Cited by 112Computational and Text Analysis MethodsEthics and Social Impacts of AITopic Modeling

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Perils and opportunities in using large language models in psychological research

Open access

Abstract

The emergence of large language models (LLMs) has sparked considerable interest in their potential application in psychological research, mainly as a model of the human psyche or as a general text-analysis tool. However, the trend of using LLMs without sufficient attention to their limitations and risks, which we rhetorically refer to as “GPTology”, can be detrimental given the easy access to models such as ChatGPT. Beyond existing general guidelines, we investigate the current limitations, ethical implications, and potential of LLMs specifically for psychological research, and show their concrete impact in various empirical studies. Our results highlight the importance of recognizing global psychological diversity, cautioning against treating LLMs (especially in zero-shot settings) as universal solutions for text analysis, and developing transparent, open methods to address LLMs’ opaque nature for reliable, reproducible, and robust inference from AI-generated data. Acknowledging LLMs’ utility for task automation, such as text annotation, or to expand our understanding of human psychology, we argue for diversifying human samples and expanding psychology’s methodological toolbox to promote an inclusive, generalizable science, countering homogenization, and over-reliance on LLMs.

Overview

AI snapshot

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TL;DR

The paper warns against “GPTology”—the hurried, unjustified use of large language models as replacements for human participants or as universal text-analysis tools in psychology. It combines review with empirical demonstrations showing LLM biases, reduced response variance, weak zero-shot annotation, and reproducibility problems, while arguing LLMs can still aid research if validated, fine-tuned, and used cautiously.

Key findings

  • GPT-3.5’s responses to the Moral Foundations Questionnaire-2 across 1,000 queries had 43–121 times smaller variance than human data across six moral domains (all *P*s < 0.001), and its moral-value network differed substantially from a diverse human sample (*N* = 3,902 from 19 populations).
  • Across self-report measures from over 43 countries, ChatGPT showed significantly less variance and demographic differences; for example, it was more agreeable than politically liberal (*d* = −0.230), conservative (*d* = −0.403), and moderate (*d* = −0.285) individuals, and endorsed less right-wing authoritarianism than male (*d* = 0.44), White (*d* = 0.35), and younger 18–24 (*d* = 0.49) participants.
  • For moral-language annotation of 2,983 social media posts, fine-tuned BERT achieved F1 = 0.48 and fine-tuned ChatGPT-3.5 achieved F1 = 0.53, outperforming zero-shot ChatGPT (F1 = 0.22), LIWC (F1 = 0.27), and few-shot ChatGPT (F1 = 0.32); zero-shot ChatGPT was over 10 times more likely to predict a text as moral compared with human raters (Δodds = +1,240%, *P* < 0.001).
  • Minor prompt changes significantly altered outputs: adding a study introduction to the Big Five Inventory reduced Openness (*d* = −0.30), Extraversion (*d* = −0.54), and Agreeableness (*d* = −0.14); a modified moral prompt changed care (−56%), equality (−62%), loyalty (−33%), authority (+71%), and purity (+164%) annotations.

Methods

  • The paper combines a critical review with original empirical analyses. It administered the MFQ-2 to GPT-3.5 1,000 times and compared responses with a culturally diverse human sample from 19 populations, then extended comparisons to self-report measures from over 43 countries, including Big Five Inventory (*N* = 3,924), Need for Closure (*N* = 315), Need for Cognition (*N* = 900), Right-wing authoritarianism (*N* = 1,020), Empathizing–Systemizing (*N* = 3,141), and Rational–Experiential Inventory (*N* = 1,456).
  • For text analysis, ChatGPT annotated 2,983 social media posts for moral language in zero-shot, few-shot, and fine-tuned settings; results were compared with fine-tuned BERT, LIWC, human raters, and Contextualized Construct Representation (CCR). The authors also tested prompt modifications and an open-source LLaMA-based pipeline.
  • Main analyses included variance comparisons, effect sizes (*d*), F1 scores, odds changes, inter-correlations and partial-correlation networks, and Dunnett’s tests.

Limitations

  • Stated: the authors note that LLMs are rapidly evolving and that the concerns raised “could already be mitigated in the near future”; they also caution that open-source models do not fully solve the black-box problem, prompting may be insufficient to close demographic bias gaps, fine-tuning is resource-intensive, and few-shot learning depends on example quality and stability.
  • Stated: closed-source models lack freely available past versions, and even added parameters such as “seed” do not guarantee reproducibility; “system_fingerprint” increases transparency but not reproducibility itself.
  • Evident from the text: the empirical demonstrations focus on GPT-3.5/ChatGPT and selected psychological measures and annotation tasks, so the specific numerical findings may not generalize to all LLMs, model versions, or research domains.

