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Practice Bulletin No. 157: Cervical Cancer Screening and Prevention
Abstract
The incidence of cervical cancer in the United States has decreased more than 50% in the past 30 years because of widespread screening. In 1975, the rate was 14.8 per 100,000 women. By 2011, it decreased to 6.7 per 100,000 women. Mortality from the disease has undergone a similar decrease from 5.55 per 100,000 women in 1975 to 2.3 per 100,000 women in 2011 (). The American Cancer Society (ACS) estimated that there would be 12,900 new cases of cervical cancer in the United States in 2015, with 4,100 deaths from the disease (). Cervical cancer is much more common worldwide, particularly in countries without screening programs, with an estimated 527,624 new cases of the disease and 265,672 resultant deaths each year (). When cervical cancer screening programs have been introduced into communities, marked reductions in cervical cancer incidence have followed ().New technologies for cervical cancer screening continue to evolve, as do recommendations for managing the results. In addition, there are different risk-benefit considerations for women at different ages, as reflected in age-specific screening recommendations. In 2011, the ACS, the American Society for Colposcopy and Cervical Pathology (ASCCP), and the American Society for Clinical Pathology (ASCP) updated their joint guidelines for cervical cancer screening (), as did the U.S. Preventive Services Task Force (USPSTF) (). Subsequently, in 2015, ASCCP and the Society of Gynecologic Oncology (SGO) issued interim guidance for the use of a human papillomavirus (HPV) test for primary screening for cervical cancer that was approved in 2014 by the U.S. Food and Drug Administration (FDA) (). The purpose of this document is to provide a review of the best available evidence regarding the prevention and early detection of cervical cancer.
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“Guidelines from USPSTF and ACOG recommend that cervical cancer screening begin at age 21 years (174,175).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [175]
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Metadata
- Venue
- Obstetrics & Gynecology
- Published
- 2016-01
- Volume
- 127
- Issue
- 1
- Pages
- e1-e20
- ISSN
- 0029-7844 (ISSN-L)
- OpenAlex
- W4254573998
- Cited by
- 118
- References
- 0
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 4 · 2023: 4 · 2022: 9 · 2021: 19 · 2020: 10 · 2019: 10 · 2018: 16 · 2017: 25 · 2016: 13
- FWCI
- 14.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Cervical Cancer and HPV Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Women's cancer prevention and management
- Health Sciences › Medicine › Obstetrics and Gynecology › Endometrial and Cervical Cancer Treatments
- Keywords
- cervical cancer, cervical cancer screening, HPV testing, primary HPV testing, colposcopy, cervical cancer incidence and mortality, cancer prevention, early detection
- MeSH terms
- Age Factors, Carcinoma in Situ, Uterine Cervical Neoplasms, Cytological Techniques, Female, Humans, Evidence-Based Medicine, Papillomavirus Infections, Papillomavirus Vaccines, Early Detection of Cancer
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