The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients*
Abstract
OBJECTIVE: Compared with standard medical therapy (SMT), noninvasive ventilation (NIV) does not reduce the need for reintubation in unselected patients who develop respiratory failure after extubation. The goal of this study was to assess whether early application of NIV, immediately after extubation, is effective in preventing postextubation respiratory failure in an at-risk population. DESIGN: Multiple-center, randomized controlled study. SETTING: Multiple hospitals. PATIENTS: Ninety-seven consecutive patients with similar baseline characteristics, requiring >48 hrs of mechanical ventilation and considered at risk of developing postextubation respiratory failure (i.e., patients who had hypercapnia, congestive heart failure, ineffective cough and excessive tracheobronchial secretions, more than one failure of a weaning trial, more than one comorbid condition, and upper airway obstruction). INTERVENTIONS: After a successful weaning trial, the patients were randomized to receive NIV for > or = 8 hrs a day in the first 48 hrs or SMT. Primary outcome was the need for reintubation according to standardized criteria. Secondary outcomes were intensive care unit and hospital mortality, as well as time spent in the intensive care unit and in hospital. MEASUREMENTS AND MAIN RESULTS: Compared with the SMT group, the NIV group had a lower rate of reintubation (four of 48 vs. 12 of 49; p = .027). The need for reintubation was associated with a higher risk of mortality (p < .01). The use of NIV resulted in a reduction of risk of intensive care unit mortality (-10%, p < .01), mediated by the reduction for the need of reintubation. CONCLUSIONS: NIV was more effective than SMT in preventing postextubation respiratory failure in a population considered at risk of developing this complication.
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Cites
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POCOCK, S. J. (1977) · Biometrika · doi:10.1093/biomet/64.2.191 · Cited by 1,831
A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation
Esteban, A., Frutos, F., Tobin, M. J., Alía, I., Solsona, J. F., Valverdu, V., Fernández, R., de la Cal, M. A., Benito, S., Tomás, R., et al. (1995) · New England Journal of Medicine · doi:10.1056/nejm199502093320601 · Cited by 1,549
Evidence-Based Guidelines for Weaning and Discontinuing Ventilatory Support
MacIntyre, N. R. (2001) · Chest · doi:10.1378/chest.120.6_suppl.375s · Cited by 1,240
Noninvasive Positive-Pressure Ventilation for Respiratory Failure after Extubation
Esteban, A., Frutos-Vivar, F., Ferguson, N. D., Arabi, Y., Apezteguía, C., González, M., Epstein, S. K., Hill, N. S., Nava, S., Soares, M.-A., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032736 · Cited by 894
Self-citationEffect of Failed Extubation on the Outcome of Mechanical Ventilation
Epstein, S. K., Ciubotaru, R. L., & Wong, J. B. (1997) · Chest · doi:10.1378/chest.112.1.186 · Cited by 892
MEHTA, S., & HILL, N. S. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.2.9906116 · Cited by 890
Extubation Outcome after Spontaneous Breathing Trials with T-Tube or Pressure Support Ventilation
ESTEBAN, A., ALÍA, I., GORDO, F., FERNÁNDEZ, R., SOLSONA, J. F., VALLVERDÚ, I., MACÍAS, S., ALLEGUE, J. M., BLANCO, J., CARRIEDO, D., et al. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.156.2.9610109 · Cited by 795
ESTEBAN, A., ALÍA, I., TOBIN, M. J., GIL, A., GORDO, F., VALLVERDÚ, I., BLANCH, L., BONET, A., VÁZQUEZ, A., de PABLO, R., et al. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.159.2.9803106 · Cited by 773
Re-intubation increases the risk of nosocomial pneumonia in patients needing mechanical ventilation.
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Cited by
Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure
Rochwerg, B., Brochard, L., Elliott, M. W., Hess, D., Hill, N. S., Nava, S., Navalesi, P., Antonelli, M., Brozek, J., Conti, G., et al. (2017) · European Respiratory Journal · doi:10.1183/13993003.02426-2016 · Cited by 1,668
Self-citationNon-invasive ventilation in acute respiratory failure
Nava, S., & Hill, N. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60496-7 · Cited by 1,011
Self-citationHernández, G., Vaquero, C., Colinas, L., Cuena, R., González, P., Canabal, A., Sanchez, S., Rodriguez, M. L., Villasclaras, A., & Fernández, R. (2016) · JAMA · doi:10.1001/jama.2016.14194 · Cited by 607
Ouellette, D. R., Patel, S., Girard, T. D., Morris, P. E., Schmidt, G. A., Truwit, J. D., Alhazzani, W., Burns, S. M., Epstein, S. K., Esteban, A., et al. (2017) · Chest · doi:10.1016/j.chest.2016.10.036 · Cited by 432
Diaphragm ultrasonography to estimate the work of breathing during non-invasive ventilation
Vivier, E., Mekontso Dessap, A., Dimassi, S., Vargas, F., Lyazidi, A., Thille, A. W., & Brochard, L. (2012) · Intensive Care Medicine · doi:10.1007/s00134-012-2547-7 · Cited by 406
Metadata
- Authors
- Nava, S., Gregoretti, C., Fanfulla, F., Squadrone, E., Grassi, M., Carlucci, A., Beltrame, F., & Navalesi, P.
- Venue
- Critical Care Medicine
- Published
- 2005-11
- Volume
- 33
- Issue
- 11
- Pages
- 2465-2470
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W2129853084
- Cited by
- 552
- References
- 36
- FWCI
- 17.26
- Type
- journal article
- Language
- en
- Open access
- closed
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- Nava, S., Gregoretti, C., Fanfulla, F., Squadrone, E., Grassi, M., Carlucci, A., Beltrame, F., & Navalesi, P. (2005). Noninvasive ventilation to prevent respiratory failure after extubation in high-risk patients*. Critical Care Medicine. https://doi.org/10.1097/01.ccm.0000186416.44752.72
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