EXPERIMENTAL KURU ENCEPHALOPATHY IN CHIMPANZEES AND SPIDER MONKEYS: ELECTRON— MICROSCOPIC STUDIES
Abstract
Peter W. Lampert, M.D., Kenneth M. Earle, M.D., Clarence J. Gibbs, Jr., Ph.D., D. Carletox Gajdusek, M.D.; Experimental Kuru Encephalopathy in Chimpanzees
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As early as 1969, Lampert et al. suggested that spongiform change is related to autophagy.
“It is of utmost interest that as early as 1969, Lampert et al (having cited an earlier article by Arstila et al [88]) suggested that the spongiform change is somehow related to autophagy (84).”
From Kuru (2012) · cites this paper as [84]
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Kuru, the First Human Prion Disease
Liberski, P. P., Gajos, A., Sikorska, B., & Lindenbaum, S. (2019) · Viruses · doi:10.3390/v11030232 · Cited by 69 · see citing works
Liberski, P. P., Sikorska, B., Lindenbaum, S., Goldfarb, L. G., McLean, C., Hainfellner, J. A., & Brown, P. (2012) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e3182444efd · Cited by 50 · see citing works
An unusual structure in Kuru brain
Peat, A., & Field, E. J. (1970) · Acta Neuropathologica · doi:10.1007/bf00686775 · Cited by 13 · see citing works
- Authors
- LAMPERT, P. W., EARLE, K. M., GIBBS, C. J., & GAJDUSEK, D. C.
- ORCID
- LAMPERT, PETER W.
- Venue
- Journal of Neuropathology and Experimental Neurology
- Publisher
- Oxford University Press (OUP)
- Published
- 1969-07
- Volume
- 28
- Issue
- 3
- Pages
- 353-370
- ISSN
- 0022-3069 (ISSN-L)
- OpenAlex
- W2062609940
- Cited by
- 71
- References
- 0
- Citations by year
- 2019: 1 · 2017: 1 · 2013: 2 · 2012: 1
- FWCI
- 4.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuropathology & Experimental Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Prion Diseases and Protein Misfolding
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Amyloidosis: Diagnosis, Treatment, Outcomes
- Keywords
- experimental infection, chimpanzees, spider monkeys, nonhuman primate model, prion disease, experimental transmission
- MeSH terms
- Animals, Haplorhini, Axons, Brain Diseases, Cerebral Cortex, Cytoplasm, Dendrites, Kuru, Microscopy, Electron, Nerve Degeneration, Neuroglia, Neurons
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