Cited by 208Asthma and respiratory diseasesEstrogen and related hormone effectsEffects and risks of endocrine disrupting chemicals

The DOI matches its Crossref record; 58 of the 59 references it cites were found in a registry or an index.

Estrogen effects in allergy and asthma

Open access

Bonds, Rana S., Midoro-Horiuti, Terumi·2013·Current Opinion in Allergy & Clinical Immunology

DOI 10.1097/aci.0b013e32835a6dd6PMC PMC3537328

Open this paper in CoChat — free account

Abstract

PURPOSE OF REVIEW: Asthma prevalence and severity are greater in women than in men, and mounting evidence suggests this is in part related to female steroid sex hormones. Of these, estrogen has been the subject of much study. This review highlights recent research exploring the effects of estrogen in allergic disease. RECENT FINDINGS: Estrogen receptors are found on numerous immunoregulatory cells and estrogen's actions skew immune responses toward allergy. It may act directly to create deleterious effects in asthma, or indirectly via modulation of various pathways including secretory leukoprotease inhibitor, transient receptor potential vanilloid type 1 ion channel and nitric oxide production to exert effects on lung mechanics and inflammation. Not only do endogenous estrogens appear to play a role, but environmental estrogens have also been implicated. Environmental estrogens (xenoestrogens) including bisphenol A and phthalates enhance allergic sensitization in animal models and may enhance development of atopic disorders like asthma in humans. SUMMARY: Estrogen's role in allergic disease remains complex. As allergic diseases continue to increase in prevalence and affect women disproportionately, gaining a fuller understanding of its effects in these disorders will be essential. Of particular importance may be effects of xenoestrogens on allergic disease.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1097/aci.0b013e32835a6dd6

Cites

58 of 58 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Asthma prevalence, health care use, and mortality: United States, 2005-2009.
Akinbami, L. J., Moorman, J. E., & Liu, X. (2011) · PubMed · Cited by 951
Parent bisphenol A accumulation in the human maternal-fetal-placental unit.
Schönfelder, G., Wittfoht, W., Hopp, H., Talsness, C. E., Paul, M., & Chahoud, I. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.021100703 · Cited by 668
Impact of gender on asthma in childhood and adolescence: a GA 2 LEN review
Almqvist, C., Worm, M., Leynaert, B., & for the working group of GALEN WP 2.5 ‘Gender’ (2007) · Allergy · doi:10.1111/j.1398-9995.2007.01524.x · Cited by 563
The TLR-mediated response of plasmacytoid dendritic cells is positively regulated by estradiol in vivo through cell-intrinsic estrogen receptor α signaling
Seillet, C., Laffont, S., Trémollières, F., Rouquié, N., Ribot, C. A., Arnal, J., Douin‐Echinard, V., Gourdy, P., & Guéry, J. (2011) · Blood · doi:10.1182/blood-2011-08-371831 · Cited by 346
Gender differences in prevalence, diagnosis and incidence of allergic and non-allergic asthma: a population-based cohort
Leynaert, B., Sunyer, J., García‐Esteban, R., Svanes, C., Jarvis, D., Cerveri, I., Dratva, J., Gíslason, Þ., Heinrich, J., Janson, C., et al. (2012) · Thorax · doi:10.1136/thoraxjnl-2011-201249 · Cited by 268
Estradiol activates mast cells via a non-genomic estrogen receptor-α and calcium influx
Zaitsu, M., Narita, S.-I., Lambert, K. C., Grady, J. J., Estes, D. M., Curran, E. M., Brooks, E. G., Watson, C. S., Goldblum, R. M., & Midoro-Horiuti, T. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2006.09.030 · Cited by 262 · cited 3×
“ce partial release ts release induced [13,27] About 40% of women have perimenstrual worsening of their asthma symptoms”
BackgroundSelf-citation
Effective antigen presentation by dendritic cells is NF-κB dependent: coordinate regulation of MHC, co-stimulatory molecules and cytokines
Yoshimura, S., Bondeson, J., Foxwell, B. M. J., Brennan, F. M., & Feldmann, M. (2001) · International Immunology · doi:10.1093/intimm/13.5.675 · Cited by 241
Gender differences in asthma development and remission during transition through puberty: The TRacking Adolescents' Individual Lives Survey (TRAILS) study
Vink, N. M., Postma, D. S., Schouten, J. P., Rosmalen, J. G. M., & Boezen, H. M. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.06.018 · Cited by 228
Predicted risk of childhood allergy, asthma, and reported symptoms using measured phthalate exposure in dust and urine
Hsu, N., Lee, C., Wang, J., Li, Y.-C., Chang, H.-W., Chen, C., Bornehag, C., Wu, P., Sundell, J., & Su, H.-J. J. (2011) · Indoor Air · doi:10.1111/j.1600-0668.2011.00753.x · Cited by 207
The role of female hormones on lung function in chronic lung diseases
Tam, A., Morrish, D., Wadsworth, S. J., Dorscheid, D. R., Man, S. P., & Sin, D. D. (2011) · BMC Women s Health · doi:10.1186/1472-6874-11-24 · Cited by 205

