Uncoupling protein-2 controls proliferation by promoting fatty acid oxidation and limiting glycolysis-derived pyruvate utilization

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing.

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Mitochondria, Oxidants, and Aging

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Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

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Growth factor regulation of autophagy and cell survival in the absence of apoptosis

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Superoxide activates mitochondrial uncoupling proteins

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Cooperation and Competition in the Evolution of ATP-Producing Pathways

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Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

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Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

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Reactive oxygen species in tumor progression

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Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, β-cell dysfunction, and type 2 diabetes.

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A role for uncoupling protein‐2 as a regulator of mitochondrial hydrogen peroxide generation

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Uncoupling Protein 2, in Vivo Distribution, Induction upon Oxidative Stress, and Evidence for Translational Regulation

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Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction

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Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction

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Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side

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Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate?

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Protective Role of Uncoupling Protein 2 in Atherosclerosis

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Uncoupling Protein 2: A Possible Link Between Fatty Acid Excess and Impaired Glucose-Induced Insulin Secretion?

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Phosphatidylinositol 3-Kinase-dependent Modulation of Carnitine Palmitoyltransferase 1A Expression Regulates Lipid Metabolism during Hematopoietic Cell Growth

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MAP‐LC3, a promising autophagosomal marker, is processed during the differentiation and recovery of podocytes from PAN nephrosis

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Oxidative Stress and Tumour Cell Proliferation

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Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages

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No Evidence for a Basal, Retinoic, or Superoxide-induced Uncoupling Activity of the Uncoupling Protein 2 Present in Spleen or Lung Mitochondria

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Up-Regulation of UCP-2 Gene Expression by PPAR Agonists in Preadipose and Adipose Cells

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Persistent Nuclear Factor-κB Activation in Ucp2-/- Mice Leads to Enhanced Nitric Oxide and Inflammatory Cytokine Production

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Physiological Levels of Mammalian Uncoupling Protein 2 Do Not Uncouple Yeast Mitochondria

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Hydrogen Peroxide in Relation to Proliferation and Apoptosis in BHK-21 Hamster Fibroblasts

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Glutamine stimulates translation of uncoupling protein 2mRNA

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Nutrient control of macroautophagy in mammalian cells

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Uncoupling Protein 2 Has Protective Function during Experimental Autoimmune Encephalomyelitis

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Enhanced colon tumor induction in uncoupling protein-2 deficient mice is associated with NF-κB activation and oxidative stress

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Effects of fatty acids on uncoupling protein‐2 expression in the rat heart

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Bone Marrow Transplantation Reveals the in Vivo Expression of the Mitochondrial Uncoupling Protein 2 in Immune and Nonimmune Cells during Inflammation

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Overexpression of Uncoupling Protein 2 in THP1 Monocytes Inhibits β 2 Integrin-Mediated Firm Adhesion and Transendothelial Migration

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Stable expression of functional mitochondrial uncoupling protein in Chinese hamster ovary cells.

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Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial activity in the presence of glucose

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Uncoupling protein 3 and fatty acid metabolism

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Dietary Fatty Acids Up-Regulate the Expression of UCP2 in 3T3-L1 Preadipocytes

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Does the Oxidative/Glycolytic Ratio Determine Proliferation or Death in Immune Recognition?

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Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

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Mitochondrial uncoupling, ROS generation and cardioprotection

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UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

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Microglial UCP2 mediates inflammation and obesity induced by high-fat feeding

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Microbes & neurodevelopment – Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala

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The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation

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UCP2, not a physiologically relevant uncoupler but a glucose sparing switch impacting ROS production and glucose sensing

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Determinants of muscle carnosine content

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Fatty Acid Flippase Activity of UCP2 Is Essential for Its Proton Transport in Mitochondria

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Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release

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Catabolic Pathways of Soluble Degradation Products from Plant Biomass

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4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart

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Effects of 2[5(4-chlorphenyl)pentyl]oxirane-2- carboxylate on fatty acid synthesis and fatty acid oxidation in isolated rat hepatocytes

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Control of glycolysis in pathologic cardiac hypertrophy

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Regulation of acetyl-CoA carboxylase in the control of fatty acid synthesis and fatty acid oxidation

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