Cited by 537Musculoskeletal pain and rehabilitationPain Management and TreatmentPain Mechanisms and Treatments

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

A Randomized Controlled Trial of Intensive Neurophysiology Education in Chronic Low Back Pain

Moseley, G. Lorimer, Nicholas, Michael K., Hodges, Paul W.·2004·The Clinical Journal of Pain

DOI 10.1097/00002508-200409000-00007

Open this paper in CoChat — free account

Abstract

OBJECTIVES: Cognitive-behavioral pain management programs typically achieve improvements in pain cognitions, disability, and physical performance. However, it is not known whether the neurophysiology education component of such programs contributes to these outcomes. In chronic low back pain patients, we investigated the effect of neurophysiology education on cognitions, disability, and physical performance. METHODS: This study was a blinded randomized controlled trial. Individual education sessions on neurophysiology of pain (experimental group) and back anatomy and physiology (control group) were conducted by trained physical therapist educators. Cognitions were evaluated using the Survey of Pain Attitudes (revised) (SOPA(R)), and the Pain Catastrophizing Scale (PCS). Behavioral measures included the Roland Morris Disability Questionnaire (RMDQ), and 3 physical performance tasks; (1) straight leg raise (SLR), (2) forward bending range, and (3) an abdominal "drawing-in" task, which provides a measure of voluntary activation of the deep abdominal muscles. Methodological checks evaluated non-specific effects of intervention. RESULTS: There was a significant treatment effect on the SOPA(R), PCS, SLR, and forward bending. There was a statistically significant effect on RMDQ; however, the size of this effect was small and probably not clinically meaningful. DISCUSSION: Education about pain neurophysiology changes pain cognitions and physical performance but is insufficient by itself to obtain a change in perceived disability. The results suggest that pain neurophysiology education, but not back school type education, should be included in a wider pain management approach.

Integrity signals

Registry

Crossref · 10.1097/00002508-200409000-00007

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Pain Catastrophizing Scale: Development and validation.
Sullivan, M. J. L., Bishop, S. R., & Pivik, J. (1995) · Psychological Assessment · doi:10.1037//1040-3590.7.4.524 · Cited by 8,227
A Study of the Natural History of Back Pain: Part I
ROLAND, M., & MORRIS, R. (1983) · Spine · doi:10.1097/00007632-198303000-00004 · Cited by 3,395
Systematic review and meta-analysis of randomized controlled trials of cognitive behaviour therapy and behaviour therapy for chronic pain in adults, excluding headache
Morley, S., Eccleston, C., & Williams, A. (1999) · Pain · doi:10.1016/s0304-3959(98)00255-3 · Cited by 1,597
Efficacy of multidisciplinary pain treatment centers: a meta-analytic review.
Flor, H., Fydrich, T., & Turk, D. C. (1992) · Pain · doi:10.1016/0304-3959(92)90145-2 · Cited by 1,227
Psychosocial Predictors of Outcome in Acute and Subchronic Low Back Trouble
Burton, A. K., Tillotson, K. M., Main, C. J., & Hollis, S. (1995) · Spine · doi:10.1097/00007632-199503150-00014 · Cited by 700
Information and advice to patients with back pain can have a positive effect. A randomized controlled trial of a novel educational booklet in primary care.
Burton, A., Waddell, G., Tillotson, K., & Summerton, N. (1999) · Spine · doi:10.1097/00007632-199912010-00010 · Cited by 622
The Dominant Role of Psychosocial Risk Factors in the Development of Chronic Low Back Pain Disability
Gatchel, R. J., Polatin, P. B., & Mayer, T. G. (1995) · Spine · doi:10.1097/00007632-199512150-00011 · Cited by 532
Systematic review of outpatient services for chronic pain control.
McQuay, Moore, Eccleston, Morley, & Williams, A. C. D. C. (1997) · Health Technology Assessment · doi:10.3310/hta1060 · Cited by 423
Comparison of cognitive-behavioral group treatment and an alternative non-psychological treatment for chronic low back pain
Nicholas, M. K., Wilson, P. H., & Goyen, J. (1992) · Pain · doi:10.1016/0304-3959(92)90082-m · Cited by 271
Self-citation
Prediction of pain in patients with chronic low back pain: Effects of inaccurate prediction and pain-related anxiety
McCracken, L. M., Gross, R. T., Sorg, P. J., & Edmands, T. A. (1993) · Behaviour Research and Therapy · doi:10.1016/0005-7967(93)90117-d · Cited by 254

Show all 50 references

Research works printed but not linked: 9

Turner, 1988, J Consult Clin Psychol, 56, 261, 10.1037/0022-006X.56.2.261 · DOI
Bergquist-Ullman, 1977, Acta Orthop Scand, 1-, 117
Dehlin, 1981, Scand J Rehabil Med, 13, 1
Goossens, 1996, J Rheumatol, 23, 1246
Nachemson, 1992, Clin Orthop, 8-, 20
Linton, 1995, Scand J Rehabil Med Suppl, 32, 67
Sullivan, 1991, J Fam Pract, 32, 193
Sullivan, 1995, Psychol Asses, 7, 524, 10.1037/1040-3590.7.4.524 · DOI · Paper page
Richardson, 1995, 1, 2

