The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Correspondence of DNA Methylation Between Blood and Brain Tissue and Its Application to Schizophrenia Research
Open accessAbstract
Given the difficulty of procuring human brain tissue, a key question in molecular psychiatry concerns the extent to which epigenetic signatures measured in more accessible tissues such as blood can serve as a surrogate marker for the brain. Here, we aimed (1) to investigate the blood-brain correspondence of DNA methylation using a within-subject design and (2) to identify changes in DNA methylation of brain-related biological pathways in schizophrenia.We obtained paired blood and temporal lobe biopsy samples simultaneously from 12 epilepsy patients during neurosurgical treatment. Using the Infinium 450K methylation array we calculated similarity of blood and brain DNA methylation for each individual separately. We applied our findings by performing gene set enrichment analyses (GSEA) of peripheral blood DNA methylation data (Infinium 27K) of 111 schizophrenia patients and 122 healthy controls and included only Cytosine-phosphate-Guanine (CpG) sites that were significantly correlated across tissues.Only 7.9% of CpG sites showed a statistically significant, large correlation between blood and brain tissue, a proportion that although small was significantly greater than predicted by chance. GSEA analysis of schizophrenia data revealed altered methylation profiles in pathways related to precursor metabolites and signaling peptides.Our findings indicate that most DNA methylation markers in peripheral blood do not reliably predict brain DNA methylation status. However, a subset of peripheral data may proxy methylation status of brain tissue. Restricting the analysis to these markers can identify meaningful epigenetic differences in schizophrenia and potentially other brain disorders.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“several studies have reported that most DNA methylation markers detected in the peripheral tissues cannot accurately predict the DNA methylation status of the brain.87”
From Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential (2023) · cites this paper as [87]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Subramanian, A., Tamayo, P., Mootha, V. K., Mukherjee, S., Ebert, B. L., Gillette, M. A., Paulovich, A., Pomeroy, S. L., Golub, T. R., Lander, E. S., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506580102 · Cited by 53,625
Gene Ontology: tool for the unification of biology
Ashburner, M., Ball, C. A., Blake, J. A., Botstein, D., Butler, H., Cherry, J. M., Davis, A. P., Dolinski, K., Dwight, S. S., Eppig, J. T., et al. (2000) · Nature Genetics · doi:10.1038/75556 · Cited by 43,206
Finding the missing heritability of complex diseases
Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature · doi:10.1038/nature08494 · Cited by 8,336
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
McGowan, P. O., Sasaki, A., D'Alessio, A. C., Dymov, S., Labonté, B., Szyf, M., Turecki, G., & Meaney, M. J. (2009) · Nature Neuroscience · doi:10.1038/nn.2270 · Cited by 3,531
DNA methylation landscapes: Provocative insights from epigenomics
Suzuki, M. M., & Bird, A. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2341 · Cited by 3,039
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013) · Nature Genetics · doi:10.1038/ng.2711 · Cited by 2,263
Irizarry, R. A., Ladd-Acosta, C., Wen, B., Wu, Z., Montano, C., Onyango, P., Cui, H., Gabo, K., Rongione, M., Webster, M., et al. (2009) · Nature Genetics · doi:10.1038/ng.298 · Cited by 2,177
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019
Scale for the Assessment of Negative Symptoms
Andreasen, N. C. (1982) · PsycTESTS Dataset · doi:10.1037/t12696-000 · Cited by 1,888
Research works printed but not linked: 2
- First M Spitzer A Gibbon M Williams J. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Nonpatient Edition. New York: New York State Psychiatric Institute; 2002.
- Andreasen NC. Scale for the Assessment of Positive Symptoms. Iowa City: University Iowa Press; 1984.
Cited by
Sorted by citations
Items 201–287 of 287
Does DNA methylation in the fetal brain leave an epigenetic memory in the blood?
