The Origins of Life: From the birth of life to the origin of language
Abstract
Abstract Living organisms are astonishingly complex. And the more we know about them - their biochemistry, their anatomy, their behaviour - the more astonishing are the detailed adaptations that we discover. How could this complexity have arisen? Most of us are familiar with Darwin's theory of evolution by natural selection. The idea behind it being that, in nature, those individuals best able to survive and reproduce will transmit the characteristics that enabled them to do so to their offspring, leading to the evolution of traits beneficial to the organism. Although Darwin's idea is simple - perhaps because it is so simple - it is hard to believe that it is able to explain the complexity of the living world. We can breed cows that produce more milk compared with earlier generations, say, but we cannot breed pigs that fly, or horses that can talk: there would be no promising variants that we could select and breed from. Where, then, does the variation come from that has made possible the evolution of ever-increasing complexity in the wonderfully adapted organisms we see around us? In answering this central question, John Maynard Smith and Eors Szathmary present for a general readership a novel picture of evolution. Their basic idea is that evolution depends on changes in the information that is passed between generations, and that there have been a number of 'major transitions' in the way that information is stored and transmitted. These transitions include the appearance of the first replicating molecules - the origin of life itself; the origin of cells; reproduction by sexual means; the appearance of multicellular plants and animals; the emergence of cooperation and of animal societies; and the unique language ability of humans. Here, then, is an accessible account of contemporary biology on the grandest scale, from the birth of life to the origin of language. Containing many original ideas, and covering many of the most fundamental ideas in biology, this important and deeply interesting book will appeal both to readers with little prior knowledge of science and to biologists themselves.
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Information in a biological context must exist within 'meaning'.
“Information in a biological context must exist within ‘meaning’ [46].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [46]
A small hairpin RNA molecule with specific terminal base sequences acquired the corresponding amino acid as a cofactor to improve the catalytic range and efficiency to become initial ribozymes.
“This small hairpin RNA molecule with specific terminal base sequences acquired the corresponding amino acid as a ‘cofactor’ to improve the catalytic range and efficiency to become initial ribozymes [46].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [46]
The functional enzyme for binding an amino acid to its corresponding tRNA was pre-aaRS from the beginning, not a ribozyme.
“Since various enzymes were available in the Peptide/RNA world, we propose that the functional enzyme for binding an amino acid to its corresponding tRNA was pre-aaRS from the beginning, not ribozyme, as previously suggested by other workers [46].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [46]
Ribozymes would have been in greater need of cofactors than protein enzymes, because without them the range of reactions they can catalyze is much smaller.
“Ribozymes would have been in greater need of cofactors than protein enzymes, because, without them, the range of reactions that they can catalyze is much smaller [46].”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [46]
Amino acids that are used more often in proteins are specified by a greater number of different codons.
“Similarly, amino acids that are used more often in proteins are specified by a greater number of different codons.”
From The Origin of Prebiotic Information System in the Peptide/RNA World: A Simulation Model of the Evolution of Translation and the Genetic Code (2019) · cites this paper as [46]
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- Authors
- Maynard Smith, J., & SzathmáRy, E.
- ORCID
- SzathmáRy, EöRs
- Publisher
- Oxford University PressOxford
- Published
- 1999-03-04
- OpenAlex
- W4388277938
- Cited by
- 334
- References
- 0
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 6 · 2023: 13 · 2022: 7 · 2021: 5 · 2020: 23 · 2019: 25 · 2018: 9 · 2017: 7 · 2016: 3 · 2015: 4 · 2014: 7 · 2013: 9 · 2012: 11
- FWCI
- 9.24
- Type
- book
- Language
- en
- Open access
- closed
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Keywords
- origin of life, major transitions, evolution of complexity, information transmission, origin of cells, sexual reproduction, multicellularity, cooperation, animal societies, origin of language, Darwinian evolution, John Maynard Smith
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