Cited by 299Musculoskeletal pain and rehabilitationMyofascial pain diagnosis and treatmentTemporomandibular Joint Disorders

A Cochrane Review of Manipulation and Mobilization for Mechanical Neck Disorders

Gross, Anita R., Hoving, Jan L., Haines, Ted A., Goldsmith, Charles H., Kay, T, Aker, Peter, Bronfort, Gert·2004·Spine

Abstract

Study design and objectives Our systematic review of randomized trials assessed whether manipulation and mobilization relieve pain or improve function/disability, patient satisfaction, and global perceived effect in adults with mechanical neck disorders. Summary of background data Neck disorders are common, disabling, and costly. Methods Computerized bibliographic databases were searched up to March 2002. Two independent reviewers conducted study selection, data abstraction, and methodologic quality assessment. Relative risk and standardized mean differences were calculated. In the absence of heterogeneity, pooled effect measures were calculated using a random effects model. Results Of the 33 selected trials, 42% were high quality trials. Single or multiple (3-11) sessions of manipulation or mobilization showed no benefit in pain relief when assessed against placebo, control groups, or other treatments for acute/subacute/chronic mechanical neck disorders with or without headache. There was strong evidence of benefit favoring multimodal care (mobilization and/or manipulation plus exercise) over a waiting list control for pain reduction [pooled standardized mean differences -0.85 (95% CI: -1.20 to -0.50)], improvement in function [pooled SMD -0.57 (95% CI: -0.94 to -0.21)] and global perceived effect [standardized mean differences -2.73 (95% CI: -3.30 to -2.16)] for subacute/chronic mechanical neck disorders with or without headache. Conclusions Mobilization and/or manipulation…

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Crossref · 10.1097/01.brs.0000131218.35875.ed

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Authors
Gross, A. R., Hoving, J. L., Haines, T. A., Goldsmith, C. H., Kay, T., Aker, P., & Bronfort, G.
Affiliations
  • McMaster University (CA)
  • Monash University (AU)
  • Northwestern Health Sciences University (US)
  • University of Toronto (CA)
  • Canadian Memorial Chiropractic College (CA)
Corresponding author
  • Gross, Anita R.
  • Haines, Ted A.
  • Goldsmith, Charles H.
Venue
Spine
Published
2004-07
Volume
29
Issue
14
Pages
1541-1548
ISSN
0362-2436 (ISSN-L)
OpenAlex
W2016127346
Cited by
299
References
80
Citations by year
2026: 3 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 10 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 10 · 2017: 14 · 2016: 11 · 2015: 16 · 2014: 17 · 2013: 15 · 2012: 16
FWCI
2.15
Type
journal article
Language
en
Open access
closed
Locations
  • Spine (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion)
  • Pure Amsterdam UMC (submittedVersion)
Funders
National Center for Complementary and Integrative Health (U01AT000170, AT 00170-05)
Topics
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Myofascial pain diagnosis and treatment
  • Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
Keywords
spinal manipulation, spinal mobilization, neck pain, headache, exercise therapy, multimodal care, neck function, treatment effectiveness
MeSH terms
Adult, Aged, Combined Modality Therapy, Exercise Therapy, Female, Headache, Humans, Male, Middle Aged, Pain Measurement, Randomized Controlled Trials as Topic, Treatment Outcome, Patient Satisfaction, Evidence-Based Medicine, Neck Pain, Recovery of Function, Manipulation, Spinal, Physical Therapy Modalities, Manipulation, Chiropractic

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