tatagiba, M. S., Hartmann, C. J., Stadelmann, C., et al. (2016) · Diagnostic Pathology · doi:10.1186/s13000-016-0506-2 · Cited by 112
Epidemiology of Intracranial Gliomas
Ostrom, Q. T., Gittleman, H. R., Stetson, L. C., Virk, S. M., & Barnholtz‐Sloan, J. S. (2017) · Progress in neurological surgery · doi:10.1159/000464374 · Cited by 112
Self-citationReardon, D. A., Wen, P. Y., & Mellinghoff, I. K. (2014) · Neuro-Oncology · doi:10.1093/neuonc/nou232 · Cited by 111
Self-citationReardon, D. A., Lassman, A. B., van den Bent, M. J., Kumthekar, P., Merrell, R. T., Scott, A. M., Fichtel, L., Sulman, E. P., Gomez, E. J., Fischer, J. S., et al. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now257 · Cited by 110
Self-citationMantia, C. M., Uhlmann, E. J., Puligandla, M., Weber, G. M., Neuberg, D. S., & Zwicker, J. I. (2017) · Blood · doi:10.1182/blood-2017-02-767285 · Cited by 109
Balañá, C., Salgado, M. Á. V., Sepúlveda-Sánchez, J. M., Mesía, C., Barco, S. D., Pineda, E., Muñoz-Langa, J., Estival, A., Peñas, R. D. L., Fuster, J., et al. (2020) · Neuro-Oncology · doi:10.1093/neuonc/noaa107 · Cited by 109
Wick, W., Chinot, O. L., Bendszus, M., Mason, W. P., Henriksson, R., Saran, F. H., Nishikawa, R., Révil, C., Kerloëguen, Y., & Cloughesy, T. F. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now091 · Cited by 104
Self-citationSleep-wake disturbance in patients with brain tumors
Armstrong, T. S., Shade, M. Y., Breton, G., Gilbert, M. R., Mahajan, A., Scheurer, M. E., Vera, E. M., & Berger, A. M. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now119 · Cited by 102
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Wu, W., Lamborn, K. R., Buckner, J. C., Novotny, P. J., Chang, S., O'Fallon, J. R., Jaeckle, K. A., & Prados, M. D. (2009) · Neuro-Oncology · doi:10.1093/neuonc/nop019 · Cited by 101
Self-citationRooney, A. G., McNamara, S., Mackinnon, M., Fraser, M., Rampling, R., Carson, A. J., & Grant, R. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.34.8466 · Cited by 100
Wen, P. Y., Cloughesy, T. F., Olivero, A. G., Morrissey, K. M., Wilson, T. R., Lu, X., Mueller, L. U., Coimbra, A. F., Ellingson, B. M., Gerstner, E. R., et al. (2020) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-2808 · Cited by 100
Self-citationHegi, M. E., & Stupp, R. (2015) · Neuro-Oncology · doi:10.1093/neuonc/nov198 · Cited by 99
Self-citationMai, W. X., Gosa, L., Daniëls, V. W., Ta, L. H., Tsang, J., Higgins, B., Gilmore, W. B., Bayley, N. A., Harati, M. D., Lee, J. T., et al. (2017) · Nature Medicine · doi:10.1038/nm.4418 · Cited by 97
Self-citationEllingson, B. M., Abrey, L. E., Nelson, S. J., Kaufmann, T. J., Garcia, J., Chinot, O. L., Saran, F. H., Nishikawa, R., Henriksson, R., Mason, W. P., et al. (2018) · Neuro-Oncology · doi:10.1093/neuonc/noy053 · Cited by 97
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Norden, A. D., Bartolomeo, J., Tanaka, S., Drappatz, J., Ciampa, A. S., Doherty, L. M., LaFrankie, D. C., Ruland, S. F., Lee, E. Q., Beroukhim, R., et al. (2011) · Journal of Neuro-Oncology · doi:10.1007/s11060-011-0642-1 · Cited by 94
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Armstrong, T. S., & Gilbert, M. R. (2012) · Neuro-Oncology · doi:10.1093/neuonc/nos210 · Cited by 92
Self-citationWirsching, H., Tabatabai, G., Roelcke, U., Hottinger, A. F., Jörger, F., Schmid, A., Plaßwilm, L., Schrimpf, D., Mancao, C., Capper, D., et al. (2018) · Annals of Oncology · doi:10.1093/annonc/mdy120 · Cited by 91
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Self-citationBrandes, A. A., Finocchiaro, G., Zagonel, V., Reni, M., Caserta, C., Fabi, A., Clavarezza, M., Maiello, E., Eoli, M., Lombardi, G., et al. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now035 · Cited by 82
Gupta, S. K., Smith, E. J., Mladek, A. C., Tian, S., Decker, P. A., Kizilbash, S. H., Kitange, G. J., & Sarkaria, J. N. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2018.00670 · Cited by 82
