Cited by 393Schizophrenia research and treatmentPhysical Activity and HealthMental Health and Psychiatry

The DOI matches its Crossref record; 151 of the 151 references it cites were found in a registry or an index.

Exercise Improves Clinical Symptoms, Quality of Life, Global Functioning, and Depression in Schizophrenia: A Systematic Review and Meta-analysis

Open access

Dauwan, Meenakshi, Begemann, Marieke J. H., Heringa, Sophie M., Sommer, Iris E.·2016·Schizophrenia Bulletin

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: Physical exercise may be valuable for patients with schizophrenia spectrum disorders as it may have beneficial effect on clinical symptoms, quality of life and cognition. METHODS: A systematic search was performed using PubMed (Medline), Embase, PsychInfo, and Cochrane Database of Systematic Reviews. Controlled and uncontrolled studies investigating the effect of any type of physical exercise interventions in schizophrenia spectrum disorders were included. Outcome measures were clinical symptoms, quality of life, global functioning, depression or cognition. Meta-analyses were performed using Comprehensive Meta-Analysis software. A random effects model was used to compute overall weighted effect sizes in Hedges' g. RESULTS: Twenty-nine studies were included, examining 1109 patients. Exercise was superior to control conditions in improving total symptom severity (k = 14, n = 719: Hedges' g = .39, P < .001), positive (k = 15, n = 715: Hedges' g = .32, P < .01), negative (k = 18, n = 854: Hedges' g = .49, P < .001), and general (k = 10, n = 475: Hedges' g = .27, P < .05) symptoms, quality of life (k = 11, n = 770: Hedges' g = .55, P < .001), global functioning (k = 5, n = 342: Hedges' g = .32, P < .01), and depressive symptoms (k = 7, n = 337: Hedges' g = .71, P < .001). Yoga, specifically, improved the cognitive subdomain long-term memory (k = 2, n = 184: Hedges' g = .32, P < .05), while exercise in general or in any other form had no effect on cognition. CONCLUSION: Physical exercise is a robust add-on treatment for improving clinical symptoms, quality of life, global functioning, and depressive symptoms in patients with schizophrenia. The effect on cognition is not demonstrated, but may be present for yoga.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1093/schbul/sbv164

Cites

151 of 151 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
The Positive and Negative Syndrome Scale (PANSS) for schizophrenia.
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987) · Schizophrenia Bulletin · doi:10.1093/schbul/13.2.261 · Cited by 21,378
The Brief Psychiatric Rating Scale.
Overall, J. E., & Gorham, D. R. (1962) · Psychological Reports · doi:10.2466/pr0.1962.10.3.799 · Cited by 11,090
Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults
Garber, C. E., Blissmer, B., Deschenes, M. R., Franklin, B. A., Lamonte, M. J., Lee, I.-M., Nieman, D. C., & Swain, D. P. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318213fefb · Cited by 9,319
The Global Assessment Scale: A Procedure for Measuring Overall Severity of Psychiatric Disturbance
Endicott, J. (1976) · Archives of General Psychiatry · doi:10.1001/archpsyc.1976.01770060086012 · Cited by 4,982
Exercise training increases size of hippocampus and improves memory
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., Kim, J. S., Heo, S., Alves, H., White, S. M., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015950108 · Cited by 4,855
Fixed-and random-effects models in meta-analysis.
Hedges, L. V., & Vevea, J. L. (1998) · Psychological Methods · doi:10.1037/1082-989x.3.4.486 · Cited by 2,977

Show all 151 references

Research works printed but not linked: 9

American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disoreders, Fourth Edition(DSM-IV). Washington, DC: American Psychiatric Organisation; 1994.
10.1037//1082-989X.3.4.486 · DOI · Paper page
Hedges L V Olkin I . Statistical Method for Meta-Analysis. Orlando, FL: Academic Press; 2014.
Hu, 2004, Effect of music-sport therapy on the insight and behavioral disturbance in patients with schizophrenia, Chinese J Clin Rehabil, 8, 1626
Malchow, 2011, No effect of aerobic exercise on the amygdala and vermis cerebelli in patients with chronic schizophrenia, Eur Arch Psychiatry Clin Neurosci, 261, S98
2013, Effects of yoga on cognition, glucocorticoid receptor, psychiatric symptoms, weight and metabolic changes in chronic schizophrenic patients, Schizophr Bull, 39, S275
2010, Move the body, work the mind? The impact of body movement on patients with schizophrenia, East Asian Arch Psychiatry, 20, 68
2013, Efficacy of the guidelines for diagnosis and treatment of adolescents with schizophrenia: A comparative study vs usual treatment, Schizophr Bull, 39, S355
2013, Combining cognitive training and exercise to improve cognition and functional outcomes in the early course of schizophrenia: A pilot study, Schizophr Bull, 39, S309

Sorted by citations

Items 101–200 of 393

Altered reward anticipation: Potential explanation for weight gain in schizophrenia?
Grimm, O., Kaiser, S., Plichta, M. M., & Tobler, P. N. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.029 · Cited by 26
“While one recent meta-analysis on humans supports exercise as “a robust add-on treatment” (Dauwan et al., 2015) in schizophrenia, its efficacy is often hard to establish in clinical reality.”
