The DOI matches its Crossref record; 22 of the 23 references it cites were found in a registry or an index.
TREATMENT OF ERECTILE DYSFUNCTION FOLLOWING THERAPY FOR CLINICALLY LOCALIZED PROSTATE CANCER: PATIENT REPORTED USE AND OUTCOMES FROM THE SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS PROSTATE CANCER OUTCOMES STUDY
Abstract
Purpose Erectile dysfunction (ED) persists for years following curative therapies for clinically localized prostate cancer. We report use and treatment outcomes in a 5-year interval in a population based cohort from the Surveillance, Epidemiology, and End Results Prostate Cancer Outcomes Study. Materials and methods A sample of 1,977 men with localized prostate cancer who received external beam radiation therapy or radical prostatectomy in 1994 to 1995 were surveyed for 5 outcome measures of ED treatment, namely treatment, perceived helpfulness, erectile sufficiency, sexual activity frequency and erection maintenance. Subjects were surveyed 6, 12, 24 and 60 months after prostate cancer diagnosis. Results Overall 50.5% of men ever used ED treatment. The use of ED treatments increased during the study course. Subject age, regular sexual partner and baseline sexual activity were factors positively associated with ED treatments. While it was used uncommonly (1.9%), a penile prosthesis was perceived as the most helpful ED treatment (helped a lot in 52% of respondents). Sildenafil helped a lot in 12% of respondents. Erectile fullness, erection maintenance and sexual activity frequency were modestly improved in men using ED treatment compared with those in men not using ED treatment. Conclusions Approximately half of the patients in this population based cohort of men used ED treatment during the 5 years following prostate cancer diagnosis. Men using ED treatments had modest improve…
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“and discontinuation rates are exceedingly high (50–61%) irrespective of treatment effectiveness.21, 22, 23, 24, 25, 26”
From Preliminary Development of a Mindfulness-Based Group Therapy to Expand Couples’ Sexual Intimacy after Prostate Cancer: A Mixed Methods Approach (2021) · cites this paper as [24]
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“Not only are rates of erectile dysfunction (ED) higher than estimates from more selected cohorts,(3,4,7) but medical treatments for ED after prostate cancer have had poor success rates and dismal adherence over time.(8-11) Men are far more likely to receive ED treatments after radical prostatectomy than after radiatio…”
Background
Metadata
- Authors
- STEPHENSON, R. A., MORI, M., HSIEH, Y.-C., BEER, T. M., STANFORD, J. L., GILLILAND, F. D., HOFFMAN, R. M., & POTOSKY, A. L.
- Affiliations
- University of Southern California (US)
- Venue
- Journal of Urology
- Published
- 2005-08
- Volume
- 174
- Issue
- 2
- Pages
- 646-650
- ISSN
- 0022-5347 (ISSN-L)
- 1527-3792
- OpenAlex
- W2031931231
- Cited by
- 117
- References
- 23
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 7 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 9 · 2013: 8 · 2012: 7
- FWCI
- 4.81
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Urology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01pc067010-004, n01pc067009-004, n01pc067000-000, n01pc067005-009, n01pc067007-017, n01pc067006-000)
- National Cancer Institute (N01-PC-67010, N01-PC-67006, N01 PC-67009, N01 PC67000, N01-PC-67007, N01 PC 67005)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
- Health Sciences › Medicine › Urology › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Urology › Urological Disorders and Treatments
- Keywords
- erectile dysfunction, localized prostate cancer, erectile dysfunction treatment, penile prosthesis, sildenafil, sexual function, radical prostatectomy, external beam radiotherapy, treatment utilization, sexual frequency
- MeSH terms
- Sildenafil Citrate, Aged, Humans, Erectile Dysfunction, Male, Middle Aged, Piperazines, Prostatectomy, Prostatic Neoplasms, Purines, Sulfones, 3',5'-Cyclic-GMP Phosphodiesterases, Cohort Studies, Multicenter Studies as Topic, SEER Program, Penile Implantation
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