Show all 59 references

Sorted by citations

New Look at BTEX: Are Ambient Levels a Problem?
Bolden, A. L., Kwiatkowski, C. F., & Colborn, T. (2015) · Environmental Science & Technology · doi:10.1021/es505316f · Cited by 458
Estrogen biology: New insights into GPER function and clinical opportunities
Prossnitz, E. R., & Barton, M. (2014) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2014.02.002 · Cited by 404
Androgens alter T-cell immunity by inhibiting T-helper 1 differentiation
Kissick, H. T., Sanda, M. G., Dunn, L. K., Pellegrini, K. L., On, S. T., Noel, J. K., & Arredouani, M. S. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1402468111 · Cited by 337
Estrogen accelerates the resolution of inflammation in macrophagic cells
Villa, A. M., Rizzi, N., Vegeto, E., Ciana, P., & Maggi, A. C. (2015) · Scientific Reports · doi:10.1038/srep15224 · Cited by 283
Prenatal exposure to bisphenol A and phthalates and childhood respiratory tract infections and allergy
Gascon, M., Casas, M., Morales, E., Valvi, D., Ballesteros-Gómez, A., Luque, N., Rubio, S., Monfort, N., Ventura, R., Martínez, D., et al. (2015) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.09.030 · Cited by 261
International Union of Basic and Clinical Pharmacology. XCVII. G Protein–Coupled Estrogen Receptor and Its Pharmacologic Modulators
Prossnitz, E. R., & Arterburn, J. B. (2015) · Pharmacological Reviews · doi:10.1124/pr.114.009712 · Cited by 269
Non‐IgE mediated mast cell activation
Redegeld, F. A., Yu, Y., Kumari, S., Charles, N., & Blank, U. (2018) · Immunological Reviews · doi:10.1111/imr.12629 · Cited by 215
Airway smooth muscle in airway reactivity and remodeling: what have we learned?
Prakash, Y. (2013) · American Journal of Physiology - Lung cellular and Molecular Physiology · doi:10.1152/ajplung.00259.2013 · Cited by 207
The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: a Review of Latest Findings
Robinson, L. B., & Miller, R. L. (2015) · Current Environmental Health Reports · doi:10.1007/s40572-015-0066-8 · Cited by 175
What have we learned about GPER function in physiology and disease from knockout mice
Prossnitz, E. R., & Hathaway, H. J. (2015) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2015.06.014 · Cited by 157
Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease
Prakash, Y. S. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00370.2016 · Cited by 136
Associations of prenatal environmental phenol and phthalate biomarkers with respiratory and allergic diseases among children aged 6 and 7 years
Buckley, J. P., Quirós-Alcalá, L., Teitelbaum, S. L., Calafat, A. M., Wolff, M. S., & Engel, S. M. (2018) · Environment International · doi:10.1016/j.envint.2018.03.016 · Cited by 123
Is there a sex-shift in prevalence of allergic rhinitis and comorbid asthma from childhood to adulthood? A meta-analysis
Fröhlich, M., Pinart, M., Keller, T., Reich, A., Cabieses, B., V, Hohmann, C., Postma, D. S., Bousquet, J., Anto, J. M., Keil, T. O. P., et al. (2017) · Clinical and Translational Allergy · doi:10.1186/s13601-017-0176-5 · Cited by 119
Associations of wheezing phenotypes with late asthma outcomes in the Avon Longitudinal Study of Parents and Children: A population-based birth cohort
Granell, R., Henderson, A. J., & Sterne, J. A. C. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.01.046 · Cited by 101
Phthalate-induced oxidative stress and association with asthma-related airway inflammation in adolescents
Franken, C., Lambrechts, N., Govarts, E., Koppen, G., Hond, E. D., Ooms, D., Voorspoels, S., Bruckers, L. M., Loots, I., Nelen, V., et al. (2017) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2017.01.006 · Cited by 92
Gender differences in murine pulmonary responses elicited by cellulose nanocrystals
Shvedova, A. A., Kisin, E. R., Yanamala, N. V. K., Farcas, M. T., Menas, A. L., Williams, A., Fournier, P. M., Reynolds, J. S., Gutkin, D. W., Star, A., et al. (2015) · Particle and Fibre Toxicology · doi:10.1186/s12989-016-0140-x · Cited by 87
Association of urinary levels of bisphenols F and S used as bisphenol A substitutes with asthma and hay fever outcomes
