Cited by 148Effects of Radiation ExposureRadiation Therapy and DosimetryRadiation Dose and Imaging

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

DOSE RESPONSE RELATIONSHIPS FOR ACUTE IONIZING-RADIATION LETHALITY

Anno, G. H., Young, R. W., Bloom, R. M., Mercier, J. R.·2003·Health Physics

Abstract

A review and analysis of the dose response relationship for the probability of acute lethality from prompt or short-term exposure to ionizing radiation is presented. The purpose of this analysis is to provide recommendations concerning estimates of casualties expected from radiation accidents, the use of nuclear weapons, or possible terrorist activities. Previous work on acute ionizing radiation-induced lethality risk together with a collection of dose response relationships are analyzed and presented based on historical case data and expert opinion that have evolved from whole-body radiation therapy experience, radiation exposure accidents, nuclear weapon detonations, and animal experimentation. The nature of the data reviewed ranges from direct individual events to those offered according to collective expert opinion and consensus published as journal articles and in various technical documents and reports. The dose response relationships are expressed as two-parameter (median exposure level and slope) probability distribution models as a function of radiation exposure in terms of a free-in-air dose. Twelve different dose response relationships are presented and discussed, including the impact of some medical care.

Overview

Integrity signals

Registry

Crossref · 10.1097/00004032-200305000-00001

Cites

15 of 15 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

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  • Acute whole-body absorbed doses of 6-7 Gy are considered the human LD50/60, the lethal dose for 50% of the population in 60 days, even with supportive treatment.

    “Acute whole-body absorbed doses of 6 -7 Gy are considered the human LD50/60, that is, the lethal dose for 50% of the population in 60 d, even with supportive treatment (typically antibiotic and transfusion support) ( 89 ).”

Citations

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Research works printed but not linked: 2

  1. Cronkite, 1958, U S Armed Forces Med J, 9, 313
  2. Murnaghan, 1993, Health Phys, 64, 318

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Metadata

Authors
Anno, G. H., Young, R. W., Bloom, R. M., & Mercier, J. R.
Corresponding author
Anno, G. H.
Venue
Health Physics
Published
2003-05
Volume
84
Issue
5
Pages
565-575
ISSN
0017-9078 (ISSN-L)
OpenAlex
W2037314608
Cited by
148
References
15
Citations by year
2026: 2 · 2025: 6 · 2024: 3 · 2023: 10 · 2022: 5 · 2021: 7 · 2020: 8 · 2019: 8 · 2018: 8 · 2017: 7 · 2016: 8 · 2015: 8 · 2014: 3 · 2013: 8 · 2012: 15
FWCI
2.95
Type
journal article
Language
en
Open access
closed
Locations
  • Health Physics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Effects of Radiation Exposure
  • Physical Sciences › Physics and Astronomy › Radiation › Radiation Therapy and Dosimetry
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
Keywords
dose-response relationship, ionizing radiation, radiation accidents, nuclear weapons, radiological terrorism, radiation casualties, probability distribution model, slope parameter, animal experimentation
MeSH terms
Animals, Dose-Response Relationship, Radiation, Humans, Lethal Dose 50, Models, Biological, Radiation Dosage, Radiation Injuries, Radiation, Ionizing, Radiometry, United States, Whole-Body Irradiation, Models, Statistical, Risk Assessment

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