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Remission in rheumatoid arthritis: agreement of the disease activity score (DAS28) with the ARA preliminary remission criteria
Abstract
OBJECTIVE: To determine which cut-off point in the RA disease activity score (DAS28) corresponds to fulfilment of the ARA criteria for clinical remission. METHODS: The disease activity of patients included in the Nijmegen RA inception cohort was systematically assessed every 3 months. For all visits, a modification of the ARA preliminary criteria for clinical remission was applied and the DAS28 was calculated. Receiver operating characteristic analysis was used to determine the cut-off point with maximum sensitivity and specificity in DAS28 corresponding with fulfilment of the modified ARA criteria. RESULTS: Three hundred and seventy-eight patients contributed 4378 visits. In 6.5% of the visits four of the five items and in 1.5% all five items of the modified ARA criteria were fulfilled. The optimal cut-off point for the DAS28 that corresponds to fulfilment of the modified ARA criteria was determined to be 2.66. CONCLUSION: DAS28 <2.6 corresponds to fulfilment of the preliminary ARA criteria for clinical remission in RA.
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Cited by
Treating rheumatoid arthritis to target: recommendations of an international task force
Smolen, J. S., Aletaha, D., Bijlsma, J. W. J., Breedveld, F. C., Boumpas, D., Burmester, G., Combe, B., Cutolo, M., de Wit, M., Dougados, M., et al. (2010) · Annals of the Rheumatic Diseases · doi:10.1136/ard.2009.123919 · Cited by 2,100
Abatacept for Rheumatoid Arthritis Refractory to Tumor Necrosis Factor α Inhibition
Genovese, M. C., Becker, J.-C., Schiff, M., Luggen, M., Sherrer, Y., Kremer, J., Birbara, C., Box, J., Natarajan, K., Nuamah, I., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa050524 · Cited by 1,241
Hyrich, K. L., Watson, K. D., Silman, A. J., Symmons, D. P. M., & Register, T. B. B. (2006) · Rheumatology · doi:10.1093/rheumatology/kel149 · Cited by 623
Nishimoto, N., Miyasaka, N., Yamamoto, K., Kawai, S., Takeuchi, T., Azuma, J., & Kishimoto, T. (2008) · Modern Rheumatology · doi:10.1007/s10165-008-0125-1 · Cited by 334
Sex differences in rheumatoid arthritis: more than meets the eye
van Vollenhoven, R. F. (2009) · BMC Medicine · doi:10.1186/1741-7015-7-12 · Cited by 326
Metadata
- Authors
- Fransen, J.
- Venue
- Rheumatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-07-13
- Volume
- 43
- Issue
- 10
- Pages
- 1252-1255
- ISSN
- 0263-7103 (ISSN-L)
- 1460-2172
- OpenAlex
- W2148357532
- Cited by
- 484
- References
- 0
- FWCI
- 8.83
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fransen, J. (2004). Remission in rheumatoid arthritis: agreement of the disease activity score (DAS28) with the ARA preliminary remission criteria. Rheumatology. https://doi.org/10.1093/rheumatology/keh297
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