The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Lysosome‐related organelles
Abstract
Lysosomes are membrane‐bound cytoplasmic organelles involved in intracellular protein degradation. They contain an assortment of soluble acid‐dependent hydrolases and a set of highly glycosylated integral membrane proteins. Most of the properties of lysosomes are shared with a group of cell type‐specific compartments referred to as ‘lysosome‐related organelles’, which include melanosomes, lytic granules, MHC class II compartments, platelet‐dense granules, basophil granules, azurophil granules, and Drosophila pigment granules. In addition to lysosomal proteins, these organelles contain cell type‐specific components that are responsible for their specialized functions. Abnormalities in both lysosomes and lysosome‐related organelles have been observed in human genetic diseases such as the Chediak‐Higashi and Hermansky‐Pudlak syndromes, further demonstrating the close relationship between these organelles. Identification of genes mutated in these human diseases, as well as in mouse and Drosophila pigmentation mutants, is beginning to shed light on the molecular machinery involved in the biogenesis of lysosomes and lysosome‐related organelles.—Dell'Angelica, E. C., Mullins, C., Caplan, S., Bonifacino, J. S. Lysosome‐related organelles. FASEB J. 14, 1265–1278 (2000)
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ohkuma, S., & Poole, B. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.7.3327 · Cited by 2,174
Kornfeld, S., & Mellman, I. (1989) · Annual Review of Cell Biology · doi:10.1146/annurev.cb.05.110189.002411 · Cited by 1,580
ENDOCYTOSIS AND MOLECULAR SORTING
Mellman, I. (1996) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.12.1.575 · Cited by 1,533
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes.
Peters, P. J., Borst, J., Oorschot, V, Fukuda, M., Krähenbühl, O., Tschopp, J., Slot, J. W., & Geuze, H. J. (1991) · The Journal of experimental medicine · doi:10.1084/jem.173.5.1099 · Cited by 713
Dell’Angelica, E. C., Shotelersuk, V., Aguilar, R. C., Gahl, W. A., & Bonifacino, J. S. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80170-7 · Cited by 672
Self-citationPeters, P. J., Neefjes, J. J., Oorschot, V., Ploegh, H. L., & Geuze, H. J. (1991) · Nature · doi:10.1038/349669a0 · Cited by 657
The Emerging Role of CTLA-4 as an Immune Attenuator
Thompson, C. B., & Allison, J. P. (1997) · Immunity · doi:10.1016/s1074-7613(00)80366-0 · Cited by 634
Mammalian Tyrosinase Catalyzes Three Reactions in the Biosynthesis of Melanin
Körner, A., & Pawelek, J. (1982) · Science · doi:10.1126/science.6810464 · Cited by 587
A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase.
Tsukamoto, K., Jackson, I. J., Urabe, K., Montague, P. M., & Hearing, V. J. (1992) · The EMBO Journal · doi:10.1002/j.1460-2075.1992.tb05082.x · Cited by 562
Identification of the homologous beige and Chediak–Higashi syndrome genes
Barbosa, M. D. F. S., Nguyen, Q. A., Tchernev, V. T., Ashley, J. A., Detter, J. C., Blaydes, S. M., Brandt, S. J., Chotai, D., Hodgman, C., Solari, R. C. E., et al. (1996) · Nature · doi:10.1038/382262a0 · Cited by 552
Research works printed but not linked: 15
- 10.1007/s109-1998-8099-y · doi:10.1007/s109-1998-8099-y
- 10.1016/S0021-9258(17)42738-4 · doi:10.1016/s0021-9258(17)42738-4
- 10.1083/jcb.102.2.516 · doi:10.1083/jcb.102.2.516
- Bonifacino J. S., 1989, Internal ization and recycling to serotonin‐containing granules of the 80K integral membrane protein exposed on the surface of secreting rat basophilic leukaemia cells, J. Cell Sci., 92, 701, 10.1242/jcs.92.4.701 · doi:10.1242/jcs.92.4.701
- 10.1182/blood.V91.3.1044 · doi:10.1182/blood.v91.3.1044
- 10.1002/jlb.64.1.72 · doi:10.1002/jlb.64.1.72
- Rendu F., 1983, Evidence that abnormal platelet functions in human Chediak‐Higashi syndrome are the result of a lack of dense bodies, Am. J. Pathol., 111, 307
- 10.1002/ajmg.1320030112 · doi:10.1002/ajmg.1320030112
- 10.2500/108854192778816933 · doi:10.2500/108854192778816933
- Pastural E., 1999, Griscelli disease maps to chromosome 15q and is associated with mutations in the Myosin‐Va gene (Correction), Nat Genet, 23, 373, 10.1038/15565 · doi:10.1038/15565
- 10.1086/301611 · doi:10.1086/301611
- 10.1006/geno.1997.4764 · doi:10.1006/geno.1997.4764
- Frank D. W., 1999, Differential sorting of tyrosinase and lysosomal proteins in melanized cells, Mol. Biol. Cell, 10, 224a
- Masson D., 1990, Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T‐cells is dependent on pH, Biochemistry, 25, 11229, 10.1021/bi00503a011 · doi:10.1021/bi00503a011
- Copier J., 1996, Targeting signal and subcellular compartments involved in the intracellular trafficking of HLA‐DMB, J. Immunol., 157, 1017, 10.4049/jimmunol.157.3.1017 · doi:10.4049/jimmunol.157.3.1017
Cited by
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function
Saftig, P., & Klumperman, J. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2745 · Cited by 1,648
Induction of Lymphocyte Apoptosis by Tumor Cell Secretion of FasL-bearing Microvesicles
Andreola, G., Rivoltini, L., Castelli, C., Huber, V., Perego, P., Deho, P., Squarcina, P., Accornero, P., Lozupone, F., Lugini, L., et al. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011624 · Cited by 774
Mechanisms and functions of lysosome positioning
Pu, J., Guardia, C. M., Keren-Kaplan, T., & Bonifacino, J. S. (2016) · Journal of Cell Science · doi:10.1242/jcs.196287 · Cited by 570
Self-citationRaposo, G., Tenza, D., Murphy, D. M., Berson, J. F., & Marks, M. S. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.4.809 · Cited by 451
Pmel17 initiates premelanosome morphogenesis within multivesicular bodies
Berson, J. F., Harper, D. C., Tenza, D., Raposo, G., & Marks, M. S. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.11.3451 · Cited by 326
Metadata
- Authors
- Dell'Angelica, E. C., Mullins, C., Caplan, S., & Bonifacino, J. S.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2000-07
- Volume
- 14
- Issue
- 10
- Pages
- 1265-1278
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W1939081758
- Cited by
- 503
- References
- 114
- FWCI
- 10.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Funders
- National Research Council
- Human Frontier Science Program
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Lysosome‐related organelles. https://app.cochat.ai/papers/10.1096/fasebj.14.10.1265
- The paper
- Dell'Angelica, E. C., Mullins, C., Caplan, S., & Bonifacino, J. S. (2000). Lysosome‐related organelles. The FASEB Journal. https://doi.org/10.1096/fasebj.14.10.1265
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
