Cited by 117Sexual function and dysfunction studiesProstate Cancer Diagnosis and TreatmentUrological Disorders and Treatments

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TREATMENT OF ERECTILE DYSFUNCTION FOLLOWING THERAPY FOR CLINICALLY LOCALIZED PROSTATE CANCER: PATIENT REPORTED USE AND OUTCOMES FROM THE SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS PROSTATE CANCER OUTCOMES STUDY

STEPHENSON, ROBERT A., MORI, MOTOMI, HSIEH, YI-CHING, BEER, TOMASZ M., STANFORD, JANET L., GILLILAND, FRANK D., HOFFMAN, RICHARD M., POTOSKY, ARNOLD L.·2005·Journal of Urology

DOI 10.1097/01.ju.0000165342.85300.14

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Abstract

Purpose Erectile dysfunction (ED) persists for years following curative therapies for clinically localized prostate cancer. We report use and treatment outcomes in a 5-year interval in a population based cohort from the Surveillance, Epidemiology, and End Results Prostate Cancer Outcomes Study. Materials and methods A sample of 1,977 men with localized prostate cancer who received external beam radiation therapy or radical prostatectomy in 1994 to 1995 were surveyed for 5 outcome measures of ED treatment, namely treatment, perceived helpfulness, erectile sufficiency, sexual activity frequency and erection maintenance. Subjects were surveyed 6, 12, 24 and 60 months after prostate cancer diagnosis. Results Overall 50.5% of men ever used ED treatment. The use of ED treatments increased during the study course. Subject age, regular sexual partner and baseline sexual activity were factors positively associated with ED treatments. While it was used uncommonly (1.9%), a penile prosthesis was perceived as the most helpful ED treatment (helped a lot in 52% of respondents). Sildenafil helped a lot in 12% of respondents. Erectile fullness, erection maintenance and sexual activity frequency were modestly improved in men using ED treatment compared with those in men not using ED treatment. Conclusions Approximately half of the patients in this population based cohort of men used ED treatment during the 5 years following prostate cancer diagnosis. Men using ED treatments had modest improve…

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Authors: STEPHENSON, R. A., MORI, M., HSIEH, Y.-C., BEER, T. M., STANFORD, J. L., GILLILAND, F. D., HOFFMAN, R. M., & POTOSKY, A. L.
Affiliations: University of Southern California (US)
ORCID: MORI, MOTOMI
BEER, TOMASZ M.
STANFORD, JANET L.
HOFFMAN, RICHARD M.
POTOSKY, ARNOLD L.
Venue: Journal of Urology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2005-08
Volume: 174
Issue: 2
Pages: 646-650
ISSN: 0022-5347 (ISSN-L)
1527-3792
DOI: 10.1097/01.ju.0000165342.85300.14
OpenAlex: W2031931231
Cited by: 117
References: 23
Citations by year: 2026: 1 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 3 · 2021: 5 · 2020: 7 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 9 · 2013: 8 · 2012: 7
FWCI: 4.81
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Journal of Urology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (n01pc067010-004, n01pc067009-004, n01pc067000-000, n01pc067005-009, n01pc067007-017, n01pc067006-000)
National Cancer Institute (N01-PC-67010, N01-PC-67006, N01 PC-67009, N01 PC67000, N01-PC-67007, N01 PC 67005)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Health Sciences › Medicine › Urology › Prostate Cancer Diagnosis and Treatment
Health Sciences › Medicine › Urology › Urological Disorders and Treatments
Keywords: erectile dysfunction, localized prostate cancer, erectile dysfunction treatment, penile prosthesis, sildenafil, sexual function, radical prostatectomy, external beam radiotherapy, treatment utilization, sexual frequency
MeSH terms: Sildenafil Citrate, Aged, Humans, Erectile Dysfunction, Male, Middle Aged, Piperazines, Prostatectomy, Prostatic Neoplasms, Purines, Sulfones, 3',5'-Cyclic-GMP Phosphodiesterases, Cohort Studies, Multicenter Studies as Topic, SEER Program, Penile Implantation

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TREATMENT OF ERECTILE DYSFUNCTION FOLLOWING THERAPY FOR CLINICALLY LOCALIZED PROSTATE CANCER: PATIENT REPORTED USE AND OUTCOMES FROM THE SURVEILLANCE, EPIDEMIOLOGY, AND END RESULTS PROSTATE CANCER OUTCOMES STUDY

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