Cited by 87Palliative Care and End-of-Life IssuesEthics in medical practiceEthics and Legal Issues in Pediatric Healthcare

Intensive care decision making in the seriously ill and elderly*

Lloyd, Christian B., Nietert, Paul J., Silvestri, Gerard A.·2004·Critical Care Medicine

Abstract

Objective To determine the influence of self-reported preadmission quality of life, hypothetical quality of life and mortality prognosis, and length and intensity of intensive care on decision making in the seriously ill and elderly. Design Prospective cohort study. Setting Medical university. Subjects Adult inpatients with chronic illness and an estimated 50% 6-month mortality along with patients > or =80 yrs old with an acute illness. Interventions Patients were presented with two scenarios: a) mechanical ventilation for 14 days; and 2) mechanical ventilation for 1 month with tracheostomy and feeding tube placement. A modified time trade-off was used to vary survival and quality of life over plausible ranges. Patients could consent to intensive care or choose care directed at comfort measures. Measurements and main results Fifty patients were interviewed. As projected intensive care unit mortality rate or postintensive care unit quality of life decreased, patients were less likely to consent to intensive care. Postintensive care quality of life was as important to patients as intensive care survival estimates. However, prehospitalization quality of life did not significantly influence decision making regarding life-extending treatment. When progressing from the acute intensive care scenario to chronic mechanical ventilation with associated interventions, patients demanded a significant increase in survival and quality of life. Neither race nor previous intensive care unit a…

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Crossref · 10.1097/01.ccm.0000115636.29294.2f

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  • The clinical importance of a 9-percentage point change is supported by a study of seriously ill patients whose potential willingness to receive prolonged mechanical ventilation declined substantially when prognosis worsened from 50% to 40%.

    “The clinical importance of a 9–percentage point change is supported by a study of seriously ill patients whose potential willingness to receive prolonged mechanical ventilation declined substantially when prognosis worsened from 50% to 40% (30).”

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Authors
Lloyd, C. B., Nietert, P. J., & Silvestri, G. A.
Affiliations
Medical University of South Carolina (US)
Venue
Critical Care Medicine
Published
2004-03
Volume
32
Issue
3
Pages
649-654
ISSN
0090-3493 (ISSN-L)
OpenAlex
W2035577909
Cited by
87
References
1
Citations by year
2025: 3 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 3 · 2015: 5 · 2014: 3 · 2013: 5 · 2012: 8
FWCI
5.16
Type
journal article
Language
en
Open access
closed
Locations
  • Critical Care Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
  • Health Sciences › Health Professions › General Health Professions › Ethics in medical practice
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Ethics and Legal Issues in Pediatric Healthcare
Keywords
end-of-life decisions, quality of life, mortality prediction, mechanical ventilation, elderly patients, seriously ill patients, time trade-off, tracheostomy, feeding tube, comfort care, patient preferences, chronic disease
MeSH terms
Adult, Age Factors, Aged, Aged, 80 and over, Attitude to Health, Critical Care, Decision Making, Female, Humans, Intubation, Intratracheal, Male, Middle Aged, Palliative Care, Prognosis, Prospective Studies, Quality of Life, Respiration, Artificial, Terminal Care, United States, Logistic Models

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