Sorted by citations

Items 301–400 of 536

Chronic pain self-management support with pain science education and exercise (COMMENCE): study protocol for a randomized controlled trial
Miller, J., MacDermid, J. C., Walton, D. M., & Richardson, J. A. (2015) · Trials · doi:10.1186/s13063-015-0994-5 · Cited by 13
Are patients' and doctors' accounts of the first specialist consultation for chronic back pain in agreement?
White, K., Lee, J., & Williams, A. C. D. C. (2016) · Journal of Pain Research · doi:10.2147/jpr.s119851 · Cited by 9
“5,23,24 The educative role of the pain clinician is increasingly recognized as important 25–27 and valued by patients; 28 it aims to enable the patient to change the patient’s path from seeking a “cure” to learning how best to manage a chronic health problem.”
Validation of an educational booklet for people with chronic pain: EducaDor
Vieira, A. S. M., de Castro, K. V.-F., Camatti, J. R., de Oliveira, I. A. V. F., Benevides, S. D., & Sá, K. N. (2019) · Brazilian Journal Of Pain · doi:10.5935/2595-0118.20190008 · Cited by 9
Effects of spinal manipulation and pain education on pain in patients with chronic low back pain: a protocol of randomized sham-controlled trial
Vier, C., Bracht, M. A., Neves, M. L., Junkes-Cunha, M., & Santos, A. R. S. (2018) · Integrative Medicine Research · doi:10.1016/j.imr.2018.04.003 · Cited by 9
Efectividad de la educación en neurociencia del dolor aislada o combinada con ejercicio terapéutico en pacientes con dolor lumbar crónico: una revisión sistemática
Ramós-Martín, G. J., & Rodríguez‐Nogueira, Ó. (2021) · Fisioterapia · doi:10.1016/j.ft.2021.01.008 · Cited by 8
Effect of Pain Neuroscience Education with Conventional Physiotherapy via Telerehabilitation on Pain Catastrophizing and Function in Patients with Osteoarthritis Knee: A Randomized Controlled Trial
Supe, H. M., Mungikar, S., Katage, G., Garg, K., & Wani, S. K. (2023) · Journal of Mid-life Health · doi:10.4103/jmh.jmh_33_23 · Cited by 10
“[22] A study done by R V Briani et al and M Hurley et al stated that there are psychological benefits of exercise in patients with knee osteoarthritis.”
Result
Rückenschmerz – Schmerzverarbeitung und aktive segmentale Stabilisation
Puta, C., Herbsleb, M., Weiß, T., & Gabriel, H. W. (2011) · Manuelle Medizin · doi:10.1007/s00337-011-0818-y · Cited by 8
A process approach in manual and physical therapies: beyond the structural model
Lederman, E. (2015) · Cited by 8
Does readiness to change influence pain-related outcomes after an educational intervention for people with chronic pain? A pragmatic, preliminary study
Fletcher, R., BRAITHWAITE, F., Woodhouse, M., MacInnes, A. I., & Stanton, T. R. (2019) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2019.1636436 · Cited by 8
“© 2019 Taylor & Francis Group, LLC Meeus et al., 2012, 2010; Moseley, Nicholas, and Hodges, 2004; Robinson and King, 2013; Van Oosterwijck et al., 2013, 2011).”
BackgroundInfluential
Suggestions in Hypnosis to Aid Pain Education (SHAPE) in People with Chronic Low-Back Pain: A Pilot Feasibility Randomized, Controlled Trial
Pulling, B. W., Braithwaite, F. A., Moseley, G. L., Jensen, M. P., Burke, A. L. J., Collins, K. L., Hull, M. J., Jones, H. G., Cyna, A. M., Ferencz, N., et al. (2022) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2022.2105147 · Cited by 8
“Instead, the content was discussed in a conversational manner, as consistent with past work (Moseley et al., 2004).”
BackgroundResultSelf-citation
Nonpharmacologic Options for Treating Acute and Chronic Pain
Wu, P. I., Meleger, A. L., Witkower, A., Mondale, T., & Borg‐Stein, J. (2015) · PM&R · doi:10.1016/j.pmrj.2015.09.008 · Cited by 8
“their therapies and achieve the greatest return to their normal lives [14-16,26,31].”
Treat the Patient, Not the Label: A Pain Neuroscience Update
Louw, A., Schmidt, S. G., Zimney, K. J., & Puentedura, E. J. (2019) · Journal of Womenʼs Health Physical Therapy · doi:10.1097/jwh.0000000000000121 · Cited by 9
Pain neuroscience education is not superior to spinal physiology and ergonomics education within a short multidisciplinary rehabilitation program: A randomized controlled trial
Adenis, N., Wieczorek, V., Corbinau, S., Mortain, L., & Thévenon, A. (2024) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2024.103176 · Cited by 8
Behavioral therapy for temporomandibular disorders
Ohrbach, R. K., & Sharma, S. (2021) · Frontiers of Oral and Maxillofacial Medicine · doi:10.21037/fomm-20-65 · Cited by 7
“By the early 2000s, chronic pain research, including behavioral aspects of chronic back pain, had led to convincing evidence that behavior can both contribute to, and be exacerbated by, chronic pain (22-30).”
Background
Item development and pre-testing of an Osteoarthritis Conceptualisation Questionnaire to assess knowledge and beliefs in people with knee pain
Pulling, B. W., BRAITHWAITE, F., Butler, D. S., Vogelzang, A. R., Moseley, G. L., Catley, M. J., Murray, C. M., & Stanton, T. R. (2023) · PLoS ONE · doi:10.1371/journal.pone.0286114 · Cited by 7
Self-citation
Can a specific biobehavioral-based therapeutic education program lead to changes in pain perception and brain plasticity biomarkers in chronic pain patients? A study protocol for a randomized clinical trial
