Cited by 118Workplace Health and Well-beingMaternal Mental Health During Pregnancy and PostpartumOccupational Health and Safety in Workplaces

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Psychologic Stress in the Workplace and Spontaneous Abortion

Fenster, Laura, Schaefer, Catherine, Mathur, Ashwini, Hiatt, Robert A., Pieper, Carl, Hubbard, Alan E., Von Behren, Julie, Swan, Shanna H.·1995·American Journal of Epidemiology

DOI 10.1093/oxfordjournals.aje.a117576

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Abstract

The relation of work-related psychologic stress to spontaneous abortion was examined in a prospective study of 3,953 pregnant, employed members of a prepaid health plan in California, recruited between 1990 and 1991. Information on occupation, psychologic stress-related factors at work, social support at work, physical exertion at work, life events, pregnancy worries, and potential confounders was obtained by a telephone interview. Psychologic job stress and social support at work were assessed using an abbreviated version of the instrument developed by Karasek and colleagues (Los Angeles: University of Southern California, 1986). Results from the multivariate model indicated that, overall, stressful work was not associated with an increased risk of spontaneous abortion. However, interactions were observed between stressful work and maternal age over 32 years (p = 0.04), cigarette smoking (p = 0.02), and primigravidity (p = 0.06). Relative to the odds ratio for stressful work in young, nonsmoking, multigravid women without a history of two or more spontaneous abortions, the odds ratios for spontaneous abortion given stressful work were higher by 2.45 (95% confidence interval (CI) 1.03-5.81) for older women, 2.96 (95% CI 1.16-7.52) for smokers, and 2.27 (95% CI 0.97-5.27) for primigravid women.

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Authors: Fenster, L., Schaefer, C., Mathur, A., Hiatt, R. A., Pieper, C., Hubbard, A. E., Von Behren, J., & Swan, S. H.
Affiliations: California Health and Human Services Agency (US)
Kaiser Permanente (US)
Department of Health Services (US)
Duke University (US)
ORCID: Schaefer, Catherine
Hiatt, Robert A.
Pieper, Carl
Hubbard, Alan E.
Swan, Shanna H.
Venue: American Journal of Epidemiology
Publisher: Oxford University Press (OUP)
Published: 1995-12-01
Volume: 142
Issue: 11
Pages: 1176-1183
ISSN: 0002-9262 (ISSN-L)
1476-6256
DOI: 10.1093/oxfordjournals.aje.a117576
OpenAlex: W2142686474
Cited by: 118
References: 26
Citations by year: 2026: 1 · 2025: 2 · 2024: 2 · 2023: 6 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 3 · 2018: 5 · 2017: 4 · 2015: 4 · 2014: 4 · 2013: 3 · 2012: 2
FWCI: 10.91
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Epidemiology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (R3MH50508A)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Workplace Health and Well-being
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational Health and Safety in Workplaces
Keywords: psychological stress, occupational stress, miscarriage, pregnancy, social support at work, maternal age, cigarette smoking, life events
MeSH terms: Abortion, Spontaneous, Adult, Female, Humans, Pregnancy, Pregnancy Outcome, Prospective Studies, Risk Factors, Social Support, Stress, Psychological, Confounding Factors, Epidemiologic, Multivariate Analysis, Logistic Models, Occupational Exposure, Workplace

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Psychologic Stress in the Workplace and Spontaneous Abortion

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