Prevention of suicidal behavior in diabetes: the role of primary care
Open accessAbstract
Studies in different countries suggest that the rates of suicide ideation, attempts and death are increased in patients with diabetes in comparison to the general population. Suicidal behavior in patients with diabetes is a significant but underappreciated problem. Elevated suicide risk in individuals with diabetes may be related to comorbid psychiatric disorders, particularly depression. Considerable evidence suggests a bidirectional relationship between diabetes and depression: individuals with diabetes are at elevated risk of developing depression and patients with depression are more likely to develop diabetes. Frequent comorbidity of diabetes and depression may be related to psychosocial and neurobiological factors. Other comorbid psychiatric conditions including anxiety and alcohol use disorders may also increase suicide risk in diabetes. Primary care physicians are likely the key to suicide prevention efforts in individuals with diabetes since they see almost half of individuals who die by suicide within 1 month of their suicide. The management of potentially suicidal patients with diabetes in primary care comprises six major components: management of diabetes and its complications, especially conditions associated with pain; diagnosis and treatment of comorbid psychiatric disorders; frequent assessment of suicide risk; restricting access to the means of suicide; specific treatments to reduce the predisposition to attempt suicide; and referral to psychiatric care. Suicide prevention in individuals with diabetes and other medical disorders is a difficult but critically important task.
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The rates of suicide and self-harm observed in the study are similar to those observed in the general population in England.
“Additionally, the rates of suicide and self-harm observed in our study are similar to those observed in the general population in England.31”
From Glucagon-like peptide-1 receptor agonists and risk of suicidality among patients with type 2 diabetes: active comparator, new user cohort study (2025) · cites this paper as [31]
Cites
Prevention of Firearm Suicide in the United States: What Works and What Is Possible
Mann, J. J., & Michel, C. A. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16010069 · Cited by 208 · see citing works
Farooqi, A., Gillies, C., Sathanapally, H., Abner, S., Seidu, S., Davies, M. J., Polonsky, W. H., & Khunti, K. (2022) · Primary Care Diabetes · doi:10.1016/j.pcd.2021.11.001 · Cited by 204 · see citing works
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Arillotta, D., Floresta, G., Guirguis, A., Corkery, J. M., Catalani, V., Martinotti, G., Sensi, S. L., & Schifano, F. (2023) · Brain Sciences · doi:10.3390/brainsci13111503 · Cited by 104 · see citing works
Shapiro, S. B., Yin, H., Yu, O. H. Y., Rej, S., Suissa, S., & Azoulay, L. (2025) · BMJ · doi:10.1136/bmj-2024-080679 · Cited by 49 · see citing works
- Authors
- Sher, L.
- Affiliations
- James J. Peters VA Medical Center (US)
- Corresponding author
- Sher, L
- ORCID
- Sher, L
- Venue
- QJM: An International Journal of Medicine
- Publisher
- Oxford University Press (OUP)
- Published
- 2022-07-21
- Volume
- 115
- Issue
- 12
- Pages
- 789-792
- ISSN
- 0033-5622 (ISSN-L)
- 1460-2725
- 1460-2393
- OpenAlex
- W4286489715
- Cited by
- 10
- References
- 2
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 4
- FWCI
- 2.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- QJM (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- suicide prevention, diabetes mellitus, depression, psychiatric comorbidity, suicide risk assessment, primary care, anxiety, alcoholism, diabetes complications
- MeSH terms
- Alcoholism, Diabetes Mellitus, Humans, Primary Health Care, Risk Factors, Suicide, Attempted, Comorbidity
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