Alexander, B. M., Trippa, L., Gaffey, S. C., Arrillaga‐Romany, I., Lee, E. Q., Rinne, M. L., Ahluwalia, M. S., Colman, H., Fell, G. G., Galanis, E., et al. (2019) · JCO Precision Oncology · doi:10.1200/po.18.00071 · Cited by 82
Self-citationGupta, S. K., Mladek, A. C., Carlson, B. L., Boakye‐Agyeman, F., Bakken, K. K., Kizilbash, S. H., Schroeder, M. A., Reid, J. M., & Sarkaria, J. N. (2014) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-13-3446 · Cited by 81
Gehring, K., TAPHOORN, M. J. B., Sitskoorn, M. M., & Aaronson, N. K. (2015) · Neuro-Oncology Practice · doi:10.1093/nop/npu035 · Cited by 81
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Ventz, S., Lai, A., Cloughesy, T. F., Wen, P. Y., Trippa, L., & Alexander, B. M. (2019) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-19-0820 · Cited by 80
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Self-citationCloughesy, T. F., Brenner, A. J., de Groot, J., Butowski, N. A., Zach, L., Campian, J. L., Ellingson, B. M., Freedman, L. S., Cohen, Y. C., Lowenton‐Spier, N., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz232 · Cited by 75
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Agnihotri, S., Mansouri, S., Burrell, K. E., Li, M., Mamatjan, Y., Liu, J., Nejad, R., Kumar, S., Jalali, S., Singh, S. K., et al. (2018) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-18-1854 · Cited by 73
Self-citationLabrèche, K., Kinnersley, B., Berzero, G., Stefano, A. L. D., Rahimian, A., Detrait, I., Marie, Y., Grenier‐Boley, B., Hoang‐Xuan, K., Delattre, J., et al. (2018) · Acta Neuropathologica · doi:10.1007/s00401-018-1825-z · Cited by 70
Self-citationHorbinski, C., Ligon, K. L., Brastianos, P. K., Huse, J. T., Venere, M., Chang, S. M., Buckner, J. C., Cloughesy, T. F., Jenkins, R. B., Giannini, C., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz119 · Cited by 70
Self-citationCloughesy, T. F., Drappatz, J., de Groot, J., Prados, M. D., Reardon, D. A., Schiff, D., Chamberlain, M. C., Mikkelsen, T., Desjardins, A., Ping, J., et al. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox151 · Cited by 70
Self-citationScoccianti, S., Francolini, G., Carta, G. A., Greto, D., Detti, B., Simontacchi, G., Visani, L., Baki, M., Poggesi, L., Bonomo, P., et al. (2018) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2018.03.024 · Cited by 69
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Self-citationEllingson, B. M., Gerstner, E. R., Smits, M., Huang, R. Y., Colen, R. R., Abrey, L. E., Aftab, D. T., Schwab, G. M., Hessel, C., Harris, R. J., et al. (2017) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-16-2844 · Cited by 67
Self-citationDeWitt, J. C., Jordan, J. T., Frosch, M. P., Samore, W. R., Iafrate, A. J., Louis, D. N., & Lennerz, J. K. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox120 · Cited by 67
Shi, W., Bryan, M. S., Gilbert, M. R., Mehta, M. P., Blumenthal, D. T., Brown, P. D., Valeinis, E., Hopkins, K., Souhami, L., Andrews, D. W., et al. (2017) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2017.08.038 · Cited by 67
Self-citationSuh, C. H., Kim, H. S., Jung, S. C., Park, J. E., Choi, C. G., & Kim, S. J. (2019) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.26602 · Cited by 66
Eigenbrod, S., Trabold, R., Brucker, D., Erös, C., Egensperger, R., la Fougère, C. J., Göbel, W., Rühm, A., Kretzschmar, H. A., Tonn, J. C., et al. (2014) · Acta Neurochirurgica · doi:10.1007/s00701-014-2073-1 · Cited by 65
Self-citationNitrosoureas in the Management of Malignant Gliomas
Brandes, A. A., Bartolotti, M., Tosoni, A., & Franceschi, E. (2016) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-015-0611-8 · Cited by 63
Lee, E. Q., Muzikansky, A., Drappatz, J., Kesari, S., Wong, E. T., Fadul, C. E., Reardon, D. A., Norden, A. D., Nayak, L., Rinne, M. L., et al. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now007 · Cited by 61
Self-citationAntiepileptic drugs as prophylaxis for post-craniotomy seizures
Pulman, J., Greenhalgh, J., & Marson, A. G. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007286.pub2 · Cited by 59
Glioblastoma: Radiation treatment margins, how small is large enough?
