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Microsatellites: Evolution and Applications
Abstract
Microsatellites are short stretches of repeated DNA, found in most genomes, that show exceptional variability in humans and most other species. This variability has made microsatellites the genetic marker of choice for most applications, including genetic mapping and studies of the evolutionary connections between species and populations. This book brings together an international group of scientists currently working in microsatellites. Their contributions provide a detailed description of microsatellite biology, focusing on their mutation properties, generation, decay, and possible functional roles. They introduce the theoretical models that underpin the most popular methods for analysing the information that microsatellites can yield, including methods for estimating coalescent times, population divergences, and migration. Finally, the book describes the various ways in which the potential of microsatellites is being harnessed in a range of applications including medical genetics, forensics, genetic mapping, the analysis of human evolution, and conservation genetics.
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Cited by
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Sabeti, P. C., Reich, D. E., Higgins, J. M., Levine, H. Z. P., Richter, D. J., Schaffner, S. F., Gabriel, S. B., Platko, J. V., Patterson, N. J., McDonald, G. J., et al. (2002) · Nature · doi:10.1038/nature01140 · Cited by 2,106
Use of Unlinked Genetic Markers to Detect Population Stratification in Association Studies
Pritchard, J. K., & Rosenberg, N. A. (1999) · The American Journal of Human Genetics · doi:10.1086/302449 · Cited by 1,198
Rosenberg, N. A. (2011) · Human Biology · doi:10.3378/027.083.0601 · Cited by 100
Tatarenkov, A., Ring, B. C., Elder, J. F., Bechler, D. L., & Avise, J. C. (2010) · PLoS ONE · doi:10.1371/journal.pone.0012863 · Cited by 89
Genome-Wide Analysis of Simple Sequence Repeats in Marine Animals—a Comparative Approach
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Metadata
- Publisher
- Oxford University PressOxford
- Published
- 1999-06-10
- OpenAlex
- W27851543
- Cited by
- 1,047
- References
- 0
- FWCI
- 36.43
- Type
- book
- Language
- en
- Open access
- closed
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