Theta rhythm increases in left superior temporal cortex during auditory hallucinations in schizophrenia: a case report
Abstract
Auditory hallucinations (AH), the perception of sounds and voices in the absence of external stimuli, remain a serious problem for a large subgroup of patients with schizophrenia. Functional imaging of brain activity associated with AH is difficult, since the target event is involuntary and its timing cannot be predicted. Prior efforts to image the patterns of cortical activity during AH have yielded conflicting results. In this study, MEG was used to directly image the brain electrophysiological events associated with AH in schizophrenia. We observed an increase in theta rhythm, as sporadic bursts, in the left superior temporal area during the AH states, whereas there was steady theta band activity in the resting state. The present finding suggests strong association of the left superior temporal cortex with the experience of AH in this patient. This is consistent with the hypothesis that AH arises from areas of auditory cortex subserving receptive language processing.
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Auditory hallucinations are linked to increased gamma-band activity in left auditory cortex.
“Initial case reports linked AHs to increased γ-band activity in left auditory cortex, 57,58”
From Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain? (2016) · cites this paper as [57]
Cites
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Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain?
Jardri, R., Hugdahl, K., Hughes, M., Brunelin, J., Waters, F., Alderson-Day, B., Smailes, D., Sterzer, P., Corlett, P. R., Leptourgos, P., et al. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw075 · Cited by 157 · see citing works
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Cortical activity associated with auditory hallucinations
Ropohl, A., Sperling, W., Elstner, S., Tomandl, B., Reulbach, U., Kaltenhäuser, M., Kornhuber, J., & Maihöfner, C. (2004) · NeuroReport · doi:10.1097/00001756-200403010-00028 · Cited by 67 · see citing works
- Authors
- Ishii, R., Shinosaki, K., Ikejiri, Y., Ukai, S., Yamashita, K., Iwase, M., Mizuno-Matsumoto, Y., Inouye, T., Yoshimine, T., Hirabuki, N., Robinson, S. E., & Takeda, M.
- Affiliations
- The University of Osaka (JP)
- Venue
- NeuroReport
- Published
- 2000-09
- Volume
- 11
- Issue
- 14
- Pages
- 3283-3287
- ISSN
- 0959-4965 (ISSN-L)
- OpenAlex
- W2048034199
- Cited by
- 79
- References
- 5
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 4 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 4 · 2015: 1 · 2014: 3 · 2013: 3 · 2012: 7
- FWCI
- 2.30
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroreport (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Keywords
- auditory hallucinations, schizophrenia, theta oscillations, auditory cortex, magnetoencephalography
- MeSH terms
- Adult, Auditory Cortex, Auditory Diseases, Central, Brain Mapping, Hallucinations, Humans, Functional Laterality, Male, Schizophrenia, Speech Perception, Theta Rhythm, Verbal Behavior, Magnetoencephalography
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