Mendy, A., Salo, P. M., Wilkerson, J., Feinstein, L., Ferguson, K. K., Fessler, M. B., Thorne, P. S., & Zeldin, D. C. (2019) · Environmental Research · doi:10.1016/j.envres.2019.108944 · Cited by 80
Associations between prenatal maternal urinary concentrations of personal care product chemical biomarkers and childhood respiratory and allergic outcomes in the CHAMACOS study
Berger, K. P., Eskenazi, B., Balmes, J. R., Holland, N., Calafat, A. M., & Harley, K. G. (2018) · Environment International · doi:10.1016/j.envint.2018.09.027 · Cited by 73
Prenatal exposure to bisphenol A and risk of allergic diseases in early life
Zhou, A., Chang, H., Huo, W., Zhang, B., Hu, J., Xia, W., Chen, Z., Xiong, C., Zhang, Y., Wang, Y., et al. (2017) · Pediatric Research · doi:10.1038/pr.2017.20 · Cited by 78
The Potential Roles of Bisphenol A (BPA) Pathogenesis in Autoimmunity
Kharrazian, D. (2014) · Autoimmune Diseases · doi:10.1155/2014/743616 · Cited by 72
G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis
Wei, T., Chen, W., Wen, L., Zhang, J., Zhang, Q., Yang, J., Liu, H., Chen, B. W., Zhou, Y., Feng, X., et al. (2016) · Cancer Letters · doi:10.1016/j.canlet.2016.08.012 · Cited by 70
Paraben exposures and asthma-related outcomes among children from the US general population
Quirós-Alcalá, L., Hansel, N. N., McCormack, M. C., & Matsui, E. C. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2018.08.021 · Cited by 68
An Inconvenient Variable: Sex Hormones and Their Impact on T Cell Responses
Brown, M. A., & Su, M. A. (2019) · The Journal of Immunology · doi:10.4049/jimmunol.1801403 · Cited by 74
The Natural History and Risk Factors for the Development of Food Allergies in Children and Adults
Lee, E. C. K., Trogen, B., Brady, K., Ford, L. S., & Wang, J. (2024) · Current Allergy and Asthma Reports · doi:10.1007/s11882-024-01131-3 · Cited by 75
Food allergy and atopic dermatitis: Prediction, progression, and prevention
Mastrorilli, C., Caffarelli, C., & Hoffmann‐Sommergruber, K. (2017) · Pediatric Allergy and Immunology · doi:10.1111/pai.12831 · Cited by 66
Bisphenol A exposure may increase the risk of development of atopic disorders in children
Wang, I., Chen, C., & Bornehag, C. (2015) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2015.12.001 · Cited by 65
Gender aspects and influence of hormones on bronchial asthma – Secondary publication and update
Koper, I., Hufnagl, K., & Ehmann, R. (2017) · World Allergy Organization Journal · doi:10.1186/s40413-017-0177-9 · Cited by 63
Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice
O’Brien, E., Dolinoy, D. C., & Mancuso, P. (2013) · Journal of Immunotoxicology · doi:10.3109/1547691x.2013.822036 · Cited by 62
Targeting mast cells: a new way to treat endometriosis
Binda, M. M., Donnez, J., & Dolmans, M. (2016) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1260548 · Cited by 59
Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation
Ambhore, N. S., Katragadda, R., Kalidhindi, R. S. R., Thompson, M. A., Pabelick, C. M., Prakash, Y. S., & Sathish, V. (2018) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2018.04.007 · Cited by 60
Gender difference in hepatic toxicity of titanium dioxide nanoparticles after subchronic oral exposure in Sprague‐Dawley rats
Chen, Z., Zhou, D., Zhou, S., & Jia, G. (2019) · Journal of Applied Toxicology · doi:10.1002/jat.3769 · Cited by 62
Role of Differential Estrogen Receptor Activation in Airway Hyperreactivity and Remodeling in a Murine Model of Asthma
Ambhore, N. S., Kalidhindi, R. S. R., Loganathan, J., & Sathish, V. (2019) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2018-0321oc · Cited by 59
Exposure to low-dose bisphenol A during the juvenile period of development disrupts the immune system and aggravates allergic airway inflammation in mice
Koike, E., Yanagisawa, R., Win‐Shwe, T., & Takano, H. (2018) · International Journal of Immunopathology and Pharmacology · doi:10.1177/2058738418774897 · Cited by 58
Exposure to bisphenols and asthma morbidity among low-income urban children with asthma
Quirós-Alcalá, L., Hansel, N. N., McCormack, M. C., Calafat, A. M., Ye, X., Peng, R. D., & Matsui, E. C. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.05.031 · Cited by 56
Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice
Kalidhindi, R. S. R., Ambhore, N. S., Bhallamudi, S., Loganathan, J., & Sathish, V. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01499 · Cited by 56
Gender-Related Effects of Sex Steroids on Histamine Release and Fc ε RI Expression in Rat Peritoneal Mast Cells
Muñoz-Cruz, S., Mendoza-Rodríguez, Y., Nava-Castro, K. E., Yepez-Mulia, L., & Morales-Montor, J. (2015) · Journal of Immunology Research · doi:10.1155/2015/351829 · Cited by 54
Exposure to bisphenol A and the development of asthma: A systematic review of cohort studies
Xie, M., Ni, H., Zhao, D., Wen, L., Li, K.-S., Yang, H., Wang, S., Zhang, H., & Su, H. (2016) · Reproductive Toxicology · doi:10.1016/j.reprotox.2016.08.007 · Cited by 54
Focus on mast cells in the tumor microenvironment: Current knowledge and future directions
Shi, S., Ye, L., Yu, X., Jin, K., & Wu, W. (2022) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2022.188845 · Cited by 53
Bisphenol A induced toxicity in blood cells of freshwater fish Channa punctatus after acute exposure
Sharma, P., & Chadha, P. (2021) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2021.04.088 · Cited by 49
Asthma prevalence among United States population insights from NHANES data analysis
Swed, S., Sawaf, B., Al-Obeidat, F. N., Hafez, W., Rakab, A., Alibrahim, H., Nasif, M. N., Alghalyini, B., Zaidi, A. R. Z., Alshareef, L., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-58429-5 · Cited by 48
Gender-specific determinants of asthma among U.S. adults
Greenblatt, R. E., Mansour, O., Zhao, E. J., Ross, M., & Himes, B. E. (2017) · Asthma Research and Practice · doi:10.1186/s40733-017-0030-5 · Cited by 47
Sex hormones and allergies: exploring the gender differences in immune responses
Gutiérrez-Brito, J. A., Lomelí-Nieto, J. Á., Muñóz-Valle, J. F., Oregon‐Romero, E., Corona-Angeles, J. A., & Hernández‐Bello, J. (2025) · Frontiers in Allergy · doi:10.3389/falgy.2024.1483919 · Cited by 44
Sex Differences in Airway Remodeling and Inflammation: Clinical and Biological Factors
Ekpruke, C. D., & Silveyra, P. (2022) · Frontiers in Allergy · doi:10.3389/falgy.2022.875295 · Cited by 50
In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts
Abellan, A., Mensink‐Bout, S. M., García‐Esteban, R., Beneíto, A., Chatzi, L., Duarte‐Salles, T., Fernández, M. F., García‐Aymerich, J., Granum, B. B., Íñiguez, C., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107178 · Cited by 40
Interaction effects of polyfluoroalkyl substances and sex steroid hormones on asthma among children
Zhou, Y., Hu, L., Qian, Z. M., Geiger, S. D., Parrish, K. L., Dharmage, S. C., Campbell, B., Roponen, M., Jalava, P., Hirvonen, M.-R., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-01140-5 · Cited by 40
Sex Differences in the Relationship between Asthma and Overweight in Dutch Children: a Survey Study
Willeboordse, M., van den Bersselaar, D. L. C. M., van de Kant, K. D. G., Muris, J. W. M., van Schayck, O. C. P., & Dompeling, E. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077574 · Cited by 40
Genome-wide analysis revealed sex-specific gene expression in asthmatics
Gautam, Y., Afanador, Y., Abebe, T., López, J. E., & Baye, T. M. (2019) · Human Molecular Genetics · doi:10.1093/hmg/ddz074 · Cited by 42
History of Allergy and Atopic Dermatitis in Relation to Squamous Cell and Basal Cell Carcinoma of the Skin
Cheng, J., Zens, M. S., Duell, E. J., Perry, A. E., Chapman, M. S., & Karagas, M. R. (2015) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-14-1243 · Cited by 39
Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States
Forno, E., Han, Y.-Y., Libman, I., Muzumdar, R., & Celedón, J. (2017) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201709-723oc · Cited by 33
Hormonal contraceptives and onset of asthma in reproductive-age women: Population-based cohort study
Nwaru, B. I., Pillinger, R., Tibble, H., Shah, S. A., Ryan, D. P., Critchley, H., Price, D. B., Hawrylowicz, C. M., Simpson, C. R., Soyiri, I. N., et al. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.02.027 · Cited by 37
Sex differences in airway disease: estrogen and airway surface liquid dynamics
Harvey, B. J., & McElvaney, N. G. (2024) · Biology of Sex Differences · doi:10.1186/s13293-024-00633-z · Cited by 39
