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Chronic Pain and Psychopathology: Research Findings and Theoretical Considerations
Abstract
OBJECTIVE: Numerous studies have documented a strong association between chronic pain and psychopathology. Previous research has shown that chronic pain is most often associated with depressive disorders, anxiety disorders, somatoform disorders, substance use disorders, and personality disorders. The primary objective of this review article is to describe the nature of the relationship between chronic pain and each of these types of psychopathology. In addition, this article will explore how each of these disorders are expressed within the context of chronic pain, with a consideration of both diagnostic and treatment issues. METHODS: Medline and PsychLit searches of the chronic pain/psychopathology literature from 1980 through 2000 were conducted using the keywords chronic pain, psychopathology, psychiatric disorders, and psychological disorders. RESULTS: The relationship between chronic pain and psychopathology has generated substantial empirical and theoretical interest, with depressive disorders receiving much of the attention. CONCLUSIONS: Although no single theoretical model can fully explain the causal relationship between chronic pain and psychopathology, a diathesis-stress model is emerging as the dominant overarching theoretical perspective. In this model, diatheses are conceptualized as preexisting, semidormant characteristics of the individual before the onset of chronic pain that are then activated and exacerbated by the stress of this chronic condition, eventuall…
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“The diathesis-stress model is a theoretical perspective that explains the causal relationship between chronic pain and psychopathology (12).”
From Identifying mindfulness and acceptance as mediators between negative affect, functional disability and emotional distress in patients with fibromyalgia (2021) · cites this paper as [12]
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Metadata
- Authors
- Dersh, J., Polatin, P. B., & Gatchel, R. J.
- Affiliations
- Productive Rehabilitation Institute of Dallas for Ergonomics (US)
- ORCID
- Gatchel, Robert J.
- Venue
- Psychosomatic Medicine
- Published
- 2002-09
- Volume
- 64
- Issue
- 5
- Pages
- 773-786
- ISSN
- 0033-3174 (ISSN-L)
- OpenAlex
- W1991611223
- Cited by
- 676
- References
- 72
- Citations by year
- 2026: 5 · 2025: 15 · 2024: 17 · 2023: 30 · 2022: 26 · 2021: 21 · 2020: 68 · 2019: 21 · 2018: 25 · 2017: 31 · 2016: 28 · 2015: 42 · 2014: 39 · 2013: 34 · 2012: 37
- FWCI
- 7.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychosomatic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (2R01 MH46452, 2K02 MH 01107, K02MH001107, R01MH046452)
- National Institute of Dental and Craniofacial Research (R01DE010713, 2R01 DE10713)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- chronic pain, psychopathology, depressive disorders, anxiety disorders, somatoform disorders, substance use disorders, personality disorders, diathesis-stress model, pain management
- MeSH terms
- Anxiety, Chronic Disease, Major Depressive Disorder, Depressive Disorder, Major, Humans, MMPI, Pain, Personality Disorders, Personality Inventory, Psychiatric Status Rating Scales, Somatoform Disorders, Substance-Related Disorders
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- Dersh, J., Polatin, P. B., & Gatchel, R. J. (2002). Chronic Pain and Psychopathology: Research Findings and Theoretical Considerations. Psychosomatic Medicine. https://doi.org/10.1097/00006842-200209000-00010