Effects of Exercise on Resilience, Insight and Functionality in Patients with Chronic Schizophrenia in a Psychiatric Nursing Home Setting: A Randomized Controlled Trial
Şenormancı, G., Korkmaz, N., Şenormancı, Ö., Uğur, S., Topsaç, M., & Gültekin, O. (2021) · Issues in Mental Health Nursing · doi:10.1080/01612840.2020.1847221 · Cited by 27
Changes in inflammation are related to depression and amount of aerobic exercise in first episode schizophrenia
Ventura, J., McEwen, S. C., Subotnik, K. L., Hellemann, G., Ghadiali, M., Rahimdel, A., Seo, M. J., Irwin, M. R., & Nuechterlein, K. H. (2020) · Early Intervention in Psychiatry · doi:10.1111/eip.12946 · Cited by 24
Transdiagnostic inflammatory subgroups among psychiatric disorders and their relevance to role functioning: a nested case-control study of the ALSPAC cohort
Byrne, J. F., Healy, C., Mongan, D., Susai, S. R., Zammit, S., Föcking, M., Cannon, M. D., & Cotter, D. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02142-2 · Cited by 26
“These five markers together may confer additional information beyond sTNFR1/2 alone and could be used in the design of targeted trials of infliximab, other immune-regulating therapeutics, or exercise-based interventions [66, 67] for individuals with psychiatric disorders.”
Background
Yoga as part of a package of care versus standard care for schizophrenia
Broderick, J. M., & Vancampfort, D. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012145.pub2 · Cited by 24
Path analysis from physical activity to quality of life among dementia patients: A dual‐path mediating model
Huang, X., Li, B., Yu, F., Zhou, J., Wan, Q., & Chang, H. (2019) · Journal of Advanced Nursing · doi:10.1111/jan.14260 · Cited by 24
Barriers to using physical exercise as an intervention within inpatient mental health settings: A systematic review
MCKenna, C. R., Moyo, B., & Goodwin, J. (2024) · International Journal of Mental Health Nursing · doi:10.1111/inm.13302 · Cited by 23
Behavioural Regulation in Exercise Questionnaire in people with schizophrenia: construct validity of the Portuguese versions
Costa, R., Probst, M., Bastos, T. C. L., Vilhena, E., Seabra, A., & Corredeira, R. (2017) · Disability and Rehabilitation · doi:10.1080/09638288.2017.1342277 · Cited by 27
“improved psychological well-being [1], quality of life [2], and phys-”
Background
Physical activity in secure settings: A scoping review of methods, theory and practise
Rogers, E. N., Kinnafick, F., & Papathomas, A. (2018) · Mental health and physical activity · doi:10.1016/j.mhpa.2018.11.004 · Cited by 22
Important unanswered questions about adult neurogenesis in schizophrenia
Weissleder, C., North, H. F., & Weickert, C. S. (2019) · Current Opinion in Psychiatry · doi:10.1097/yco.0000000000000501 · Cited by 22
Combined aerobic and resistance exercise interventions for individuals with schizophrenia: A systematic review
Martin, H., Beard, S., Clissold, N., Andraos, K., & Currey, L. (2017) · Mental health and physical activity · doi:10.1016/j.mhpa.2017.04.003 · Cited by 25
Treatment of Cognitive Impairment Associated with Schizophrenia Spectrum Disorders: New Evidence, Challenges, and Future Perspectives
Calzavara‐Pinton, I., Nibbio, G., Barlati, S., Bertoni, L., Necchini, N., Zardini, D., Baglioni, A., Paolini, S., Poddighe, L., Bulgari, V., et al. (2024) · Brain Sciences · doi:10.3390/brainsci14080791 · Cited by 23
“Several systematic reviews and meta-analysis have confirmed that PE interventions are also consistently effective in improving CIAS [132,135,136].”
Background
The short and long-term effects of aerobic, strength, or mixed exercise programs on schizophrenia symptomatology
Garcés, L. G., Sánchez‐López, M. I., Cano, S. L., Meliá, Y. C., Marqués-Azcona, D., Biviá-Roig, G., Lisón, J. F., & Peyró-Gregori, L. (2021) · Scientific Reports · doi:10.1038/s41598-021-03761-3 · Cited by 26
Engaging cognitive circuits to promote motor recovery in degenerative disorders. exercise as a learning modality
Jakowec, M. W., Wang, Z., Holschneider, D. P., Beeler, J. A., & Petzinger, G. M. (2016) · Journal of Human Kinetics · doi:10.1515/hukin-2015-0192 · Cited by 21
“In addition to addiction, the benefits of physical training in psychological disorders ranging from depression to schizophrenia have been reported in patients undergoing an exercise regimen (Dauwan et al., 2016; McEwen et al., 2015).”
