CoChat
Sign Up
Cited by 154Substance Abuse Treatment and OutcomesAlcoholism and Thiamine DeficiencyAlcohol Consumption and Health Effects

The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.

Alcoholic Neurobiology: Changes In Dependence and Recovery

Crews, Fulton T., Buckley, Tracey, Dodd, Peter R., Ende, Gabriele, Foley, Nina, Harper, Clive, He, Jun, Innes, David, Loh, El-Wui, Pfefferbaum, Adolf, Zou, Jian, Sullivan, Edith V.·2005·Alcoholism: Clinical & Experimental Research
DOI 10.1097/01.alc.0000175013.50644.61
Open this paper in CoChat — free account

Abstract

This article presents the proceedings of a symposium held at the meeting of the International Society for Biomedical Research on Alcoholism (ISBRA) in Mannheim, Germany, in October, 2004. Chronic alcoholism follows a fluctuating course, which provides a naturalistic experiment in vulnerability, resilience, and recovery of human neural systems in response to presence, absence, and history of the neurotoxic effects of alcoholism. Alcohol dependence is a progressive chronic disease that is associated with changes in neuroanatomy, neurophysiology, neural gene expression, psychology, and behavior. Specifically, alcohol dependence is characterized by a neuropsychological profile of mild to moderate impairment in executive functions, visuospatial abilities, and postural stability, together with relative sparing of declarative memory, language skills, and primary motor and perceptual abilities. Recovery from alcoholism is associated with a partial reversal of CNS deficits that occur in alcoholism. The reversal of deficits during recovery from alcoholism indicates that brain structure is capable of repair and restructuring in response to insult in adulthood. Indirect support of this repair model derives from studies of selective neuropsychological processes, structural and functional neuroimaging studies, and preclinical studies on degeneration and regeneration during the development of alcohol dependence and recovery form dependence. Genetics and brain regional specificity contribute to unique changes in neuropsychology and neuroanatomy in alcoholism and recovery. This symposium includes state-of-the-art presentations on changes that occur during active alcoholism as well as those that may occur during recovery-abstinence from alcohol dependence. Included are human neuroimaging and neuropsychological assessments, changes in human brain gene expression, allelic combinations of genes associated with alcohol dependence and preclinical studies investigating mechanisms of alcohol induced neurotoxicity, and neuroprogenetor cell expansion during recovery from alcohol dependence.

Overview

Integrity signals

Registry

Crossref · 10.1097/01.alc.0000175013.50644.61

Cites

73 of 73 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 72 references

Research works printed but not linked: 20

  1. Bendszus M, 2001, AJNR Am J Neuroradiol, 22, 1926
  2. Bengochea O, 1990, Histol Histopathol, 5, 349
  3. 10.1097/00000374-200002000-00005 · DOI
  4. Dodd PR, 1994, Alcohol Alcohol Suppl, 2, 187
  5. Ende G, 2003, Proc Int Soc Magn Reson Med Toronto, 439
  6. Ende G, 2004, Proc Int Soc Magn Reson Med Kyoto, 1317
  7. Ende G, 2004, Proc Int Soc Magn Reson Med Kyoto, 291
  8. Ende G, 2004, Proc Int Soc Magn Reson Med Kyoto, 1486
  9. Gage FH, 1994, J N I H Res, 6, 53
  10. Malberg JE, 2004, J Psychiatry Neurosci, 29, 196
  11. Mdzinarishvili A, 2002, Soc Neurosci, 105, A9
  12. Mitsuyama H, 1998, Alcohol Clin Exp Res, 22, 815
  13. Nixon SJ, 1993, Alcohol Induced Brain Damage, NIAAA monograph, 213
  14. Oscar-Berman M, 2000, Review of NIAAA's Neuroscience and Behavioral Research Portfolio, 437
  15. Parsons OA, 1993, Alcohol-Induced Brain Damage (NIAAA Research Monograph No. 22, 173
  16. Radel M, 2001, Drug Metab Dispos, 29, 489
  17. 10.1111/j.1530-0277.2001.tb02299.x · DOI
  18. Spear L, 2000, Alcohol Res Health, 24, 115
  19. Sullivan EV, 2000, Review of NIAAA's Neuroscience and Behavioral Research Portfolio, NIAAA Research Monograph No. 34, 473
  20. 10.1037//0894-4105.14.2.178 · DOI

Cited by

Sorted by citations

Items 101–153 of 153

Related

See all

Metadata

Authors
Crews, F. T., Buckley, T., Dodd, P. R., Ende, G., Foley, N., Harper, C., He, J., Innes, D., Loh, E.-W., Pfefferbaum, A., Zou, J., & Sullivan, E. V.
Affiliations
University of North Carolina at Chapel Hill (US)
Corresponding author
Crews, Fulton T.
ORCID
Venue
Alcoholism: Clinical & Experimental Research
Publisher
Wiley
Published
2005-08
Volume
29
Issue
8
Pages
1504-1513
ISSN
0145-6008 (ISSN-L)
DOI
10.1097/01.alc.0000175013.50644.61
OpenAlex
W2072741198
Cited by
154
References
72
Citations by year
2026: 1 · 2025: 2 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 26 · 2019: 10 · 2018: 3 · 2017: 6 · 2016: 9 · 2015: 7 · 2014: 6 · 2013: 11 · 2012: 5
FWCI
6.93
Type
journal article
Language
en
Open access
closed
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 3683 d)
Locations
  • Alcoholism Clinical and Experimental Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Health and Medical Research Council
  • National Medical Research Council
  • National Institute on Alcohol Abuse and Alcoholism (AA 12404, AA-05965, AA011605, AA012725-04, R01AA012388, AA17203, AA12388, AA06069, R01AA012404)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Clinical Neurology › Alcoholism and Thiamine Deficiency
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
alcoholism, chronic alcoholism, alcohol recovery, alcohol neurotoxicity, neuroplasticity, neural repair, neuropsychological deficits, executive function, visuospatial ability, postural stability, brain gene expression, genetic susceptibility, neuroimaging, neural progenitor cells
MeSH terms
Adult, Ethanol, Alcoholic Intoxication, Alcoholism, Brain Mapping, DNA Repair, Gene Expression Regulation, Humans, Magnetic Resonance Imaging, Memory, Short-Term, Motivation, Nerve Degeneration, Nerve Regeneration, Neurons, Neuropsychological Tests, Orientation, Receptors, GABA-A, Substance Withdrawal Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review