Bisphenol A Exposure and Asthma Development in School-Age Children: A Longitudinal Study
Kim, K. N., Kim, J. H., Kwon, H., Hong, S., Kim, B., Lee, S. Y., Hong, Y., & Bae, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111383 · Cited by 37
Menopause, lung function and obstructive lung disease outcomes: a systematic review
Campbell, B., Davis, S. R., Abramson, M. J., Mishra, G. D., Handelsman, D. J., Perret, J. L., & Dharmage, S. C. (2017) · Climacteric · doi:10.1080/13697137.2017.1392504 · Cited by 37
Lung inflammation induced by exposure to Bisphenol-A is associated with mTOR-mediated autophagy in adolescent mice
Wang, S., Yang, Y., Luo, D., Wu, D., Liu, H., Li, M., Sun, Q., & Jia, L. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126035 · Cited by 39
Hormonal contraception and the risk of severe asthma exacerbation: 17-year population-based cohort study
Nwaru, B. I., Tibble, H., Shah, S. A., Pillinger, R., McLean, S., Ryan, D. P., Critchley, H., Price, D. B., Hawrylowicz, C. M., Simpson, C. R., et al. (2020) · Thorax · doi:10.1136/thoraxjnl-2020-215540 · Cited by 38
Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells, cytokines, and inflammatory factors involved in allergy
Fan, Z., Che, H., Yang, S., & Chen, C. (2019) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2019.03.001 · Cited by 35
Oestrogen amplifies pre‐existing atopy‐associated Th2 bias in an experimental asthma model
Lauzon‐Joset, J., Mincham, K. T., Abad, A., Short, B. P., Holt, P. G., Strickland, D. H., & Leffler, J. (2019) · Clinical & Experimental Allergy · doi:10.1111/cea.13544 · Cited by 35
Endocrine Disruptor Bisphenol A (BPA) Triggers Systemic Para-Inflammation and is Sufficient to Induce Airway Allergic Sensitization in Mice
Loffredo, L. F., Coden, M. E., & Berdnikovs, S. (2020) · Nutrients · doi:10.3390/nu12020343 · Cited by 35
Perinatal bisphenol A exposure beginning before gestation enhances allergen sensitization, but not pulmonary inflammation, in adult mice
O’Brien, E., Bergin, I. L., Dolinoy, D. C., Zasłona, Z., Little, R. J. A., Tao, Y., Peters-Golden, M. L., & Mancuso, P. (2014) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s204017441400004x · Cited by 33
Air Pollution and Weather Conditions Are Associated with Daily Outpatient Visits of Atopic Dermatitis in Shanghai, China
Ye, C., Gu, H., Li, M., Chen, R., Xiao, X., & Zou, Y. (2022) · Dermatology · doi:10.1159/000522491 · Cited by 32
Hormone Replacement Therapy and Risk of Severe Asthma Exacerbation in Perimenopausal and Postmenopausal Women: 17-Year National Cohort Study
Nwaru, B. I., Shah, S. A., Tibble, H., Pillinger, R., McLean, S., Ryan, D. P., Critchley, H., Hawrylowicz, C. M., Simpson, C. R., Soyiri, I. N., et al. (2021) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2021.02.052 · Cited by 34
Urinary levels of phthalate, bisphenol, and paraben and allergic outcomes in children: Korean National Environmental Health Survey 2015–2017
Hwang, M.-Y., Choi, K., & Park, C.-H. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.151703 · Cited by 32
Prenatal exposure to phthalates and peripheral blood and buccal epithelial DNA methylation in infants: An epigenome-wide association study
England-Mason, G., Merrill, S. M., Gladish, N., Moore, S. R., Giesbrecht, G. F., Letourneau, N. L., MacIsaac, J. L., MacDonald, A. M., Kinniburgh, D. W., Ponsonby, A., et al. (2022) · Environment International · doi:10.1016/j.envint.2022.107183 · Cited by 32
Urinary bisphenol A concentrations in relation to asthma in a sample of Egyptian children
Youssef, M., El-Din, E. M. S., AbuShady, M. M., Baroudy, N. R. E., el hamid, T. A., Armaneus, A., Refay, A. S. E., Hussein, J., Medhat, D., & Latif, Y. A. (2018) · Human & Experimental Toxicology · doi:10.1177/0960327118758150 · Cited by 32
Androgen Receptor-Mediated Regulation of Intracellular Calcium in Human Airway Smooth Muscle Cells
Kalidhindi, R. S. R., Katragadda, R., Beauchamp, K. L., Pabelick, C. M., Prakash, Y. S., & Sathish, V. (2019) · Cellular Physiology and Biochemistry · doi:10.33594/000000131 · Cited by 31
Sex—the most underappreciated variable in research: insights from helminth-infected hosts
Wesołowska, A. (2022) · Veterinary Research · doi:10.1186/s13567-022-01103-3 · Cited by 33
