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Psychosocial factors and the pain experience of osteoarthritis patients: new findings and new directions
Abstract
PURPOSE OF REVIEW: The present paper reviews recent psychosocial research in the area of osteoarthritis pain. First, the review highlights studies of psychosocial factors that can influence osteoarthritis pain. Next, research testing the efficacy of psychosocial treatments for osteoarthritis pain is summarized. RECENT FINDINGS: Recent studies suggest that asking osteoarthritis patients to recall pain experiences may not be as accurate as having them keep daily pain records. New studies also support the notion that fatigue and increased weight are linked to higher osteoarthritis pain. Osteoarthritis patients who report higher levels of depression are more prone to report increased osteoarthritis pain. New studies also indicate that social factors such as ethnic background, ability to communicate pain to others, and participation in social activities can influence osteoarthritis pain and disability. Cognitions about pain (i.e. pain catastrophizing, acceptance, self-efficacy for pain) also have been found to relate to pain in patients with osteoarthritis. Recent, randomized controlled studies suggest that psychosocial interventions (i.e. self-management programs, exercise) can decrease osteoarthritis pain and disability. SUMMARY: Several psychosocial variables have been suggested as influencing osteoarthritis pain and disability. There is evidence that psychosocial interventions may decrease osteoarthritis pain and disability.
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“associations between catastrophizing and perceived solicitous responses 339, 340, 343, perceived instrumental support 103, and perceived critical responses to pain 106 have been observed.”
From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [343]
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“Studies also show that mental health may worsen when the quality of sleep is poor (Somers et al., 2009; Veldhuijzen et al., 2008).”
Hayashi, K., Morishima, T., Ikemoto, T., 宮川, 博., Okamoto, T., Ushida, T., & Deie, M. (2018) · Pain Medicine · doi:10.1093/pm/pny265 · Cited by 23
Tan, B. Y., Thach, T., Munro, Y. L., Skou, S. T., Thumboo, J., Car, J., & Car, L. T. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312757 · Cited by 22
“In addition, with the move away from the traditional biomedical model, which has been proven to be inadequate with poor concordance between pain, disability and pathology [9], towards a biopsychosocial model [10], there has been a greater recognition of the psychosocial factors in knee OA [11,12].”
BackgroundClinical effects of lateral wedge arch support insoles in knee osteoarthritis
Hsieh, R., & Lee, W. (2016) · Medicine · doi:10.1097/md.0000000000003952 · Cited by 20
Zhang, B., Yu, X. X., Liang, L., Zhu, L., Dong, X., Xiong, Y., Pan, Q., & Sun, Y. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/8654107 · Cited by 20
“For example, pain is influenced by a myriad of psychosocial factors that can vary between people as well as within people over time [52].”
BackgroundBaert, I. A. C., Nijs, J., Meeus, M., Lluch, E., & Struyf, F. (2014) · Clinical Rheumatology · doi:10.1007/s10067-014-2668-1 · Cited by 19
“, catastrophizing, high level of depression, cognition about pain) have been suggested as influencing OA pain and disability [75].”
BackgroundHu, Y., Su, Y., Chen, L., Zheng, G., Lin, X., Chen, B., Zhou, B., & Zhang, Q. (2013) · Trials · doi:10.1186/1745-6215-14-367 · Cited by 19
“Furthermore, dysfunction due to KOA strongly influences employment status, productivity [7,8] and increases obesity rates [9], especially among older people.”
