Cited by 313

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

A Fast Algorithm for Joint Reconstruction of Ancestral Amino Acid Sequences

Pupko, Tal, Pe, Itsik, Shamir, Ron, Graur, Dan·2000·Molecular Biology and Evolution

Abstract

A dynamic programming algorithm is developed for maximum-likelihood reconstruction of the set of all ancestral amino acid sequences in a phylogenetic tree. To date, exhaustive algorithms that find the most likely set of ancestral states (joint reconstruction) have running times that scale exponentially with the number of sequences and are thus limited to very few taxa. The time requirement of our new algorithm scales linearly with the number of sequences and is therefore applicable to practically any number of taxa. A detailed description of the new algorithm and an example of its application to cytochrome b sequences are provided.

Overview

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Crossref · 10.1093/oxfordjournals.molbev.a026369

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1 of 1 references verified0 citation errors · 0 not checkable

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Citations

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Research works printed but not linked: 7

  1. 1971, Syst. Zool., 20, 406, 10.2307/2412116 · DOI
  2. 1992, Comput. Appl. Biosci., 8, 275
  3. 1990, J. Mol. Evol., 31, 151, 10.1007/BF02109483 · DOI
  4. 1996, J. Mol. Evol., 42, 313, 10.1007/BF02198858 · DOI
  5. 1987, Mol. Biol. Evol., 4, 406
  6. 1999, Mol. Biol. Evol., 16, 590, 10.1093/oxfordjournals.molbev.a026141 · DOI
  7. 1998, J. Mol. Evol., 47, 686, 10.1007/PL00006427 · DOI

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Metadata

Authors
Pupko, T., Pe, I., Shamir, R., & Graur, D.
Venue
Molecular Biology and Evolution
Published
2000-06-01
Volume
17
Issue
6
Pages
890-896
ISSN
  • 0737-4038
  • 1537-1719
Cited by
313
References
1
Language
en

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