Cited by 71Nutritional Studies and DietNutrition, Health and Food BehaviorMenopause: Health Impacts and Treatments

The Women's Health Trial Feasibility Study in Minority Populations: Changes in Dietary Intakes

Coates, R. J., Bowen, D. J., Kristal, A. R., Feng, Z., Oberman, A., Hall, W. D., George, V., Lewis, C. E. +5 more·1999·American Journal of Epidemiology

Abstract

This randomized clinical trial examined the feasibility of low-fat dietary interventions among postmenopausal women of diverse backgrounds. During 1992-1994, 2,208 women aged 50-79 years, 28% of whom were black and 16% Hispanic, enrolled at clinics in Atlanta, Georgia, Birmingham, Alabama, and Miami, Florida. Intervention/support groups met periodically with a nutritionist to reduce fat intake to 20% of energy and to make other diet modifications. At 6 months postrandomization, the intervention group reduced fat intake from 39.7% of energy at baseline to 26.4%, a reduction of 13.3% of energy, compared with 2.3% among controls. Saturated fatty acid and cholesterol intakes were reduced, but intakes of fruits and vegetables, but not grain products, increased. Similar effects were observed at 12 and 18 months. Black and non-Hispanic white women had similar levels of reduction in fat, but the decrease in Hispanic women was less. Changes did not vary significantly by education. While bias in self-reported intakes may have resulted in somewhat overestimated changes in fat intake, the reported reduction was similar to the approximately 10% of energy decrease found in most trials and suggests that large changes in fat consumption can be attained in diverse study populations and in many subgroups.

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  1. Prentice RL. Dietary fat reduction as a hypothesis for the pre- vention of postmenopausal breast cancer, and a discussion of hypothesis testing strategies. In: American Institute for Cancer Research, ed. Diet and breast cancer. New York: Plenum Press, 1994:25-33.
  2. Chlebowski RT, Blackburn GL, Buzzard IM, et al. Adherence to a dietary fat intake reduction program in postmenopausal women receiving therapy for early breast cancer. J Clin Oncol 1993; 11:2072-80.
  3. Kristal AR, Shattuck AL, Williams A. Food frequency ques- tionnaires for diet intervention research. In: Proceedings of the 17th National Nutrient Databank Conference, June 7-10, 1992, Baltimore, MD. Washington, DC: International Life Sciences Institute, 1994:110-25.
  4. Snedecor GW, Cochran WG. Statistical methods. 8th ed. Ames, IA: Iowa State University Press, 1989.

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Authors
Coates, R. J., Bowen, D. J., Kristal, A. R., Feng, Z., Oberman, A., Hall, W. D., George, V., Lewis, C. E., Kestin, M., Davis, M., Evans, M., Grizzle, J. E., & Clifford, C. K.
Affiliations
  • Centers for Disease Control and Prevention (US)
  • Fred Hutch Cancer Center (US)
  • University of Alabama at Birmingham (US)
  • Emory University (US)
  • University of Miami (US)
  • National Institutes of Health (US)
Corresponding author
Coates, R. J.
Venue
American Journal of Epidemiology
Published
1999-06-15
Volume
149
Issue
12
Pages
1104-1112
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
OpenAlex
W2015345200
Cited by
71
References
35
Citations by year
2022: 1 · 2021: 1 · 2020: 1 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 6 · 2013: 4 · 2012: 3
FWCI
4.35
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal of Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • University of Miami
  • National Institutes of Health (n01cn025427-010, n01cn025426-001, n01cn025425-001)
  • National Heart, Lung, and Blood Institute
  • National Cancer Institute (N01-CN25427, N01-CN-25426, N01-CN25425)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Keywords
postmenopausal women, minority groups, dietary fat intake, saturated fatty acids, cholesterol intake, fruit and vegetable intake, Hispanic women, Black women, self-reported dietary intake, trial feasibility
MeSH terms
Aged, Alabama, Energy Intake, Dietary Fats, Feasibility Studies, Female, Florida, Georgia, Humans, Middle Aged, Minority Groups, Nutrition Surveys, Women's Health

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