BackgroundDinsdale, A., Forbes, R., Thomas, L. C., & Treleaven, J. M. (2021) · Musculoskeletal Science and Practice · doi:10.1016/j.msksp.2021.102401 · Cited by 15
Nian, X., He, Y., Ji, Y., Huang, Y., Sun, E., & Li, L. (2018) · Pain Medicine · doi:10.1093/pm/pny123 · Cited by 15
The Discordance Between Pain and Imaging in Knee Osteoarthritis
Hill, B. G., Eble, S. K., Moschetti, W. E., & Schilling, P. L. (2025) · Journal of the American Academy of Orthopaedic Surgeons · doi:10.5435/jaaos-d-24-00509 · Cited by 14
Varangot‐Reille, C., Barrero-Santiago, L., Cuenca‐Martínez, F., Paris‐Alemany, A., Touche, R. L., & Herranz‐Gómez, A. (2023) · Disability and Rehabilitation · doi:10.1080/09638288.2023.2252742 · Cited by 14
“…(pain catastrophizing, self-efficacy for pain, acceptance), psychological resources, ability to communicate pain to others and participation in social activities [11–13] Physical activity/inactivity are key elements for patients with OA due to its association with the physical function [14].”
Marks, R. (2013) · American journal of medicine studies · doi:10.12691/ajms-1-3-1 · Cited by 14
“Emerging data also reveal the disease process may be influenced adversely by a variety of psychological factors such as depression [13-19] and/or the self-efficacy beliefs held by the affected individual [20,21], both mutable factors.”
BackgroundThe burden of osteoarthritis:the societal and the patient perspective
Uhlig, T., Slatkowsky-Christensen, B., Moe, R. H., & Kvien, T. K. (2010) · Therapy · doi:10.2217/thy.10.70 · Cited by 13
Mannes, Z. L., Ferguson, E. G., Perlstein, W. M., Waxenberg, L. B., Cottler, L. B., & Ennis, N. (2020) · Health Psychology · doi:10.1037/hea0000847 · Cited by 17
“Furthermore, among patients with obesity and osteoarthritis, two conditions that have become a growing concern among retired NFL athletes, catastrophizing is correlated with poorer weight management, increased disability, and poorer weight related quality of life, all factors that can contribute to mood difficulties (…”
BackgroundTan, G., Dao, T., Smith, D., Robinson, A., & Jensen, M. (2010) · Psychological Services · doi:10.1037/a0020304 · Cited by 16
Hausmann, L. R. M., Ibrahim, S. A., Kwoh, C. K., Youk, A. O., Obrosky, D. S., Weiner, D. K., Vina, E. R., Gallagher, R. M., Mauro, G. T., & Parks, A. C. (2017) · Contemporary Clinical Trials · doi:10.1016/j.cct.2017.09.001 · Cited by 12
“Numerous studies have demonstrated that pain-related cognitions are associated with pain severity and functional impairment in patients with OA, with the most-oft studied and robust predictors being self-efficacy and pain catastrophizing.(26,55,61-64) Positive traits such as optimism and overall psychological resilien…”
Central sensitization in osteoarthritic knee pain: A cross-sectional study
Kılıçaslan, H. Ö., Genç, A., & Tuncer, S. (2022) · Turkish Journal of Physical Medicine and Rehabilitation · doi:10.5606/tftrd.2023.10470 · Cited by 12
“Psychosocial factors such as depression, pain catastrophizing, and sleep disturbances are known to be associated with pain experience in knee OA patients.[33] In our study, while both BDI and ISI scores were higher in the OA group than in the control group, this significance was found only in BDI in the RA group.”
BackgroundPérez, J. P., Mortensen, S. R., Girbés, E. L., Grønne, D. T., Thorlund, J. B., Roos, E. M., & Skou, S. T. (2024) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2024.2372381 · Cited by 12
“…anxiety, or pain-related fear of movement, have been suggested as negatively influencing KOA-related pain and disability (Baert et al., 2016; Somers, Keefe, Godiwala, and Hoyler, 2009) and may also be related to chronic postoperative pain in patients receiving total knee arthroplasty…”
Sources of pain in osteoarthritis: implications for therapy
Jones, G. (2013) · International Journal of Clinical Rheumatology · doi:10.2217/ijr.13.19 · Cited by 12
Bright, P., Hambly, K., & Tamakloe, S. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5374 · Cited by 12
Effects of exergames on rehabilitation outcomes in patients with osteoarthritis. A systematic review
Guede-Rojas, F., Andrades-Torres, B., Aedo-Díaz, N., González-Koppen, C., Muñoz-Fuentes, M., Enríquez-Enríquez, D., Carvajal-Parodi, C., Mendoza, C., Álvarez, C., & Fuentes, J. (2024) · Disability and Rehabilitation · doi:10.1080/09638288.2024.2368057 · Cited by 10
“Therefore, from a comprehensive therapeutic perspective, it should be considered that this set of signs and symptoms not only negatively influences physical functional capacity but also the cognitive [9] and psychosocial dimensions of OA patients [10].”