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Integrity signals

Registry

Crossref · 10.1093/pnasnexus/pgae245

Cites

113 of 113 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Figures

Fig. 1. ChatGPT vs. human moral judgments. Note: a) Distributions of moral judgments of humans (light blue) and GPT (light red) in six moral domains. Dashed lines represent averages. b) Inter-correlations between moral values in humans (N=3,902) and ChatGPT queries (N=1,000). c) Network of partial correlations between moral values based on a diverse sample of humans from 19 nations (30) and 1,000 queries of GPT. Blue edges represent positive partial correlations and red edges represent negative partial correlations.
Fig. 1. ChatGPT vs. human moral judgments. Note: a) Distributions of moral judgments of humans (light blue) and GPT (light red) in six moral domains. Dashed lines represent averages. b) Inter-correlations between moral values in humans (N=3,902) and ChatGPT queries (N=1,000). c) Network of partial correlations between moral values based on a diverse sample of humans from 19 nations (30) and 1,000 queries of GPT. Blue edges represent positive partial correlations and red edges represent negative partial correlations.CC BY · PubMed Central
Fig. 2. Comparing ChatGPT against humans grouped by political opinion for responses on the Big Five Inventory. Note: Figure shows the response distribution of humans and ChatGPT across the five-factor personality constructs and for different human demographics. Figure shows that ChatGPT gives significantly higher responses on Agreeableness, Conscientiousness and significantly lower responses on Openness and Neuroticism. Importantly, ChatGPT shows significantly less variance compared with all demographic groups on all personality dimensions.
Fig. 2. Comparing ChatGPT against humans grouped by political opinion for responses on the Big Five Inventory. Note: Figure shows the response distribution of humans and ChatGPT across the five-factor personality constructs and for different human demographics. Figure shows that ChatGPT gives significantly higher responses on Agreeableness, Conscientiousness and significantly lower responses on Openness and Neuroticism. Importantly, ChatGPT shows significantly less variance compared with all demographic groups on all personality dimensions.CC BY · PubMed Central
Fig. 3. Comparing ChatGPT against humans across various demographic variables for the Right-Wing-Authoritarianism scale. Note: Figure shows the response distribution of humans and ChatGPT on the RWA scale for different human demographics. ChatGPT shows significantly lower average RWA than male, white, and young participants but not explicitly liberal participants. Importantly, ChatGPT shows significantly less variance compared with all demographic groups.
Fig. 3. Comparing ChatGPT against humans across various demographic variables for the Right-Wing-Authoritarianism scale. Note: Figure shows the response distribution of humans and ChatGPT on the RWA scale for different human demographics. ChatGPT shows significantly lower average RWA than male, white, and young participants but not explicitly liberal participants. Importantly, ChatGPT shows significantly less variance compared with all demographic groups.CC BY · PubMed Central

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Claims the paper makes

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Show all 88 claims

  • It may state two separate claims as one. 38
  • Probably not a substantial claim. 17
51 of 51
  • The paper relies on this without support.

    LLMs are trained on vast amounts of data that can contain many of the items and tasks used in psychological experiments, leading the model to rely on its memory instead of making inferences.

    “Furthermore, LLMs are trained on vast amounts of data, which can contain many of the items and tasks used in psychological experiments, thus leading the model to rely on its memory instead of making inferences, exacerbating the problem above.”
  • The paper relies on this without support.

    LLMs largely operate as black-boxes.

    “However, unlike traditional agent-based models, which define the environment, agents, interactions, and their consequences to allow for inferences based on these parameters, LLMs largely operate as black-boxes.”
  • The paper relies on this without support.

    Fine-tuned small(er) language models for various tasks are now increasingly publicly available.

    “Fine-tuned small(er) language models for various tasks are now increasingly publicly available.”
  • The paper relies on this without support.

    There are more and more high-quality and specialized datasets available to researchers for fine-tuning language models themselves.

    “Similarly, there are more and more high-quality and specialized datasets available to researchers for fine-tuning language models themselves.”
  • The paper relies on this without support.

    Human annotations provide a valid ground truth for moral language classification.

    “We compared the annotations of all models against the “ground truth” of human raters.”
  • The paper relies on this without support.

    ChatGPT's behavior is representative of large language models generally.

    “Building on this perspective, we extend these recent studies by investigating ChatGPT’s ability to annotate moral language across three distinct settings: zero-shot, few-shot, and fine-tuned.”
  • The paper relies on this without support.

    The human annotator demographics and psychometrics provided for the test data are accurate and valid for assessing annotation bias.

    “We did so by using human annotator demographics and psychometrics provided for our test data (see Supplementary Materials for a detailed description of the experimental procedures).”
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Citations

Cites

Show all 62 references

Research works printed but not linked: 2

  1. Rumelhart, 1987, Parallel distributed processing: explorations in the microstructure of cognition: foundations, 45
  2. Radford, 2019, Language models are unsupervised multitask learners, OpenAI Blog, 1, 9

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Metadata

Authors
Abdurahman, S., Atari, M., Karimi-Malekabadi, F., Xue, M. J., Trager, J., Park, P. S., Golazizian, P., Omrani, A., & Dehghani, M.
Affiliations
  • University of Southern California (US)
  • Harvard University (US)
  • Massachusetts Institute of Technology (US)
Corresponding author
Atari, Mohammad
Venue
PNAS Nexus
Published
2024-06-28
Volume
3
Issue
7
Pages
pgae245-pgae245
ISSN
2752-6542 (ISSN-L)
OpenAlex
W4400678448
Cited by
111
References
62
Citations by year
2026: 51 · 2025: 54 · 2024: 6
FWCI
96.27
Type
journal article
Language
en
Open access
Locations
  • PNAS Nexus (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
  • DARPA INCAS (HR001121C0165)
  • AFOSR (A9550-23-1-0463)
Topics
  • Social Sciences › General Social Sciences › Computational and Text Analysis Methods
  • Physical Sciences › Computer Science › Artificial Intelligence › Ethics and Social Impacts of AI
  • Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
Keywords
large language models, psychological research methods, AI-generated data, text analysis, zero-shot learning, psychological diversity, sample diversity, reproducibility, AI ethics, ChatGPT, task automation, textual annotation, overreliance on AI

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