Cited by 196Air Quality and Health ImpactsClimate Change and Health ImpactsIndoor Air Quality and Microbial Exposure

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The Lag Structure Between Particulate Air Pollution and Respiratory and Cardiovascular Deaths in 10 US Cities

Luís Ferreira Braga, Alfésio, Zanobetti, Antonella, Schwartz, Joel·2001·Journal of Occupational and Environmental Medicine

DOI 10.1097/00043764-200111000-00001

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Abstract

To assess differences in the lag structure pattern between particulate matter < 10 microns/100 microns in diameter (PM10) and cause-specific mortality, we performed a time-series analysis in 10 US cities using generalized additive Poisson regressions in each city; nonparametric smooth functions were used to control for long time trend, weather, and day of the week. The PM10 effect was estimated based on its daily mean, 2-day moving average, and the cumulative 7-day effect by means of an unconstrained distributed lag model. A 10-microgram/m3 increase in the 7-day mean of PM10 was associated with increases in deaths due to pneumonia (2.7%, 95% confidence interval [CI]: 1.5, 3.9), chronic obstructive pulmonary disease (1.7%, 95% CI: 0.1, 3.3), and all cardiovascular diseases (1.0%, 95% CI: 0.6, 1.4). A 10-microgram/m3 increase in the 2-day mean of PM10 was associated with a 0.7% (95% CI: 0.3, 1.1) increase in deaths from myocardial infarction. When the distributed lag was assessed, two different patterns could be observed: respiratory deaths were more affected by air pollution levels on the previous days, whereas cardiovascular deaths were more affected by same-day pollution. These results contribute to the overall efforts so far in understanding how exposure to air pollution promotes adverse health effects.

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Authors: Luís Ferreira Braga, A., Zanobetti, A., & Schwartz, J.
Affiliations: Harvard University (US)
Corresponding author: Schwartz, Joel
ORCID: Zanobetti, Antonella
Schwartz, Joel
Venue: Journal of Occupational and Environmental Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2001-11
Volume: 43
Issue: 11
Pages: 927-933
ISSN: 1076-2752 (ISSN-L)
DOI: 10.1097/00043764-200111000-00001
OpenAlex: W2072650322
Cited by: 196
References: 23
Citations by year: 2025: 4 · 2024: 1 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 6 · 2019: 14 · 2018: 6 · 2017: 4 · 2016: 6 · 2015: 11 · 2014: 9 · 2013: 16 · 2012: 9
FWCI: 4.20
Type: journal article
Language: en
Open access: closed
Locations: Journal of Occupational and Environmental Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Environmental Health Sciences (ES0002, P30ES000002)
Topics: Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Air Quality and Health Impacts
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Indoor Air Quality and Microbial Exposure
Keywords: particulate matter, PM10, air pollution, lag structure, respiratory mortality, cardiovascular mortality, pneumonia, chronic obstructive pulmonary disease, myocardial infarction, distributed lag models, urban air quality, air pollution health effects
MeSH terms: Air Pollutants, Cardiovascular Diseases, Environmental Monitoring, Humans, Particle Size, Regression Analysis, Respiratory Tract Diseases, Risk Factors, Time Factors, United States, Urban Population, Weather, Poisson Distribution, Statistics, Nonparametric, Epidemiological Monitoring

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The Lag Structure Between Particulate Air Pollution and Respiratory and Cardiovascular Deaths in 10 US Cities

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