Body mass index, but not blood pressure is related to the level of pain in persons with chronic pain
Wood, D., Goodnight, S. M., Haig, A. J., & Nasari, T. J. (2011) · Journal of Back and Musculoskeletal Rehabilitation · doi:10.3233/bmr-2011-0284 · Cited by 10
“As Somers [19, 20] has pointed out, the relationships are much more complex.”
Psychosoziale Faktoren in der Prävention von Schmerz
Andrejeva, N., Baumeister, D., Eich, W., & Tesarz, J. (2021) · Der Schmerz · doi:10.1007/s00482-020-00523-4 · Cited by 9
Ram, A., Booth, J., Thom, J., & Jones, M. D. (2022) · Musculoskeletal Care · doi:10.1002/msc.1631 · Cited by 7
de Luca, K. E., Parkinson, L., Pollard, H. P., Byles, J., & Blyth, F. (2015) · Rheumatology International · doi:10.1007/s00296-015-3268-3 · Cited by 9
“Pain has multifaceted etiologies from within and outside of the joint [3, 4] and is influenced by psychosocial conditions [4, 5].”
BackgroundKnowledge expectations of recently diagnosed patients with knee osteoarthritis
Pellinen, T., Villberg, J. J., Raappana, M., Leino‐Kilpi, H., & Kettunen, T. (2016) · Journal of Advanced Nursing · doi:10.1111/jan.13053 · Cited by 8
Araya‐Quintanilla, F., & Cuyúl-Vásquez, I. (2018) · Revista de la Sociedad Española del Dolor · doi:10.20986/resed.2018.3679/2018 · Cited by 9
Imamura, M., Pacheco‐Barrios, K., de Melo, P. S., Marduy, A., Battistella, L. R., & Fregni, F. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14113633 · Cited by 7
Determining Brain Mechanisms that Underpin Analgesia Induced by the Use of Pain Coping Skills
Cole, L. J., Bennell, K. L., Ahamed, Y., Bryant, C., Keefe, F. J., Moseley, G. L., Hodges, P. W., & Farrell, M. J. (2017) · Pain Medicine · doi:10.1093/pm/pnx301 · Cited by 7
Self-citation
Metadata
- Authors
- Somers, T. J., Keefe, F. J., Godiwala, N., & Hoyler, G. H.
- Affiliations
- Duke Medical Center (US)
- Duke University (US)
- Corresponding author
- Keefe, Francis J
- Venue
- Current Opinion in Rheumatology
- Published
- 2009-09
- Volume
- 21
- Issue
- 5
- Pages
- 501-506
- ISSN
- 1040-8711 (ISSN-L)
- OpenAlex
- W1996735164
- Cited by
- 135
- References
- 57
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 6 · 2023: 2 · 2022: 5 · 2021: 10 · 2020: 7 · 2019: 3 · 2018: 13 · 2017: 11 · 2016: 9 · 2015: 9 · 2014: 12 · 2013: 12 · 2012: 10
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Rheumatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (P01-AR-50245, R01AR049059, P01AR050245, R01AR054626, R34AR056727)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Keywords
- osteoarthritis pain, psychosocial factors, pain catastrophizing, pain acceptance, depression, fatigue, body weight, pain recall, ethnicity, social participation (health and rehabilitation), pain communication, self-management program, exercise intervention, disability
- MeSH terms
- Cognition, Fatigue, Humans, Obesity, Osteoarthritis, Pain, Psychology, Stress, Psychological, Pain Management
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