Strawn, M., Safranski, T. J., & Behura, S. K. (2023) · Gene · doi:10.1016/j.gene.2023.147788 · Cited by 4
Epigenetic marks in suicide: a review
Ramos-Rosales, D. F., Vázquez-Alaníz, F., Urtiz-Estrada, N., Ramirez-Valles, E. G., Méndez-Hernández, E. M., Salas-Leal, A. C., & Barraza-Salas, M. (2021) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000297 · Cited by 5
Barbu, M. C., Harris, M. A., Shen, X., Stolicyn, A., Green, C., Amador, C., Walker, R. M., Morris, S. W., Adams, M. J., Sandu, A., et al. (2021) · Epigenetics · doi:10.1080/15592294.2021.1997404 · Cited by 4
An investigation into DNA methylation patterns associated with risk preference in older individuals
Smyth, L., Cruise, S., Tang, J.-J., Young, I. S., McGuinness, B., Kee, F., & McKnight, A. (2021) · Epigenetics · doi:10.1080/15592294.2021.1992910 · Cited by 3
Risanti, E. D., Kurniawan, A., Wahyuningsih, L., Dwianingsih, E. K., Rinonce, H. T., & Fachiroh, J. (2018) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v10i2.381 · Cited by 4
Recent Advances in Schizophrenia Genomics and Emerging Clinical Implications
Bigdeli, T. B., & Harvey, P. D. (2025) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2025.01.008 · Cited by 3
Xue, G., Xia, W., Li, L., Zhang, Q., Liu, S., Zhang, J., Hu, W., Zhao, Q., Zhang, W., Luo, C., et al. (2025) · MedComm · doi:10.1002/mco2.70293 · Cited by 3
Stavrum, A.-K., Sirignano, L., Frid, L. M., Frank, J., Foo, J. C., Spíndola, L., Höffler, K. D., Oedegaard, K. J., Haavik, J., Rietschel, M., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03772-y · Cited by 3
Paediatric DNA methylation profile scores: a systematic review and open-source atlas
Schuurmans, I., Defina, S., Hermans, A. P. C., Neumann, A., Suderman, M., Yousefi, P., Felix, J. F., & Cecil, C. A. M. (2026) · EBioMedicine · doi:10.1016/j.ebiom.2026.106300 · Cited by 2
Epigenetic Control in Schizophrenia
D’Addario, C., & Bartolomeo, M. D. (2025) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-75980-2_5 · Cited by 3
Epigenetics and Genetics of Development
Lussier, A. A., Islam, S. A., & Kobor, M. S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804036-2.00007-8 · Cited by 4
Eissenberg, J. C. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823928-5.00035-9 · Cited by 3
Wang, X., Zhao, D., Beeraka, N. M., Spandana, T., Sri, C. D., Nishanth, V. V., Uthaiah, C. A., Leihang, Z., Sugur, K., Liu, J., et al. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220802090446 · Cited by 3
Self-citationSchizophrenia and epigenetics: a comprehensive bibliometric analysis
Huda, A. R. N. E., Asyraf, A. J. M., Norlelawati, A. T., Norain, M. R. S., Salahudin, W. S. W. M., Sofiya, A. N., & Bakrim, N. M. (2023) · Middle East Current Psychiatry · doi:10.1186/s43045-023-00389-z · Cited by 4
Cantarero-Cuenca, A., Gonzalez-Jimenez, A., Martín‐Núñez, G. M., Garrido‐Sánchez, L., Ranea, J. A. G., & Tinahones, F. J. (2024) · Journal of Molecular Medicine · doi:10.1007/s00109-024-02475-z · Cited by 4
Kobow, K., & Khan, N. (2024) · Oxford University Press eBooks · doi:10.1093/med/9780197549469.003.0035 · Cited by 2
Jensen, D., Chen, J., Turner, J. A., Stephen, J. M., Wang, Y., Wilson, T. W., Calhoun, V. D., & Liu, J. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2024.1451150 · Cited by 4
Self-citationCirculating epigenetic signatures classifying brain insulin resistance in humans
Kullmann, S., Singh, A., Sehgal, R., Eichelmann, F., Sandforth, L., Wilms, B., Jähnert, M., Peter, A., Meyhöfer, S., Walther, D., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adv7834 · Cited by 2
From animal to human epigenetics
Berretta, E., Cutuli, D., Laricchiuta, D., & Petrosini, L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819262-7.00002-7 · Cited by 2
Challenges in Analyzing Functional Epigenetic Data in Perspective of Adolescent Psychiatric Health
Manu, D. M., Mwinyi, J., & Schiöth, H. B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105856 · Cited by 2
Whole Blood DNA Methylation Analysis Reveals Epigenetic Changes Associated with ARSACS
Riso, G. D., Naef, V., Damiani, D., Doccini, S., Santorelli, F. M., & Galatolo, D. (2025) · The Cerebellum · doi:10.1007/s12311-025-01791-5 · Cited by 2
Understanding human behavior: What social workers need to know about animal research
Strong, J., & Combs-Orme, T. D. (2018) · Journal of Human Behavior in the Social Environment · doi:10.1080/10911359.2018.1461165 · Cited by 2
Islam, M., & Behura, S. K. (2024) · Genes · doi:10.3390/genes15050604 · Cited by 2
Grigorenko, E. L., & Burenkova, O. V. (2019) · Cambridge University Press eBooks · doi:10.1017/9781108770422.007 · Cited by 2
Innate fear responses are reflected in the blood epigenome of rhesus macaquesPreprint
Bravo-Rivera, H., Lardenoije, R., Merced, D., Mas‐Rivera, A., Ayala, J. E., Gonçalves, J. P., Seligowski, A. V., Jovanović, T., Ressler, K. J., Klengel, T., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.05.369538 · Cited by 2
Wilberforce, A., & Riva, G. V. D. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.20.473375 · Cited by 2
Derakhshan, M., Kessler, N. J., Ishida, M., Demetriou, C., Brucato, N., Moore, G. E., Fall, C. H. D., Chandak, G. R., Ricaut, F., Prentice, A. M., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.17.473110 · Cited by 2
Steroid hormone-mediated epigenetic programming during puberty: uncovering links to depression
DeSouza, E., Kruck, G., & Nagy, C. (2025) · Epigenomics · doi:10.1080/17501911.2025.2554569 · Cited by 1
The future of addiction psychiatry
Arruda, F. S., & Castaldelli-Maia, J. M. (2025) · International Review of Psychiatry · doi:10.1080/09540261.2025.2566211 · Cited by 2
Wyns, A., Hendrix, J., Campenhout, J. V., Buntinx, Y., Xiong, H.-Y., Bruyne, E. D., Godderis, L., Nijs, J., Rice, D. A., Chiang, D. L. C., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27020826 · Cited by 2
Wang, F., Shi, X., Gao, X., Li, D., Guo, Y., Chang, L. Y., & Wang, Y. (2026) · NeuroToxicology · doi:10.1016/j.neuro.2026.103406 · Cited by 1
Zameer, S., Anis, E., Sha, Q., Galvis, M. L. E., Khan, S. Z., Steiner, J. A., Milčiūtė, M., Kerševičiūtė, I., Gabrielaitė, M., Gordevičius, J., et al. (2026) · Clinical Epigenetics · doi:10.1186/s13148-026-02094-0 · Cited by 1
The Methylome of Bipolar Disorder: Evidence from Human and Animal Studies
Walss‐Bass, C., & Fries, G. R. (2019) · RNA technologies · doi:10.1007/978-3-030-14792-1_7 · Cited by 1
Mediating effect of genome-wide DNA methylation on suicidal ideation induced by stressful events
Luca, V. D., Al-Chalabi, N., Chaudhary, Z., Qian, J., Borlido, C., Chintoh, A. F., Gerretsen, P., Graff, A., Remington, G. J., Sanches, M., et al. (2022) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000331 · Cited by 1
Varghese, S. S., Varma, S. V., & Nair, S. V. (2024) · World Journal of Dentistry · doi:10.5005/jp-journals-10015-2353 · Cited by 1
Almodóvar-Payá, C., París-Gómez, I., Latorre-Guardia, M., Guardiola-Ripoll, M., Catalán, R., Arias, B., Penadés, R., & Fatjó‐Vilas, M. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111175 · Cited by 1
Genner, R. M., Meredith, M., Daida, K., Moller, A., Weller, C. A., Ayuketah, A., Jerez, P. Á., Akeson, S., Malik, L., Baker, B., et al. (2026) · npj Dementia · doi:10.1038/s44400-026-00094-8 · Cited by 1
Recent Progress in Functional Genomic Studies of Depression and Suicide
Almeida, D. M., & Turecki, G. (2017) · Current Genetic Medicine Reports · doi:10.1007/s40142-017-0112-y · Cited by 2
Sharp, G. C., Arathimos, R., Reese, S. E., Page, C. M., Felix, J. F., Küpers, L. K., Rifas‐Shiman, S. L., Liu, C., Burrows, K., Zhao, S., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/167791 · Cited by 1
The impact of aversive caregiving on DNA methylation in blood and the prefrontal cortex
Duffy, H. B. D. (2025) · Library, Museums and Press - UDSpace (University of Delaware) · doi:10.58088/kse7-3e24 · Cited by 1
Arkhipov, A. Y., Нурбеков, М. К., & Стрелец, В. Б. (2021) · Research Square · doi:10.21203/rs.3.rs-928057/v1 · Cited by 1
Estudos epigenéticos em dependentes de crack e cocaína: investigação da metilação global do genoma
Camilo, C. (2015) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2015.tde-27102015-112239
Eissenberg, J. C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803239-8.00009-0
Melka, M. G., Castellani, C. A., & Singh, S. M. (2016) · InTech eBooks · doi:10.5772/65905
Toxicoepigenetics and Effects on Life Course Disease Susceptibility
Montrose, L. B., Goodrich, J. M., & Dolinoy, D. C. (2017) · John Wiley & Sons, Inc. eBooks · doi:10.1002/9781119023647.ch13
Epigenetic Studies of Complex Human Disorders and Aging
Jeremian, R. (2018) · TSpace (University of Toronto)
Molecular genetic and epigenetic analysis of osteoarthritis
Rogers, E. L. (2017)
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.00
Vroeë afwykende niepsigotiese gedrag in skisofrenie
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.07
Vatbaarheid vir skisofrenie by 22q11.2-mikroweglatings
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.01
Kliniese kenmerke van Afrikaner-skisofreniepasiënte
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.02
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.08
Spesifieke chromosoomgebiede en/of kandidaatgene geïdentifiseer by skisofrenie
Roos, J. L. (2019) · Genetiese bevindings in ‘n groep Afrikaners met skisofrenie · doi:10.4102/aosis.2019.bk135.03
Qing, L., Xiong, P., Lu, Y., Jiang, H., & Nie, S. (2021) · Research Square · doi:10.21203/rs.3.rs-277493/v1
DNA methylation and cocaine dependence in the human striatum
Vaillancourt, K. (2021) · eScholarship@McGill (McGill) · doi:10.82308/54301
Loureiro, C. M. (2021) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2021.tde-04082021-134444
Molecular regulation of fetal brain development in pigs
Strawn, M. (2021) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/88112
Nicolini, H., Mendoza, A. D. G., & Martínez‐Magaña, J. J. (2022) · Springer eBooks · doi:10.1007/978-3-030-89601-0_4
Roos, J. L. (2019) · doi:10.4102/aosis.2019.bk135.05
Roos, J. L. (2019) · doi:10.4102/aosis.2019.bk135.06
Roos, J. L. (2019) · doi:10.4102/aosis.2019.bk135.04
Brain Derived Neurotrophic Factor (BDNF) Gene in Peripheral Blood Cells of Stable Schizophrenia
Zaifah, A. P. D. N. K., Tokhi, E., Rahim, N. E. H. A., Talib, N. A., & Noor, H. M. (2022) · IIUM Medical Journal Malaysia · doi:10.31436/imjm.v21i1.1840
Can blood at adult age predict epigenetic changes of the brain during fetal stages?Preprint
Strawn, M., Safranski, T. J., & Behura, S. K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.28.518197
Reiner, A., Bakulski, K. M., Fisher, J., Dou, J., Schneper, L. M., Mitchell, C. M., Notterman, D. A., Zawistowski, M., & Ware, E. B. (2022) · medRxiv · doi:10.1101/2022.12.22.22283872
Regulation of fetal brain development in short versus long lived mice
Islam, M. (2022) · MOspace Institutional Repository (University of Missouri) · doi:10.32469/10355/94012
Tomeček, D., Kolenič, M., Bučková, B. R., Tintěra, J., Španiel, F., Horáček, J., & Hlinka, J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.20.613853
Schellhas, L., Luo, M., Felix, J. F., Page, C. M., Bekkhus, M., Munafo, M. R., Zuccolo, L., Havdahl, A., Cecil, C. A. M., & Sharp, G. C. (2025) · medRxiv · doi:10.1101/2025.06.06.25329102
Ran, M., Jin, M., Wang, Z., Zhang, H., Tao, Y., Xu, H., Zou, S., Deng, F., Zhang, H., Tang, X., et al. (2025) · Epigenetics · doi:10.1080/15592294.2025.2560339
Zameer, S., Anis, E., Sha, Q., Galvis, M. L. E., Khan, S. Z., Steiner, J. A., Milčiūtė, M., Kerševičiūtė, I., Gabrielaitė, M., Gordevičius, J., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.25.678349
Adolescent White Matter Maturation Mediates Epigenetic Associations With Cognitive Development
Jensen, D., Chen, J., Turner, J. A., Stephen, J. M., Wang, Y., Wilson, T. W., Calhoun, V. D., & Liu, J. (2025) · Developmental Neurobiology · doi:10.1002/dneu.70000
Self-citationSokolov, A. V., Manu, D.-M., Nordberg, D. O. T., Boström, A. D. E., Jokinen, J., & Schiöth, H. B. (2023) · Figshare · doi:10.6084/m9.figshare.22609666
Gore, S., Meche, B., Shao, D., Ginnett, B., Zhou, K., & Azad, R. K. (2024) · Figshare · doi:10.6084/m9.figshare.26691895
Sokolov, A. V., Manu, D.-M., Nordberg, D. O. T., Boström, A. D. E., Jokinen, J., & Schiöth, H. B. (2023) · Figshare · doi:10.6084/m9.figshare.22609663
DNA methylation as a biomarker of prenatal exposures: current challenges and opportunities
Walkup, R. B., Nangle, M. A., Bergmann, P. E., & Lipinski, R. J. (2026) · Current Zoology · doi:10.1093/eep/dvag006
Multi-omic molecular signatures from peripheral blood samples of patients with mood disorders
Mokhtari, A. (2022) · theses.fr (ABES) · doi:10.70675/6e6b049ez0ae2z40f2za015z47c5c58102d3
Epigenetic Regulation of Hyaluronan-Associated Genes in the Brain: Identifying Key Regulatory Sites
Acevedo, R. E., Walton, E., & Mifsud, K. R. (2026) · Epigenomes · doi:10.3390/epigenomes10020028
Self-citationSaeliw, T., Yuwattana, W., Poolcharoen, C., van Erp, M. L., Kanlayaprasit, S., Vanwong, N., Hu, V. W., Trairatvorakul, P., Chonchaiya, W., & Sarachana, T. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27104161
Dopaminergic gene–epigenetic interactions and impulsivity traits in elite combat sport athletes
Recław, R., Chmielowiec, J., Chmielowiec, K., Masiak, J., & Grzywacz, A. (2026) · Frontiers in Psychology · doi:10.3389/fpsyg.2026.1807306
Trotta, G., Liu, Z., Austin-Zimmerman, I., Spinazzola, E., Sideli, L., Aas, M., Rodríguez, V., Li, Z., Leung, B. M., Li, Q., et al. (2026) · medRxiv · doi:10.64898/2026.06.09.26355257
Schellhas, L., Luo, M., Felix, J. F., Page, C. M., Bekkhus, M., Munafo, M. R., Zuccolo, L., Havdahl, A., Cecil, C. A. M., & Sharp, G. C. (2026) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.70186
Zamora, A. N., Goodrich, J. M., Peterson, K. E., Téllez‐Rojo, M. M., Song, P. X. ‐., Meeker, J. D., Dolinoy, D. C., Torres-Olascoaga, L. A., Cantoral, A., & Jansen, E. C. (2026) · Environmental Research · doi:10.1016/j.envres.2026.125121
Brain and cognitive correlates of FKBP5: methylation patterns in schizophrenia
Latorre-Guardia, M., Almodóvar-Payá, C., París-Gómez, I., Guardiola-Ripoll, M., Canales-Rodríguez, E. J., Fuentes‐Claramonte, P., García‐León, M. Á., Garcia‐Ruiz, B., Sotero-Moreno, A., Guerrero‐Pedraza, A., et al. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111959
Fu, Y., Zhang, Y., Wang, Z., Peng, G., Li, S., Miao, N., & Sun, T. (2026) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.6c00463
Epigenetic processes in depressive and anxiety disorders
Breton, É., Booij, L., & Nemoda, Z. (2026) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19043-8.00032-3
Metadata
- Authors
- Walton, E., Hass, J., Liu, J., Roffman, J. L., Bernardoni, F., Roessner, V., Kirsch, M., Schackert, G., Calhoun, V., & Ehrlich, S.
- Affiliations
- King's College London (GB)
- TransDeN Lab (DE)
- Mind Research Network (US)
- Massachusetts General Hospital (US)
- Center for Regenerative Therapies Dresden (DE)
- Technische Universität Dresden (DE)
- Corresponding author
- Ehrlich, Stefan
- ORCID
- Venue
- Schizophrenia Bulletin
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-06-08
- Volume
- 42
- Issue
- 2
- Pages
- 406-414
- ISSN
- 0586-7614 (ISSN-L)
- 1745-1701
- PMC
- PMC4753587
- OpenAlex
- W2256732880
- Cited by
- 286
- References
- 52
- Citations by year
- 2026: 16 · 2025: 19 · 2024: 14 · 2023: 21 · 2022: 21 · 2021: 39 · 2020: 31 · 2019: 31 · 2018: 36 · 2017: 37 · 2016: 16 · 2015: 5
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Schizophrenia Bulletin (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Explore Bristol Research (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Bristol Research (University of Bristol) (submittedVersion)
- Funders
- Eli Lilly and Company
- National Institutes of Health (5k08mh068540-05)
- National Institute of Mental Health (K08-MH068540)
- National Institute of General Medical Sciences (P20GM103472)
- National Institute of Biomedical Imaging and Bioengineering (R01EB000840, R01EB020407, R01EB005846, R01EB006841)
- National Center for Research Resources (U24RR021992, M01 RR025758-01, P41-RR-14075, U24RR021382, 1U24 RR021382A, UL1RR025758, P41RR014075)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- DNA methylation
- MeSH terms
- Brain, Humans, Schizophrenia, Biomarkers, CpG Islands, DNA Methylation, Epigenesis, Genetic
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
