Association Between Specific Childhood Adversities and Symptom Dimensions in People With Psychosis: Systematic Review and Meta-Analysis
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Despite the accepted link between childhood abuse and positive psychotic symptoms, findings between other adversities, such as neglect, and the remaining dimensions in people with psychosis have been inconsistent, with evidence not yet reviewed quantitatively. The aim of this study was to systematically examine quantitatively the association between broadly defined childhood adversity (CA), abuse (sexual/physical/emotional), and neglect (physical/emotional) subtypes, with positive, negative, depressive, manic, and disorganized dimensions in those with psychosis. A search was conducted across EMBASE, MEDLINE, PsychINFO, and Cochrane Libraries using search terms related to psychosis population, CA, and psychopathological dimensions. After reviewing for relevance, data were extracted, synthesized, and meta-analyzed. Forty-seven papers were identified, including 7379 cases across 40 studies examining positive, 37 negative, 20 depressive, 9 disorganized, and 13 manic dimensions. After adjustment for publication bias, general adversity was positively associated with all dimensions (ranging from r = 0.08 to r = 0.24). Most forms of abuse were associated with depressive (ranging from r = 0.16 to r = 0.32), positive (ranging from r = 0.14 to r = 0.16), manic (r = 0.13), and negative dimensions (ranging from r = 0.05 to r = 0.09), while neglect was only associated with negative (r = 0.13) and depressive dimensions (ranging from r = 0.16 to r = 0.20). When heterogeneity was found, it tended to be explained by one specific study. The depressive dimension was influenced by percentage of women (ranging from r = 0.83 to r = 1.36) and poor-quality scores (ranging from r = -0.21 and r = -0.059). Quality was judged as fair overall. Broadly defined adversity and forms of abuse increase transdimensional severity. Being exposed to neglect during childhood seems to be exclusively related to negative and depressive dimensions suggesting specific effects.
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There are some levels of specificity between adversity subtypes and symptoms domains; for example, abuse is more related to positive symptoms while neglect is not.
“Evidence is showing that there are some levels of specificity between adversity subtypes and symptoms domains, for example, abuse is more related to positive symptoms while neglect is not (Alameda et al., 2021)”
From Can epigenetics shine a light on the biological pathways underlying major mental disorders? (2022) · cites this paper as Alameda et al., 2021
Cites
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,577 · see citing works
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378 · see citing works
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623 · see citing works
Stang, A. (2010) · European Journal of Epidemiology · doi:10.1007/s10654-010-9491-z · Cited by 17,396 · see citing works
Duval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099 · see citing works
Development and validation of a brief screening version of the Childhood Trauma Questionnaire
Bernstein, D. P., Stein, J. A., Newcomb, M. D., Walker, E., Pogge, D., Ahluvalia, T., Stokes, J., Handelsman, L., Medrano, M., Desmond, D., et al. (2003) · Child Abuse & Neglect · doi:10.1016/s0145-2134(02)00541-0 · Cited by 6,419 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
Raber, G., & Spokas, M. (2024) · doi:10.4135/9781071886229.n145 · Cited by 2,806 · see citing works
Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T., Viechtbauer, W., Read, J., van Os, J., & Bentall, R. P. (2012) · Schizophrenia Bulletin · doi:10.1093/schbul/sbs050 · Cited by 2,436 · see citing works
van Os, J., Linscott, R. J., Myin-Germeys, I., Delespaul, P., & Krabbendam, L. (2009) · Psychological Medicine · doi:10.1017/s0033291708003814 · Cited by 2,343 · see citing works
On the Use of Beta Coefficients in Meta-Analysis.
Peterson, R. A., & Brown, S. P. (2005) · Journal of Applied Psychology · doi:10.1037/0021-9010.90.1.175 · Cited by 1,643 · see citing works
The correlation coefficient: its values range between +1/-1, or do they?
