CoChat
Sign Up
Cited by 191Pain Management and TreatmentPain Mechanisms and TreatmentsAnesthesia and Pain Management

The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.

The Natural History of Complex Regional Pain Syndrome

Schwartzman, Robert J., Erwin, Kirsten L., Alexander, Guillermo M.·2009·The Clinical Journal of Pain
DOI 10.1097/ajp.0b013e31818ecea5
Open this paper in CoChat — free account

Abstract

OBJECTIVE: Complex regional pain syndrome (CRPS) is a severe chronic pain condition characterized by sensory, autonomic, motor, and dystrophic signs and symptoms. This study was undertaken to expand our current knowledge of the evolution of CRPS signs and symptoms with duration of disease. METHOD: This was a retrospective, cross-sectional analysis using data extracted from a patient questionnaire to evaluate the clinical characteristics of CRPS at different time points of disease progression. Data from the questionnaire included pain characteristics and associated symptoms. It also included autonomic, motor, and dystrophic symptoms and also initiating events, ameliorating and aggravating factors, quality of life, work status, comorbid conditions, pattern of pain spread, family history, and demographics. Comparisons were made of different parameters as they varied with disease duration. RESULTS: A total of 656 patients with CRPS of at least 1-year duration were evaluated. The average age of all participants was 37.5 years, with disease duration varying from 1 to 46 years. The majority of participants were white (96%). A total of 80.3% were females. None of the patients in this study demonstrated spontaneous remission of their symptoms. The pain in these patients was refractory showing only modest improvement with most current therapies. DISCUSSION: This study shows that although CRPS is a progressive disease, after 1 year, the majority of the signs and symptoms were well developed and although many variables worsen over the course of the illness, the majority demonstrated only moderate increases with disease duration.

Overview

Integrity signals

Registry

Crossref · 10.1097/ajp.0b013e31818ecea5

Cites

62 of 62 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 61 references

Cited by

Sorted by citations

Items 101–189 of 189

Related

See all

Metadata

Authors
Schwartzman, R. J., Erwin, K. L., & Alexander, G. M.
Affiliations
Drexel University (US)
ORCID
Alexander, Guillermo M.
Venue
The Clinical Journal of Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2009-05
Volume
25
Issue
4
Pages
273-280
ISSN
0749-8047 (ISSN-L)
DOI
10.1097/ajp.0b013e31818ecea5
OpenAlex
W2011352969
Cited by
191
References
61
Citations by year
2026: 1 · 2025: 5 · 2024: 8 · 2023: 12 · 2022: 7 · 2021: 13 · 2020: 9 · 2019: 10 · 2018: 10 · 2017: 12 · 2016: 12 · 2015: 9 · 2014: 16 · 2013: 15 · 2012: 20
FWCI
19.83
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Anesthesia and Pain Management
Keywords
complex regional pain syndrome, disease progression, disease duration, chronic pain, autonomic symptoms, motor symptoms, refractory pain, quality of life, employment status, comorbidities, pain spread, family history (medicine)
MeSH terms
Adult, Female, Humans, Male, Pain Measurement, Pennsylvania, Cohort Studies, Prevalence, Disease Progression, Complex Regional Pain Syndromes

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review