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Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial.

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Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

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The human gene for 11 beta-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization.

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Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids

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Comparison of trabecular bone microarchitecture and remodeling in glucocorticoid-induced and postmenopausal osteoporosis.

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The C/EBP Family of Transcription Factors

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Bone resorption induced by parathyroid hormone is strikingly diminished in collagenase-resistant mutant mice

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Osteoblastic 11β-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure

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Stimulation of Osteoprotegerin Ligand and Inhibition of Osteoprotegerin Production by Glucocorticoids in Human Osteoblastic Lineage Cells: Potential Paracrine Mechanisms of Glucocorticoid-Induced Osteoporosis

Hofbauer, L. C. (1999) · Endocrinology · doi:10.1210/en.140.10.4382 · Cited by 187

Clinical review 83: Mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis

CANALIS, E. M. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.81.10.3441 · Cited by 184

Disruption of the c/ebpα Gene in Adult Mouse liver

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Glucocorticoids inhibit bone resorption by isolated rat osteoclasts by enhancing apoptosis

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Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture

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Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression

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Cortisol downregulates osteoblast α1(I) procollagen mRNA by transcriptional and posttranscriptional mechanisms

Delany, A. M., Gabbitas, B., & CANALIS, E. M. (1995) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240570314 · Cited by 156

Expression and functional consequences of 11β-hydroxysteroid dehydrogenase activity in human bone

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Glucocorticoid Suppression of IGF I Transcription in Osteoblasts

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Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells.

Okazaki, R., Riggs, B. L., & Conover, C. A. (1994) · Endocrinology · doi:10.1210/endo.134.1.7506203 · Cited by 141

Cortisol Increases Interstitial Collagenase Expression in Osteoblasts by Post-transcriptional Mechanisms

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Dexamethasone Promotes Expression of Membrane-Bound Macrophage Colony-Stimulating Factor in Murine Osteoblast-Like Cells 1

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Human 11β-hydroxysteroid dehydrogenase: Studies on the stably transfected isoforms and localization of the type 2 isozyme within renal tissue

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Transgenic Mice Overexpressing Insulin-Like Growth Factor Binding Protein-5 Display Transiently Decreased Osteoblastic Function and Osteopenia

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Cortisol Inhibits the Synthesis of Insulin-like Growth Factor-binding Protein-5 in Bone Cell Cultures by Transcriptional Mechanisms

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Reversal of sexual dimorphism in splenic T lymphocyte responses after trauma-hemorrhage with aging

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Dexamethasone Promotes Expression of Membrane-Bound Macrophage Colony-Stimulating Factor in Murine Osteoblast-Like Cells

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Cortisol represses insulin-like growth factor II receptor transcription in skeletal cell cultures

Rydziel, S., & CANALIS, E. M. (1995) · Endocrinology · doi:10.1210/endo.136.10.7664643 · Cited by 34

Glucocorticoid regulation of insulin-like growth factor-binding protein expression in normal human osteoblast-like cells

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11β‐Hydroxysteroid‐dehydrogenase isoforms: tissue distribution and implications for clinical medicine

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11β-Hydroxysteroid Dehydrogenase, an Amplifier of Glucocorticoid Action in Osteoblasts

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Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

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Osteoporosis due to hormone imbalance: an overview of the effects of estrogen deficiency and glucocorticoid overuse on bone turnover

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MANAGEMENT OF ENDOCRINE DISEASE: Secondary osteoporosis: pathophysiology and management

Mirza, F., & CANALIS, E. M. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0118 · Cited by 343

Osteoblast physiology in normal and pathological conditions

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Bioresponsive drug delivery systems for the treatment of inflammatory diseases

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Mechanisms of glucocorticoid action in bone

CANALIS, E. M. (2005) · Current Osteoporosis Reports · doi:10.1007/s11914-005-0017-7 · Cited by 160

Mechanisms of glucocorticoid action in bone cells

Delany, A. M., Dong, Y., & CANALIS, E. M. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240560304 · Cited by 134

Glucocorticoids and Osteoporosis

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Glucocorticoid-induced osteoporosis

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Elucidating the role of the glucocorticoid receptor in glucocorticoid-induced osteoporosis

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