Yoga versus non-standard care for schizophrenia
Broderick, J. M., Crumlish, N., Waugh, A., & Vancampfort, D. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012052.pub2 · Cited by 23
Yoga as part of a package of care versus non-standard care for schizophrenia
Broderick, J. M., & Vancampfort, D. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012807 · Cited by 20
Evaluation of the benefits of exercise on cognition in major depressive disorder
Greer, T. L., Furman, J. L., & Trivedi, M. H. (2017) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2017.06.002 · Cited by 21
Clinical determinants of physical activity and sedentary behaviour in individuals with schizophrenia
Rashid, N. A. A., Nurjono, M., & Lee, J. (2019) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2019.10.004 · Cited by 26
Parvalbumin Interneuron Activation-Dependent Adult Hippocampal Neurogenesis Is Required for Treadmill Running to Reverse Schizophrenia-Like Phenotypes
Yi, Y., Song, Y., & Lu, Y. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00024 · Cited by 21
Measuring the quality of life of incarcerated individuals
Muller, A. E., & Bukten, A. (2019) · International Journal of Prisoner Health · doi:10.1108/ijph-02-2018-0005 · Cited by 20
Physical exercise and the patient with schizophrenia
Viljoen, M., & Roos, J. L. (2020) · Australian Journal of General Practice · doi:10.31128/ajgp-04-20-5384 · Cited by 21
Locomotor activities as a way of inducing neuroplasticity: insights from conventional approaches and perspectives on eccentric exercises
Clos, P., Lepers, R., & Garnier, Y. M. (2021) · European Journal of Applied Physiology · doi:10.1007/s00421-020-04575-3 · Cited by 19
Physical Activity Can Enhance Life (PACE-Life): results from a 10-week walking intervention for individuals with schizophrenia spectrum disorders
Orleans-Pobee, M., Browne, J., Ludwig, K., Merritt, C., Battaglini, C. L., Jarskog, L. F., Sheeran, P., & Penn, D. L. (2021) · Journal of Mental Health · doi:10.1080/09638237.2021.1875403 · Cited by 24
Physical Activity, Positive and Negative Symptoms of Psychosis, and General Psychopathology among People with Psychotic Disorders: A Meta-Analysis
Swora, E., Boberska, M., Kuliś, E., Knoll, N., Keller, J., & Łuszczyńska, A. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11102719 · Cited by 19
“Regarding positive symptoms, to date, two reviews addressed their relationships with PA among people with schizophrenia [7,18], and their findings were partly contradictory.”
BackgroundMethodResultInfluential
The effects of Baduanjin exercise vs. brisk walking on physical fitness and cognition in middle-aged patients with schizophrenia: A randomized controlled trial
Chen, C.-R., Huang, Y., Lee, Y.-W., Hsieh, H.-H., Lee, Y.-C., & Lin, K. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.983994 · Cited by 19
The Roles of Exercise and Yoga in Ameliorating Depression as a Risk Factor for Cognitive Decline
Mathersul, D. C., & Rosenbaum, S. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/4612953 · Cited by 20
“Several recent systematic reviews and meta-analyses have demonstrated that yoga is effective in ameliorating symptoms of depression across a range of different clinical disorders, includingMDD [45–48], posttraumatic stress disorder (PTSD) [49], stress and anxiety [50], and schizophrenia [51], as well as at-risk sample…”
Background
Effects of aerobic walking on cognitive function in patients with schizophrenia: A randomized controlled trial
Huang, Y., Hung, C., Hsu, S., Lin, P., Lee, Y., Chong, M., Chen, C.-C., Kuo, Y., & Wang, L. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.12.062 · Cited by 24
Assessing validity of retrospective recall of physical activity in individuals with psychosis-like experiences
Andorko, N. D., Rouhakhtar, P. R., Hinkle, C. E., Mittal, V. A., McAllister, M., DeVylder, J., & Schiffman, J. E. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.01.029 · Cited by 19
“Results from intervention studies suggest that physical activity may represent an accessible intervention focus, one that positively impacts both mental and physical well-being (Dauwan et al., 2015; Firth et al., 2015; Firth et al., 2017; Kimhy et al., 2016; Vakhrusheva et al., 2016).”
Background
Using motivational techniques to reduce cardiometabolic risk factors in long term psychiatric inpatients: a naturalistic interventional study
Ringen, P. A., Falk, R. S., Antonsen, B., Faerden, A., Mamen, A., Rognli, E. B., Solberg, D. K., Martinsen, E. W., & Andreassen, O. A. (2018) · BMC Psychiatry · doi:10.1186/s12888-018-1832-6 · Cited by 17
“considered as a more important target for interventions (42) and is possibly easier to improve.”
Background
Effects of aerobic exercise on cardiorespiratory fitness and social functioning in veterans 40 to 65 years old with schizophrenia
Kern, R. S., Reddy, L. F., Cohen, A. N., Young, A. S., & Green, M. F. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113258 · Cited by 18
Diagnosis and treatment depression in schizophrenia
Mosolov, S. N. (2020) · Consortium Psychiatricum · doi:10.17650/2712-7672-2020-1-2-29-42 · Cited by 23
“In addition to biological therapies, attention should be drawn to the proven effectiveness of exercise, including fitness, in reducing depression among patients with schizophrenia, 127 as well as cognitive behavioural therapy 128,129 and psychosocial rehabilitation measures.”
