The dynamic range of the human metabolome revealed by challenges

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α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population

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Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease

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Diet-induced Weight Loss and Phenotypic Flexibility Among Healthy Overweight Adults: A Randomized Trial

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Pharmacometabolomics in Drug Disposition, Toxicity, and Precision Medicine

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Postprandial metabolic events in mini-pigs: new insights from a combined approach using plasma metabolomics, tissue gene expression, and enzyme activity

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Postprandial activation of metabolic and inflammatory signalling pathways in human peripheral mononuclear cells

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Metabolomic Approaches in Cancer Epidemiology

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Model‐based data analysis of individual human postprandial plasma bile acid responses indicates a major role for the gallbladder and intestine

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Metabolomics Reveals Unexpected Responses to Oral Glucose

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Proteomics and metabolomics research in exercise and sport

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Branched-chain and aromatic amino acid levels response to an oral glucose load associated with gestational diabetes mellitus

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The repeatability of the abbreviated (4-h) Oral Fat Tolerance Test and influence of prior acute aerobic exercise

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Patterns of time since last meal revealed by sparse PCA in an observational LC-MS based metabolomics study

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Comparative analysis of circulating metabolomic profiles identifies shared metabolic alterations across distinct multistressor military training exercises

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The HuMet Repository: Watching human metabolism at work

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Mining for Peaks in LC-HRMS Datasets Using Finnee – A Case Study with Exhaled Breath Condensates from Healthy, Asthmatic, and COPD Patients

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Perspective: A potential role for NUS in metabolite‐based in vitro diagnostics

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Gadolinium-Based Paramagnetic Relaxation Enhancement Agent Enhances Sensitivity for NUS Multidimensional NMR-Based Metabolomics

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Is the quickness of resuscitation after hypoxia influenced by the oxygen concentration? Metabolomics in piglets resuscitated with different oxygen concentrations

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Mid- and long-term correlations of plasma metabolite concentrations measured by a targeted metabolomics approach

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Effects of Short-Term Dietary Protein Restriction on Blood Amino Acid Levels in Young Men

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Metabolic Perturbations Associated with both PFAS Exposure and Perinatal/Antenatal Depression in Pregnant Individuals: A Meet-in-the-Middle Scoping Review

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Plasma metabolomic and lipidomic profiles accurately classify mothers of children with congenital heart disease: an observational study

Mires, S., Sommella, E., Merciai, F., Salviati, E., Caponigro, V., Basilicata, M. G., Marini, F., Campiglia, P., Baquedano, M., Dong, T., et al. (2024) · Metabolomics · doi:10.1007/s11306-024-02129-8 · Cited by 7

Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Ldlr−/− Mice

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Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community

Izundegui, D. G., Miller, P. E., Shah, R. V., Clish, C. B., Walker, M. E., Mitchell, G. F., Gerszten, R. E., Larson, M. G., Vasan, R. S., & Nayor, M. G. (2022) · Cardiovascular Diabetology · doi:10.1186/s12933-022-01647-w · Cited by 8

Confounders in metabolomics

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Metabolomics of postprandial plasma alterations: a comprehensive Japanese study

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Metabolome trajectories in male and female athletes

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Limitations in metabolic plasticity after traumatic injury are only moderately exacerbated by physical activity restriction

Bruzina, A. S., Raymond‐Pope, C. J., Murray, K. J., Lillquist, T. J., Castelli, K. M., Bijwadia, S. R., Call, J. A., & Greising, S. M. (2024) · npj Metabolic Health and Disease · doi:10.1038/s44324-024-00006-5 · Cited by 6

Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults

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Association between Habitual Diet and the Postprandial Glucose Response—An Enable Study

Reik, A., Brandl, B., Schauberger, G., Wawro, N., Linseisen, J., Skurk, T., Volkert, D., Hauner, H., & Holzapfel, C. (2022) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200110 · Cited by 6

Lipidomics in nutrition research

Castro‐Alves, V., Orešič, M., & Hyötyläinen, T. (2022) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000852 · Cited by 6

Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study

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A Combined Lifestyle Intervention Induces a Sensitization of the Blood Transcriptomic Response to a Nutrient Challenge