Ratner, B. (2009) · Journal of Targeting, Measurement and Analysis for Marketing · doi:10.1057/jt.2009.5 · Cited by 1,612 · see citing works
Read, J., van Os, J., Morrison, A. P., & Ross, C. A. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00634.x · Cited by 1,534 · see citing works
Mandelli, L., Petrelli, C., & Serretti, A. (2015) · European Psychiatry · doi:10.1016/j.eurpsy.2015.04.007 · Cited by 549 · see citing works
Psychosis as a transdiagnostic and extended phenotype in the general population
van Os, J., & Reininghaus, U. (2016) · World Psychiatry · doi:10.1002/wps.20310 · Cited by 531 · see citing works
Relationships between trauma and psychosis: an exploration of cognitive and dissociative factors
Kilcommons, A. M., & Morrison, A. P. (2005) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2005.00623.x · Cited by 341 · see citing works
Bailey, T. H., Álvarez‐Jiménez, M., Garcia-Sanchez, A. M., Hulbert, C. A., Barlow, E., & Bendall, S. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx161 · Cited by 324 · see citing works
From adversity to psychosis: pathways and mechanisms from specific adversities to specific symptoms
Bentall, R. P., de Sousa, P., Varese, F., Wickham, S., Sitko, K., Haarmans, M., & Read, J. (2014) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-014-0914-0 · Cited by 320 · see citing works
Davies, C., Segre, G., Estradé, A., Radua, J., De Micheli, A., Provenzani, U., Oliver, D., Salazar de Pablo, G., Ramella-Cravaro, V., Besozzi, M., et al. (2020) · The Lancet Psychiatry · doi:10.1016/s2215-0366(20)30057-2 · Cited by 301 · see citing works
Self-citationChildhood adversities and psychosis: evidence, challenges, implications
Morgan, C., & Gayer-Anderson, C. E. (2016) · World Psychiatry · doi:10.1002/wps.20330 · Cited by 258 · see citing works
Self-citationImplementing PRISMA-P: recommendations for prospective authors
Moher, D., Stewart, L. A., & Shekelle, P. (2016) · Systematic Reviews · doi:10.1186/s13643-016-0191-y · Cited by 230 · see citing works
Childhood Abuse andthe Positive Symptoms of Schizophrenia
Ross, C. A., Anderson, G., & Clark, P. (1994) · Psychiatric Services · doi:10.1176/ps.45.5.489 · Cited by 197 · see citing works
The Relationship Between Dissociation and Symptoms of Psychosis: A Meta-analysis
Longden, E., Branitsky, A., Moskowitz, A. K., Berry, K., Bucci, S., & Varese, F. (2020) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaa037 · Cited by 170 · see citing works
van Nierop, M. M., Viechtbauer, W., Günther, N., van Zelst, C., de Graaf, R., ten Have, M., van Dorsselaer, S., Bak, M., Genetic Risk and OUtcome of Psychosis (GROUP) investigators, & van Winkel, R. (2014) · Psychological Medicine · doi:10.1017/s0033291714002372 · Cited by 169 · see citing works
A systematic review on mediators between adversity and psychosis: potential targets for treatment
Alameda, L., Rodríguez, V., Carr, E., Aas, M., Trotta, G., Marino, P., Vorontsova, N., Herane-Vives, A., Gadelrab, R., Spinazzola, E., et al. (2020) · Psychological Medicine · doi:10.1017/s0033291720002421 · Cited by 125 · see citing works
Self-citationvan Dam, D. S., van Nierop, M. M., Viechtbauer, W., Velthorst, E., van Winkel, R., Genetic Risk and Outcome of Psychosis (GROUP) investigators, Bruggeman, R., Cahn, W., de Haan, L., Kahn, R. S., et al. (2014) · Psychological Medicine · doi:10.1017/s0033291714001561 · Cited by 110 · see citing works
Reported History of Child Sexual Abuse in Schizophrenia
Lysaker, P. H., Beattie, N. L., Strasburger, A. M., & Davis, L. W. (2005) · The Journal of Nervous and Mental Disease · doi:10.1097/01.nmd.0000188970.11916.76 · Cited by 102 · see citing works
Quattrone, D., Forti, M. D., Gayer-Anderson, C. E., Ferraro, L., Jongsma, H. E., Tripoli, G., Cascia, C. L., Barbera, D. L., Tarricone, I., Berardi, D., et al. (2018) · Psychological Medicine · doi:10.1017/s0033291718002131 · Cited by 99 · see citing works
Self-citationSexual histories, attitudes, and behavior of schizophrenic and ?normal? women
Friedman, S., & Harrison, G. (1984) · Archives of Sexual Behavior · doi:10.1007/bf01542090 · Cited by 96 · see citing works
Impact of Interpersonal Trauma on the Social Functioning of Adults With First-Episode Psychosis
