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Disorders of Diminished Motivation
Abstract
Disorders of diminished motivation occur frequently in individuals with traumatic brain injury. Motivation is an ever-present, essential determinant of behavior and adaptation. The major syndromes of diminished motivation are apathy, abulia, and akinetic mutism. Depending on their etiology, disorders of diminished motivation may be a primary clinical disturbance, a symptom of another disorder, or a coexisting second disorder. This article presents a biopsychosocial approach to the assessment and management of motivational impairments in patients with traumatic brain injury. The recognition and differential diagnosis of disorders of diminished motivation, as well as the mechanism and clinical pathogenesis, are discussed.
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“Multiple studies have demonstrated that apathy in patients with lesions in aMCC is robustly associated with atrophy in aMCC ((Marin and Wilkosz, 2005) for a review see (Ducharme et al., 2017)).”
From Motivation in the Service of Allostasis: The Role of Anterior Mid-Cingulate Cortex (2019) · cites this paper as Marin and Wilkosz, 2005
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Metadata
- Authors
- Marin, R. S., & Wilkosz, P. A.
- Affiliations
- University of Pittsburgh (US)
- Venue
- Journal of Head Trauma Rehabilitation
- Published
- 2005-07
- Volume
- 20
- Issue
- 4
- Pages
- 377-388
- ISSN
- 0885-9701 (ISSN-L)
- OpenAlex
- W1973014562
- Cited by
- 241
- References
- 37
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 13 · 2023: 11 · 2022: 8 · 2021: 7 · 2020: 17 · 2019: 10 · 2018: 11 · 2017: 20 · 2016: 11 · 2015: 12 · 2014: 17 · 2013: 21 · 2012: 14
- FWCI
- 0.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Head Trauma Rehabilitation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- traumatic brain injury, apathy, abulia, akinetic mutism, motivational impairment, differential diagnosis, pathogenesis, biopsychosocial assessment, rehabilitation management
- MeSH terms
- Adaptation, Psychological, Mental Disorders, Brain Injuries, Central Nervous System Agents, Humans, Motivation, Neuropsychological Tests, Socioenvironmental Therapy
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