Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

Adlam, Victoria J., Harrison, Joanne C., Porteous, Carolyn M., James, Andrew M., Smith, Robin A. J., Murphy, Michael P., Sammut, Ivan A.·2005·The FASEB Journal

DOI 10.1096/fj.05-3718com

Cited by (617)

Items 101–200 of 617

Mitochondria-Targeted Antioxidants: A Step towards Disease Treatment
Qian Jiang, Jie Yin, Jiashun Chen, Xiaokang Ma, Miaomiao Wu, Gang Liu, Yao Kang, Bie Tan, Yulong Yin · 2020 · Oxidative Medicine and Cellular Longevity
Protection against renal ischemia–reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ
Dare, Anna J., Bolton, Eleanor A., Pettigrew, Gavin J., Bradley, J. Andrew, Saeb-Parsy, Kourosh, Murphy, Michael P. · 2015 · Redox Biology
Regulation of VEGF-induced endothelial cell migration by mitochondrial reactive oxygen species
Youxue Wang, Qun Sophia Zang, Zijuan Liu, Qian Wu, David L. Maass, Genevieve Dulan, Philip W. Shaul, Lisa M. Melito, Doug E. Frantz, Jessica A. Kilgore et al. · 2011 · American Journal of Physiology-Cell Physiology
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine
Carlotta Giorgi, Chiara Agnoletto, Angela Bononi, Massimo Bonora, Elena De Marchi, Saverio Marchi, Sonia Missiroli, Simone Patergnani, Federica Poletti, Alessandro Rimessi et al. · 2011 · Mitochondrion
Molecular Characterization of Reactive Oxygen Species in Myocardial Ischemia-Reperfusion Injury
Tingyang Zhou, Chia‐Chen Chuang, Li Zuo · 2015 · BioMed Research International
Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II
Dong, Lan-Feng, Jameson, Victoria J.A., Tilly, David, Cerny, Jiri, Mahdavian, Elahe, Marín-Hernández, Alvaro, Hernández-Esquivel, Luz, Rodríguez-Enríquez, Sara, Stursa, Jan, Witting, Paul K. et al. · 2011 · Journal of Biological Chemistry
Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases
Ryan M. Whitaker, Daniel G. Corum, Craig Beeson, Rick G. Schnellmann · 2015 · The Annual Review of Pharmacology and Toxicology
Rapid and extensive uptake and activation of hydrophobic triphenylphosphonium cations within cells
Ross, Meredith F., Prime, Tracy A., Abakumova, Irina, James, Andrew M., Porteous, Carolyn M., Smith, Robin A. J., Murphy, Michael P. · 2008 · Biochemical Journal
The Aging Heart: Figure 1.
Ying Ann Chiao, Peter S. Rabinovitch · 2015 · Cold Spring Harbor Perspectives in Medicine
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice
Rodriguez-Cuenca, Sergio, Cochemé, Helena M., Logan, Angela, Abakumova, Irina, Prime, Tracy A., Rose, Claudia, Vidal-Puig, Antonio, Smith, Anthony C., Rubinsztein, David C., Fearnley, Ian M. et al. · 2010 · Free Radical Biology and Medicine
Prevention of diabetic nephropathy in Ins2+/−AkitaJ mice by the mitochondria-targeted therapy MitoQ
Chacko, Balu K., Reily, Colin, Srivastava, Anup, Johnson, Michelle S., Ye, Yaozu, Ulasova, Elena, Agarwal, Anupam, Zinn, Kurt R., Murphy, Michael P., Kalyanaraman, Balaraman et al. · 2010 · Biochemical Journal
Mitochondrial quality control as a key determinant of cell survival
Lucia Sedlackova, Viktor I. Korolchuk · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Nikole J. Byrne, Namakkal Soorappan Rajasekaran, E. Dale Abel, Heiko Bugger · 2021 · Free Radical Biology and Medicine
Mitochondria as a target in treatment
Marie‐Céline Frantz, Peter Wipf · 2010 · Environmental and Molecular Mutagenesis
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)
L. E. Bakeeva, Igor Valentinovich Barskov, Maxim V. Egorov, Н. К. Исаев, Valeri I. Kapelko, A.V. Kazachenko, V.I. Kirpatovsky, Stanislav V. Kozlovsky, Vladimir L. Lakomkin, S. B. Levina et al. · 2008 · Biochemistry (Moscow)
Mitochondria and cardioprotection
Fabio Di Lisa, Marcella Canton, Roberta Menabò, Nina Kaludercic, Paolo Bernardi · 2007 · Heart Failure Reviews
Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria
Swati Biswas, Namita Sudhir Dodwadkar, Aleksandr Piroyan, Vladimir P. Torchilin · 2012 · Biomaterials
Multifunctional nanoplatforms for subcellular delivery of drugs in cancer therapy
Xing Guo, Wei Xiao, Zi Chen, Xiaobin Zhang, Guang Yang, Shaobing Zhou · 2019 · Progress in Materials Science
Cardiopulmonary Bypass and Oxidative Stress
Mustafa Zakkar, Gustavo Antonio Guida, M.Saadeh Suleiman, Gianni D. Angelini · 2015 · Oxidative Medicine and Cellular Longevity
MicroRNA-210 Controls Mitochondrial Metabolism and Protects Heart Function in Myocardial Infarction
Rui Song, Chiranjib Dasgupta, Cassidy Mulder, Li Zhang · 2022 · Circulation
MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload
Rogério Faustino Ribeiro Júnior, Erinne Rose Dabkowski, Kadambari Chandra Shekar, Kelly A. O ́Connell, Peter A. Hecker, Michael P. Murphy · 2018 · Free Radical Biology and Medicine
Inhibition of Mitochondrial Permeability Transition Pore Opening by Ischemic Preconditioning Is Probably Mediated by Reduction of Oxidative Stress Rather Than Mitochondrial Protein Phosphorylation
Samantha J. Clarke, Игорь Германович Халиулин, Manika Das, Joanne E. Parker, Kate J. Heesom, Andrew P. Halestrap · 2008 · Circulation Research
Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases
Simone Patergnani, Esmaa Bouhamida, Sara Leo, Paolo Pinton, Alessandro Rimessi · 2021 · Biomedicines
Targeted nanoparticles in mitochondrial medicine
Rakesh Pathak, Nagesh Kolishetti, Shanta Dhar · 2014 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
Mitochondrial dysfunction in cardiac ischemia–reperfusion injury: ROS from complex I, without inhibition
Andrew J. Tompkins, Lindsay S. Burwell, Stanley B. Digerness, Corinne Zaragoza, William L. Holman, Paul S. Brookes · 2005 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Understanding and preventing mitochondrial oxidative damage
Michael P. Murphy · 2016 · Biochemical Society Transactions
Cellular Redox Homeostasis
Kristell Le Gal, Edward E. Schmidt, Volkan I. Sayin · 2021 · Antioxidants
The role of succinate and ROS in reperfusion injury – A critical appraisal
Tatiana Andrienko, Philippe Pasdois, Gonçalo C. Pereira, Matthew J. Ovens, Andrew P. Halestrap · 2017 · Journal of Molecular and Cellular Cardiology
Redox Control of the Survival of Healthy and Diseased Cells
Yuxing Zhang, Yanzhi Du, Weidong Le, Kankan Wang, Nelly Kieffer, Ji Zhang · 2011 · Antioxidants and Redox Signaling
Mitochondrial Oxidative Damage in Aging and Alzheimer′s Disease: Implications for Mitochondrially Targeted Antioxidant Therapeutics
P. Hemachandra Reddy · 2006 · BioMed Research International
Mitochondria in vascular disease
Emma Yu, John R. Mercer, Martin R. Bennett · 2012 · Cardiovascular Research
Mitochondrial dysfunction in cardiac aging
Autumn Tocchi, Ellen K. Quarles, Nathan Basisty, Lemuel Gitari, Peter S. Rabinovitch · 2015 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Exercise‐induced protection against myocardial apoptosis and necrosis: MnSOD, calcium‐handling proteins, and calpain
Joel P. French, Karyn L. Hamilton, John C. Quindry, Youngil Lee, Patrick A. Upchurch, Scott K. Powers · 2008 · The FASEB Journal
MitoQ administration prevents endotoxin-induced cardiac dysfunction
Gerald S. Supinski, Michael P. Murphy, Leigh Ann Callahan · 2009 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease
María E. Solesio, Tracy A. Prime, Angela Logan, Michael P. Murphy, María del Mar Arroyo Jiménez, Joaquı́n Jordán, María Francisca Galindo · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
The key role of mitochondria in Alzheimer's disease
Paula Isabel Moreira, Sandra M. Cardoso, Maria S. Santos, Catarina Resende Oliveira · 2006 · Journal of Alzheimer s Disease
MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism
Mengyuan Cen, Wei Ouyang, Wanying Zhang, Liping Yang, Xiuhui Lin, Min Dai, Huiqun Hu, Huifang Tang, Hongyun Liu, Jingyan Xia et al. · 2021 · Redox Biology
The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster
Tapiwanashe Magwere, Melanie Jane West, Kumars Riyahi, Michael P. Murphy, Robin A.J. Smith, Linda Partridge · 2006 · Mechanisms of Ageing and Development
Mechanisms of Exercise-Induced Cardioprotection
Scott K. Powers, Ashley J. Smuder, Andreas N. Kavazis, John C. Quindry · 2014 · Physiology
Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis
Helen F. Galley · 2010 · Critical Care
Mitochondrial ROS Induces Cardiac Inflammation via a Pathway through mtDNA Damage in a Pneumonia-Related Sepsis Model
Xiao Yao, Deborah Carlson, Yuxiao Sun, Lisha Ma, Steven E. Wolf, Joseph P. Minei, Qun Sophia Zang · 2015 · PLoS ONE
SOD1 and MitoTEMPO partially prevent mitochondrial permeability transition pore opening, necrosis, and mitochondrial apoptosis after ATP depletion recovery
Huan Liang, Filip Sedlić, Zeljko J. Bosnjak, Vani Nilakantan · 2010 · Free Radical Biology and Medicine
Molecular Vehicles for Mitochondrial Chemical Biology and Drug Delivery
Sae Rin Jean, David V. Tulumello, Simon Wisnovsky, Eric K. Lei, Mark P. Pereira, Shana O. Kelley · 2014 · ACS Chemical Biology
Early myopathy in Duchenne muscular dystrophy is associated with elevated mitochondrial H 2 O 2 emission during impaired oxidative phosphorylation
Meghan C. Hughes, Sofhia Verena Ramos, Patrick C. Turnbull, Irena A. Rebalka, Andrew W. Cao, Cynthia M. F. Monaco, Nina E. Varah, Brittany A. Edgett, Jason S. Huber, Peyman Tadi et al. · 2019 · Journal of Cachexia Sarcopenia and Muscle
Myocardial energetics in heart failure
Alexander Georg Nickel, Joachim Löffler, Christoph Maack · 2013 · Basic Research in Cardiology
Cardioprotection and mitochondrial S-nitrosation: Effects of S-nitroso-2-mercaptopropionyl glycine (SNO-MPG) in cardiac ischemia–reperfusion injury
Sergiy M. Nadtochiy, Lindsay S. Burwell, Paul S. Brookes · 2007 · Journal of Molecular and Cellular Cardiology
Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice
Kah Yong Goh, Li He, Jiajia Song, Miki Jinno, Aaron J. Rogers, Palaniappan Sethu, Ganesh V. Halade, Namakkal Soorappan Rajasekaran, Xiaoguang Liu, Sumanth D. Prabhu et al. · 2019 · Redox Biology
Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases
Hegde, Muralidhar L., Mantha, Anil K., Hazra, Tapas K., Bhakat, Kishor K., Mitra, Sankar, Szczesny, Bartosz · 2012 · Mechanisms of Ageing and Development
Targeting oxidative stress for the treatment of ischemic stroke: Upstream and downstream therapeutic strategies
Shaohua Yang, Wenjun Li · 2016 · Brain Circulation
Mitochondrial bioenergetics and cardiolipin alterations in myocardial ischemia-reperfusion injury: implications for pharmacological cardioprotection
Giuseppe Paradies, Valeria Paradies, Francesca Maria Ruggiero, Giuseppe Petrosillo · 2018 · American Journal of Physiology-Heart and Circulatory Physiology
Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection
Gerd Heusch, Ioanna Andreadou, Robert Bell, Edoardo Bertero, Hans Erik Bøtker, Sean M. Davidson, James M. Downey, Philip Eaton, Péter Ferdinandy, Bernard John Gersh et al. · 2023 · Redox Biology
Mitochondrial targeting of quinones: Therapeutic implications
Helena M. Cochemé, Geoffrey F. Kelso, Andrew M. James, Meredith F. Ross, Ján Trnka, Thabo Mahendiran, Jorge Asin-Cayuela, Frances H. Blaikie, Abdul‐Rahman B. Manas, Carolyn M. Porteous et al. · 2007 · Mitochondrion
Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing
Jan Gruber, Sheng Fong, Ce-Belle Chen, Sia Lee Yoong, Giorgia Pastorin, Sebastian Schaffer, Irwin Kee-Mun Cheah, Barry B. Halliwell · 2012 · Biotechnology Advances
Reduction in mitochondrial iron alleviates cardiac damage during injury
Hsiang‐Chun Chang, Rongxue Wu, Meng Shang, Tatsuya Sato, Chunlei Chen, Jason Solomon Shapiro, Ting Liu, Anita Thakur, Konrad Teodor Sawicki, Sathyamangla V Naga Prasad et al. · 2016 · EMBO Molecular Medicine
A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome
Anna J Dare, Anthony R.J. Phillips, Anthony J. Hickey, Anubhav Mittal, Benjamin P. T. Loveday, Nichola M. Thompson, John Albert Windsor · 2009 · Free Radical Biology and Medicine
Mitochondria-Targeted Antioxidants, an Innovative Class of Antioxidant Compounds for Neurodegenerative Diseases: Perspectives and Limitations
Matteo Fields, Annalisa Marcuzzi, Arianna Gonelli, Claudio Celeghini, Natalia Maximova, Erika Rimondi · 2023 · International Journal of Molecular Sciences
Cardiac Dysfunction and Oxidative Stress in the Metabolic Syndrome: an Update on Antioxidant Therapies
Olesya L. Ilkun, Sihem Boudina · 2013 · Current Pharmaceutical Design
A Review on Oxidative Stress, Diabetic Complications, and the Roles of Honey Polyphenols
Visweswara Rao Pasupuleti, Chandra Sekhar Arigela, Siew Hua Gan, Sirajudeen Kuttulebbai Naina Mohamed Salam, Kumara Thevan Krishnan, Nurhanan Abdul Rahman, Mohammad Saffree Jeffree · 2020 · Oxidative Medicine and Cellular Longevity
Mitochondrial Reactive Oxygen Species and Risk of Atherosclerosis
Maarten Hulsmans, Els Van Dooren, Paul Holvoet · 2012 · Current Atherosclerosis Reports
Inhibition of the mPTP and Lipid Peroxidation Is Additively Protective Against I/R Injury
Arielys Mendoza, Pooja Patel, Dexter J. Robichaux, Daniel Ramirez, Jason M. Karch · 2024 · Circulation Research
Nanotechnology inspired tools for mitochondrial dysfunction related diseases
Ru M. Wen, Bhabatosh Banik, Rakesh Pathak, Anil Kumar, Nagesh Kolishetti, Shanta Dhar · 2016 · Advanced Drug Delivery Reviews
Mitochondrial Superoxide Production and Nuclear Factor Erythroid 2-Related Factor 2 Activation in p75 Neurotrophin Receptor-Induced Motor Neuron Apoptosis
Mariana Pehar, Marcelo R. Vargas, Kristine M. Robinson, Patricia Cassina, Pablo Díaz‐Amarilla, Tory M. Hagen, Rafael Radí, Luis Barbeito, Joseph S. Beckman · 2007 · Journal of Neuroscience
Mitochondria‐Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury
Aleksandra Kezić, Ivan Spasojević, Višnja Ležaić, Milica Bajčetić · 2016 · Oxidative Medicine and Cellular Longevity
Protective effect of melatonin against mitochondrial dysfunction associated with cardiac ischemiareperfusion: role of cardiolipin
Giuseppe Petrosillo, Nicola Di Venosa, Marilva Pistolese, Giacoma Casanova, Edy Tiravanti, Giuseppe Colantuono, Antonio Federici, Giuseppe Paradies, Francesca Maria Ruggiero · 2006 · The FASEB Journal
The mitochondrial permeability transition pore in AD 2016: An update
Lucia Biasutto, Michele Azzolini, Ildikò Szabó, Mario Zoratti · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Acrolein is a mitochondrial toxin: Effects on respiratory function and enzyme activities in isolated rat liver mitochondria
Li Sun, Cheng Yu Luo, Jiangang Long, Dongzhi Wei, Jiankang Liu · 2006 · Mitochondrion
The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia
Philippe Pasdois, Joanne E. Parker, Elinor J. Griffiths, Andrew P. Halestrap · 2011 · Biochemical Journal
Reactive oxygen species-mediated cardiac-reperfusion injury: Mechanisms and therapies
Fereshteh Bagheri, Vahid Khori, Ali Mohammad Alizadeh, Solmaz Khalighfard, Saeed Khodayari, Hamid Khodayari · 2016 · Life Sciences
Accumulation of lipophilic dications by mitochondria and cells
Meredith F. Ross, Tatiana Da Ros, Frances H. Blaikie, Tracy A. Prime, Carolyn M. Porteous, Inna I. Severina, Vladimir P. Skulachev, Henrik Grum Kjaergaard, Robin A.J. Smith, Michael P. Murphy · 2006 · Biochemical Journal
Riding the tiger – physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix
Martin D. Brand · 2020 · Critical Reviews in Biochemistry and Molecular Biology
Gestational Diabetes Mellitus and Maternal Immune Dysregulation: What We Know So Far
Colm J. McElwain, Fergus P. McCarthy, Cathal McCarthy · 2021 · International Journal of Molecular Sciences
The Role of Mitochondrial Reactive Oxygen Species in Cardiovascular Injury and Protective Strategies
Danina Mirela Muntean, Adrian Sturza, Maria D. Dănilă, Claudia Borza, Oana Duicu, Cristian Mornoş · 2016 · Oxidative Medicine and Cellular Longevity
Mitochondria: a new therapeutic target in chronic kidney disease
Simona Granata, Alessandra Dalla Gassa, Paola Tomei, Antonio Lupo, Gianluigi Zaza · 2015 · Nutrition & Metabolism
Endothelial mitochondria and heart disease
Sean M. Davidson · 2010 · Cardiovascular Research
Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: Implications for mitochondria-specific therapies and probes
Porteous, Carolyn M., Logan, Angela, Evans, Cameron, Ledgerwood, Elizabeth C., Menon, David K., Aigbirhio, Franklin, Smith, Robin A.J., Murphy, Michael P. · 2010 · Biochimica et Biophysica Acta (BBA) - General Subjects
Evolving Concepts of Oxidative Stress and Reactive Oxygen Species in Cardiovascular Disease
Kai Chen, John F. Keaney · 2012 · Current Atherosclerosis Reports
Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions☆
Valerian E. Kagan, Peter Wipf, Detcho A. Stoyanovsky, Joel S. Greenberger, Grigory G. Borisenko, Natalia A. Belikova, Naveena V. K. Yanamala, Alejandro Khalil Samhan-Arias, Muhammad A. Tungekar, Jianfei Jiang · 2009 · Advanced Drug Delivery Reviews
Mitochondrial calcium and reactive oxygen species in cardiovascular disease
Elizabeth Murphy, Julia C. Liu · 2022 · Cardiovascular Research
The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model
Dare, Anna J., Logan, Angela, Prime, Tracy A., Rogatti, Sebastian, Goddard, Martin, Bolton, Eleanor M., Bradley, J. Andrew, Pettigrew, Gavin J., Murphy, Michael P., Saeb-Parsy, Kourosh · 2015 · The Journal of Heart and Lung Transplantation
Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis
Chacko, Balu K., Srivastava, Anup, Johnson, Michelle S., Benavides, Gloria A., Chang, Mi Jung, Ye, Yaozu, Jhala, Nirag, Murphy, Michael P., Kalyanaraman, Balaraman, Darley-Usmar, Victor M. · 2011 · Hepatology
MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis
Peizhong Mao, Maria Mańczak, Ulziibat P. Shirendeb, P. Hemachandra Reddy · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Exercise Preconditioning of the Myocardium
Andreas N. Kavazis · 2009 · Sports Medicine
MitoQ protects dopaminergic neurons in a 6-OHDA induced PD model by enhancing Mfn2-dependent mitochondrial fusion via activation of PGC-1α
Xi Ye, Dayun Feng, Kai Xiong Tao, Ronglin Wang, Yajun Shi, Huaizhou Qin, Michael P. Murphy, Qian Yang, Gang Zhao · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
A review of myocardial ischaemia/reperfusion injury: Pathophysiology, experimental models, biomarkers, genetics and pharmacological treatment
Mehmet Günata, Hakan Parlakpınar · 2020 · Cell Biochemistry and Function
Mitochondrial dysfunction in cardiovascular disease: Current status of translational research/clinical and therapeutic implications
Antonis S. Manolis, Antonis A. Manolis, Theodora A. Manolis, Naomi E. Apostolaki, Evdoxia J. Apostolopoulos, Helen Melita, Niki Katsiki · 2020 · Medicinal Research Reviews
Mitochondrial DNA-Associated Leigh Syndrome and NARP
David Ross Thorburn, Joyeeta Rahman, Shamima Rahman · 2014 · University of Washington, Seattle eBooks
A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation
Xiaoyu Lin, Caroline A. David, Jennifer B. Donnelly, Mike R Michaelides, Navdeep S. Chandel, Xiaoli Huang, Usha Warrior, Frank D. Weinberg, Kathryn V. Tormos, Stephen W. Fesik et al. · 2008 · Proceedings of the National Academy of Sciences
Mitochondria‐Targeted Antioxidants in the Treatment of Disease
Robin A.J. Smith, Victoria J. Adlam, Frances H. Blaikie, Abdul‐Rahman B. Manas, Carolyn M. Porteous, Andrew M. James, Meredith F. Ross, Angela Logan, Helena M. Cochemé, Ján Trnka et al. · 2008 · Annals of the New York Academy of Sciences
Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin
István Lekli, Gergő Vilmos Szabó, Béla Juhász, Samarjit Das, Manika Das, Edit Varga, Levente Szendrei, Rudolf Gesztelyi, Judit Váradi, István Bak et al. · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
Mitochondria and reperfusion injury of the heart—A holey death but not beyond salvation
Andrew P. Halestrap · 2009 · Journal of Bioenergetics and Biomembranes
Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View
Roberta Filograna, Mariano Beltramini, Luigi Bubacco, Marco Bisaglia · 2016 · Current Neuropharmacology
Diabetic Retinopathy, Superoxide Damage and Antioxidants
Julia Matzenbacher dos Santos, Ghulam Mohammad, Qing Peter Wild Zhong, Renu A. Kowluru · 2011 · Current Pharmaceutical Biotechnology
Hemigramicidin–TEMPO conjugates: Novel mitochondria-targeted anti-oxidants
Mitchell P. Fink, Carlos A. Macias, Jingbo Xiao, Yulia Y. Tyurina, Jianfei Jiang, Natalia A. Belikova, Russell L. Delude, Joel S. Greenberger, Valerian E. Kagan, Peter Wipf · 2007 · Biochemical Pharmacology
Protective efficacy of mitochondrial targeted antioxidant MitoQ against dichlorvos induced oxidative stress and cell death in rat brain
Willayat Yousuf Wani, Satish Gudup, Aditya Sunkaria, Amanjit Bal, Parvinder Pal Singh, Ramesh J. L. Kandimalla, Deep Raj Sharma, Kiran Dip Gill · 2011 · Neuropharmacology
Targeting the Mitochondrial Permeability Transition Pore to Prevent Age‐Associated Cell Damage and Neurodegeneration
Andrew C. Kent, Khairat Bahgat Youssef El Baradie, Mark W. Hamrick · 2021 · Oxidative Medicine and Cellular Longevity
The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients
Irene Escribano‐López, Noelia Díaz‐Morales, Susana Rovira‐Llopis, A Marañón, Samuel Orden, Ángeles Álvarez, Celia Bañuls, Milagros Rocha, Michael P. Murphy, Antonio Hernández‐Mijares et al. · 2016 · Redox Biology
Melatonin inhibits free radical‐mediated mitochondrial‐dependent hepatocyte apoptosis and liver damage induced during malarial infection
Mithu Guha, Pallab Maity, Vinay Choubey, Kalyan Mitra, Russel Joseph Reiter, Uday Bandyopadhyay · 2007 · Journal of Pineal Research
Mechanism and Treatment Related to Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy
Xingping Qin, Jing Cheng, Yi Zhong, Omer Kamal Mahgoub, Farhana Akter, Yanqin Fan, Mohammed S. Aldughaim, Qiurong Xie, Lingxia Qin, Lijuan Gu et al. · 2019 · Frontiers in Molecular Neuroscience
Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model
Qun Sophia Zang, Hesham A. Sadek, David L. Maass, Bobbie Martinez, Lisha Ma, Jessica A. Kilgore, Noelle Sevilir Williams, Doug E. Frantz, Jane G. Wigginton, Fiemu E. Nwariaku et al. · 2012 · American Journal of Physiology-Heart and Circulatory Physiology
Moving Forwards by Blocking Back-Flow
Victoria R. Pell, Edward T. Chouchani, Michael P. Murphy, Paul S. Brookes, Thomas Krieg · 2016 · Circulation Research