Stain, H. J., Brønnick, K., Hegelstad, W. T. V., Joa, I., Johannessen, J. O., Langeveld, J., Mawn, L., & Larsen, T. K. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt166 · Cited by 86 · see citing works
Şahin, S., Yüksel, Ç., Güler, J., Karadayı, G., Akturan, E., Göde, E., Özhan, A. A., & Üçok, A. (2013) · Early Intervention in Psychiatry · doi:10.1111/eip.12022 · Cited by 77 · see citing works
Relationship between childhood adversity and clinical and cognitive features in schizophrenia
McCabe, K., Maloney, E. A., Stain, H. J., Loughland, C. M., & Carr, V. J. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.01.023 · Cited by 65 · see citing works
Influence of early trauma on features of schizophrenia
Ruby, E., Rothman, K., Corcoran, C. M., Goetz, R. R., & Malaspina, D. (2015) · Early Intervention in Psychiatry · doi:10.1111/eip.12239 · Cited by 63 · see citing works
Schalinski, I., & Teicher, M. H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127151 · Cited by 58 · see citing works
Kumari, V., Gudjonsson, G. H., Raghuvanshi, S., Barkataki, I., Taylor, P. J., Sumich, A. L., Das, K., Kuipers, E., Ffytche, D. H., & Das, M. (2012) · European Psychiatry · doi:10.1016/j.eurpsy.2012.03.002 · Cited by 56 · see citing works
Mansueto, G., Schruers, K. R. J., Cosci, F., van Os, J., Alizadeh, B. Z., Bartels‐Velthuis, A. A., van Beveren, N. J. M., Bruggeman, R., Cahn, W., de Haan, L., et al. (2018) · Schizophrenia Research · doi:10.1016/j.schres.2018.11.028 · Cited by 56 · see citing works
Alameda, L., Golay, P., Baumann, P., Progin, P., Mebdouhi, N., Elowe, J., Ferrari, C., Kim, Q., & Conus, P. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw163 · Cited by 53 · see citing works
Self-citationPichot, P. (1986) · PubMed · Cited by 50 · see citing works
Alameda, L., Golay, P., Baumann, P., Ferrari, C., Kim, Q., & Conus, P. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m09947 · Cited by 49 · see citing works
Self-citationMurray, R. M., Mondelli, V., Stilo, S. A., Trotta, A., Sideli, L., Ajnakina, O., Ferraro, L., Vassos, E., Iyegbe, C. O., Schoeler, T., et al. (2020) · Schizophrenia Research · doi:10.1016/j.schres.2020.01.011 · Cited by 39 · see citing works
Self-citationUnravelling psychosis: psychosocial epidemiology, mechanism, and meaning.
Bebbington, P. (2015) · Europe PMC (PubMed Central) · doi:10.11919/j.issn.1002-0829.215027 · Cited by 38 · see citing works
Bendall, S., Jackson, H. J., & Hulbert, C. A. (2010) · Australian Psychologist · doi:10.1080/00050060903443219 · Cited by 33 · see citing works
Childhood adversities and clinical symptomatology in first-episode psychosis
Lindgren, M., Mäntylä, T. J. S., Rikandi, E., Torniainen‐Holm, M., Morales‐Muñoz, I., Kieseppä, T., Mantere, O., & Suvisaari, J. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.08.070 · Cited by 32 · see citing works
Seidenfaden, D., Knorr, U. B., Soendergaard, M. G., Poulsen, H. E., Fink‐Jensen, A., Jørgensen, M. B., & Jørgensen, A. (2016) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2016.09.009 · Cited by 24 · see citing works
Sayin, A., Yüksel, N., Konaç, E., Yılmaz, A., Doğan, B., Tönge, Ş., Şahiner, Ş. Y., & Menevşe, A. (2013) · DNA and Cell Biology · doi:10.1089/dna.2012.1894 · Cited by 7 · see citing works
Flagged first, then by citations
1 of the 46 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The schizophrenia syndrome, circa 2024: What we know and how that informs its nature
Tandon, R., Nasrallah, H. A., Akbarian, S., Carpenter, W. T., DeLisi, L. E., Gäebel, W., Green, M. F., Gur, R. E., Heckers, S., Kane, J. M., et al. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.11.015 · Cited by 196 · see citing works
Self-citationPrevalence of Adverse Childhood Experiences in Child Population Samples
Madigan, S. L., Thiemann, R. F., Deneault, A., Fearon, P. R. M., Racine, N. M., Park, J., Lunney, C. A., Dimitropoulos, G., Jenkins, S., Williamson, T. S., et al. (2024) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2024.4385 · Cited by 109 · see citing works
Michelini, G., Carlisi, C. O., Eaton, N. R., Elison, J. T., Haltigan, J. D., Kotov, R., Krueger, R. F., Latzman, R. D., Li, J. J., Levin-Aspenson, H. F., et al. (2024) · World Psychiatry · doi:10.1002/wps.21225 · Cited by 99 · see citing works
Can epigenetics shine a light on the biological pathways underlying major mental disorders?
