Cited by 464Schizophrenia research and treatmentMental Health and PsychiatryPsychopathy, Forensic Psychiatry, Sexual Offending

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The Initial Prodrome in Schizophrenia: Searching for Naturalistic Core Dimensions of Experience and Behavior

Moller, P., Husby, R.·2000·Schizophrenia Bulletin

DOI 10.1093/oxfordjournals.schbul.a033442

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Abstract

The scientific exploration of prepsychotic detection and intervention in psychosis has just commenced. To identify developing psychosis at prodromal stages, it is important to learn how patients and families perceive initial prodromes naturalistically. We must understand better what we are going to detect, because the essential components of this phase, particularly the subjective experiences, remain unsettled. In a series of 19 first episode DSM-IV schizophrenia patients, we explore prodromal phenomena in depth and identify potential core dimensions. On the basis of our findings, we describe experiences and behaviors that appear to be essential components of initial prodromes. The subjects reported serious difficulties interpreting and talking about prodromal experiences at the time these occurred, causing delayed identification. We report detailed reasons for this, pointing out vulnerable aspects of at-risk assessments. From eight proposed groups of experiences, two are highlighted as tentative core dimensions: "disturbance of perception of self" and "extreme preoccupation by and withdrawal to overvalued ideas." Four potential dimensions of prodromal behavior are also identified: (1) quit school, university, or job, or major school truancy, (2) marked and lasting observable shift of interests, (3) marked and lasting social passivity, withdrawal, or isolation, and (4) marked and lasting change in global appearance or behavior. We argue that the findings, the phenomena, and their significance in prodromes are valid because they are logical and coherent in light of clinical experience as well as the empirical literature of a full century.

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“Indeed, deficits in play are core symptoms of neurodevelopmental disorders like autism spectrum disorder, attention-deficit/hyperactivity disorder, and early onset schizophrenia (Alessandri, 1992; Jones et al., 1994; Møller and Husby, 2000; Jordan, 2003; Helgeland and Torgersen, 2005), many of which also exhibit robus…”
Background
Beyond words: linguistic experience in melancholia, mania, and schizophrenia
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The Diagnosis of Psychosis
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Authors: Moller, P., & Husby, R.
Affiliations: Diakonhjemmet Hospital (NO)
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2000-01-01
Volume: 26
Issue: 1
Pages: 217-232
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/oxfordjournals.schbul.a033442
OpenAlex: W2137547795
Cited by: 464
References: 86
Citations by year: 2026: 8 · 2025: 8 · 2024: 12 · 2023: 18 · 2022: 16 · 2021: 13 · 2020: 15 · 2019: 18 · 2018: 15 · 2017: 21 · 2016: 19 · 2015: 21 · 2014: 24 · 2013: 17 · 2012: 22
FWCI: 16.61
Type: journal article
Language: en
Open access: closed
Locations: Schizophrenia Bulletin (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords: schizophrenia, prodromal symptoms
MeSH terms: Adolescent, Adult, Age Factors, Cognition Disorders, Female, Humans, Male, Psychiatric Status Rating Scales, Research Design, Schizophrenia, Schizophrenic Psychology, Self Concept, Sex Factors, Social Adjustment, Social Alienation, Reproducibility of Results, Age of Onset

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The Initial Prodrome in Schizophrenia: Searching for Naturalistic Core Dimensions of Experience and Behavior

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