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The progression from acute to chronic pain
Abstract
PURPOSE OF REVIEW: The persistence of pain after surgical procedure or trauma has become a major focus of interest and its prevention now represents a challenge as an indicator of quality of healthcare. The only way to develop effective strategies to prevent the development of chronic pain is to better understand the mechanisms involved in the progression from acute to chronic pain, with the aim to target high-risk patients and to adapt perioperative management. RECENT FINDINGS: Several important risk factors involved in chronic pain development after tissue injury have been identified, underlining how much the phenomenon is complex and multifaceted. Recent studies have highlighted some important points on which to focus, mainly during the acute and subacute postinjury periods. These studies promote a more dynamic approach related to a better evaluation of acute pain resolution using individualized pain trajectories, the assessment of endogenous pain-modulatory processes and individual's psychological flexibility when facing physical threat and pain. SUMMARY: A dynamic view of both physiological and psychological response of an individual after injury (trauma, surgery) should improve our ability to target predisposed patients who might develop persistent pain. We should then be more able to provide those patients with the most appropriate preventive management.
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“Since numerous studies have demonstrated that depression, anxiety and other psychological co-morbidities (e.g. catastrophization, poor coping skills) are risk factors for pain chronification [7, 12, 18]”
From Telerehabilitation of acute musculoskeletal multi-disorders: prospective, single-arm, interventional study (2022) · cites this paper as [18]
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Metadata
- Authors
- Lavand’homme, P.
- Venue
- Current Opinion in Anaesthesiology
- Published
- 2011-10
- Volume
- 24
- Issue
- 5
- Pages
- 545-550
- ISSN
- 0952-7907 (ISSN-L)
- OpenAlex
- W1752227601
- Cited by
- 179
- References
- 46
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 12 · 2023: 13 · 2022: 8 · 2021: 11 · 2020: 9 · 2019: 13 · 2018: 11 · 2017: 10 · 2016: 20 · 2015: 18 · 2014: 16 · 2013: 15 · 2012: 12
- FWCI
- 2.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Anaesthesiology (publishedVersion)
- PubMed (publishedVersion)
- DIAL (Catholic University of Leuven) (submittedVersion)
- Topics
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- acute pain, chronic pain, postoperative pain, pain progression, risk factors, pain trajectories, endogenous pain modulation, psychological flexibility, perioperative care, pain prevention, tissue damage
- MeSH terms
- Acute Disease, Mental Disorders, Chronic Disease, Humans, Hyperalgesia, Neuralgia, Pain, Postoperative, Postoperative Pain, Disease Progression, Pain Management
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