Cited by 94Cardiac pacing and defibrillation studiesCardiac electrophysiology and arrhythmiasCardiovascular Syncope and Autonomic Disorders

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Chronic sinus node disease: natural course and indications for pacing

RASMUSSEN, K.·1981·European Heart Journal

DOI 10.1093/oxfordjournals.eurheartj.a061236

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Abstract

The natural history of sinus node disease has been analysed from reported as well as original data. Because of the widespread use of pacemakers in sinus node disease the perfect study of its true prognosis will probably never be made. Nevertheless, available data strongly indicate that the outlook for identified patients with the disorder who do not have sever symptoms is favorable. Even for the severely symptomatic group, the prognosis seems to be much better than in atrioventricular conduction disease. Pacemaker implantations in this condition should therefore, in general, be restricted to the symptomatic patient in whom the symptoms have been shown to coincide with bradycardia. International differences in the extent of pacing use have been analysed from current statistics. It is concluded that different attitudes to pacing in sinus node disease account for a substantial part of these differences

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Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Hammill, C. W., Hayes, D. L., Hlatky, M. A., Newby, L. K., Richard, L., Freedman, R. A., Gettes, L. S., et al. (2008) · Cited by 2
Erregungsbildungs- und Erregungsleitungsstörungen
Kalusche, D., & Csapo, G. (1996) · Springer eBooks · doi:10.1007/978-3-642-97605-6_25 · Cited by 2
Benefits of Rate-Responsive Pacing in Patients with Sick Sinus Syndrome
Nishino, M., Ito, T., Miyawaki, M., et al. (1994) · Angiology · doi:10.1177/000331979404500504 · Cited by 2
“AT was determined by the V-slope method,11>12 in addition to the following conventional criterial3: (1) VE/VC02 increases after being stable or decreases while the VE/V02 remains constant or is decreasing; (2) the gas exchange ratio, which was stable or slowly rising, begins to increase more steeply.”
Method
The Values and Limitations of Deductive Analysis and Electrophysiological Testing in Patients with Sinoatrial Arrhythmias
Schweitzer, P., & Mark, H. (1984) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1984.tb04925.x · Cited by 2
Pearls and Pitfalls: Severe Bradycardia
Cejin, M. C., Koyfman, A., & Long, B. (2025) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2025.11.002 · Cited by 1
2018 KHRS guideline for the evaluation and management of syncope-Part 1
Park, J., Cha, M.-J., Kim, D. H., Kim, Y. R., Mun, H. S., Bae, E. J., Seo, D. W., Song, M. K., Ahn, J., Yoon, H. D., et al. (2018) · International Journal of Arrhythmia · doi:10.18501/arrhythmia.2018.009 · Cited by 1
2018 KHRS guideline for the evaluation and management of syncope-Part 2
Kim, Y. R., Chun, K. J., Kim, J. S., Mun, H. S., Park, J., Seo, D. W., Song, M. K., Ahn, J. H., Yoon, H. J., Lee, D. I., et al. (2018) · International Journal of Arrhythmia · doi:10.18501/arrhythmia.2018.010 · Cited by 1
A single-center outcome of choosing catheter ablation as the initial treatment in tachycardia–bradycardia syndrome and a new predictive factor for pacemaker implantation
Kim, H. R., Kim, J., Kim, J. Y., Park, S.-J., Park, K., & On, Y. K. (2024) · International Journal of Arrhythmia · doi:10.1186/s42444-024-00126-5 · Cited by 2
“Unlike correctable extrinsic factors, intrinsic SA node disease is characterized by irreversible fibrotic tissue changes [13].”
Background
Papel da atividade física na avaliação e tratamento da insuficiência cardíaca crônica
Serra, S. M. (2001) · Revista Brasileira de Medicina do Esporte · doi:10.1590/s1517-86922001000100005 · Cited by 1
Differential Diagnosis in Syncope and Epilepsy: Clinical Neurophysiological and Cardiological Aspects
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Erregungsbildungs-und Erregungsleitungsstörungen
Kalusche, D., & Csapo, G. (2004) · Springer eBooks · doi:10.1007/978-3-642-18649-3_18 · Cited by 1