Wernicke, A. G., Smith, A. W., Taube, S., & Mehta, M. P. (2015) · Practical Radiation Oncology · doi:10.1016/j.prro.2015.12.002 · Cited by 56
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Self-citationHaider, A. S., van den Bent, M. J., Wen, P. Y., Vogelbaum, M. A., Chang, S. M., Canoll, P., Horbinski, C., & Huse, J. T. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz233 · Cited by 53
Self-citationIntraoperative imaging technology to maximise extent of resection for glioma
Jenkinson, M. D., Barone, D. G., Hart, M. G., Bryant, A., Lawrie, T. A., & Watts, C. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012788 · Cited by 52
Clinical Relevance of Steroid Use in Neuro-Oncology
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Self-citationGenetic Syndromes Associated with Central Nervous System Tumors
Vijapura, C. A., Aldin, E. S., Capizzano, A. A., Policeni, B. A., Satō, Y., & Moritani, T. (2016) · Radiographics · doi:10.1148/rg.2017160057 · Cited by 50
Improving survival in molecularly selected glioblastoma
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Self-citationTodo, T. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.014 · Cited by 45
Lee, E. Q., Weller, M., Sul, J., Bagley, S. J., Sahebjam, S., van den Bent, M. J., Ahluwalia, M. S., Campian, J. L., Galanis, E., Gilbert, M. R., et al. (2020) · Neuro-Oncology · doi:10.1093/neuonc/noaa015 · Cited by 45
Self-citationHeffron, T. P. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox179 · Cited by 43
Brenner, A. J., Peters, K. B., Vredenburgh, J. J., Bokstein, F., Blumenthal, D. T., Yust‐Katz, S., Peretz, I., Oberman, B., Freedman, L. S., Ellingson, B. M., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz231 · Cited by 39
Self-citationLetter: When Less is More: Dexamethasone Dosing for Brain Tumors
Lim-Fat, M. J., Bi, W. L., Lo, J., Lee, E. Q., Ahluwalia, M. S., Batchelor, T. T., Chang, S. M., Chiocca, E. A., Chukwueke, U. N., Cloughesy, T. F., et al. (2019) · Neurosurgery · doi:10.1093/neuros/nyz186 · Cited by 33
Self-citationFamilial syndromes associated with intracranial tumours: a review
Ranger, A. M., Patel, Y. K., Chaudhary, N., & Anantha, R. V. (2013) · Child s Nervous System · doi:10.1007/s00381-013-2309-z · Cited by 32
Straube, C., Kessel, K. A., Zimmer, C., Schmidt‐Graf, F., Schlegel, J., Gempt, J., Meyer, B., & Combs, S. E. (2019) · Current Treatment Options in Oncology · doi:10.1007/s11864-019-0673-y · Cited by 31
Imaging of Central Nervous System Tumors Based on the 2016 World Health Organization Classification
Ly, I., Wen, P. Y., & Huang, R. Y. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.08.004 · Cited by 30
Self-citationImmunotherapy for glioblastoma: going viral
Iorgulescu, J. B., Reardon, D. A., Chiocca, E. A., & Wu, C. J. (2018) · Nature Medicine · doi:10.1038/s41591-018-0142-3 · Cited by 29
Self-citationCorticosteroids for peritumoral edema: time to overcome our addiction?
Lee, E. Q., & Wen, P. Y. (2016) · Neuro-Oncology · doi:10.1093/neuonc/now167 · Cited by 27
Self-citationHovey, E. J., Field, K. M., Rosenthal, M. A., Barnes, E. H., Cher, L., Nowak, A. K., Wheeler, H., Sawkins, K., Livingstone, A., Phal, P. M., et al. (2017) · Neuro-Oncology Practice · doi:10.1093/nop/npw025 · Cited by 26
It Is Time to Include Patients With Brain Tumors in Phase I Trials in Oncology
Wen, P. Y., Schiff, D., Cloughesy, T. F., Reardon, D. A., Batchelor, T. T., Chabner, B. A., Flaherty, K. T., de Groot, J., Gilbert, M. R., Galanis, E., et al. (2011) · Journal of Clinical Oncology · doi:10.1200/jco.2011.36.6328 · Cited by 25
Self-citationLassman, A. B., Pugh, S. L., Wang, T., Aldape, K., Gan, H. K., Preusser, M., Vogelbaum, M. A., Sulman, E. P., Won, M., Zhang, P., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.064 · Cited by 25
Self-citationMR Perfusion and MR Spectroscopy of Brain Neoplasms
Gharzeddine, K., Hatzoglou, V., Holodny, A. I., & Young, R. J. (2019) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2019.07.008 · Cited by 23
Wen, P. Y., Stein, A., van den Bent, M. J., Grève, J. D., Dietrich, S., Vos, F. D., von Bubnoff, N. C. C., van Linde, M., Lai, A., Prager, G. W., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.073 · Cited by 22
Self-citationLu, X., Xu, W., Wei, Y., Li, T., Gao, L., Fu, X., Yao, Y., & Wang, L. (2019) · Neurological Sciences · doi:10.1007/s10072-019-03732-7 · Cited by 21
Philips, A., Henshaw, D. L., Lamburn, G., & O’Carroll, M. J. (2018) · Journal of Environmental and Public Health · doi:10.1155/2018/2170208 · Cited by 19
Lee, B., Park, J. E., Bjørnerud, A., Kim, J. H., Lee, J. Y., & Kim, H. S. (2018) · American Journal of Neuroradiology · doi:10.3174/ajnr.a5732 · Cited by 19
Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors
Gounder, M. M., Nayak, L., Sahebjam, S., Muzikansky, A., Sanchez, A. J., Desideri, S., Ye, X., Ivy, S. P., Nabors, B., Prados, M. D., et al. (2015) · Journal of Clinical Oncology · doi:10.1200/jco.2015.61.1525 · Cited by 18
Self-citationTsien, C. I., Pugh, S. L., Dicker, A. P., Raizer, J. J., Matuszak, M. M., Lallana, E. C., Huang, J., Algan, Ö., Taylor, N., Portelance, L., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.075 · Cited by 15
Self-citationAssociations of anticoagulant use with outcome in newly diagnosed glioblastoma
Rhun, É. L., Genbrugge, E., Stupp, R., Chinot, O. L., Nabors, B., Cloughesy, T. F., Reardon, D. A., Wick, W., Gorlia, T., & Weller, M. (2018) · European Journal of Cancer · doi:10.1016/j.ejca.2018.06.029 · Cited by 14
Self-citationThrombotic Complications in Gliomas
Czap, A. L., Becker, A., & Wen, P. Y. (2019) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0039-1687892 · Cited by 14
Self-citationTargeting DNA repair in gliomas
Beckta, J. M., Bindra, R. S., & Chalmers, A. J. (2019) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000760 · Cited by 13
Self-citationWeller, M. (2018) · Cancer · doi:10.1002/cncr.31244 · Cited by 12
Self-citationThe role of amino-acid PET in the light of the new WHO classification 2016 for brain tumors
Suchorska, B., Albert, N. L., Bauer, E. K., Tonn, J., & Galldiks, N. (2018) · The Quarterly Journal of Nuclear Medicine and Molecular Imaging · doi:10.23736/s1824-4785.18.03090-x · Cited by 10
Self-citationLassman, A. B., Sepúlveda-Sánchez, J. M., Cloughesy, T. F., Gil-Gil, J., Puduvalli, V. K., Raizer, J. J., Vos, F. D., Wen, P. Y., Butowski, N. A., Clément, P. M., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.076 · Cited by 8
Self-citationAssociations of anticoagulant use with outcome in newly diagnosed glioblastoma.
Rhun, É. L., Genbrugge, E., Stupp, R., Chinot, O. L., Nabors, B., Cloughesy, T. F., Reardon, D. A., Wick, W., Gorlia, T., & Weller, M. (2018) · Journal of Clinical Oncology · doi:10.1200/jco.2018.36.15_suppl.e14070 · Cited by 5
Self-citationWelch, M. R., Segall, L., Hillyer, G. C., IWAMOTO, F. M., Kreisl, T. N., Otap, D., & Lassman, A. B. (2017) · Neuro-Oncology · doi:10.1093/neuonc/nox168.289 · Cited by 3
Self-citationTesileanu, C. M. S., Koekkoek, J. A. F., Dirven, L., Dubbink, H. J., Kros, J. M., van Duinen, S. G., Smits, M., French, P. J., TAPHOORN, M. J. B., & van den Bent, M. J. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz126.067 · Cited by 3
Self-citationWeller, M., Reardon, D. A., Brandes, A. A., Sampson, J. H., Mulholland, P. J., Wick, A., Baehring, J. M., Ahluwalia, M. S., Roth, P., Bähr, O., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.045 · Cited by 3
Self-citationPL3.5 Efficacy and safety of selinexor in recurrent glioblastoma
Lassman, A. B., Wen, P. Y., van den Bent, M. J., Plotkin, S. R., Walenkamp, A. M. E., Green, A., Huang, X., Rodriguez-Lopez, K., Kauffman, M. G., Shacham, S., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz126.008 · Cited by 2
Self-citationACTR-34. SINGLE AGENT ONC201 IN PREVIOUSLY-TREATED, PROGRESSIVE ADULT H3 K27M-MUTANT GLIOMA
Arrillaga‐Romany, I., Kurz, S. C., Sumrall, A. L., Butowski, N. A., Harrison, R. A., DeGroot, J. F., Chi, A. S., Sulman, E. P., Shonka, N., Umemura, Y., et al. (2019) · Neuro-Oncology · doi:10.1093/neuonc/noz175.077 · Cited by 1
Self-citationWen, P. (2019) · VUBIR (Vrije Universiteit Brussel) · Cited by 1
Self-citation
Flagged first, then by citations
4 of the 334 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- World Health Organization., 2016, Histological Classification of Tumors of The Central Nervous System
- NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), 2019, Central Nervus System Cancers
- Chang, 2019, Neoplasms of the central nervous system., 1568
Cited by
Sorted by citations
EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
Weller, M., van den Bent, M., Preusser, M., Le Rhun, E., Tonn, J. C., Minniti, G., Bendszus, M., Balana, C., Chinot, O., Dirven, L., et al. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-020-00447-z · Cited by 2,048
Self-citationGlioblastoma and Other Primary Brain Malignancies in Adults
Schaff, L. R., & Mellinghoff, I. K. (2023) · JAMA · doi:10.1001/jama.2023.0023 · Cited by 1,411
Self-citationNetwork pharmacology: curing causal mechanisms instead of treating symptoms
Nogales, C., Mamdouh, Z. M., List, M., Kiel, C., Casas, A. I., & Schmidt, H. H. H. W. (2021) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2021.11.004 · Cited by 1,251
Weller, M., Wen, P. Y., Chang, S. M., Dirven, L., Lim, M. K., Monje, M., & Reifenberger, G. (2024) · Nature Reviews Disease Primers · doi:10.1038/s41572-024-00516-y · Cited by 693
Self-citationHara, T., Chanoch-Myers, R., Mathewson, N. D., Myskiw, C., Atta, L., Bussema, L., Eichhorn, S. W., Greenwald, A., Kinker, G. S., Rodman, C., et al. (2021) · Cancer Cell · doi:10.1016/j.ccell.2021.05.002 · Cited by 613
“Despite extensive efforts to translate the basic glioblastoma biology to patients, molecularly targeted therapies have largely failed in trials over the past decade (Gilbert et al., 2014; Wen et al., 2020).”
Metadata
- Authors
- Wen, P. Y., Weller, M., Lee, E. Q., Alexander, B. M., Barnholtz-Sloan, J. S., Barthel, F. P., Batchelor, T. T., Bindra, R. S., Chang, S. M., Chiocca, E. A., Cloughesy, T. F., DeGroot, J. F., Galanis, E., Gilbert, M. R., Hegi, M. E., Horbinski, C., Huang, R. Y., Lassman, A. B., Le Rhun, E., Lim, M., Mehta, M. P., Mellinghoff, I. K., Minniti, G., Nathanson, D., Platten, M., Preusser, M., Roth, P., Sanson, M., Schiff, D., Short, S. C., Taphoorn, M. J. B., Tonn, J.-C., Tsang, J., Verhaak, R. G. W., von Deimling, A., Wick, W., Zadeh, G., Reardon, D. A., Aldape, K. D., & van den Bent, M. J.
- Affiliations
- Brigham and Women's Hospital (US)
- University of Zurich (CH)
- Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA
- The Jackson Laboratory for Genomic Medicine (US)
- Yale University (US)
- University of California, San Francisco (US)
- University of California, Los Angeles (US)
- The University of Texas MD Anderson Cancer Center (US)
- Mayo Clinic (US)
- National Institutes of Health (US)
- Centre Hospitalier Universitaire Vaudois (CH)
- Northwestern University (US)
- NewYork–Presbyterian Hospital (US)
- University of Lille, Inserm, Neuro-oncology, General and Stereotaxic Neurosurgery service, University Hospital of Lille, Lille, France; Breast Cancer Department, Oscar Lambret Center, Lille, France and Department of Neurology & Brain Tumor Center, University Hospital and University of Zurich, Zurich, Switzerland
- Johns Hopkins University (US)
- Miami Cancer Institute, Miami, Florida, USA
- Memorial Sloan Kettering Cancer Center (US)
- University of Siena (IT)
- Heidelberg University (DE)
- Medical University of Vienna (AT)
- Centre National de la Recherche Scientifique (FR)
- University of Virginia (US)
- University of Leeds (GB)
- Leiden University Medical Center (NL)
- LMU Klinikum (DE)
- Neuropathology and Clinical Cooperation Unit Neuropathology, University Heidelberg and German Cancer Center, Heidelberg, Germany
- Princess Margaret Cancer Centre (CA)
- National Cancer Institute (US)
- Department of Neurology, Erasmus MC Cancer Institute, Rotterdam, the Netherlands
- Corresponding author
- Wen, Patrick Y
- Weller, Michael
- ORCID
- Wen, Patrick Y
- Weller, Michael
- Lee, Eudocia Quant
- Alexander, Brian M
- Barthel, Floris P
- Batchelor, Tracy T
- Bindra, Ranjit S
- Chang, Susan M
- Chiocca, E Antonio
- Cloughesy, Timothy F
- Galanis, Evanthia
- Gilbert, Mark R
- Hegi, Monika E
- Horbinski, Craig
- Huang, Raymond Y
- Lassman, Andrew B
- Lim, Michael
- Mehta, Minesh P
- Mellinghoff, Ingo K
- Minniti, Giuseppe
- Nathanson, David
- Platten, Michael
- Preusser, Matthias
- Roth, Patrick
- Sanson, Marc
- Schiff, David
- Short, Susan C
- Taphoorn, Martin J B
- Tonn, Joerg-Christian
- Tsang, Jonathan
- Verhaak, Roel G W
- Wick, Wolfgang
- Zadeh, Gelareh
- Reardon, David A
- Aldape, Kenneth D
- Venue
- Neuro-Oncology
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-04-24
- Volume
- 22
- Issue
- 8
- Pages
- 1073-1113
- ISSN
- 1522-8517 (ISSN-L)
- 1523-5866
- PMC
- PMC7594557
- OpenAlex
- W3020099303
- Cited by
- 1,168
- References
- 334
- Citations by year
- 2026: 166 · 2025: 215 · 2024: 242 · 2023: 204 · 2022: 194 · 2021: 118 · 2020: 28
- FWCI
- 71.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Neuro-Oncology (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion, other-oa)
- SERVAL (Université de Lausanne) (acceptedVersion, other-oa)
- Leiden Repository (Leiden University) (submittedVersion, cc-by-nc)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (submittedVersion)
- IRIS (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion, other-oa)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- HAL (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- JuSER (Forschungszentrum Jülich) (submittedVersion)
- LillOA (Université de Lille (University Of Lille)) (submittedVersion)
- The Mouseion at the JAXlibrary (Jackson Laboratory) (submittedVersion)
- RePub (Erasmus University Rotterdam) (submittedVersion)
- Use Siena air (University of Siena) (submittedVersion)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Funders
- University of Leeds
- National Institutes of Health (UL1TR001863)
- National Cancer Institute (P01CA069246, P30CA008748, P50CA211015, P30CA016672, P01CA163205)
- National Institute of Neurological Disorders and Stroke (R35NS105109)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Oncology › Glioma Diagnosis and Treatment
- Health Sciences › Medicine › Oncology › Ovarian cancer diagnosis and treatment
- Health Sciences › Medicine › Hematology › Chronic Lymphocytic Leukemia Research
- Keywords
- glioblastoma, IDH-wildtype glioblastoma, adult brain tumors, molecular pathogenesis, targeted therapy, DNA damage response, metabolic therapy, immunotherapy, viral therapy, treatment management
- MeSH terms
- Brain Neoplasms, Glioblastoma, Humans, Isocitrate Dehydrogenase, Randomized Controlled Trials as Topic, Clinical Trials, Phase III as Topic, Chemoradiotherapy
About these checks
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