Gehrmann, T., Beekman, M., Deelen, J., Partridge, L., van de Rest, O., Mei, L., Raz, Y., de Groot, C. P. G. M., van der Breggen, R., Reinders, M. J. T., et al. (2024) · doi:10.59368/agingbio.20240036 · Cited by 5

A systems approach to personalised nutrition: Report on the Keystone Symposium “Human Nutrition, Environment and Health”

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Identification of serological markers for pre- and postoperative fasting periods

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Critical assessment of quenching and extraction/sample preparation methods for microorganisms in metabolomics

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Phenotypic flexibility in nutrition research to quantify human variability: building the bridge to personalised nutrition

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Serum Metabolites Responding in a Dose-Dependent Manner to the Intake of a High-Fat Meal in Normal Weight Healthy Men Are Associated with Obesity

Bütikofer, U., Burnand, D., Portmann, R., Blaser, C., Schwander, F., Kopf-Bolanz, K. A., Laederach, K., Badertscher, R., Walther, B., & Vergères, G. (2021) · Metabolites · doi:10.3390/metabo11060392 · Cited by 5

Vitamin D status modulates innate immune responses and metabolomic profiles following acute prolonged cycling

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Single and Joined Behaviour of Circulating Biomarkers and Metabolic Parameters in High-Fit and Low-Fit Healthy Females

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Recent Advances in NMR Studies of Lipids

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Global testing of shifts in metabolic phenotype

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Network-based metabolite ratios for an improved functional characterization of genome-wide association study resultsPreprint

Krumsiek, J., Stückler, F., Suhre, K., Gieger, C., Spector, T. D., Soranzo, N., Kastenmüller, G., & Theis, F. J. (2016) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/048512 · Cited by 5

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson's DiseasePreprint

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Postprandial Metabolism, Inflammation, and Plasma Bile Acid Kinetics in a Rat Model: Implications for Translational Research

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Acute changes in the metabolome following resistance exercise combined with intake of different protein sources (cricket, pea, whey)

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Identifying critical age and gender-based metabolomic shifts in a Japanese population of the Tohoku Medical Megabank cohort

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Significance of 5’AMP-activated protein kinase in metabolomic regulation by skeletal muscle contraction

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Translating novel insights from age-related loss of skeletal muscle mass and phenotypic flexibility into diet and lifestyle recommendations for the elderly

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Application of Metabolomics to Renal and Cardiometabolic Diseases

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Four features of temporal patterns characterize similarity among individuals and molecules by glucose ingestion in humans

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Postprandial Metabolic Effects of Fiber Mixes Revealed by in vivo Stable Isotope Labeling in Humans

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Influence of diet and nutrition

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Diet, blood pressure, and heart disease—precision nutrition approaches to understand response to diet and predict disease risk

de Roos, B. (2021) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqab313 · Cited by 4

Kernel Weighted Least Square Approach for Imputing Missing Values of Metabolomics DataPreprint

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Urinary Metabolites Variation After High-Intensity Rowing Training and Potential Biomarker Screening for Exercise-Induced Muscle Damage

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Metabolic Adaptation during Cardiac Exercise Rehabilitation in Patients after a First Myocardial Infarction

Bossi, E., Nobile, M., Paoletti, F., Ticini, L., Serrao, S., Giglio, A., Parati, G., Zaza, A., Crotti, L., Malfatto, G., et al. (2026) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5c00997 · Cited by 3

Postprandial Metabolome Following a Low Glycaemic Index Meal-Challenge Test: A Narrative Review

Lau, Z. C., Yusof, B. N. M., Abas, F., Wahab, N. A., Zukiman, W. Z. H. H. W., & Ismail, A. (2022) · Malaysian Journal of Medical Sciences · doi:10.21315/mjms2022.29.5.2 · Cited by 3

Compartment-specific Metabolic Alterations to Insulin Reflect Adiposity-driven Variation and Predict Type 2 Diabetes

Sevilla-González, M. D. R., Hanson, P. A., Islam, J., Hsu, S. C., Tsoukas, M. A., Marliss, E. B., Reiner, A. P., Gravel, M., Kooperberg, C. L., Clish, C. B., et al. (2025) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaf454 · Cited by 3

Effect of Mori ramulus on the postprandial blood glucose levels and inflammatory responses of healthy subjects subjected to an oral high-fat/sucrose challenge: A double-blind, randomized, crossover clinical trial

Park, S.-Y., Kwon, O., & Kim, J. Y. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112552 · Cited by 3

Association between Genotype and the Glycemic Response to an Oral Glucose Tolerance Test: A Systematic Review

Bayer, S., Reik, A., von Hesler, L., Hauner, H., & Holzapfel, C. (2023) · Nutrients · doi:10.3390/nu15071695 · Cited by 3

NMR spectroscopy – a modern analytical tool for serum analytics of lipoproteins and metabolites

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Ms‐Based Metabolomics in Nutrition and Health Research

Ibáñez, C., & Simó, C. (2013) · Wiley eBooks · doi:10.1002/9781118537282.ch9 · Cited by 3

The history of β-aminoisobutyric acid: from a waste metabolite to a druggable compound for metabolic disease. A narrative review

Begriche, K., Massart, J., & Fromenty, B. (2026) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2026.178879 · Cited by 2

A Comprehensive Metabolomic and Microbial Analysis Following Dietary Amino Acid Reduction in Mice

AL-Ishaq, R. K., Ferrara, C. R., Stephan, N., Krumsiek, J., Suhre, K., & Montrose, D. C. (2024) · Metabolites · doi:10.3390/metabo14120706 · Cited by 2

A technical note on challenge tests in human volunteers for multidimensional phenotyping

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NMR-Spektroskopie – ein modernes Werkzeug zur Serum-Analytik von Lipoproteinen und Metaboliten

Baumstark, D., Pagel, P., Eiglsperger, J., Pfahlert, V., & Huber, F. (2014) · Journal of Laboratory Medicine · doi:10.1515/labmed-2012-0075 · Cited by 2

Metabolomics-Mediated Characterization of Endophytic Species in Recalcitrant Tree Species

Kumar, V., Teotia, P., Tuteja, N., Prasad, R., Goyal, P., Varma, A. K., Bisht, S., Singh, J., & Kumar, M. (2017) · Springer eBooks · doi:10.1007/978-3-319-49197-4_16 · Cited by 2

Dynamic modelling of an ACADS genotype in fatty acid oxidation – Application of cellular models for the analysis of common genetic variants

Matejka, K., Stückler, F., Salomon, M., Ensenauer, R. E., Reischl, E., Hoerburger, L., Grallert, H., Kastenmüller, G., Peters, A., Daniel, H., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0216110 · Cited by 2

Factors to consider in the verification of urine biomarkers

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Starvation

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Metabolic flexibility during normal pregnancy allows appropriate adaptation during gestation independently of BMI

Delgadillo‐Velazquez, J., Nambo‐Venegas, R., Patiño, N., Meraz‐Cruz, N., Razo-Azamar, M., Guevara‐Cruz, M., Fonseca, M., Montero, L. E. P., Ibarra‐González, I., Vela-Amieva, M. B., et al. (2021) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2021.06.007 · Cited by 1

Metabolomics: An Approach to Decode the Insight of Organism Functioning in Polluted Environments

Piliposyan, G., Merhi, C., Abdulkarim, S., Tawalbeh, M., Halalsheh, N., & Al–Othman, A. (2024) · Royal Society of Chemistry eBooks · doi:10.1039/bk9781837673131-00458 · Cited by 1

Almond consumption for 8 weeks differentially modulates metabolomic responses to an acute glucose challenge compared to crackers in young adults

Dhillon, J., Pandey, S., Newman, J. W. I., Fiehn, O., & Ortiz, R. M. (2025) · Nutrition Research · doi:10.1016/j.nutres.2025.01.003 · Cited by 1

Targeted and Untargeted Urinary Metabolomics in Exercise Science: A Systematic Review

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Acylcarnitine concentrations increase in response to an extended energy deficit, but return to baseline concentrations following a 2-week recovery in male US Army Rangers

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