High risk of adult asthma following severe wheezing in early life
Goksör, E., Åmark, M., Alm, B., Ekerljung, L., Lundbäck, B., & Wennergren, G. (2014) · Pediatric Pulmonology · doi:10.1002/ppul.23071 · Cited by 30
Sex-Steroid Signaling in Lung Diseases and Inflammation
Ambhore, N. S., Kalidhindi, R. S. R., & Sathish, V. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-63046-1_14 · Cited by 30
Roads Less Traveled: Sexual Dimorphism and Mast Cell Contributions to Migraine Pathology
Loewendorf, A. I., Matynia, A., Saribekyan, H., Gross, N. B., CSETE, M. E., & Harrington, M. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00140 · Cited by 31
The Organophosphorus Pesticide Chlorpyrifos Induces Sex-Specific Airway Hyperreactivity in Adult Rats
Shaffo, F. C., Grodzki, A. C., Schelegle, E. S., & Lein, P. J. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy158 · Cited by 29
Gender differences in food allergy depend on the PPAR γ/NF-κB in the intestines of mice
Wang, J., Guo, X., Chen, C., Sun, S., Liu, G., Liu, M., Hao, M., & Che, H. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119606 · Cited by 29
Sex Steroids Effects on Asthma: A Network Perspective of Immune and Airway Cells
Borkar, N. A., Combs, C. K., & Sathish, V. (2022) · Cells · doi:10.3390/cells11142238 · Cited by 29
Leonurine attenuates OVA-induced asthma via p38 MAPK/NF-κB signaling pathway
Bai, D., Sun, Y., Li, Q., Li, H., Liang, Y., Xu, X., & Hao, J. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109483 · Cited by 30
T-cell–intrinsic Tif1α/Trim24 regulates IL-1R expression on T H 2 cells and T H 2 cell-mediated airway allergy
Perez-Lloret, J., Okoye, I., Guidi, R., Kannan, Y., Coomes, S. M., Czieso, S., Mengus, G., Davidson, I., & Wilson, M. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1522287113 · Cited by 28
Patterns of Carriage of Prescribed Adrenaline Autoinjectors in 10- to 14-Year-Old Food-Allergic Students: A Population-Based Study
Robinson, M. N., Koplin, J. J., Field, M. J., Sasaki, M., Peters, R. L., McWilliam, V. L., Sawyer, S. M., Patton, G. C., Vuillermin, P., Douglass, J. A., et al. (2018) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2018.06.025 · Cited by 28
Testosterone-to-estradiol ratio and lung function in a prospective study of Puerto Rican youth
Han, Y., Forno, E., Witchel, S. F., Manni, M. L., Acosta‐Pérez, E., CANINO, G. J., & Celedon, J. C. (2021) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2021.04.013 · Cited by 27
Longitudinal effects of prenatal exposure to plastic‐derived chemicals and their metabolites on asthma and lung function from childhood into adulthood
Foong, R. E., Franklin, P., Sanna, F., Hall, G. L., Sly, P. D., Thorstensen, E. B., Doherty, D. A., Keelan, J. A., & Hart, R. J. (2022) · Respirology · doi:10.1111/resp.14386 · Cited by 27
The Use of DAO as a Marker for Histamine Intolerance: Measurements and Determinants in a Large Random Population-Based Survey
van Odijk, J., Weisheit, A., Arvidsson, M., Miron, N., Nwaru, B. I., & Ekerljung, L. (2023) · Nutrients · doi:10.3390/nu15132887 · Cited by 27
Bisphenol A at concentrations relevant to human exposure enhances histamine and cysteinyl leukotriene release from bone marrow-derived mast cells
O’Brien, E., Dolinoy, D. C., & Mancuso, P. (2013) · Journal of Immunotoxicology · doi:10.3109/1547691x.2013.800925 · Cited by 27
Effects of Hormone Replacement Therapy on Women's Lung Health and Disease
Eliyahu, E., Katz, M. G., Vincek, A. S., Freage-Kahn, L., Ravvin, S., Tal, S., Grage, H., Shtraizent, N., Barak, T., & Arkush, B. (2023) · Pulmonary Therapy · doi:10.1007/s41030-023-00240-0 · Cited by 26
GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2
Xu, X., Wang, J., Guo, X., Chen, Y., Ding, S., Zou, G., Zhu, L., Li, T., & Zhang, X. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1106771 · Cited by 25
Estrogen Replacement Therapy and asthma
Ticconi, C., Pietropolli, A., & Piccione, E. (2013) · Pulmonary Pharmacology & Therapeutics · doi:10.1016/j.pupt.2013.08.004 · Cited by 25
Aryl hydrocarbon receptor deficiency enhanced airway inflammation and remodeling in a murine chronic asthma model