Background
The efficacy and safety of exercise and physical activity on psychosis: A systematic review and meta-analysis
Ziebart, C., Bobos, P., MacDermid, J. C., Furtado, R., Sobczak, D. J., & Doering, M. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.807140 · Cited by 21
“5) 17 (12) Cognitive Performance 4 weeks 4 weeks 24 NR Minimum of 5 years with psychotic disease, stable on medication No comorbid psychotic diagnosis Three weekly sessions each lasting 75 min over 4 weeks, of cognitive training and exercise Three weekly sessions each lasting 75 min over 4 weeks of cognitive training…”
Background
The effect of physical exercise on cognitive function in schizophrenia patients: A GRADE assessed systematic review and meta-analysis of controlled clinical trials
Lak, M., Jafarpour, A., Shahrbaf, M. A., Lak, M., & Dolatshahi, B. (2024) · Schizophrenia Research · doi:10.1016/j.schres.2024.07.020 · Cited by 19
Definition, assessment and treatment of cognitive impairment associated with schizophrenia: expert opinion and practical recommendations
Vita, A., Barlati, S., Cavallaro, R., Mucci, A., Riva, M. A., Rocca, P., Rossi, A., & Galderisi, S. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1451832 · Cited by 28
Heterogeneous trajectories in schizophrenia: insights from neurodevelopment and neuroprogression models
Reckziegel, R. D. F. X., Czepielewski, L. S., Hasse-Sousa, M., Martins, D. S., de Britto, M. J. S., Lapa, C. D. O., Schwartzhaupt, A. W., & Gama, C. S. (2021) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2020-1670 · Cited by 24
Work out by Walking
Browne, J., Penn, D. L., Battaglini, C. L., & Ludwig, K. (2016) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000556 · Cited by 20
“Research examining the health impact of exercise interventions for individuals with SSDs is promising (Dauwan et al., 2016; Firth et al., 2015; Rosenbaum et al., 2014).”
BackgroundResult
Promoting quality of life and recovery in adults with mental health issues using exercise and nutrition intervention
Whybird, G., Nott, Z. E., Savage, E., Korman, N., Suetani, S., Hielscher, E., Vilic, G., Tillston, S., Patterson, S., & Chapman, J. (2020) · International Journal of Mental Health · doi:10.1080/00207411.2020.1854023 · Cited by 21
Actividad física, naturaleza y bienestar mental: una revisión sistemática
Ballester-Martínez, O., Baños, R., & Navarro‐Mateu, F. (2022) · Cuadernos de Psicología del Deporte · doi:10.6018/cpd.465781 · Cited by 45
Rethinking Schizophrenia and Depression Comorbidity as One Psychiatric Disorder Entity: Evidence From Mouse Model
Zhou, C., Kong, D., Zhu, X., Wu, W., Xue, R., Li, G., Xu, Y. J., Liu, S., Tian, H., & Zhuo, C. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00115 · Cited by 19
Targeting physical health in schizophrenia: Results from the Physical Activity Can Enhance Life (PACE-Life) 24-week open trial
Browne, J., Battaglini, C. L., Jarskog, L. F., Sheeran, P., Abrantes, A. M., McDermott, J., Elliott, T., González, O., & Penn, D. L. (2021) · Mental health and physical activity · doi:10.1016/j.mhpa.2021.100393 · Cited by 22
Effects of mild‐intensity physical exercise on neurocognition in inpatients with schizophrenia: A pilot randomized controlled trial
Kurebayashi, Y., Mori, K., & Otaki, J. (2021) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12896 · Cited by 19
Associations between physical activity and motivation, competence, functioning, and apathy in inhabitants with mental illness from a rural municipality: a cross-sectional study
Farholm, A., Sørensen, M., Halvari, H., & Hynnekleiv, T. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1528-3 · Cited by 26
Efficacy of Mindfulness-Based Interventions for Negative Symptoms in Patients Diagnosed with Schizophrenia: a Meta-analysis
Chai, J., Xiao, X., An, N., Liu, F., Liu, S., Hu, N., Yang, Y., Cui, Y., & Li, Y. (2022) · Mindfulness · doi:10.1007/s12671-022-01942-3 · Cited by 17
“, 2014) and considerably influence patient quality of life (Dauwan et al., 2016).”
Background
Dopamine, Psychosis, and Symptom Fluctuation: A Narrative Review
Novak, G., & Seeman, M. (2022) · Healthcare · doi:10.3390/healthcare10091713 · Cited by 17
“One potential way schizophrenia patients have found to improve their social comfort is by becoming more active because exercise is associated with im-proved social skills [127], while sedentary behavior ap-pears to increase the frequency of delusions [109].”
Background
Virtual group-based walking intervention for persons with schizophrenia: A pilot randomized controlled trial
Browne, J., Battaglini, C. L., Jarskog, L. F., Sheeran, P., Abrantes, A. M., Elliott, T., González, O., & Penn, D. L. (2023) · Mental health and physical activity · doi:10.1016/j.mhpa.2023.100515 · Cited by 20
Implications of Physical Exercise on Episodic Memory and Anxiety: The Role of the Serotonergic System
Illesca-Matus, R., Ardiles, N. M., Muñoz, F., & Moya, P. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241411372 · Cited by 19
“Additionally, voluntary chronic exercise improved psychiatric symptoms and the quality of life in patients with schizophrenia [19,20].”
Background
A Longitudinal Examination of Real-World Sedentary Behavior in Adults with Schizophrenia-Spectrum Disorders in a Clinical Trial of Combined Oxytocin and Cognitive Behavioral Social Skills Training
Browne, J., Harvey, P. D., Buchanan, R., Kelly, D. L., Strauss, G. P., Gold, J. M., Holden, J. L., & Granholm, E. L. (2022) · Behavioral Sciences · doi:10.3390/bs12030060 · Cited by 15
Effects of yoga on clinical symptoms, quality of life and social functioning in patients with schizophrenia: A systematic review and meta-analysis
Yin, J., Sun, Y., Zhu, Y., Alifujiang, H., Wang, Y., An, S., Huang, H., Fu, X., Deng, H., & Chen, Y. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.103959 · Cited by 15
Physical activity and quality of life/subjective well-being in people with disabilities: A look backwards and a way forwards
Ginis, K. A. M. (2025) · Psychology of sport and exercise · doi:10.1016/j.psychsport.2025.102916 · Cited by 19
Autonomous motivation and quality of life as predictors of physical activity in patients with schizophrenia
Costa, R., Bastos, T. C. L., Probst, M., Seabra, A., Vilhena, E., & Corredeira, R. (2018) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2018.1435821 · Cited by 22
Enriched environment as a nonpharmacological neuroprotective strategy
Vaquero-Rodríguez, A., Ortuzar, N., Lafuente, J. V., & Bengoetxea, H. (2023) · Experimental Biology and Medicine · doi:10.1177/15353702231171915 · Cited by 14
Predictors of adherence to exercise interventions in people with schizophrenia
Schwaiger, R., Maurus, I., Lembeck, M., Papazova, I., Greska, D., Muenz, S., Sykorova, E. B., Thieme, C. E., Vogel, B. O., Mohnke, S., et al. (2024) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-024-01789-w · Cited by 15
“Exercise interventions reveal beneficial effects on overall cognitive performance [13–16], positive and negative symptoms [14, 17–22], depressive symptoms [14], levels of functioning [14, 19, 20], and quality of life [14, 17–19] among people with schizophrenia.”
Background
The Physical Health Care Fidelity Scale: Psychometric Properties
Ruud, T., Høifødt, T. S., Hendrick, D. C., Drake, R. E., Høye, A., Landers, M., Heiervang, K. S., & Bond, G. R. (2020) · Administration and Policy in Mental Health and Mental Health Services Research · doi:10.1007/s10488-020-01019-0 · Cited by 15
A web-based adapted physical activity program (e-APA) versus health education program (e-HE) in patients with schizophrenia and healthy volunteers: study protocol for a randomized controlled trial (PEPSY V@Si)
Tréhout, M., Leroux, E., Bigot, L., Jego, S., Leconte, P., Reboursière, E., Morello, R., Chapon, P.-A., Herbinet, A., Quarck, G., et al. (2020) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-020-01140-z · Cited by 15
Management of constipation in patients with schizophrenia—a case study and review of literature
Sarangi, A., Armin, S., Vargas, A., Chu, V., Fain, K., & Nelson, J. E. (2021) · Middle East Current Psychiatry · doi:10.1186/s43045-021-00097-6 · Cited by 14
“stress relief, and exercise regime can have a profound effect on the frequency and severity of symptoms and reduce the likelihood of developing comorbidities that add to the disease burden [7, 12, 13].”
Background
Associations between aerobic fitness, negative symptoms, cognitive deficits and brain structure in schizophrenia—a cross-sectional study
Maurus, I., Röll, L., Keeser, D., Karali, T., Papazov, B., Hasan, A., Schmitt, A., Papazova, I., Lembeck, M., Hirjak, D., et al. (2022) · Schizophrenia · doi:10.1038/s41537-022-00269-1 · Cited by 15
Using Cognitive Neuroscience to Improve Mental Health Treatment: A Comprehensive Review
Wojtalik, J. A., Eack, S. M., Smith, M. J., & Keshavan, M. S. (2018) · Journal of the Society for Social Work and Research · doi:10.1086/697566 · Cited by 17
The effectiveness of structured exercise programmes on psychological and physiological outcomes for patients with psychotic disorders: A systematic review and meta-analysis
Fox‐Harding, C., Tompsett, C., Sanders, R. H., & Cobley, S. P. (2018) · International Journal of Sport and Exercise Psychology · doi:10.1080/1612197x.2018.1519838 · Cited by 14
“ment, Dauwan et al. (2015) examined the effect of structured and unstructured types of exercise intervention on outcomes of symptom severity (e.g. PANSS scores), cognition and quality of life. Dauwan et al. (2015) identified studies investigating yoga – forms of physical activity explicitly omitted from this present s…”
BackgroundResultInfluential
Identification of Risk Factors to Predict the Occurrences of Relapses in Individuals with Schizophrenia Spectrum Disorder in Iran
Davarinejad, O., Majd, T. M., Golmohammadi, F., Mohammadi, P., Radmehr, F., Alikhani, M., Motaei, T., Moradinazar, M., Brühl, A. B., Bahmani, D. S., et al. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18020546 · Cited by 14
Die Bedeutung von körperlicher Aktivität für die psychische Gesundheit
Imboden, C., Claussen, M. C., Seifritz, E., & Gerber, M. (2022) · Praxis · doi:10.1024/1661-8157/a003831 · Cited by 16
Effects of Exercise on Structural and Functional Brain Patterns in Schizophrenia—Data From a Multicenter Randomized-Controlled Study
Roell, L., Keeser, D., Papazov, B., Lembeck, M., Papazova, I., Greska, D., Muenz, S., Schneider-Axmann, T., Sykorova, E. B., Thieme, C. E., et al. (2023) · Schizophrenia Bulletin · doi:10.1093/schbul/sbad113 · Cited by 15
Lifestyle intervention based on exercise and behavioural counselling and its effect on physical and psychological health in outpatients with schizophrenia spectrum disorders. An exploratory, pragmatic randomized clinical trial
Fernández-Abascal, B., Suárez‐Pinilla, M., Cobo-Corrales, C., Crespo‐Facorro, B., & Suárez‐Pinilla, P. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.09.036 · Cited by 14
Treadmill Exercise Enhances Post-Stroke Functional Recovery in Mice via the CX3CL1/CX3CR1 Signaling Pathway
Ge, Y., Dou, X., Chen, P., Chen, J., Dai, M., Yao, S., & Lin, Y. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04287-1 · Cited by 13
“Numerous studies demonstrate the considerable protective effects of exercise on human diseases such as neurological disorders[9, 10], cardiovascular diseases[11, 12], as well as metabolic, inflammatory, and oncological conditions[13].”
Effects of aerobic exercise on hippocampal formation volume in people with schizophrenia – a systematic review and meta-analysis with original data from a randomized-controlled trial
Roell, L., Fischer, T., Keeser, D., Papazov, B., Lembeck, M., Papazova, I., Greska, D., Muenz, S., Schneider-Axmann, T., Sykorova, E. B., et al. (2024) · Psychological Medicine · doi:10.1017/s0033291724001867 · Cited by 16
“…evidence appears promising, demonstrating that exercise treatments improve both cognitive functioning (Dauwan et al., 2016; Fernández-Abascal et al., 2021; Korman et al., 2023) and daily life functioning (Dauwan et al., 2016; Fernández-Abascal et al., 2021; Korman et al., 2023) in schizophrenia.”
Influential
Which behavioral regulations predict physical activity and sedentary behavior in people with mental illness?
Chapman, J., Korman, N., Malacova, E., Robertson, C. V., Arnautovska, U., Siskind, D. J., Suetani, S., Stubbs, B., & Vancampfort, D. (2024) · Psychological Medicine · doi:10.1017/s0033291724001879 · Cited by 13
“…(Stubbs et al., 2016; Vancampfort et al., 2016c), and efficacy in reducing metabolic risk factors and improving symptoms of mental illnesses (Dauwan, Begemann, Heringa, & Sommer, 2015; Schuch et al., 2016); however, little is known about how to facilitate long-term healthy lifestyle…”
Motor impairments in early onset schizophrenia
Byrial, P., Nyboe, L., Thomsen, P. H., & Clausen, L. (2021) · Early Intervention in Psychiatry · doi:10.1111/eip.13185 · Cited by 13
Association between aerobic fitness and the functional connectome in patients with schizophrenia
Roell, L., Maurus, I., Keeser, D., Karali, T., Papazov, B., Hasan, A., Schmitt, A., Papazova, I., Lembeck, M., Hirjak, D., et al. (2022) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-022-01411-x · Cited by 13
“In people with schizophrenia, different kinds of exercise treatments show small to medium beneficial effects on positive [22–26] and negative symptom severity [22–25, 27, 28], depressive symptoms [24, 29], several cognitive domains [25, 26, 29, 30], quality of life [24, 29] and global functioning [24, 26, 31].”
Background
Association between altered physical activity and neurocognitive function among people with schizophrenia: A minimum 6-months' follow-up study
Kurebayashi, Y., & Otaki, J. (2017) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2017.06.001 · Cited by 13
The effects of clinical illness severity and physical activity on health-related quality of life in schizophrenia
Ang, M. S., Nurjono, M., & Lee, J. (2019) · Quality of Life Research · doi:10.1007/s11136-019-02126-8 · Cited by 15
Resistance training in patients with schizophrenia: Concept and proof of principle trial
Maurus, I., Mantel, C., Keller-Varady, K., Schmitt, A., Lembeck, M., Röh, A., Papazova, I., Falkai, P., Schneider-Axmann, T., Hasan, A., et al. (2019) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2019.09.015 · Cited by 13
Vision-Related Quality of Life and Its Sociodemographic Correlates Among Individuals With Visual Impairments
Panigrahi, A., Rao, G. N., & Konar, A. K. (2021) · Journal of Visual Impairment & Blindness · doi:10.1177/0145482x211028938 · Cited by 13
Improving depressive symptoms in patients with schizophrenia using bilateral bipolar-nonbalanced prefrontal tDCS: Results from a double-blind sham-controlled trial
Lisoni, J., Nibbio, G., Baldacci, G., Zucchetti, A., Cicale, A., Zardini, D., Miotto, P., Deste, G., Barlati, S., & Vita, A. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.050 · Cited by 12
Effect of a nurse‐led intervention program on the physical health and quality of life of individuals with severe mental illness
İnce, S. Ç., & Günüşen, N. P. (2021) · Perspectives In Psychiatric Care · doi:10.1111/ppc.12745 · Cited by 12
A narrative review of treatment interventions to improve cognitive performance in schizophrenia, with an emphasis on at-risk and early course stages
Mayeli, A., Clancy, K. J., Sonnenschein, S. F., Sarpal, D. K., & Ferrarelli, F. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114926 · Cited by 12
Correlations between physical activity and neurocognitive domain functions in patients with schizophrenia: a cross-sectional study
Kurebayashi, Y., & Otaki, J. (2017) · BMC Psychiatry · doi:10.1186/s12888-016-1176-z · Cited by 11
“However, most previous studies have only investigated the correlation between physical activity and memory or general cognitive function [13].”
