The DOI matches its Crossref record.
Oxidants, inflammation, and anti‐inflammatory drugs
Abstract
Species such as superoxide radical (O 2 − ), hydrogen peroxide (H 2 O 2 ), hydroxyl radical ( · OH), and hypochlorous acid (HOC1) can be formed in vivo, e.g., by activated phagocytic cells. Generation of · OH from H 2 O 2 in vivo usually involves iron‐dependent reactions. Good evidence exists for increased generation of oxidants in vivo in patients with active rheumatoid disease, but the contribution of these oxidants to the disease process is still uncertain. The likelihood that anti‐inflammatory drugs used in the treatment of arthritis could act by scavenging oxidants or preventing their formation is discussed.— H alliwell , B.; H oult , J. R.; B lake , D. R. Oxidants, inflammation, and anti‐inflammatory drugs. FASEB J. 2: 2867‐2873; 1988.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
[1] Role of free radicals and catalytic metal ions in human disease: An overview
Halliwell, B., & Gutteridge, J. M. C. (1990) · Methods in Enzymology · doi:10.1016/0076-6879(90)86093-b · Cited by 4,994
Self-citationFree Radicals as Mediators of Tissue Injury and Disease
Kehrer, J. P. (1993) · Critical Reviews in Toxicology · doi:10.3109/10408449309104073 · Cited by 1,455
Morrow, J. D., Harris, T. M., & Jackson Roberts, L. (1990) · Analytical Biochemistry · doi:10.1016/0003-2697(90)90002-q · Cited by 477
Degradative Action of Reactive Oxygen Species on Hyaluronan
Šoltés, L., Mendichi, R., Kogan, G., Schiller, J., Stankovská, M., & Arnhold, J. (2006) · Biomacromolecules · doi:10.1021/bm050867v · Cited by 329
Acute hyperglycemia and oxidative stress: Direct cause and effect?
Choi, S.-W., Benzie, I. F. F., Ma, S.-W., Strain, J. J., & Hannigan, B. M. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.005 · Cited by 149
Metadata
- Authors
- Halliwell, B., Hoult, J. R., & Blake, D. R.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 1988-10
- Volume
- 2
- Issue
- 13
- Pages
- 2867-2873
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W1494675041
- Cited by
- 267
- References
- 0
- FWCI
- 10.02
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Oxidants, inflammation, and anti‐inflammatory drugs. https://app.cochat.ai/papers/10.1096/fasebj.2.13.2844616
- The paper
- Halliwell, B., Hoult, J. R., & Blake, D. R. (1988). Oxidants, inflammation, and anti‐inflammatory drugs. The FASEB Journal. https://doi.org/10.1096/fasebj.2.13.2844616
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