Chang, Y., Li, C.-H., Tsai, C.-H., Cheng, Y., Kang, J., & Lee, C. (2020) · The FASEB Journal · doi:10.1096/fj.202001529r · Cited by 24
Multimorbidity medications and poor asthma prognosis
Chanoine, S., Sanchez, M., Pin, I., Temam, S., Moual, N. L., Fournier, A., Pison, C. M., Bousquet, J., Bedouch, P., Boutron‐Ruault, M., et al. (2018) · European Respiratory Journal · doi:10.1183/13993003.02114-2017 · Cited by 23
Asthma, atopy, and exercise: Sex differences in exercise-induced bronchoconstriction
Bauza, D. E. R., & Silveyra, P. (2021) · Experimental Biology and Medicine · doi:10.1177/15353702211003858 · Cited by 22
Sex, hormones, and lung health
Silveyra, P., Babayev, M., & Ekpruke, C. D. (2025) · Physiological Reviews · doi:10.1152/physrev.00026.2024 · Cited by 22
Acute asthma in emergency department, prevalence of respiratory and non-respiratory symptoms
Refaat, S., & Aref, H. (2014) · Egyptian Journal of Chest Diseases and Tuberculosis · doi:10.1016/j.ejcdt.2014.07.013 · Cited by 19
Bisphenol A Activates an Innate Viral Immune Response Pathway
Sowers, M. L., Tang, H., Tian, B., Goldblum, R. M., Midoro‐Horiuti, T., & Zhang, K. (2019) · Journal of Proteome Research · doi:10.1021/acs.jproteome.9b00548 · Cited by 19
Self-citation
The Role of Airways 17β-Estradiol as a Biomarker of Severity in Postmenopausal Asthma: A Pilot Study
Scioscia, G., Carpagnano, G. E., Lacedonia, D., Soccio, P., Quarato, C. M. I., Trabace, L., Fuso, P., & Barbaro, M. P. F. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9072037 · Cited by 18
The Prevalence, Clinical Picture, and Triggers of Allergic Rhinitis in Saudi Population: A Systematic Review and Meta-Analysis
Aburiziza, A. J., Almatrafi, M. A., Alonazi, A. S., Zatari, M. H., Alqouzi, S. A., Mandili, R. A., Hawsawi, W. T., & Aljohani, R. H. (2022) · Journal of Asthma and Allergy · doi:10.2147/jaa.s391142 · Cited by 17
Understanding sex differences in the allergic immune response to food
Vininski, M. S., Rajput, S., Hobbs, N. J., & Dolence, J. J. (2022) · AIMS Allergy and Immunology · doi:10.3934/allergy.2022009 · Cited by 16
Drug repositioning by merging active subnetworks validated in cancer and COVID-19
Lucchetta, M., & Pellegrini, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-99399-2 · Cited by 15
Sex specific associations between in utero exposure to persistent organic pollutants and allergy-related outcomes in childhood: The Rhea Mother–Child Cohort (Crete, Greece)
Margetaki, K., Alexaki, M., Vittorakis, E., Roumeliotaki, T., Leventakou, V., Bempi, V., Chalkiadaki, G., Kyrtopoulos, S. A., Rantakokko, P., Kiviranta, H., et al. (2021) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174421000660 · Cited by 16
Prenatal exposure to replacement flame retardants and organophosphate esters and childhood adverse respiratory outcomes
Mendy, A., Percy, Z., Braun, J. M., Lanphear, B. P., Guardia, M. J. L., Hale, R. C., Yolton, K. A., & Chen, A. (2023) · Environmental Research · doi:10.1016/j.envres.2023.117523 · Cited by 16
Melia azedarach L. reduces pulmonary inflammation and mucus hypersecretion on a murine model of ovalbumin exposed asthma
Pak, S., Lee, I. S., Kim, W., Lee, S., Yang, Y.-G., Shin, I., & Kim, T. S. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.117426 · Cited by 16
Gender, Estrogen, and Obliterative Lesions in the Lung
Assaggaf, H. M., & Felty, Q. H. (2017) · International Journal of Endocrinology · doi:10.1155/2017/8475701 · Cited by 16
Inhaled Therapies for Asthma and Chronic Obstructive Pulmonary Disease
Liang, Y., & Mak, J. (2020) · Current Pharmaceutical Design · doi:10.2174/1389201021666201126144057 · Cited by 17
NF-κB—An Important Player in Xenoestrogen Signaling in Immune Cells
Nowak, K., Jabłońska, E., & Ratajczak–Wrona, W. (2021) · Cells · doi:10.3390/cells10071799 · Cited by 15
Life-long endogenous estrogen exposure is associated with prevalence of allergic rhinitis in postmenopausal women
Lee, K., Hong, Y., Choi, J., Lee, S. H., & Kim, T. H. (2019) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000001319 · Cited by 14
Role of G Protein-coupled Orphan Receptors in Intestinal Inflammation
Wasilewski, A., Storr, M., Zielińska, M., & Fichna, J. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000258 · Cited by 15