Alameda, L., Trotta, G., Quigley, H., Rodriguez, V., Gadelrab, R., Dwir, D., Dempster, E., Wong, C. C. Y., & Forti, M. D. (2022) · Psychological Medicine · doi:10.1017/s0033291721005559 · Cited by 60 · see citing works
“Evidence is showing that there are some levels of specificity between adversity subtypes and symptoms domains, for example, abuse is more related to positive symptoms while neglect is not (Alameda et al., 2021) and that CU is associated with paranoia (Freeman et al., 2005).”
BackgroundSelf-citationCampodonico, C., Varese, F., & Berry, K. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-03808-3 · Cited by 49 · see citing works
Zhou, L., Sommer, I. E., Yang, P., Sikirin, L., van Os, J., Bentall, R. P., Varese, F., & Begemann, M. (2025) · American Journal of Psychiatry · doi:10.1176/appi.ajp.20240456 · Cited by 51 · see citing works
Psychosis superspectrum I: Nosology, etiology, and lifespan development
Jonas, K. G., Cannon, T. D., Docherty, A. R., Dwyer, D., Gur, R. C., Gur, R. E., Nelson, B., Reininghaus, U., & Kotov, R. (2024) · Molecular Psychiatry · doi:10.1038/s41380-023-02388-2 · Cited by 42 · see citing works
Fares-Otero, N., Alameda, L., Pfaltz, M., Martínez-Àran, A., Schäfer, I., & Vieta, E. (2023) · Psychological Medicine · doi:10.1017/s0033291723001678 · Cited by 29 · see citing works
Self-citationVarese, F., Sellwood, W., Pulford, D., Awenat, Y. F., Bird, L., Bhutani, G., Carter, L., Davies, L. M., Aseem, S., Davis, C., et al. (2023) · Psychological Medicine · doi:10.1017/s0033291723002532 · Cited by 32 · see citing works
Christy, A., Cavero, D., Navajeeva, S., Murray-O’Shea, R., Rodríguez, V., Aas, M., Trotta, G., Moudiab, S., Torres, N. G., Zamora, B., et al. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac105 · Cited by 29 · see citing works
Self-citationRosenfield, P., Jiang, D., & Pauselli, L. (2021) · Schizophrenia Research · doi:10.1016/j.schres.2021.06.005 · Cited by 27 · see citing works
Alameda, L., Liu, Z., Sham, P. C., Aas, M., Trotta, G., Rodríguez, V., Forti, M. D., Stilo, S. A., Kandaswamy, R., Arango, C., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02044-9 · Cited by 23 · see citing works
Self-citationSideli, L., Schimmenti, A., Barbera, D. L., Cascia, C. L., Ferraro, L., Aas, M., Alameda, L., Velthorst, E., Fisher, H. L., Caretti, V., et al. (2022) · Schizophrenia Bulletin · doi:10.1093/schbul/sbac004 · Cited by 19 · see citing works
Self-citationHuang, Y., Hu, H., Wang, L., Zhang, Y., Wang, X., Wang, Y., Wang, Y., Wang, Y., Lui, S. S. Y., & Chan, R. C. K. (2023) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2023.103598 · Cited by 18 · see citing works
A Transdiagnostic Network Analysis of Childhood Trauma and Psychopathology
Huang, Y., Liu, C., Zhang, J., Li, S., Wang, L., Hu, H., Cai, Y., Zhu, Z., Chu, M., Wang, Y., et al. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae137 · Cited by 17 · see citing works
Jin, Y., Xu, S., Wang, Y., Li, H., Wang, X., Xi, S., & Wang, Y. Y. (2022) · European Journal of Psychotraumatology · doi:10.1080/20008066.2022.2141508 · Cited by 18 · see citing works
Merritt, K., Laguna, P. A. L., Sethi, A., Drakesmith, M., Ashley, S. A., Bloomfield, M., Fonville, L., Perry, G., Lancaster, T., Dimitriadis, S. I., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02295-6 · Cited by 14 · see citing works
Alameda, L., Conus, P., Ramain, J., Solida, A., & Golay, P. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.11.027 · Cited by 14 · see citing works
Self-citationÜçok, A., Noyan, H., Gülöksüz, S., Saka, M. C., Alptekın, K., Atbaşoğlu, C., Akturan, E., Karadayı, G., Tatar, Z. B., Akdede, B. B., et al. (2024) · Psychological Medicine · doi:10.1017/s0033291724000540 · Cited by 13 · see citing works
Unraveling the Concept of Childhood Adversity in Psychosis Research: A Systematic Review
Sætren, S. S., Bjørnestad, J. R., Ottesen, A. A., Fisher, H. L., Olsen, D. A. S., Hølland, K., & Hegelstad, W. T. V. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae085 · Cited by 13 · see citing works
Gizdić, A., Sheinbaum, T., Kwapil, T. R., & Barrantes‐Vidal, N. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2222614 · Cited by 12 · see citing works
The role of interpersonal trauma and substance use in mental health: A large population-based study
Aas, M., Sideli, L., Franceschini, C., Alameda, L., Trotta, G., Coco, G. L., Musetti, A., & Schimmenti, A. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115712 · Cited by 12 · see citing works
Self-citationPeralta, V., de Jalón, E. G., Moreno-Izco, L., Peralta, D., Janda, L., Sánchez-Torres, A. M., Cuesta, M. J., & SEGPEPs group (2024) · Psychological Medicine · doi:10.1017/s0033291724001223 · Cited by 11 · see citing works
Brandt, J. M., Gregersen, M., Søndergaard, A., Krantz, M. F., Knudsen, C. B., Andreassen, A. K., Veddum, L., Ohland, J., Hjorthøj, C. R., Wilms, M., et al. (2023) · Psychological Medicine · doi:10.1017/s0033291722004020 · Cited by 11 · see citing works
Schnider, M., Jenni, R., Ramain, J., Camporesi, S., Golay, P., Alameda, L., Conus, P., Kim, Q., & Steullet, P. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02183-7 · Cited by 11 · see citing works
Self-citationChildhood emotional maltreatment and sensitivity to social rejection in emerging adults
Euteneuer, F., Lass‐Hennemann, J., Pfundmair, M., Salzmann, S., & Kuehl, L. K. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106604 · Cited by 11 · see citing works
Barnes, G., Emsley, R., Garety, P., & Hardy, A. (2023) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgad017 · Cited by 11 · see citing works
Coughlan, B., Duschinsky, R., Bakermans‐Kranenburg, M. J., Bakkum, L., Skinner, G. C. M., Markham, A., Beckwith, H., & van IJzendoorn, M. H. (2026) · JCPP Advances · doi:10.1002/jcv2.70081 · Cited by 9 · see citing works
Goh, K. K., Kanahara, N., Chiu, Y.-H., & Lu, M. (2023) · Psychological Medicine · doi:10.1017/s003329172300274x · Cited by 8 · see citing works
Stone, L., Millman, Z. B., Öngür, D., & Shinn, A. K. (2021) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgab050 · Cited by 8 · see citing works
Barnes, G. L., Emsley, R., Garety, P. A., & Hardy, A. (2021) · Psychosis · doi:10.1080/17522439.2021.2009903 · Cited by 8 · see citing works
Sparrow, R., & Fornells‐Ambrojo, M. (2024) · European Journal of Psychotraumatology · doi:10.1080/20008066.2024.2355829 · Cited by 7 · see citing works
Trauma and resistance to antipsychotic treatment in schizophrenia: A narrative review
Verdoux, H., Sibert, A., & Quilès, C. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114392 · Cited by 7 · see citing works
Alameda, L., Rodriguez, V., di Forti, M., Spinazzola, E., Trotta, G., Arango, C., Arrojo, M., Bernardo, M., Bobes, J., de Haan, L., et al. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03149-7 · Cited by 10 · see citing works
Self-citationCortisol and C-reactive protein (CRP) regulation in severe mental disorders
Inova, A., Birkenæs, V., Quintana, D. S., Ormerod, M. B. E. G., Ueland, T., Ueland, T., Djurovic, S., Andreassen, O. A., Steen, N. E., & Aas, M. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107272 · Cited by 7 · see citing works
Self-citationChildhood trauma and real-world social experiences in psychosis
Steenkamp, L. R., Parrish, E. M., Chalker, S. A., Badal, V. D., Pinkham, A. E., Harvey, P. D., & Depp, C. A. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2022.12.039 · Cited by 7 · see citing works
Hidalgo, A. P. C., Hammerton, G., Heron, J., Bolhuis, K., Madley‐Dowd, P., Tiemeier, H. W., van IJzendoorn, M. H., Zammit, S., & Jones, H. J. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae023 · Cited by 6 · see citing works
Neumann, E., Rixe, J., Drießen, M., & Juckel, G. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106372 · Cited by 6 · see citing works
Kiakos, D., Alameda, L., Lepreux, I., Conchon, C., Alerci, L., Gorgellino, M., Mebdouhi, N., Petrova, T., Golay, P., Empson, L. A., et al. (2025) · Schizophrenia · doi:10.1038/s41537-025-00620-2 · Cited by 5 · see citing works
Self-citationRisk factors of deficit and non-deficit schizophrenia: Results from a cross-sectional study
Cyran, A., Piotrowski, P., Samochowiec, J., Grąźlewski, T., & Misiak, B. (2022) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2022.05.005 · Cited by 5 · see citing works
Lui, S. S. Y., Wong, Y.-L., Huang, Y., Chau, B. C. L., Cheung, E. S. L., Wong, C. H. Y., Wong, R. W. K., Leung, S., Lam, J. P. H., & Chan, R. C. K. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104211 · Cited by 5 · see citing works
The impact of childhood trauma and cannabis use on paranoia: a structural equation model approach
Trotta, G., Spinazzola, E., Degen, H., Li, Z., Austin-Zimmerman, I., Leung, B. M., Lang, Y., Rodríguez, V., Aas, M., Sideli, L., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725101190 · Cited by 4 · see citing works
Self-citationEnthoven, A.-S. D., Gangadin, S. S., de Haan, L., Veling, W., de Vries, E. F. J., Doorduin, J., Begemann, M., & Sommer, I. E. (2023) · Psychological Medicine · doi:10.1017/s0033291723001824 · Cited by 4 · see citing works
Taylor, C. D. J., Helliwell, B. J., Coleman, R., Sutton, C., Hutton, P., Sylvestre, Y., Bird, L., Shields, G., KELLY, J. A., Brandwood-Spencer, T., et al. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf060 · Cited by 4 · see citing works
Golay, P., Empson, L. A., Mebdouhi, N., Conus, P., & Alameda, L. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.09.001 · Cited by 4 · see citing works
Self-citationLunding, S. H., Ueland, T., Aas, M., Høegh, M. C., Werner, M. C. F., Rødevand, L. N., Johansen, I. T., Hjell, G., Ormerod, M. B. E. G., Ringen, P. A., et al. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.09.041 · Cited by 4 · see citing works
Self-citationChildhood maltreatment and social functioning in psychotic disorders: a systematic review protocol
Fares‐Otero, N. E., Pfaltz, M. C., Rodríguez–Jiménez, R., Schäfer, I., & Trautmann, S. (2021) · European Journal of Psychotraumatology · doi:10.1080/20008198.2021.1943872 · Cited by 5 · see citing works
The Impact of Childhood Trauma on the Negative Symptoms of Schizophrenia
Ware, K., Misiak, B., Hamza, E. A., Nalla, S., & Moustafa, A. A. (2024) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001788 · Cited by 3 · see citing works
Aas, M., Andreassen, O. A., Gjerstad, J., Rødevand, L. N., Hjell, G., Johansen, I. T., Lunding, S. H., Ormerod, M. B. E. G., Lagerverg, T. V., Steen, N. E., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-40310-6 · Cited by 3 · see citing works
Self-citationChan, C. C., Dolgopolskaia, E.-S., Goldstein, K. E., Kowalchyk, M. L., Aladin, S., Challman, K. N., Ng, S., Reynolds, K., Russo, D., Kapil-Pair, K. N., et al. (2024) · Schizophrenia Bulletin · doi:10.1093/schbul/sbae209 · Cited by 3 · see citing works
Schaug, J. P., Storebø, O. J., Austin, S., Trauelsen, A., Pedersen, M. B., Haahr, U. H., & Simonsen, E. (2023) · Psychiatry Research Communications · doi:10.1016/j.psycom.2023.100112 · Cited by 3 · see citing works
Schaug, J. P., Storebø, O. J., Pedersen, M. B., Haahr, U., & Simonsen, E. H. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.11.005 · Cited by 2 · see citing works
Varese, F., Cartwright, K. L., Larkin, A., Sandys, M., Flinn, A., Newton, A., Lamonby, J., Samji, M., Holden, C., Bowe, S. E., et al. (2025) · Early Intervention in Psychiatry · doi:10.1111/eip.70095 · Cited by 2 · see citing works
Beyond Kraepelin: An Aetiological Approach to the Typology and Treatment of Psychosis
Murray, R. M., Alameda, L., Dima, A., & Oliver, D. (2026) · Springer eBooks · doi:10.1007/978-3-032-09475-9_25 · Cited by 2 · see citing works
Self-citationMisiak, B., Frydecka, D., Piotrowski, P., Rembacz, K. P., Bielawski, T., Samochowiec, J., Tyburski, E. M., Łaczmański, Ł., & Pawlak, E. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107062 · Cited by 2 · see citing works
Chabake, S. A., Daigneault, I., Giguère, C., & Lecomte, T. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.06.020 · Cited by 2 · see citing works
Yao, B., Hall, M., Tusuzian, E., Cohen, B. M., Öngür, D., & Chouinard, V. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.07.006 · Cited by 2 · see citing works
Grady, S., Crowley, N., Scott, S., Ndukwe, C. I., Donohoe, R., & Gaynor, K. (2025) · British Journal of Clinical Psychology · doi:10.1111/bjc.12554 · Cited by 1 · see citing works
Adewuya, A. O., Oladipo, O. E., Emsley, R. A., & Asmal, L. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.09.030 · Cited by 1 · see citing works
Todd, I. L., Orth, R. D., Savage, C. L. G., Gard, A. M., Bennett, M. E., & Blanchard, J. J. (2025) · Psychiatry Research · doi:10.1016/j.psychres.2025.116774 · Cited by 1 · see citing works
Adewuya, A. O., Oladipo, O. E., Emsley, R. A., & Asmal, L. (2026) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2026.107962 · Cited by 1 · see citing works
Childhood Adversities and Psychosis Across Populations: Insights From the 6-Country EU-GEI Study
Morgan, C., Gayer-Anderson, C. E., Sideli, L., Jongsma, H. E., Velthorst, E., Tarricone, I., Ferraro, L., Barbera, D. L., Cascia, C. L., Lasalvia, A., et al. (2026) · Schizophrenia Bulletin · doi:10.1093/schbul/sbag030 · Cited by 1 · see citing works
Self-citationWilliams, T. F., Freilich, C. D., Cowan, H. R., Docherty, A. R., Jonas, K. G., Martin, E. A., & Kotov, R. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.05.012 · Cited by 1 · see citing works
aktaş, S., & Kırlı, U. (2023) · Turkish Journal of Psychiatry · doi:10.5080/u27345 · Cited by 1 · see citing works
Fekih‐Romdhane, F., Hadathy, D. E., Malaeb, D. N., Barakat, H., & Hallit, S. R. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-06019-0 · Cited by 1 · see citing works
Associations Between Childhood Trauma and Social Cognition in Early Psychosis
Cavero, D., Jenni, R., Golay, P., Gorgellino, M., Klauser, P., Cleusix, M., Empson, L. A., Petrova, T., Lepreux, I., Conchon, C., et al. (2025) · Early Intervention in Psychiatry · doi:10.1111/eip.70052 · Cited by 1 · see citing works
Self-citationFeng, Z., Qiu, Y., Jiang, C., Lu, Y., Liu, Y., Li, M., & Li, J. (2025) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-025-02049-1 · Cited by 2 · see citing works
Lavín, V., Torrecilla, P., Kwapil, T. R., & Barrantes‐Vidal, N. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1655172 · Cited by 1 · see citing works
Risk factors of deficit and non-deficit schizophrenia: Results from a cross-sectional study
Cyran, A., Piotrowski, P., Samochowiec, J., Grąźlewski, T., & Misiak, B. (2022) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/j.rpsmen.2022.05.001 · Cited by 1 · see citing works
Childhood Trauma and Consequential Impact on Sleep
Aas, M., Hennion, V., Birkenæs, V., Alameda, L., & Étain, B. (2023) · Springer eBooks · doi:10.1007/978-3-031-31547-3_83 · Cited by 1 · see citing works
Self-citationLunding, S. H., Ueland, T., Aas, M., Høegh, M. C., Werner, M. C. F., Rødevand, L. N., Johansen, I. T., Hjell, G., Ormerod, M. B. E. G., Ringen, P. A., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4113866
Self-citationMultimethod Assessment of Psychosis and Psychotic Phenomena
Mihura, J. L., Kleiger, J. H., & Khadivi, A. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190092689.013.19
Childhood Trauma and Consequential Impact on Sleep
Aas, M., Hennion, V., Birkenæs, V., Alameda, L., & Étain, B. (2023) · Springer eBooks · doi:10.1007/978-3-030-98711-4_83-1
Self-citationTschoeke, S., Steinert, T., & Knoblauch, H. (2024) · International Journal of Law and Psychiatry · doi:10.1016/j.ijlp.2024.101973
Alameda, L. (2025) · BJPsych Open · doi:10.1192/bjo.2024.863
Self-citationLaffely, M., Grosu, C., Laaboub, N., Golay, P., Alameda, L., Conus, P., & Eap, C. B. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1627203
Self-citationFrom trauma to treatment: A scoping review of childhood bullying and its role in psychotic disorders
Nielsen, M. Ø., Hilker, R. W., & Rosenbaum, B. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.10.066
Alameda, L., Conchon, C., Sprüngli‐Toffel, E., Curtis, L., Meyer, N., Edan, A., Navarro, A. L., Devillé, C., Armando, M., Mebdouhi, N., et al. (2026) · L Encéphale · doi:10.1016/j.encep.2025.11.003
Self-citationKiakos, D., Alameda, L., Empson, L. A., Spanevello, C., Gorgellino, M., Alerci, L., Mebdouhi, N., Conus, P., & Vieira, S. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf253
Self-citationChristensen, M. J., Olesen, A. V., Ward, T., Hardy, A., Mainz, J., Thomas, N., Smith, L. C., Mariegaard, L. S., Nordentoft, M., Glenthøj, L. B., et al. (2026) · Psychological Medicine · doi:10.1017/s0033291726104437
Jelsma, A., de With, J., van der Pluijm, M., de Koning, M. B., Schirmbeck, F. N., & de Haan, L. (2026) · Psychological Medicine · doi:10.1017/s0033291726105492
Anyansi, T. E., & Wu, C. (2026) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2026.10.032
- Authors
- Alameda, L., Christy, A., Rodriguez, V., Salazar de Pablo, G., Thrush, M., Shen, Y., Alameda, B., Spinazzola, E., Iacoponi, E., Trotta, G., Carr, E., Ruiz Veguilla, M., Aas, M., Morgan, C., & Murray, R. M.
- Affiliations
- King's College London (GB)
- Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK
- Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, UK
- Hôpital de Morges (CH)
- Centro Investigación Biomédica en Red Salud Mental (CIBERSAM), Instituto de Biomedicina de Sevilla (IBiS), Departamento de Psiquiatría, Universidad de Sevilla, UGC Salud Mental, Hospital Universitario Virgen del Rocío, Seville, Spain
- Oslo University Hospital (NO)
- Corresponding author
- Alameda, Luis
- ORCID
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2021-04-09
- Volume
- 47
- Issue
- 4
- Pages
- 975-985
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- PMC
- PMC8266673
- OpenAlex
- W3149960801
- Cited by
- 82
- References
- 46
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 17 · 2023: 24 · 2022: 10 · 2021: 5
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
- Locations
- Schizophrenia Bulletin (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Deposito de Investigacion Universidad de Sevilla (University of Seville) (submittedVersion, cc-by-nc-nd)
- IRIS (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Funders
- Swiss National Science Foundation (P2LAP3_171804)
- National Institute for Health Research Biomedical Research Centre
- South London and Maudsley NHS Foundation Trust
- King’s College London (ES/S012567/1)
- South-Eastern Norway Health Authority (#2017060)
- National Alliance for Research on Schizophrenia and Depression (#22388)
- Economic and Social Research Council
- Topics
- Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- childhood adversity, childhood abuse
- MeSH terms
- Adverse Childhood Experiences, Humans, Psychotic Disorders
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