Di‐Bonaventura, S., Fernández‐Carnero, J., & Peña, R. F. (2024) · PLoS ONE · doi:10.1371/journal.pone.0289430 · Cited by 7
Bilateral leg symptoms – The T10 syndrome?
Geerse, W. K. (2011) · Manual Therapy · doi:10.1016/j.math.2011.08.003 · Cited by 7
Der Pflege das Kreuz stärken – Individualprävention „Rücken“ bei der Berufsgenossenschaft für Gesundheitsdienst und Wohlfahrtspflege
Kusma, B., Glaesener, J. J., Brandenburg, S., Pietsch, A., Fischer, K., Schmidt, J., Behl-Schön, S., & Pohrt, U. (2015) · Trauma und Berufskrankheit · doi:10.1007/s10039-015-0093-6 · Cited by 7
RETURN TO ADVANCED STRENGTH TRAINING AND WEIGHTLIFTING IN AN ATHLETE POST-LUMBAR DISCECTOMY UTILIZING PAIN NEUROSCIENCE EDUCATION AND PROPER PROGRESSION: RESIDENT'S CASE REPORT
Afzal, Z., Mansfield, C. J., Bleacher, J., & Briggs, M. S. (2019) · International Journal of Sports Physical Therapy · doi:10.26603/ijspt20190804 · Cited by 7
Preoperative pain neuroscience education for shoulder surgery: A case series
Louw, A., Rico, D., Langerwerf, L., Maiers, N., Diener, I., & Cox, T. A. (2020) · South African Journal of Physiotherapy · doi:10.4102/sajp.v76i1.1417 · Cited by 7
“The PNE programme was designed to include prepared pictures (Moseley 2004; Moseley et al. 2004; Van Oosterwijck et al. 2011), examples (Moseley et al. 2004; Van Oosterwijck et al. 2011) and metaphors (Van Oosterwijck et al. 2011).”
Method
Development of a pain neuroscience education program for post-traumatic stress disorder and pain
Benedict, T., Nitz, A. J., Abt, J. P., & Louw, A. (2019) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2019.1633717 · Cited by 7
“PNE, on the other hand, deemphasizes tissues and instead educates patients that chronic pain is often the result of a hypervigilant nervous system (Moseley, Nicholas, and Hodges, 2004).”
Background
The influence of education on pain during and following acute exercise in people with knee osteoarthritis: A randomised controlled trial
Ram, A., Kovats, A., Ho, D. S. F., Cooke, L., Ram, G. P., Gibbs, M. T., Booth, J., Thom, J. M., & Jones, M. D. (2025) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2025.103314 · Cited by 6
Relationship between pain and hesitation during movement initiation after distal radius fracture surgery: A preliminary study
Imai, R., Osumi, M., Ishigaki, T., & Morioka, S. (2018) · Hand surgery & rehabilitation · doi:10.1016/j.hansur.2018.02.003 · Cited by 6
Schmerzmechanismen und Clinical Reasoning
Luomajoki, H. A., & Schesser, R. (2022) · MSK – Muskuloskelettale Physiotherapie · doi:10.1055/a-1697-7490 · Cited by 6
Primary care management of acute whiplash injury
Sterling, M. M., & Kenardy, J. A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-7295-3946-3.10011-9 · Cited by 6
How do people understand their neuropathic pain? A Q-study
Martin, S., Daniel, C., & Williams, A. C. D. C. (2013) · Pain · doi:10.1016/j.pain.2013.10.021 · Cited by 6
“Early explanations that make sense of pain can mitigate its impact [37,41].”
Background
Group pain neuroscience education combined with supervised exercises reduces pain and improves function of Brazilian women with central sensitisation and a low level of education: a single-subject study
Marques, E. S., Meziat‐Filho, N., Ferreira, P. D. S., de Andrade, F. G., Ramsay, E., Corrêa, L. A., & Nogueira, L. A. C. (2018) · European Journal of Physiotherapy · doi:10.1080/21679169.2018.1531922 · Cited by 7
“of pain after PNE [56,59,63,64], despite the absence of the”
Background
Experiences with an educational program for patients with chronic widespread pain: a qualitative interview study
Goksör, C., Mannerkorpi, K., & Bergenheim, A. (2021) · Scandinavian Journal of Pain · doi:10.1515/sjpain-2021-0080 · Cited by 6
The Effect of a Pain Educational Video Upon Child Pain-Related Memory and the Moderating Role of Parental Pain- and Non-Pain-Attending Verbalizations: An Experimental Lab-Based Study
Rheel, E., Ickmans, K., Wauters, A., Ryckeghem, D. M. L. V., Barbé, K., Malfliet, A., & Vervoort, T. (2022) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsac044 · Cited by 6
Words and perceptions: therapy or threat?
Johnston, K., & Williams, M. T. (2018) · Journal of Physiotherapy · doi:10.1016/j.jphys.2018.04.002 · Cited by 6
Interpersonal Dyadic Influences of Pain Catastrophizing Between Caregivers and Children With Chronic Pain
Parker, D. M., Birnie, K. A., Yoon, I. A., & Bhandari, R. P. (2019) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000773 · Cited by 6
The Development and Testing of a Checklist to Study Behaviour Change Techniques used in a Treatment Programme for Canadian Armed Forces Members with Chronic Non-specific Low Back Pain
Harman, K., MacRae, M., & Vallis, M. (2014) · Physiotherapy Canada · doi:10.3138/ptc.2013-55bc · Cited by 6
Pain Education for Adolescents and Young Adults Living Beyond Cancer: An Interdisciplinary Meeting Report
Heathcote, L. C., Allen, J. M., Gunn, K. M., Fox, S., Harvie, D. S., Olver, I., Skinner, I., Smith, A., Stanton, T. R., Whitford, H. S., et al. (2019) · Journal of Adolescent and Young Adult Oncology · doi:10.1089/jayao.2019.0047 · Cited by 6
“8,23 A wealth of experimental and clinical evidence 24–26 supports these concepts and the notion that most persistent pains do not serve a useful protective function.”
Self-citation
Pain neuroscience education with physical activity improves physical and psychological outcomes in older women with chronic low back pain
Abiko, T., Murata, S., Iwase, H., Nonaka, K., Anami, K., Kikuchi, Y., Madoba, K., & Shiraiwa, K. (2025) · Scientific Reports · doi:10.1038/s41598-025-23951-7 · Cited by 13
“The significant reductions in PCS and FABQ scores observed in the PNE-PA group are consistent with findings from studies on both younger 11,12,39–41 and older adults 9 , suggesting that PNE effectively reduces maladaptive pain beliefs across age groups.”
Influential
Acceptability of multimodal and multidisciplinary group-based program for chronic low back pain: a qualitative study
Ochandorena‐Acha, M., Dalmau-Roig, A., Dürsteler, C., Vílchez-Oya, F., Ferrer, A., Martín‐Villalba, I., Obach, A., & Terradas‐Monllor, M. (2024) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2024.2377343 · Cited by 4
“…also receive supplementary materials (Bodes Pardo et al., 2018; Leventhal, Phillips, and Burns, 2016; Louw, Diener, Butler, and Puentedura, 2011; Louw, Zimney, Puentedura, and Diener, 2016; Moseley and Butler, 2015; Moseley, Nicholas, and Hodges, 2004; Ryan, Gray, Newton, and Granat, 2010)”
Biopsychosocial Approaches to Pediatric Chronic Pain Management
Essner, B. S., Tran, S. T., & Koven, M. L. (2020) · Springer eBooks · doi:10.1007/978-3-030-36287-4_16 · Cited by 6
“FastSchool”: A single session of an interprofessional pain management program for chronic pain patients inspired by cognitive behavioral therapy
Trouvin, A., Carvès, S., Rouquette, A., Coste, J., Meyer, S., Colin, F., Deleens, R., Medkour, T., Collet, M.-P., Perrot, S., et al. (2022) · Patient Education and Counseling · doi:10.1016/j.pec.2022.09.007 · Cited by 5
The Neuromatrix Theory of Pain and Transactional Theory of Stress and Coping: Improving Understanding of Pain Catastrophizing in Individuals With ACL Reconstruction and Knee Osteoarthritis
Genoese, F. M., Harkey, M. S., & Baez, S. (2022) · International Journal of Athletic Therapy & Training · doi:10.1123/ijatt.2022-0074 · Cited by 5
Fear-avoidance beliefs are associated with changes of back shape and function
Taheri, N., Becker, L. A., Fleig, L., Kołodziejczak, K., Cordes, L. M.-S., Hoehl, B. U., Grittner, U., Mödl, L., Schmidt, H., & Pumberger, M. (2025) · PAIN Reports · doi:10.1097/pr9.0000000000001249 · Cited by 5
“16,32 With respect to the frontal plane, previous findings demonstrated that spinal shape and profile only weakly correlated with Idiag M360 measures.”
A clinical contrast: physical therapists with low back pain treating patients with low back pain
Louw, A., Puentedura, E. J., & Zimney, K. J. (2015) · Physiotherapy Theory and Practice · doi:10.3109/09593985.2015.1062944 · Cited by 5
“By altering a patient’s beliefs, a therapeutic effect is possible (Moseley, 2004, 2005; Moseley, Nicholas, and Hodges, 2004) hence PNE aims to help reconceptualize a patient’s pain experience, by including explanations of: central sensitization (Nijs et al, 2011, 2013); peripheral neuropathic pain…”
BackgroundInfluential
Using the concept of ideomotor therapy in the treatment of a patient with chronic neck pain: A single system research design
McCarthy, S., Rickards, L. D., & Lucas, N. P. (2007) · International journal of osteopathic medicine · doi:10.1016/j.ijosm.2007.10.002 · Cited by 5
IFOMPT 2012: A Rendez-Vous of Hands and Minds, September 30–October 5, 2012, Québec City, Canada
Werstine, R., & Chesworth, B. M. (2012) · Journal of Orthopaedic and Sports Physical Therapy · doi:10.2519/jospt.2012.0302 · Cited by 5
Edukation beim Schmerzpatienten — eine besondere Herausforderung
Nobi, H.-G. (2017) · Schmerzmedizin · doi:10.1007/s00940-017-0637-x · Cited by 5
Watchful Waiting and Brief Education
Pradhan, B. B., Brox, J. I., & Indahl, A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-323-07293-9.00006-4 · Cited by 5
Perceptions of Pain Treatment in Pediatric Patients With Functional Gastrointestinal Disorders
Hale, A. E., Smith, A., Christiana, J. S., Burch, E., Schechter, N. L., Beinvogl, B. C., Paul, F., Henaghan, A. S., Logan, D. E., & Nurko, S. (2020) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000832 · Cited by 5
The Needs and Experiences of Patients on Pain Education and the Clinical Reasoning of Physical Therapists Regarding Cancer-Related Pain. A Qualitative Study
Eisen, T., Kooijstra, E. M., Groeneweg, R., Verseveld, M., & Hidding, J. T. (2021) · Frontiers in Pain Research · doi:10.3389/fpain.2021.675302 · Cited by 7
“Pain education with focus on understanding the neurophysiology of pain, can reduce incorrect thoughts and attitudes on pain and results in changes in physical activity, thereby realizing an active lifestyle (13, 14).”
Background
Yoga for People in Pain
Pearson, N. (2008) · International Journal of Yoga Therapy · doi:10.17761/ijyt.18.1.517t34t817066j34 · Cited by 5
Are you translating research into clinical practice? What to think about when it does not seem to be working
Murphy, M., Gibson, W., Moseley, G. L., & Rio, E. (2021) · British Journal of Sports Medicine · doi:10.1136/bjsports-2020-102369 · Cited by 5
Self-citation
Associative learning mechanisms may trigger increased burden of chronic pain; unlearning and extinguishing learned maladaptive responses should help chronic pain patients
Breivik, H. (2015) · Scandinavian Journal of Pain · doi:10.1016/j.sjpain.2015.11.012 · Cited by 4
Cognitive functional therapy as a complementary treatment for posture and disability of chronic neck pain: secondary analysis of a randomized controlled trial
Javdaneh, N., Shams, A., Shojaedin, S. S., Rydzik, Ł., Ambroży, T., & Chwała, W. (2022) · Acta of Bioengineering and Biomechanics · doi:10.37190/abb-02187-2023-03 · Cited by 4
Effectiveness of in-group versus individually administered pain neuroscience education on clinical and psychosocial outcomes in patients with chronic low back pain: randomized controlled study protocol
Salazar‐Méndez, J., Cuyúl-Vásquez, I., Ponce‐Fuentes, F., Núñez‐Cortés, R., Méndez-Rebolledo, G., & Fuentes, J. (2024) · PeerJ · doi:10.7717/peerj.17507 · Cited by 4
“PNE has shown positive results on the kinesiophobia, catastrophizing, pain intensity, disability, and physical performance in patients with CLBP ( Moseley, Nicholas & Hodges, 2004 ; Ryan et al., 2010 ; Louw et al., 2011 ; Malfliet et al., 2017 ; Rufa, Beissner & Dolphin, 2018 ; Núñez Cortés et al.,…”
Conservative Management of Occipital Neuralgia Supported by Physical Therapy: A Review of Available Research and Mechanistic Rationale to Guide Treatment
Deuel, D., Sandgren, A., Nelson, E. O., Cropes, M., Deacon, A., Houdek, T., & Abd-Elsayed, A. A. (2024) · Current Pain and Headache Reports · doi:10.1007/s11916-024-01288-6 · Cited by 4
Kinematic Analyses Using Finger-Tapping Task for Patients After Surgery With Distal Radius Fracture at Acute Phase
Imai, R., Osumi, M., Ishigaki, T., & Morioka, S. (2020) · Hand · doi:10.1177/1558944720949952 · Cited by 4
Physiotherapy Modalities used in the Management of Chronic Low Back Pain
Naidoo, V., Mudzi, W., Ntsiea, V., & Becker, P. (2012) · South African Journal of Physiotherapy · doi:10.4102/sajp.v68i1.8 · Cited by 4
Pain-processing mechanisms in whiplash associated disorders
Curatolo, M., & Sterling, M. M. (2011) · Elsevier eBooks · doi:10.1016/b978-0-7295-3946-3.10005-3 · Cited by 4
Preventing and modulating learned wound pain.
Sussman, C. (2008) · PubMed · Cited by 4
Information und Edukation des Patienten
Nobis, H.-G., & Pielsticker, A. (2016) · Springer eBooks · doi:10.1007/978-3-642-29775-5_15 · Cited by 4
Controlling for "confounders" in psychosocial pain research.
Sullivan, M. (2016) · Pain · doi:10.1097/j.pain.0000000000000493 · Cited by 5
“it is described as a measure of satisfaction with one’s clinician(8); in another article, it is described as a measure of therapist equivalence.(7) When the referent construct of a scale”
Background
Why might fears and worries persist after a pain education–grounded multimodal intervention for chronic back pain? A qualitative study
Rizzo, R. R. N., Wand, B. M., Leake, H. B., O’Hagan, E. T., Traeger, A. C., Gustin, S. M., Moseley, G. L., Sharma, S., Cashin, A. G., Bagg, M. K., et al. (2024) · PAIN Reports · doi:10.1097/pr9.0000000000001197 · Cited by 3
“22 Although there is evidence that societal beliefs about back pain may have changed over time, 27 many people still hold strong biomedical views about back pain and uncertainties about its management.”
Self-citation
The role of systemic and nervous system factors in patients with shoulder pain: a perspective review
Mertens, M. G., Meeus, M., Ingwersen, K. G., Christiansen, D. H., & Struyf, F. (2025) · Postgraduate Medicine · doi:10.1080/00325481.2025.2571943 · Cited by 3
“The modern iteration, pain science education (PSE), evolved from PNE [108] or ‘explaining pain’ [109] and was first emerged as ‘intensive neurophysiology education’ [110].”
Saudi Clinical Practice Guideline for the Assessment and Management of Low Back Pain and Sciatica in Adults
Aldera, M., Alturkistany, A. Q., Rayes, H. A., Gabriel Rada, G., Alsulaimany, H. H., Alsobayel, H., Alghamdi, K., Awwad, W. M., Alyamani, O. A., Bedaiwi, M. K., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15020528 · Cited by 3
Pain Neuroscience Education in Elementary and Middle Schools
Louw, A., Louw, C., Podalak, J., Zimney, K. J., DeLorenzo, J., Maiers, N., Puentedura, E. J., & Mintken, P. E. (2023) · Pediatric Physical Therapy · doi:10.1097/pep.0000000000001018 · Cited by 3
Nurses in an interdisciplinary pain clinic: the experience of a university extension
Hortense, P., Grossi, M. G., Pinto, M. J. D. S., Prediger, K. M., Xavier, P. C., & Deliberali, V. F. (2024) · Escola Anna Nery · doi:10.1590/2177-9465-ean-2024-0059en · Cited by 3
Study protocol for Norwegian Psychomotor Physiotherapy versus Cognitive Patient Education in combination with active individualized physiotherapy in patients with long-lasting musculoskeletal pain – a randomized controlled trial
Dragesund, T., & Kvåle, A. (2016) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-016-1159-8 · Cited by 3
Étude préliminaire descriptive sur l’éducation à la neurophysiologie de la douleur chez le patient lombalgique chronique : illustration par une brochure
Mansouri, E., & Kostur, L. (2017) · Kinésithérapie la Revue · doi:10.1016/j.kine.2017.11.003 · Cited by 3
Pain Neuroscience Education for Older Adults
Watson, S., Louw, A., Wingood, M., Rico, D., Podolak, J., Maiers, N., & Cox, T. (2021) · Physical & Occupational Therapy In Geriatrics · doi:10.1080/02703181.2021.1970692 · Cited by 3
Single session compared with multiple sessions of education and exercise for older adults with spinal pain in an advanced practice physiotherapy model of care: protocol for a randomised controlled trial
Lafrance, S., Santaguida, C., Perreault, K., Bath, B. L., Thavorn, K., Feldman, D. E., Hébert, L. J., Fernandes, J., & Desmeules, F. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-053004 · Cited by 3
Expressed Beliefs about the Cause of Pain in a Pediatric Population: A Qualitative Study
Fernández, L. M., Salvat, I., & Adillón, C. (2023) · Children · doi:10.3390/children10061007 · Cited by 3
Occupational Pain Medicine: From Paradigm Shift in Pain Neuroscience to Contextual Model of Care
Miller, S. M. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00188 · Cited by 3
Investigating the Mechanisms of Graded Sensorimotor Precision Training in Adults With Chronic Nonspecific Low Back Pain: Protocol for a Causal Mediation Analysis of the RESOLVE Trial
Cashin, A. G., Lee, H., Bagg, M. K., Wand, B. M., O’Hagan, E. T., Rizzo, R. R. N., Stanton, T. R., Moseley, G. L., & McAuley, J. H. (2021) · JMIR Research Protocols · doi:10.2196/26053 · Cited by 4
“These are cognitions about the back, pain, and movement [69]; back-specific body representations [43]; fidelity and weighting of sensory information from the back [70,71]; and spinal control, movement coordination, and functional tolerance for meaningful activities [33,72].”
BackgroundMethodSelf-citation
A randomised controlled trial of ‘clockwise’ ultrasound for low back pain
Louw, A., Zimney, K. J., Landers, M. R., Luttrell, M., Clair, B., & Mills, J. (2016) · South African Journal of Physiotherapy · doi:10.4102/sajp.v72i1.306 · Cited by 3
“This concurs with recent pain neuroscience research whereby education alone has shown an immediate increase in SLR (Louw et al. 2015b; Louw, Diener & Puentedura 2015a; Moseley 2004; Moseley et al. 2004).”
MethodResult
The Pelvis and Sacroiliac Joint: Physical Therapy Patient Management Using Current Evidence
Jackson, R., & Porter, K. (2016) · Orthopaedic Section, APTA, Inc. eBooks · doi:10.17832/isc.2016.26.2.9 · Cited by 3
Efectividad de la educación basada en neurociencias en pacientes con dolor lumbar crónico: revisión sistemática con metaanálisis
Valdés-Orrego, I., Araya‐Quintanilla, F., Muñoz-Cuevas, M. J., Maturana-Madrid, K., & Navarrete-Cabrera, M. (2018) · Fisioterapia · doi:10.1016/j.ft.2018.08.001 · Cited by 3
Motor control in chronic pain: new ideas for effective intervention
Moseley, G. L. (2005) · Elsevier eBooks · doi:10.1016/b978-044310178-6.50036-0 · Cited by 3
Self-citation
After the Tango in the Doorway: An Autoethnography of Living with Persistent Pain
Thompson, B. L. (2019) · Springer eBooks · doi:10.1007/978-3-030-24154-4_2 · Cited by 3
Neuroimaging of Pain: A Psychosocial Perspective
Somers, T. J., Moseley, G. L., Keefe, F. J., & Kothadia, S. M. (2010) · Springer eBooks · doi:10.1007/978-1-4419-6373-4_17 · Cited by 3
Self-citation
Patient action as means and end of chronic pain care: Risks and routes to meaningful action
Williams, A. C. D. C. (2017) · Pain · doi:10.1097/j.pain.0000000000000929 · Cited by 2
The Effect of 6 Weeks of Dynamic Neuromuscular Stabilization Exercises on Motor Control, Cardiovascular Fitness, and Respiratory Performance in Overweight and Obese Women
Binabaji, S., Rahimi, N. M., & Esfahani, M. (2025) · Biological Research For Nursing · doi:10.1177/10998004251337451 · Cited by 2
“Furthermore, DNS encourages individuals to focus on their “ abled-self ” rather than their “ disabled-self, ” instilling reassurance about their physical capabilities (Moseley et al., 2004).”
Co-design of novel resources for pain science education implementation: PainPLaN (Personalised Learning and Navigation to pain education resources)
Wilson, M. V., Davis, A., BRAITHWAITE, F., Arnold, J. B., Ninnes, P., Wing, M. N., Nicoll, A., & Stanton, T. R. (2025) · Pain · doi:10.1097/j.pain.0000000000003664 · Cited by 3
Toward a shared framework for therapeutic pain education: a Delphi-based international consensus
Di‐Bonaventura, S., Gurdiel‐Álvarez, F., Reina‐Varona, Á., Cuenca‐Martínez, F., Fernández‐Carnero, J., Grande‐Alonso, M., Huysmans, E., Touche, R. L., Montero-Cuadrado, F., Núñez-Cortés, R., et al. (2026) · Physical Therapy · doi:10.1093/ptj/pzag029 · Cited by 2
Évaluation de l’efficacité de l’éducation à la neurophysiologie de la douleur comparée à une éducation conventionnelle, associée à une réadaptation multidisciplinaire, chez des patients lombalgiques chroniques : un protocole pour un essai contrôlé et randomisé
Adenis, N., Moretto, F., Hanot, Q., Wieczorek, V., Duhamel, A., & Thévenon, A. (2020) · Kinésithérapie la Revue · doi:10.1016/j.kine.2020.05.018 · Cited by 2
Virtual McKenzie extension exercises for low back and leg pain: a prospective pilot exploratory case series
Louw, A., Farrell, K. P., Nielsen, A., O’Malley, M., Cox, T., & Puentedura, E. J. (2022) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2022.2092822 · Cited by 2
Investigating the Effect of Pain Neurophysiology Education in the Treatment of Cervicogenic Headache: A Randomized Clinical Trial