Tratamiento de las bradiarritmias. Indicaciones de empleo de f?rmacos. Empleo de procedimientos no farmacol?gicosmarcapasos
Alberola, A. G., Muoz, J. J. S., Mas, M. V., & Chvarri, M. V. (2005) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/s0211-3449(05)73741-3
Atrial Demand Pacing in Patients with Symptomatic Sick Sinus Syndrome.
Lee, W.-L., Kong, C. W., Wang, J. J., et al. (1994) · Japanese Heart Journal · doi:10.1536/ihj.35.625
Electrophysiologic effects of intravenous xamoterol in patients with sinus node dysfunction
Marneffe, M. D., Waterschoot, P., Bernard, A., et al. (1990) · Cardiovascular Drugs and Therapy · doi:10.1007/bf01857764
“A l t h o u g h artificial pacing has been recognized as a t rea tment of choice for symptomatic sinus node dysfunction [1-3], medical therapy may be useful as a fu'st approach to patients with minimal symptoms.”
Background
Clinical Aspects of Cardiac Pacing for Bradyarrhythmias
Ruiter, J. H. (1992) · RePub (Erasmus University Rotterdam) · doi:10.13140/rg.2.2.17317.29925
Chapter 27 Bradycardia
Vardas, P. E., Mavrakis, H. E., & Toff, W. D. (2009)
Trends in Cardiovascular Devices
Semples, S. (2008) · Journal of Clinical Engineering · doi:10.1097/01.jce.0000337791.71923.e8
Surgery and Society of Thoracic Surgeons Developed in Collaboration With the American Association for Thoracic for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices) (Writing Committee to Revise the ACC/AHA/NASPE 2002 Guideline Update Cardiology/American Heart Association Task Force on Practice Guidelines Abnormalities: Executive Summary: A Report of the American College of ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm
Sweeney, M. O., Schoenfeld, M. H., Silka, M. J., Stevenson, L. W., Hammill, S. C., Hayes, D. L., Hlatky, M. A., Newby, L. K., Freedman, A. L., Gettes, L. S., et al. (2010)
Podsumowanie wskazań do implantacji układów stymulujących serce
Załuska, R., Bobruk, M., Bobruk, M., Grabowski, M., & Bobruk, M. (2019) · Choroby Serca i Naczyń · doi:10.5603/chsin.2019.0041
Antibradykarde Stimulation: Prognose, Hämodynamik, Indikationen
Stangl, K., & Wirtzfeld, A. (1990) · Steinkopff eBooks · doi:10.1007/978-3-642-85388-3_1
Prospektive randomisierte Studie zum Vergleich von resorbierbarer und nicht-resorbierbarer Intrakutannaht bei der Implantation von Herzschrittmachern
Zezyk, C. (2022) · doi:10.21248/gups.65248
Sinus Node Dysfunction
Benditt, D. G., Sakaguchi, S., Lurie, K. G., & Lü, F. (2007) · Springer eBooks · doi:10.1007/978-1-84628-715-2_93 · Cited by 7
“Ambulatory ECG (AECG) recordings, exercise testing, and, to a much lesser extent, pharmacologic assessment of sinus node autonomic control are techniques of relatively longstanding, and remain the principal noninvasive techniques used in the diagnosis of suspected SND. Ambulatory ECG monitoring comprises a range of te…”
BackgroundInfluential
Erregungsbildungs- und Erregungsleitungsstörungen
Kalusche, D., & Csapo, G. (1989) · Springer eBooks · doi:10.1007/978-3-642-97060-3_27

Authors: RASMUSSEN, K.
Affiliations: University Hospital of North Norway (NO)
Corresponding author: RASMUSSEN, K.
Venue: European Heart Journal
Publisher: Oxford University Press (OUP)
Published: 1981-12
Volume: 2
Issue: 6
Pages: 455-459
ISSN: 0195-668X (ISSN-L)
1522-9645
DOI: 10.1093/oxfordjournals.eurheartj.a061236
OpenAlex: W1925145848
Cited by: 94
References: 0
Citations by year: 2025: 2 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 5 · 2019: 2 · 2018: 9 · 2015: 2 · 2014: 7 · 2013: 3 · 2012: 2
FWCI: 3.14
Type: journal article
Language: en
Open access: closed
Locations: European Heart Journal (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
Keywords: natural history (disease), prognosis, cardiac pacing, pacemaker implantation, bradycardia, symptomatic patients
MeSH terms: Cardiac Pacing, Artificial, Chronic Disease, Death, Sudden, Epidemiologic Methods, Humans, Prognosis, Sick Sinus Syndrome

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Chronic sinus node disease: natural course and indications for pacing

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