The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Depressive Disorders During Pregnancy: Prevalence and Risk Factors in a Large Urban Sample
Open accessAbstract
OBJECTIVE: To estimate the prevalence of major and minor depression, panic disorder, and suicidal ideation during pregnancy while also identifying factors independently associated with antenatal depressive disorders. METHODS: In this prospective study, participants were 1,888 women receiving ongoing prenatal care at a university obstetric clinic from January 2004 through January 2009. Prevalence of psychiatric disorders was measured using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria based on the Patient Health Questionnaire. Multiple logistic regression identified factors associated with probable major depressive disorder and any depressive disorder. RESULTS: Antenatal depressive disorders were present in 9.9% with 5.1% (97) meeting criteria for probable major depression and 4.8% (90) meeting criteria for probable minor depression. Panic disorder was present in 3.2% (61), and current suicidal ideation was reported by 2.6% (49). Among patients with probable major depression, 29.5% (28) reported current suicidal ideation. Psychosocial stress (odds ratio [OR], 1.29; 95% confidence interval [CI], 1.21-1.36), domestic violence (OR 3.45; 95% CI 1.46-8.12), chronic medical conditions (OR 3.05; 95% CI 1.63-5.69), and race (Asian: OR 5.81; 95% CI 2.55-13.23; or African American: OR 2.98; 95% CI 1.24-7.18) each significantly increased the odds of probable antepartum major depressive disorder, whereas older age (OR 0.92; 95% CI 0.88-0.97) decreased the odds. Factors associated with odds of any depression were similar overall except that Hispanic ethnicity (OR 2.50; 95% CI 1.09-5.72) also independently increased the odds of any depression. CONCLUSION: Antenatal major and minor depressive disorders are common and significantly associated with clinically relevant and identifiable risk factors. By understanding the high point prevalence and associated factors, clinicians can potentially improve the diagnosis and treatment rates of serious depressive disorders in pregnant women. LEVEL OF EVIDENCE: II.
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“Moreover, symptoms of depression and anxiety have been found to be exacerbated by higher levels of stress (13–15).”
From Acceptance, experiences, and needs of hospitalized pregnant women toward an electronic mindfulness-based intervention: A pilot mixed-methods study (2022) · cites this paper as [13]
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“” Suicidal ideation was assessed by an item on the Patient Health Questionnaire, which asks “Over the last 2 weeks how often have you been bothered by thoughts that you would be better off dead or of hurting yourself in some way?” and gives response options of “not at all” (0), “several days” (1), “more than half the…”
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Perinatal Depression: A Systematic Review of Prevalence and Incidence
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Comparison of two modes of stress measurement: Daily hassles and uplifts versus major life events
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Risk factors for depressive symptoms during pregnancy: a systematic review
Lancaster, C. A., Gold, K. J., Flynn, H. A., Yoo, H., Marcus, S. M., & Davis, M. M. (2010) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2009.09.007 · Cited by 1,208
Research works printed but not linked: 1
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Identifying the women at risk of antenatal anxiety and depression: a systematic review
Biaggi, A., Conroy, S., Pawlby, S., & Pariante, C. M. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.11.014 · Cited by 1,657
“…et al. (2009) Husain et al. (2011) Akcal et al. (2014) Srinivasan et al. (2015) Black/Latina/Asian ethnic group Faisal-Cury and Rossi Menezes (2007) Melville et al. (2010) Gavin et al. (2011) Redshaw and Henderson (2013) Fellenzer and Cibula (2014) Verreault et al. (2014) Shakeel et al.…”
BackgroundResultInfluentialVan den Bergh, B. R. H., van den Heuvel, M. I., Lahti, M., Braeken, M., de Rooij, S. R., Entringer, S., Hoyer, D., Roseboom, T., Räikkönen, K., King, S., et al. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.07.003 · Cited by 1,181
“For instance, in studies using clinical diagnostic tools, 8–12% of pregnant women meet criteria for a mental disorder during pregnancy, commonly an anxiety or mood disorder (Fisher et al., 2012; Howard et al., 2015; Melville et al., 2010).”
MethodGentile, S. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.001 · Cited by 431
“Pregnancy may increase the risk of depressive episodes, with more than 10% of women experiencing mood symptoms during the gestational period (Marcus et al., 2003; Melville et al., 2010).”
BackgroundResultPrevalence and associated factors of antenatal depression: Systematic reviews and meta-analyses
Yin, X., Sun, N., Jiang, N., Xu, X., Gan, Y., Zhang, J., Qiu, L., Yang, C., Shi, X., Chang, J., et al. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101932 · Cited by 409
Depression and treatment among U.S. pregnant and nonpregnant women of reproductive age, 2005–2009
Ko, J. Y., Farr, S. L., Dietz, P. M., & Robbins, C. L. (2012) · Journal of Women's Health · doi:10.1089/jwh.2011.3466 · Cited by 289
Metadata
- Authors
- Melville, J. L., Gavin, A., Guo, Y., Fan, M.-Y., & Katon, W. J.
- Affiliations
- University of Washington (US)
- Venue
- Obstetrics & Gynecology
- Published
- 2010-11
- Volume
- 116
- Issue
- 5
- Pages
- 1064-1070
- ISSN
- 0029-7844 (ISSN-L)
- PMC
- PMC3068619
- OpenAlex
- W1969021057
- Cited by
- 329
- References
- 49
- Citations by year
- 2026: 12 · 2025: 16 · 2024: 13 · 2023: 20 · 2022: 24 · 2021: 24 · 2020: 33 · 2019: 25 · 2018: 25 · 2017: 24 · 2016: 15 · 2015: 29 · 2014: 18 · 2013: 17 · 2012: 22
- FWCI
- 16.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- National Institutes of Health (1kl2rr025015-01)
- National Institute of Mental Health (K24MH069471, R01MH085668)
- National Center for Research Resources (KL2-RR025015, 1KL2-RR-025015-01)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R24HD042828)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy-related medical research
- Keywords
- antenatal depression, major depressive disorder, minor depression, panic disorder, suicidal ideation, pregnancy, prevalence, risk factors, psychosocial stress, domestic violence, chronic disease, ethnicity, Hispanic women, Asian women, African American women
- MeSH terms
- Adolescent, Adult, Depressive Disorder, Female, Humans, Middle Aged, Pregnancy, Pregnancy Complications, Risk Factors, Spouse Abuse, Stress, Psychological, Suicide, Urban Population, Prevalence, Panic Disorder, Young Adult
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