Authors: Bonds, R. S., & Midoro-Horiuti, T.
Affiliations: The University of Texas Medical Branch at Galveston (US)
Corresponding author: Bonds, Rana S.
Venue: Current Opinion in Allergy & Clinical Immunology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2013-02
Volume: 13
Issue: 1
Pages: 92-99
ISSN: 1473-6322 (ISSN-L)
1528-4050
DOI: 10.1097/aci.0b013e32835a6dd6
PMC: PMC3537328
OpenAlex: W1998158718
Cited by: 208
References: 59
Citations by year: 2026: 10 · 2025: 14 · 2024: 12 · 2023: 15 · 2022: 18 · 2021: 17 · 2020: 18 · 2019: 17 · 2018: 18 · 2017: 18 · 2016: 12 · 2015: 16 · 2014: 13 · 2013: 10
FWCI: 1.34
Type: journal article
Language: en
Open access: green
europepmc.org
Locations: Current Opinion in Allergy and Clinical Immunology (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (UL1TR000071)
National Institute of Environmental Health Sciences (R21ES016428, P30ES006676, ES016428)
National Center for Research Resources (UL1RR029876)
National Center for Advancing Translational Sciences
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Keywords: estrogen, asthma, allergy, sex hormones, estrogen receptor, immune regulation, secretory leukocyte protease inhibitor, TRPV1, nitric oxide, lung mechanics, lung inflammation, xenoestrogens, bisphenol A, phthalates, allergen sensitization, atopic diseases, sex differences
MeSH terms: Antigen-Presenting Cells, Asthma, Environmental Pollutants, Estrogens, Humans, Hypersensitivity, Mast Cells, Receptors, Estrogen, Cell Polarity, Immunoglobulin Class Switching, Th2 Cells

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Estrogen effects in allergy and asthma

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks