Cognitive Inflexibility Shares Across Schizophrenia and Obsessive–Compulsive Disorder: A Task-Based Functional MRI Study

Chu, Min-yi; Li, Shuai-biao; Zhang, Yao; Wang, Ling-ling; Lv, Qin-yu; Lui, Simon S Y; Wang, Zhen; Yi, Zheng-hui; Wang, Yi; Chan, Raymond C K

doi:10.1093/schbul/sbaf220

Cognitive Inflexibility Shares Across Schizophrenia and Obsessive–Compulsive Disorder: A Task-Based Functional MRI Study

Background and Hypothesis Schizo-obsessive comorbidity (SOC), defined as obsessive–compulsive symptoms (OCS) in schizophrenia (SCZ), is linked to severe psychopathology and poor prognosis. Schizophrenia and obsessive–compulsive disorder (OCD) share cognitive impairments, particularly in inhibitio…