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An Open Pilot Study of Citalopram for Behavioral Disturbances of Dementia Plasma Levels and Real-Time Observations
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Pollock and colleagues demonstrated the utility of citalopram for agitation in dementia in a short-term, unmasked study and two randomized, masked follow-up studies, but these preliminary data require replication in a larger randomized, double-blind, placebo-controlled trial specific to an AD population.
“In a short-term, unmasked study and two randomized, masked follow-up studies, Pollock and colleagues demonstrated the utility of citalopram for agitation in dementia, but these preliminary data require replication in a larger randomized, double-blind, placebo-controlled trial specific to an AD population17–19.”
From Effect of Citalopram on Agitation in Alzheimer Disease: The CitAD Randomized Clinical Trial (2014) · cites this paper as [17]
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Effect of Citalopram on Agitation in Alzheimer Disease: The CitAD Randomized Clinical Trial
Porsteinsson, A. P., Drye, L. T., Pollock, B. G., Devanand, D. P., Frangakis, C., Ismail, Z., Marano, C., Meinert, C. L., Mintzer, J. E., Munro, C. A., et al. (2014) · JAMA · doi:10.1001/jama.2014.93 · Cited by 572
Self-citationBédard, A., Landreville, P., Voyer, P., Verreault, R., & Vézina, J. (2011) · Aging & Mental Health · doi:10.1080/13607863.2011.569480 · Cited by 43
Metadata
- Authors
- Pollock, B. G., Mulsant, B. H., Sweet, R., Burgio, L. D., Kirshner, M. A., Shuster, K., & Rosen, J.
- Venue
- The American Journal of Geriatric Psychiatry
- Publisher
- Elsevier BV
- Published
- 1997-12
- Volume
- 5
- Issue
- 1
- Pages
- 70-78
- ISSN
- 1064-7481 (ISSN-L)
- OpenAlex
- W2096866962
- Cited by
- 64
- References
- 1
- Citations by year
- 2022: 2 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Geriatric Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH 01040, R29MH055106, P30MH052247)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- citalopram, dementia, behavioral problems, plasma drug concentration, antidepressant tolerability, post-stroke depression
- MeSH terms
- Aged, Aged, 80 and over, Aggression, Alzheimer Disease, Biological Availability, Female, Humans, Male, Middle Aged, Pilot Projects, Psychomotor Agitation, Social Behavior Disorders, Social Environment, Verbal Behavior, Citalopram, Selective Serotonin Reuptake Inhibitors
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