Ghasemi, E., Naji, S. S., Najafi, M. R., Ghasemi, M., & Karimi, A. (2023) · Middle East Journal of Rehabilitation and Health Studies · doi:10.5812/mejrh-136156 · Cited by 2
“However, these models have not only shown limited effects in reducing pain and disability, but may also increase fear in patients, which in turn can amplify their pain (29, 31).”
BackgroundResult
Duloxetine and cognitive behavioral therapy with phone-based support for the treatment of chronic musculoskeletal pain: study protocol of the PRECICE randomized control trial
Ang, D. C., Davuluri, S., Kaplan, S. G., Keefe, F. J., Rini, C. K., Miles, C. M., & Chen, H. (2024) · Trials · doi:10.1186/s13063-024-08158-x · Cited by 2
“The psychometric properties of PCS are well established [69–71] including sensitivity to change [72, 73].”
Implementation of back to living well, a community-based program for the tertiary prevention of low back pain: a study protocol
Macedo, L. G., Pelino, S. D., Santos, V. S., Richardson, J. A., MacDermid, J. C., Hancock, M. J., Battié, M. C., Saragiotto, B. T., Hayden, J. A., Rushton, A. B., et al. (2024) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-024-07712-7 · Cited by 3
“Education will be integrated and comprise information on LBP, [16, 42], introduction to self-management, [43, 44] graded activity and pain neurophysiology [45].”
Background
Anticipated Barriers and Facilitators to Engaging in a Novel Virtual Reality Program for Lower Phantom Limb Pain
Crooks, M., Smith, M. S. D., Reynolds, K., Hammond, E., Gross, P., Pankratz, L., & El-Gabalawy, R. M. (2025) · Journal of Medical Extended Reality · doi:10.1089/jmedxr.2024.0047 · Cited by 2
“3,12 34 Meeting VR GMI expectations: The importance of patient-centered care While psychoeducation can prime realistic expectations, the qualitative themes also allude to the importance of patient-centered care.”
Placeboeffekte in wissenschaftlichen Studien
Luomajoki, H. A., & Morf, R. (2020) · Der Schmerzpatient · doi:10.1055/a-1205-5291 · Cited by 2
“[19] Moseley GL, Nicholas MK, Hodges PW.”
Background
Lower thoracic syndrome
Farooq, M. N. (2017) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.333.12340 · Cited by 2
Examination and Treatment of Lumbopelvic Spine Disorders
Olson, K. A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-26306-1.00004-6 · Cited by 2
Schmerzmechanismen und Clinical Reasoning
Luomajoki, H. A., & Schesser, R. (2021) · Der Schmerzpatient · doi:10.1055/a-1519-2637 · Cited by 2
A protocol for a randomized trial on pain neuroscience education vs. routine physical therapy in people with chronic neck pain
Soleiman, F., Mohammadi, H. K., Saadat, M., Derisfard, F., & Nassadj, G. (2022) · European Journal of Translational Myology · doi:10.4081/ejtm.2022.10674 · Cited by 2
Opioid Syndrome
Kamen, L. B., & Feeko, K. J. (2014) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2014.01.005 · Cited by 2
“Nociceptive signals are not perceived as pain until the brain is engaged in a neuromatrix of CNS structural areas relaying the peripheral signals to perceptual and functional areas geared to execute a response.(25) The neuromatrix, as conceived by Melzac and others, represents the web of the sensory, affective, and co…”
Background
A focus group study to understand biases and confounders in a cluster randomized controlled trial on low back pain in primary care in Norway
Werner, E. L., Løchting, I., Storheim, K., & Grotle, M. (2018) · BMC Family Practice · doi:10.1186/s12875-018-0759-9 · Cited by 2
“Moseley L, Nicholas M, Hodges P.”
BackgroundMethodInfluential
Principles of Management of Cervical Disorders
Jull, G. A., Sterling, M. M., Falla, D., Treleaven, J. M., & O’Leary, S. P. (2008) · Elsevier eBooks · doi:10.1016/b978-0-443-10047-5.50017-5 · Cited by 2
Evidence-informed Clinical Decision-Making for Lower Extremity Hyperalgesia and Allodynia in a 42 year-old Woman Presenting with Low Back Pain -A Case Report
Manickaraj, N., & Vijayakumar, P. (2011) · Figshare · Cited by 2
Pain is mechanism
van Rysewyk, S. P. (2013) · Figshare · doi:10.25959/23208842 · Cited by 2
Case descriptions
Sterling, M. M., Rebbeck, T. J., & Kenardy, J. A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-7295-3946-3.10017-x · Cited by 2
Discography
Vivian, D., & Landers, M. H. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4160-3779-8.10038-7 · Cited by 2
Chronische pijn bij patiënten met het chronisch vermoeidheidssyndroom: een indicatie voor fysiotherapie?
Nijs, J., & Meeus, M. (2004) · Bohn Stafleu van Loghum eBooks · doi:10.1007/978-90-313-7316-1_49 · Cited by 2
The Effect of a Brief Physician-Delivered Neurobiologically Oriented, Cognitive Behavioural Therapy (Brief-CBT) Intervention on Chronic Pain Acceptance in Youth with Chronic Pain—A Randomized Controlled Trial.
Simmonds, M. K., Dick, B. D., Verrier, M. J., Reid, K. L., Jamieson-Lega, K., Balisky, K. J., Davey, A. E., & Freeman, K. M. (2022) · Children · doi:10.3390/children9091293 · Cited by 1
“A previous study looking at the efficacy of brief education intervention found that neurophysiology education led to some normalization of attitudes and beliefs about pain, a reduction in catastrophizing, and improvement in physical performance [20].”
Background

Authors: Moseley, G. L., Nicholas, M. K., & Hodges, P. W.
Affiliations: The University of Sydney (AU)
Corresponding author: Moseley, G. Lorimer
Hodges, Paul W.
ORCID: Moseley, G. Lorimer
Nicholas, Michael K.
Hodges, Paul W.
Venue: The Clinical Journal of Pain
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004
Volume: 20
Issue: 5
Pages: 324-330
ISSN: 0749-8047 (ISSN-L)
DOI: 10.1097/00002508-200409000-00007
OpenAlex: W2078673653
Cited by: 537
References: 50
Citations by year: 2026: 16 · 2025: 23 · 2024: 36 · 2023: 32 · 2022: 24 · 2021: 50 · 2020: 45 · 2019: 31 · 2018: 34 · 2017: 31 · 2016: 40 · 2015: 34 · 2014: 18 · 2013: 20 · 2012: 16
FWCI: 2.30
Type: journal article
Language: en
Open access: closed
Locations: Clinical Journal of Pain (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Keywords: neurophysiology education, chronic low back pain, pain-related cognitions, pain catastrophizing, pain attitudes, disability, physical performance, cognitive-behavioral pain management, physiotherapy education
MeSH terms: Adult, Analysis of Variance, Chronic Disease, Double-Blind Method, Female, Humans, Male, Middle Aged, Neurophysiology, Pain Measurement, Patient Education as Topic, Psychomotor Performance, Surveys and Questionnaires, Cognitive Behavioral Therapy, Low Back Pain

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A Randomized Controlled Trial of Intensive Neurophysiology Education in Chronic Low Back Pain

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks