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Cited by 406

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

A Review of the Global Burden, New Diagnostics, and Current Therapeutics for Amebiasis

Open access
Shirley, Debbie-Ann T, Farr, Laura, Watanabe, Koji, Moonah, Shannon·2018·Open Forum Infectious Diseases

Abstract

Amebiasis, due to the pathogenic parasite Entamoeba histolytica, is a leading cause of diarrhea globally. Largely an infection of impoverished communities in developing countries, amebiasis has emerged as an important infection among returning travelers, immigrants, and men who have sex with men residing in developed countries. Severe cases can be associated with high case fatality. Polymerase chain reaction–based diagnosis is increasingly available but remains underutilized. Nitroimidazoles are currently recommended for treatment, but new drug development to treat parasitic agents is a high priority. Amebiasis should be considered before corticosteroid therapy to decrease complications. There is no effective vaccine, so prevention focuses on sanitation and access to clean water. Further understanding of parasite biology and pathogenesis will advance future targeted therapeutic and preventative strategies.

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Registry

Crossref · 10.1093/ofid/ofy161

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Metadata

Authors
Shirley, D.-A. T., Farr, L., Watanabe, K., & Moonah, S.
Venue
Open Forum Infectious Diseases
Published
2018-07-01
Volume
5
Issue
7
Pages
ofy161-ofy161
ISSN
2328-8957 (ISSN-L)
OpenAlex
W2884525607
Cited by
406
References
32
FWCI
25.42
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: A Review of the Global Burden, New Diagnostics, and Current Therapeutics for Amebiasis. https://app.cochat.ai/papers/10.1093/ofid/ofy161
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Shirley, D.-A. T., Farr, L., Watanabe, K., & Moonah, S. (2018). A Review of the Global Burden, New Diagnostics, and Current Therapeutics for Amebiasis. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofy161

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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