Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 2,100

The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.

Treating rheumatoid arthritis to target: recommendations of an international task force

Open access
Smolen, Josef S, Aletaha, Daniel, Bijlsma, Johannes W J, Breedveld, Ferdinand C, Boumpas, Dimitrios, Burmester, Gerd, Combe, Bernard, Cutolo, Maurizio, de Wit, Maarten, Dougados, Maxime, Emery, Paul, Gibofsky, Alan, Gomez-Reino, Juan Jesus, Haraoui, Boulos, Kalden, Joachim, Keystone, Edward C, Kvien, Tore K, McInnes, Iain, Martin-Mola, Emilio, Montecucco, Carlomaurizio, Schoels, Monika, van der Heijde, Desirée·2010·Annals of the Rheumatic Diseases

Abstract

Background Aiming at therapeutic targets has reduced the risk of organ failure in many diseases such as diabetes or hypertension. Such targets have not been defined for rheumatoid arthritis (RA). Objective To develop recommendations for achieving optimal therapeutic outcomes in RA. Methods A task force of rheumatologists and a patient developed a set of recommendations on the basis of evidence derived from a systematic literature review and expert opinion; these were subsequently discussed, amended and voted upon by >60 experts from various regions of the world in a Delphi-like procedure. Levels of evidence, strength of recommendations and levels of agreement were derived. Results The treat-to-target activity resulted in 10 recommendations. The treatment aim was defined as remission with low disease activity being an alternative goal in patients with long-standing disease. Regular follow-up (every 1–3 months during active disease) with appropriate therapeutic adaptation to reach the desired state within 3 to a maximum of 6 months was recommended. Follow-up examinations ought to employ composite measures of disease activity which include joint counts. Additional items provide further details for particular aspects of the disease. Levels of agreement were very high for many of these recommendations (≥9/10). Conclusion The 10 recommendations are supposed to inform patients, rheumatologists and other stakeholders about strategies to reach optimal outcomes of RA based on evidence and expert opinion.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/ard.2009.123919

Cites

81 of 81 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 81 references

Cited by

See all 2,100

Metadata

Authors
Smolen, J. S., Aletaha, D., Bijlsma, J. W. J., Breedveld, F. C., Boumpas, D., Burmester, G., Combe, B., Cutolo, M., de Wit, M., Dougados, M., Emery, P., Gibofsky, A., Gomez-Reino, J. J., Haraoui, B., Kalden, J., Keystone, E. C., Kvien, T. K., McInnes, I., Martin-Mola, E., Montecucco, C., Schoels, M., & van der Heijde, D.
Venue
Annals of the Rheumatic Diseases
Publisher
Elsevier BV
Published
2010-05
Volume
69
Issue
4
Pages
631-637
ISSN
0003-4967 (ISSN-L)
OpenAlex
W2155109530
Cited by
2,100
References
81
FWCI
112.22
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Treating rheumatoid arthritis to target: recommendations of an international task force. https://app.cochat.ai/papers/10.1136/ard.2009.123919
The paper
Smolen, J. S., Aletaha, D., Bijlsma, J. W. J., Breedveld, F. C., Boumpas, D., Burmester, G., Combe, B., Cutolo, M., de Wit, M., Dougados, M., Emery, P., Gibofsky, A., Gomez-Reino, J. J., Haraoui, B., Kalden, J., Keystone, E. C., Kvien, T. K., McInnes, I., Martin-Mola, E., . . . van der Heijde, D. (2010). Treating rheumatoid arthritis to target: recommendations of an international task force. Annals of the Rheumatic Diseases. https://doi.org/10.1136/ard.2009.123919

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.