Background
Exercise and Antipsychotic Drugs
Mary, V. S. (2017) · Journal of Patient Care · doi:10.4172/2573-4598.1000114 · Cited by 11
“Exercise is one factor that has been shown to temporarily enhance treatment effects in schizophrenia [2-8].”
Background
The Influence of Continuous Exercising on Chronotropic Incompetence in Multi-Episode Schizophrenia
Herbsleb, M., Keller-Varady, K., Wobrock, T., Hasan, A., Schmitt, A., Falkai, P., Gabriel, H. H. W., Bär, K., & Malchow, B. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00090 · Cited by 14
“Additionally to somatic health benefits, aerobic exercise positively impacts core features of the disease itself like cognitive deficits (15–17) and negative symptoms (18).”
Background
Focus on Brain Health to Improve Care, Treatment, and Rehabilitation in Forensic Psychiatry
Andiné, P., & Bergman, H. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00840 · Cited by 11
“In patients with schizophrenia, aerobic exercise has positive effects on psychotic symptoms, cognitive function, general functional outcomes and quality of life (43, 44).”
Background
Lessons Learned From a Physical Activity Intervention in Psychiatric Treatment: Patient, Staff, and Leader Perspectives
Sørensen, M., Bentzen, M., & Farholm, A. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00087 · Cited by 25
L’activité physique chez les patients atteints de schizophrénie : de la neurobiologie aux bénéfices cliniques
Tréhout, M., & Dollfus, S. (2018) · L Encéphale · doi:10.1016/j.encep.2018.05.005 · Cited by 17
The impact of endurance training and table soccer on brain metabolites in schizophrenia
Rauchmann, B., Ghaseminejad, F., Keeser, D., Keller-Varady, K., Schneider-Axmann, T., Takahashi, S., Karali, T., Helms, G., Dechent, P., Maurus, I., et al. (2019) · Brain Imaging and Behavior · doi:10.1007/s11682-019-00198-1 · Cited by 11
Functioning in schizophrenia: a Delphi study covering the perspective of physiotherapists
Nuño, L., Barrios, M., Vancampfort, D., Rojo, E., Gómez‐Benito, J., & Guilera, G. (2020) · Disability and Rehabilitation · doi:10.1080/09638288.2020.1748729 · Cited by 11
Interventions for negative symptoms in schizophrenia: efficacy and clinical interpretability in a meta-analysis of 451 randomized controlled trials
Damiani, S., Stefanelli, R., Fortea, L., D'Imperio, A., Calò, M., Casarini, F., Crippa, A., Esposito, C. M., Leggi, R., Marika, O., et al. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03543-1 · Cited by 12
“Lastly, lifestyle interventions such as aerobic or mind-body exercise also demonstrated moderate ef ﬁ cacy across trials [29 – 31].”
Is It Possible to Combine Non-Invasive Brain Stimulation and Evidence-Based Psychosocial Interventions in Schizophrenia? A Critical Review
Lisoni, J., Nibbio, G., Baglioni, A., Dini, S., Manera, B., Maccari, A., Altieri, L., Calzavara‐Pinton, I., Zucchetti, A., Deste, G., et al. (2024) · Brain Sciences · doi:10.3390/brainsci14111067 · Cited by 11
The use of physical exercise in forensic psychiatric care in Sweden: a nationwide survey
Bergman, H., Nilsson, T., Andiné, P., Degl’Innocenti, A., Thomeé, R., & Gutke, A. (2021) · Journal of Mental Health · doi:10.1080/09638237.2021.1875406 · Cited by 10
“The use of exercise to treat psychiatric symptoms and cognitive deficits in severe mental illness is still a relatively novel concept, but the evidence base has grown stronger in recent years (Dauwan et al., 2016; Firth et al., 2017; Stubbs et al., 2018).”
BackgroundInfluential
Occupational Outcomes of a Physical Activity Intervention for Post-Secondary Student Mental Health
Nesbitt, A. E., Collins, K. J., Nalder, E. J., & Sabiston, C. M. (2021) · Canadian Journal of Occupational Therapy · doi:10.1177/00084174211021708 · Cited by 12
The Impact of Regular Physical Exercise on Psychopathology, Cognition, and Quality of Life in Patients Diagnosed with Schizophrenia: A Scoping Review
Vila-Barrios, L., Carballeira, E., Varela-Sanz, A., Iglesias‐Soler, E., & Dopico-Calvo, X. (2023) · Behavioral Sciences · doi:10.3390/bs13120959 · Cited by 10
“However, there is controversy about which exercise modalities have positive effects on QoL, cognition, and psychopathological symptoms [34,35].”
Background
Pilot Study of an Exercise Intervention for Depressive Symptoms and Associated Cognitive-Behavioral Factors in Young Adults With Major Depression
Nasstasia, Y., Baker, A., Halpin, S. A., Lewin, T. J., Hides, L. M., Kelly, B. J., & Callister, R. (2016) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000000611 · Cited by 10
“Recent meta-analyses have highlighted potential benefits of physical exercise for mental health conditions (Dauwan et al., 2016; Schuch et al., 2016).”
