Cited by 873Cardiac Health and Mental HealthHeart Rate Variability and Autonomic ControlCardiovascular Health and Risk Factors

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Hostility, CHD Incidence, and Total Mortality: A 25-Year Follow-Up Study of 255 Physicians

Barefoot, John C., Dahlstrom, Grant W., Williams, Redford B.·1983·Psychosomatic Medicine

DOI 10.1097/00006842-198303000-00008

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Abstract

High levels of hostility as assessed by a MMPI scale (Ho) have been found associated with increased levels of arteriographically documented coronary atherosclerosis. In this study we examined the relationship between hostility and subsequent health status in a 25-year follow-up of 255 medical students who completed the MMPI while in medical school. High Ho scores were found to be predictive of both clinical coronary disease incidence and total mortality.

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“…and coronary artery disease Author, year N patients Follow-up (years) Scales Healthy subjects Shekelle et al., 1983 [44] 1877 10 MMPI, Ho, SS Barefoot et al., 1983 [45] 255 25 MMPI, Ho, SS McCranie et al., 1986 [47] 478 25 MMPI, Ho, SS Leon et al., 1988 [46] 280 30 MMPI, Ho, SS Barefoot et…”
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“25,26 Although there have been failures to replicate the prospective association between Ho scores and health outcomes, 27–29 a meta-analysis 30 concluded that the Ho scale is most predictive of all-cause mortality and, to a lesser extent, CHD (after controlling for other CHD risk factors) relative…”
What’s in a Name? Psychosomatic Medicine and Biobehavioral Medicine
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“") For the various complicated relations that arise, which for extralaboratory cases often render the analysis largely programmatic, see Skinner (1953, Chapters 9, 14, et passim) and Reynolds (1975). Where does this leave us in examining the relation between Murray”
Background
Anger, hostility, and hospitalizations in patients with heart failure.
Keith, F., Krantz, D. S., Chen, R., Harris, K. M., Ware, C. M., Lee, A. K., Bellini, P. G., & Gottlieb, S. S. (2017) · Health Psychology · doi:10.1037/hea0000519 · Cited by 30
“These findings are consistent with studies indicating that hostility is predictive of total mortality, and not just cardiovascular mortality (Barefoot et al., 1983, 1989; Wong et al., 2014).”
Cynical hostility relates to a lack of habituation of the cardiovascular response to repeated acute stress
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Authors: Barefoot, J. C., Dahlstrom, G. W., & Williams, R. B.
Affiliations: University of North Carolina at Chapel Hill (US)
ORCID: Williams, Redford B.
Venue: Psychosomatic Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1983-03
Volume: 45
Issue: 1
Pages: 59-63
ISSN: 0033-3174 (ISSN-L)
DOI: 10.1097/00006842-198303000-00008
OpenAlex: W2072085129
Cited by: 866
References: 0
Citations by year: 2026: 1 · 2025: 10 · 2024: 3 · 2023: 4 · 2022: 3 · 2020: 48 · 2019: 2 · 2018: 8 · 2017: 4 · 2016: 11 · 2015: 6 · 2014: 19 · 2013: 14 · 2012: 20
FWCI: 20.07
Type: journal article
Language: en
Open access: closed
Locations: Psychosomatic Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: hostility, coronary heart disease incidence, all-cause mortality, coronary artery disease, medical students, long-term follow-up, risk prediction
MeSH terms: Adult, Angina Pectoris, Coronary Disease, Follow-Up Studies, Hostility, Humans, Male, Middle Aged, MMPI, Myocardial Infarction, Personality, Physicians

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Hostility, CHD Incidence, and Total Mortality: A 25-Year Follow-Up Study of 255 Physicians

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