The DOI matches its Crossref record; 108 of the 108 references it cites were found in a registry or an index.
Endothelin‐1 gene regulation
Open accessAbstract
Over two decades of research have demonstrated that the peptide hormone endothelin‐1 (ET‐1) plays multiple, complex roles in cardiovascular, neural, pulmonary, reproductive, and renal physiology. Differential and tissue‐specific production of ET‐1 must be tightly regulated in order to preserve these biologically diverse actions. The primary mechanism thought to control ET‐1 bioavailability is the rate of transcription from the ET‐1 gene ( ednl ). Studies conducted on a variety of cell types have identified key transcription factors that govern ednl expression. With few exceptions, the cts‐acting elements bound by these factors have been mapped in the ednl regulatory region. Recent evidence has revealed new roles for some factors originally believed to regulate ednl in a tissue or hormone‐specific manner. In addition, other mechanisms involved in epigenetic regulation and mRNA stability have emerged as important processes for regulated ednl expression. The goal of this review is to provide a comprehensive overview of the specific factors and signaling systems that govern ednl activity at the molecular level.—Stow, L. R., Jacobs, M. E., Wingo, C. S., Cain, B. D. Endothelin‐1 gene regulation. FASEB J. 25, 16–28 (2011). www.fasebj.org
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Solis, A. G., Bielecki, P., Steach, H. R., Sharma, L., Harman, C. C. D., Yun, S., de Zoete, M. R., Warnock, J. N., To, S. D. F., York, A. G., et al. (2019) · Nature · doi:10.1038/s41586-019-1485-8 · Cited by 678
Radke, D., Jia, W., Sharma, D., Fena, K., Wang, G., Goldman, J., & Zhao, F. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201701461 · Cited by 256
Stow, L. R., Richards, J., Cheng, K.-Y., Lynch, I. J., Jeffers, L. A., Greenlee, M. M., Cain, B. D., Wingo, C. S., & Gumz, M. L. (2012) · Hypertension · doi:10.1161/hypertensionaha.112.190892 · Cited by 146
Self-citationRekker, K., Tasa, T., Saare, M., Samuel, K., Kadastik, Ü., Karro, H., Götte, M., Salumets, A., & Peters, M. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123789 · Cited by 43
Metadata
- Authors
- Stow, L. R., Jacobs, M. E., Wingo, C. S., & Cain, B. D.
- Venue
- The FASEB Journal
- Publisher
- Wiley
- Published
- 2010-09-13
- Volume
- 25
- Issue
- 1
- Pages
- 16-28
- ISSN
- 0892-6638 (ISSN-L)
- 1530-6860
- OpenAlex
- W2031200353
- Cited by
- 253
- References
- 108
- FWCI
- 8.56
- Type
- journal article
- Language
- en
- Open access
- green
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