Background
Could physical exercise be an effective treatment for adults with borderline personality disorder?
St‐Amour, S., Cailhol, L., Ruocco, A. C., & Bernard, P. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113625 · Cited by 10
Exercise training complementary to specialised early intervention in patients with first-episode psychosis: a feasibility randomised trial
Midtgaard, J., Schnor, H., Bjerre, E. D., Jespersen, T., Jelsøe, N., Frølund, N., Seier, S., Rønbøg, J. W., Nordsborg, N. B., & Ebdrup, B. H. (2021) · Pilot and Feasibility Studies · doi:10.1186/s40814-021-00900-5 · Cited by 11
Knowledge domain and trends in treatment-resistant schizophrenia (TRS) research based on CiteSpace bibliometrics analysis
Cai, H., Du, R., Zhang, J., Wang, X. Y., Li, W., Yang, K., & Wang, Z. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1478625 · Cited by 9
Integrative Medicine and Mood, Emotions and Mental Health
Shah, A. K., Becicka, R., Talen, M. R., Edberg, D., & Namboodiri, S. (2017) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2017.02.003 · Cited by 9
Nonpharmacological treatment of dyscognition in schizophrenia: effects of aerobic exercise
Maurus, I., Röh, A., Falkai, P., Malchow, B., Schmitt, A., & Hasan, A. (2019) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2019.21.3/aschmitt · Cited by 9
Cognition and Exercise
Gaalema, D. E., Mahoney, K., & Ballon, J. S. (2021) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0000000000000644 · Cited by 10
Physical Activity as Treatment for Depression in Recreation Therapy: Transitioning from Research to Practice
Nagata, S., McCormick, B. P., & Austin, D. R. (2020) · Therapeutic Recreation Journal · doi:10.18666/trj-2020-v54-i1-9745 · Cited by 12
Yoga as part of a package of care versus non-standard care for schizophrenia
Broderick, J. M., & Vancampfort, D. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012807.pub2 · Cited by 9
Relationship between Sensory Profile and Self-Perceived Quality of Life in People with Schizophrenia: An Exploratory Study
Sanchis-Asensi, A., Triviño-Juárez, J. M., Sanchis-Almiñana, H., & Ayuso, D. M. R. (2022) · Occupational Therapy in Mental Health · doi:10.1080/0164212x.2022.2125925 · Cited by 8
Brief Theory-based Intervention to Improve Physical Activity in Men with Psychosis and Obesity: A Feasibility Study
Romain, A. J., Cadet, R., & Baillot, A. (2020) · Science of Nursing and Health Practices · doi:10.31770/2561-7516.1084 · Cited by 8
“Indeed, several studies showed its beneficial effects on several outcomes including weight management, cardiovascular health, functioning, or psychotic symptoms (Dauwan et al., 2016; Firth et al., 2017; Ohi et al., 2018; Romain et al., 2019; Rosenbaum et al., 2015).”
BackgroundResult
Strategies for Psychiatric Rehabilitation and their Cognitive Outcomes in Schizophrenia: Review of Last Five-year Studies
Rampino, A., Falcone, R. M., Giannuzzi, A., Masellis, R., Antonucci, L. A., & Torretta, S. (2021) · Clinical Practice and Epidemiology in Mental Health · doi:10.2174/1745017902117010031 · Cited by 8
Effects of Pilates-Based Exercises on Functional Capacity and Mental Health in Individuals with Schizophrenia: A Pilot Study
Akbaş, E., Erdem, E. U., Guneş, E., Özkan, T. D., & Kınıklı, G. İ. (2021) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2021.1929613 · Cited by 8

Authors: Dauwan, M., Begemann, M. J. H., Heringa, S. M., & Sommer, I. E.
Affiliations: University Medical Center Utrecht (NL)
Corresponding author: Dauwan, Meenakshi
ORCID: Dauwan, Meenakshi
Begemann, Marieke J. H.
Heringa, Sophie M.
Sommer, Iris E.
Venue: Schizophrenia Bulletin
Publisher: Oxford University Press (OUP)
Published: 2015-11-07
Volume: 42
Issue: 3
Pages: 588-599
ISSN: 0586-7614 (ISSN-L)
1745-1701
DOI: 10.1093/schbul/sbv164
PMC: PMC4838091
OpenAlex: W2176833440
Cited by: 393
References: 151
Citations by year: 2026: 21 · 2025: 34 · 2024: 43 · 2023: 42 · 2022: 44 · 2021: 40 · 2020: 40 · 2019: 51 · 2018: 28 · 2017: 37 · 2016: 11 · 2015: 1
FWCI: 3.53
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: other-oa
Locations: Schizophrenia Bulletin (publishedVersion, other-oa)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Pure Amsterdam UMC (publishedVersion, other-oa)
Utrecht University Repository (Utrecht University) (submittedVersion)
Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
HighWire Press Open Archive (submittedVersion)
Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion)
University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords: physical activity, schizophrenia
MeSH terms: Depression, Exercise Therapy, Humans, Quality of Life, Schizophrenia, Outcome Assessment, Health Care, Cognitive Dysfunction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Exercise Improves Clinical Symptoms, Quality of Life, Global Functioning, and Depression in Schizophrenia: A Systematic Review and Meta-analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks