RAGE‐dependent signaling in microglia contributes to neuroinflammation, Aβ accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
Fang, Fang, Lue, Lih-Fen, Yan, Shiqiang, Xu, Hongwei, Luddy, John S., Chen, Doris, Walker, Douglas G., Stern, David M., Yan, Shifang, Schmidt, Ann Marie, Chen, John X., Yan, Shirley ShiDu·2010·The FASEB Journal
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Items 101–200 of 335
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- Amyloid β-interacting partners in Alzheimer's disease: From accomplices to possible therapeutic targetsHan, Sun-Ho, Park, Jong-Chan, Mook-Jung, Inhee · 2016 · Progress in Neurobiology
- Assessment of Advanced Glycation End Products and Receptors and the Risk of DementiaJinluan Chen, Sanne S. Mooldijk, Silvan Licher, Komal Waqas, M. Kamran Ikram, André Gerardus Uitterlinden, MCarola Zillikens, M. Arfan Ikram · 2021 · JAMA Network Open
- Receptor for Advanced Glycation End Products and its Inflammatory Ligands are Upregulated in Amyotrophic Lateral SclerosisJuranek, Judyta K., Daffu, Gurdip K., Wojtkiewicz, Joanna, Lacomis, David, Kofler, Julia, Schmidt, Ann Marie · 2015 · Frontiers in Cellular Neuroscience
- Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer’s DiseaseCátia S. Janota, Cynthia Ann Lemere, María Alexandra Brito · 2015 · Molecular Neurobiology
- Obesity and Diabetes Mediated Chronic Inflammation: A Potential Biomarker in Alzheimer’s DiseaseMd Shahjalal Hossain Khan, Vijay K. Hegde · 2020 · Journal of Personalized Medicine
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- Protective Effect of Ginkgolide B against Cognitive Impairment in Mice via Regulation of Gut MicrobiotaJiaming Liu, Tao Ye, Yuhe Zhang, Rui Zhang, Yu Kong, Yang Zhang, Jing Sun · 2021 · Journal of Agricultural and Food Chemistry
- Progress of RAGE Molecular Imaging in Alzheimer’s DiseaseYanyan Kong, Cuiping Liu, Yinping Zhou, Jingxuan Qi, Chencheng Zhang, Bomin Sun, Jiao Wang, Yihui Guan · 2020 · Frontiers in Aging Neuroscience
- Neuroprotective effects of geniposide on Alzheimer’s disease pathologyWeiZhen Liu, Guanglai Li, Christian Hölscher, Lin Li · 2015 · Reviews in the Neurosciences
- Geniposide Ameliorates Cognitive Deficits by Attenuating the Cholinergic Defect and Amyloidosis in Middle-Aged Alzheimer Model MiceZhao, Chunhui, Zhang, Haijing, Li, Hang, Lv, Cui, Liu, Xiaoli, Li, Zhi, Xin, Wenfeng, Wang, Yongyan, Zhang, Wensheng · 2017 · Neuropharmacology
- High Dietary Advanced Glycation End Products Impair Mitochondrial and Cognitive FunctionFiroz Akhter, Doris Chen, Asma Akhter, Alexander A. Sosunov, Allen Chen, Guy M. McKhann, Shi Fang Yan, Shirley ShiDu Yan · 2020 · Journal of Alzheimer s Disease
- The Mechanisms of Sevoflurane-Induced NeuroinflammationXiangfei Huang, Jun Ying, Danying Yang, Pu Fang, Xifeng Wang, Bin Zhou, Lieliang Zhang, Fang Yang, Wen Yu, Xing Liu et al. · 2021 · Frontiers in Aging Neuroscience
- Encapsulated native and glucagon-like peptide-1 transfected human mesenchymal stem cells in a transgenic mouse model of Alzheimer's diseasePetra Margarete Klinge, Kathrin Harmening, Miles C. Miller, Anna Heile, Christine Wallrapp, Peter Geigle, Thomas Brinker · 2011 · Neuroscience Letters
- Expression and cell distribution of receptor for advanced glycation end-products in the rat cortex following experimental subarachnoid hemorrhageHua Li, Wei Hua Wu, Qing Sun, Ming Liu, Wei Li, Xiangsheng Zhang, Meng‐Liang Zhou, Chun‐Hua Hang · 2013 · Brain Research
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- Aggregation of the Inflammatory S100A8 Precedes Aβ Plaque Formation in Transgenic APP Mice: Positive Feedback for S100A8 and Aβ ProductionsMaría Lodeiro, Elena Puerta, Muhammad-Al-Mustafa Ismail, Patricia Rodriguez‐Rodriguez, Annica Rönnbäck, Alina Codita, Cristina Parrado‐Fernández, Silvia Maioli, Francisco Javier Gil-Bea, Paula Merino‐Serrais et al. · 2016 · The Journals of Gerontology Series A
- RAGE Inhibition in Microglia Prevents Ischemia-Dependent Synaptic Dysfunction in an Amyloid-Enriched EnvironmentNicola Origlia, Chiara Criscuolo, Ottavio Arancio, Shushan Yan, Luciano Domenici · 2014 · Journal of Neuroscience
- Glucagon-like peptide-1 regulates mitochondrial biogenesis and tau phosphorylation against advanced glycation end product-induced neuronal insult: Studies in vivo and in vitroF-M An, S. Chen, Z. Xu, L. Yin, Yuanan Wang, A-R Liu, W-B Yao, X-D Gao · 2015 · Neuroscience
- Quercetin protects against the Aβ25–35-induced amnesic injury: Involvement of inactivation of RAGE-mediated pathway and conservation of the NVURui Liu, Tiantai Zhang, Dan Zhou, Xiaoyu Bai, Weiling Zhou, Chao Huang, Jun-ke Song, Fang-rui Meng, Caixia Wu, Lin Li et al. · 2012 · Neuropharmacology
- Chronic cerebral hypoperfusion alters amyloid-β transport related proteins in the cortical blood vessels of Alzheimer’s disease model mouseJingwei Shang, Toru Yamashita, Feng Tian, Xianghong Li, Xia Liu, Xiaowen Shi, Yumiko Nakano, Keiichiro Tsunoda, Emi Nomura, Ryo Sasaki et al. · 2019 · Brain Research
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- Association of the RAGE G82S polymorphism with Alzheimer’s diseaseJonny Daborg, Malin von Otter, Annica Sjölander, Staffan Nilsson, Lennart Minthon, Deborah Gustafson, Ingmar Gr. Skoog, Kaj Blennow, Henrik Zetterberg · 2010 · Journal of Neural Transmission
- A novel role for the Receptor for Advanced Glycation End-products in neural progenitor cells derived from adult SubVentricular ZoneVasco Meneghini, Maria Teresa Francese, Lorenzo Carraro, Mariagrazia Grilli · 2010 · Molecular and Cellular Neuroscience
- PET Radioligands for In Vivo Visualization of NeuroinflammationDieter Ory, Sofie Celen, Alfons Verbruggen, Guy M Bormans · 2014 · Current Pharmaceutical Design
- The Role of Basement Membranes in Cerebral Amyloid AngiopathyMatthew D. Howe, Louise D. McCullough, Akihiko Urayama · 2020 · Frontiers in Physiology
- Central nervous system effects of 5-HT7 receptors: a potential target for neurodegenerative diseasesAlejandro Quintero-Villegas, Sergio Iván Valdés‐Ferrer · 2022 · Molecular Medicine
- Chromatin Decondensation and T Cell Hyperresponsiveness in Diabetes-Associated HyperglycemiaNúria Martínez, Therese Vallerskog, Kim West, Cláudio Nunes-Alves, Jinhee Lee, Gregory W. Martens, Samuel M. Behar, Hardy Kornfeld · 2014 · The Journal of Immunology
- The Complexity of Sporadic Alzheimer’s Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular DysfunctionLorena Perrone, Oualid Sbai, Peter P. Nawroth, Angelika Bierhaus · 2012 · International Journal of Alzheimer s Disease
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- Microglia and Astrocytes in Alzheimer’s Disease in the Context of the Aberrant Copper Homeostasis HypothesisAmit Pal, Isha Rani, Anil Tukaram Pawar, Mario Picozza, Mauro Ciro Antonio Rongioletti, Rosanna Squitti · 2021 · Biomolecules
- Amyloid β precursor protein as a molecular target for amyloid β–induced neuronal degeneration in Alzheimer's diseaseElena Anahí Bignante, Florencia Heredia, Gerardo A. Morfini, Alfredo Lorenzo · 2013 · Neurobiology of Aging
- Synthesis and structure–activity relationships of tri-substituted thiazoles as RAGE antagonists for the treatment of Alzheimer’s diseaseYun Suk Lee, Hee Yeon Kim, Young-Ho Kim, Eun Joo Roh, Hogyu Han, Kye Jung Shin · 2012 · Bioorganic & Medicinal Chemistry Letters
- Mitochondrial Perturbation in Alzheimer's Disease and DiabetesFiroz Akhter, Doris Chen, S.F. Yan, S.S. Yan · 2017 · Progress in molecular biology and translational science
- Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and PathogenesisMcFarland, Karen N., Chakrabarty, Paramita · 2022 · Neurotherapeutics
- Youth Are Less Likely to be Food Insecure than Adults in the Same HouseholdMark Nord · 2013 · Journal of Hunger & Environmental Nutrition
- Aβ1-42 induces cell damage via RAGE-dependent endoplasmic reticulum stress in bEnd.3 cellsWenjing Chen, Yuanjin Chan, Wenbin Wan, Yaming Li, Chunyan Zhang · 2017 · Experimental Cell Research
- Pathology, Risk Factors, and Oxidative Damage Related to Type 2 Diabetes‐Mediated Alzheimer’s Disease and the Rescuing Effects of the Potent Antioxidant AnthocyaninMuhammad Sohail Khan, Muhammad Aimen Ikram, Tae Ju Park, Myeong Ok Kim · 2021 · Oxidative Medicine and Cellular Longevity
- Alzheimer’s genes in microglia: a risk worth investigatingAri Sudwarts, Gopal Thinakaran · 2023 · Molecular Neurodegeneration
- Pivotal role of AGE-RAGE axis in brain aging with current interventionsNikolaos Vitorakis, Christina Piperi · 2024 · Ageing Research Reviews
- Inflammatory risk factors and pathologies promoting Alzheimer's disease progression: is RAGE the key?Carmela Matrone, Mehdi Djelloul, Giulio Taglialatela, Lorena Perrone · 2015 · PubMed
- Pattern recognition receptors in chronic pain: Mechanisms and therapeutic implicationsJungo Kato, Nilesh M. Agalave, Camilla I. Svensson · 2016 · European Journal of Pharmacology
- The impact of chronic blackberry intake on the neuroinflammatory status of rats fed a standard or high-fat dietManuela Meireles, Cláudia Marques, Sónia Norberto, Iva Fernandes, Nuno Filipe da Cruz Batista Mateus, Catarina Rendeiro, Jeremy P.E. Spencer, Ana Faria, Conceição Calhau · 2015 · The Journal of Nutritional Biochemistry
- Ethanol Extract of Magnolia officinalis Prevents Lipopolysaccharide‐Induced Memory Deficiency via Its Antineuroinflammatory and Antiamyloidogenic EffectsYoung‐Jung Lee, Dong‐Young Choi, Yeo‐Pyo Yun, Sang‐Bae Han, Hwan Mook Kim, Kiho Lee, Seok Hwa Choi, Mhan‐Pyo Yang, Hyun Soo Jeon, Jea‐Hwang Jeong et al. · 2012 · Phytotherapy Research
- CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG miceBiju Bhargavan, Shawna M. Woollard, Jo Ellyn M. Mcmillan, Georgette D. Kanmogne · 2021 · Molecular Neurodegeneration
- Role of the Receptor for Advanced Glycation End Products (RAGE) and Its Ligands in Inflammatory ResponsesKaylen Cross, Stefan W. Vetter, Yousuf Alam, Md. Zahidul Hasan, Anupom Deb Nath, Estelle Leclerc · 2024 · Biomolecules
- Tau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null miceEmma Barroso, Jaume del Valle, David Porquet, Ana M. Vieira Santos, Laia Salvadó, Rosalía Rodríguez‐Rodríguez, Patrícia Gutiérrez, Marta Anglada‐Huguet, Jordi Alberch, Antoni Camins et al. · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Neurochemical effects of sepsis on the brainTatiana Barichello, Vijayasree Vayalanellore Giridharan, Carlos Henrique Rocha Catalão, Cristiane Ritter, Felipe Dal‐Pizzol · 2023 · Clinical Science
- LW-AFC, a new formula derived from Liuwei Dihuang decoction, ameliorates behavioral and pathological deterioration via modulating the neuroendocrine-immune system in PrP-hAβPPswe/PS1ΔE9 transgenic miceJianhui Wang, Xi Lei, Xiaorui Cheng, Xiaorui Zhang, Gang Liu, Junping Cheng, Yiran Xu, Zeng Ju, Wenxia Zhou, Yongxiang Zhang · 2016 · Alzheimer s Research & Therapy
- Microglia in the Aging RetinaMarcus Karlstetter, Thomas Langmann · 2014 · Advances in experimental medicine and biology
- HMGB1 signaling pathway in diabetes-related dementia: Blood-brain barrier breakdown, brain insulin resistance, and Aβ accumulationJae‐Ho Jeong, Dong Hoon Lee, Juhyun Song · 2022 · Biomedicine & Pharmacotherapy
- Daphnetin attenuates microglial activation and proinflammatory factor production via multiple signaling pathwaysWenwen Yu, Huanhuan Wang, Hangjie Ying, Yingying Yu, Dandan Chen, Weihong Ge, Liyun Shi · 2014 · International Immunopharmacology
- The neglected co-star in the dementia drama: the putative roles of astrocytes in the pathogeneses of major neurocognitive disordersW K Jo, Andrew Chi Kin Law, S. K. Chung · 2014 · Molecular Psychiatry
- Genetic deficiency of neuronal RAGE protects against AGE-induced synaptic injuryHongju Zhang, Yongfu Wang, Shijun Yan, Long Wu, Long Wu, Shirley Shi Du Yan, Shirley Shi Du Yan · 2014 · Cell Death and Disease
- Regulatory Effect of 25-hydroxyvitamin D3on Nitric Oxide Production in Activated MicrogliaJinyoung Hur, Pyeongjae Lee, Mi Jung Kim, Young‐Wuk Cho · 2014 · Korean Journal of Physiology and Pharmacology
- Receptors for Advanced Glycation End Products (RAGE): Promising Targets Aiming at the Treatment of Neurodegenerative ConditionsSuélyn Koerich, Gabriela Machado Parreira, Douglas Lamounier de Almeida, Rafael Pinto Vieira, Antônio Carlos Pinheiro de Oliveira · 2022 · Current Neuropharmacology
- Immune Regulatory Functions of Macrophages and Microglia in Central Nervous System DiseasesMichael Poppell, Grace Hammel, Yi Ren · 2023 · International Journal of Molecular Sciences
- Synthesis and Evaluation of [18F]RAGER: A First Generation Small-Molecule PET Radioligand Targeting the Receptor for Advanced Glycation EndproductsBrian P. Cary, Allen Frederick Brooks, Maria V. Fawaz, Lindsey R. Drake, Timothy J. Desmond, Phillip S. Sherman, Carole Quesada, Peter J. H. Scott · 2016 · ACS Chemical Neuroscience
- Infliximab ameliorates AD-associated object recognition memory impairmentDong Hyun Kim, Seong‐Min Choi, Jihoon Jho, Man‐Seok Park, Jisu Kang, Se Jin Park, Jong Hoon Ryu, Jihoon Jo, Hyun Hee Kim, Byeong Chae Kim · 2016 · Behavioural Brain Research
- Rhinacanthin C Alleviates Amyloid‐β Fibrils’ Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid‐β, and Interferon‐γ in Glial CellsKai‐An Chuang, Ming‐Han Li, Ni‐Hsuan Lin, Chih-Hsuan Chang, I-Huang Lu, I-Hong Pan, Tomoya Takahashi, Ming‐Der Perng, Shu‐Fang Wen · 2017 · Oxidative Medicine and Cellular Longevity
- Oxidative Stress, Advanced Glycation End Products (AGEs), and Neurodegeneration in Alzheimer’s Disease: A Metabolic PerspectiveVirginia Boccardi, Francesca Mancinetti, Patrizia Mecocci · 2025 · Antioxidants
- Therapeutic Targeting Strategies for Early- to Late-Staged Alzheimer’s DiseaseKang, You Jung, Diep, Yen N., Tran, Minh, Cho, Hansang · 2020 · International Journal of Molecular Sciences
- Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and NeurodegenerationRaúl Loera‐Valencia, Muhammad-Al-Mustafa Ismail, Julen Goikolea, María Lodeiro, Laura Mateos, Ingemar Björkhem, Elena Puerta, Mariana A. Romão, Cláudio M. Gomes, Paula Merino‐Serrais et al. · 2021 · Molecular Neurobiology
- Glycation & the RAGE axis: targeting signal transduction through DIAPH1Alexander G. Shekhtman, Ravichandran Ramasamy, Ann Marie Schmidt · 2016 · Expert Review of Proteomics
- Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1G93A Mouse Model of Amyotrophic Lateral SclerosisLee, John D., McDonald, Tanya S., Fung, Jenny N. T., Woodruff, Trent M. · 2020 · Molecular Neurobiology
- NLRP3 deficiency-induced hippocampal dysfunction and anxiety-like behavior in miceYulia K. Komleva, Olga L. Lopatina, Горина Яна Валерьевна, Аnton N. Shuvaev, Anatoly Chernykh, Ilia Potapenko, Alla B. Salmina · 2020 · Brain Research
- New insights in drug development for Alzheimer's disease based on microglia functionOu Qiao, Haixia Ji, Yi Zhang, Xinyu Zhang, Xueqian Zhang, Na Liu, Luqi Huang, Changxiao Liu, Wenyuan Gao · 2021 · Biomedicine & Pharmacotherapy
- Linking Alzheimer’s Disease and Type 2 Diabetes Mellitus via Aberrant Insulin Signaling and InflammationMohammad Amjad Kamal, Shubha Priyamvada, Arivarasu Natarajan Anbazhagan, Nasimudeen R. Jabir, Shams S. M. Tabrez, Nigel H. Greig · 2014 · CNS & Neurological Disorders - Drug Targets
- Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyleMark P. Mattson · 2015 · npj Aging and Mechanisms of Disease
- N-Docosahexanoylethanolamine Reduces Microglial Activation and Improves Hippocampal Plasticity in a Murine Model of NeuroinflammationAnna A. Tyrtyshnaia, Anatoly Bondar, S. P. Konovalova, Ruslan M. Sultanov, Igor Manzhulo · 2020 · International Journal of Molecular Sciences
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- The role of receptor for advanced glycation end products (RAGE) in neuronal differentiationJoanne Kim, Carthur K. Wan, Simon J. O’Carroll, Shamim B. Shaikh, Louise F. B. Nicholson · 2012 · Journal of Neuroscience Research
- Glycation: The angiogenic paradox in aging and age-related disorders and diseasesFrédéric Roca, Nicolas Grossin, Ph. Chassagne, François L. Puisieux, Éric Boulanger · 2014 · Ageing Research Reviews
- Protection against RAGE-mediated neuronal cell death by sRAGE-secreting human mesenchymal stem cells in 5xFAD transgenic mouse modelMyeongjoo Son, Seyeon Oh, Hyunjin Park, Hyosang Ahn, Junwon Choi, Hyung‐Ho Kim, Hye Sun Lee, Sojung Lee, Hye‐Jeong Park, Seung Up Kim et al. · 2017 · Brain Behavior and Immunity
- Anxiety and task performance changes in an aging mouse modelErika D. Nolte, Keith A. Nolte, Shirley ShiDu Yan · 2019 · Biochemical and Biophysical Research Communications
- Do inhalational anesthetics cause cognitive dysfunction?Rele Ologunde, Daqing Ma · 2011 · Acta anaesthesiologica Taiwanica
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- Receptor for advanced glycation end‐products: Biological significance and imaging applicationsIwona T. Dobrucki, Angelo Miskalis, Michael B. Nelappana, Catherine C. Applegate, Marcin Woźniak, Andrzej A. Czerwiński, Leszek Kalinowski, Lawrence W. Dobrucki · 2023 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
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