The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
Surviving Sepsis Campaign: Association Between Performance Metrics and Outcomes in a 7.5-Year Study
Abstract
PURPOSE: To determine the association between compliance with the Surviving Sepsis Campaign (SSC) performance bundles and mortality. DESIGN: Compliance with the SSC performance bundles, which are based on the 2004 SSC guidelines, was measured in 29,470 subjects entered into the SSC database from January 1, 2005, through June 30, 2012. Compliance was defined as evidence that all bundle elements were achieved. SETTING: Two hundred eighteen community, academic, and tertiary care hospitals in the United States, South America, and Europe. PATIENTS: Patients from the emergency department, medical and surgical wards, and ICU who met diagnosis criteria for severe sepsis and septic shock. METHODS: A multifaceted, collaborative change intervention aimed at facilitating adoption of the SSC resuscitation and management bundles was introduced. Compliance with the SSC bundles and associated mortality rate was the primary outcome variable. RESULTS: Overall lower mortality was observed in high (29.0%) versus low (38.6%) resuscitation bundle compliance sites (p < 0.001) and between high (33.4%) and low (32.3%) management bundle compliance sites (p = 0.039). Hospital mortality rates dropped 0.7% per site for every three months (quarter) of participation (p < 0.001). Hospital and intensive care unit length of stay decreased 4% (95% CI: 1% - 7%; p = 0.012) for every 10% increase in site compliance with the resuscitation bundle. CONCLUSIONS: This analysis demonstrates that increased compliance with sepsis performance bundles was associated with a 25% relative risk reduction in mortality rate. Every 10% increase in compliance and additional quarter of participation in the SSC initiative was associated with a significant decrease in the odds ratio for hospital mortality. These results demonstrate that performance metrics can drive change in clinical behavior, improve quality of care, and may decrease mortality in patients with severe sepsis and septic shock.
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Cites
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock
Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827e83af · Cited by 9,694
Self-citationAngus, D. C., Linde-Zwirble, W. T., Lidicker, J., Clermont, G., Carcillo, J., & Pinsky, M. R. (2001) · Critical Care Medicine · doi:10.1097/00003246-200107000-00002 · Cited by 8,503
The Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup*, Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., et al. (2013) · Intensive Care Medicine · doi:10.1007/s00134-012-2769-8 · Cited by 7,290
Self-citationDellinger, R. P., Levy, M. M., Carlet, J. M., Bion, J., Parker, M. M., Jaeschke, R., Reinhart, K., Angus, D. C., Brun-Buisson, C., Beale, R., et al. (2008) · Intensive Care Medicine · doi:10.1007/s00134-007-0934-2 · Cited by 6,772
Self-citation2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
Levy, M. M., Fink, M. P., Marshall, J. C., Abraham, E., Angus, D., Cook, D., Cohen, J., Opal, S. M., Vincent, J.-L., & Ramsay, G. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000050454.01978.3b · Cited by 5,995
Self-citationSurviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
Dellinger, R. P., Carlet, J. M., Masur, H., Gerlach, H., Calandra, T., Cohen, J., Gea-Banacloche, J., Keh, D., Marshall, J. C., Parker, M. M., et al. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2210-z · Cited by 3,321
Self-citationA randomized trial of protocol-based care for early septic shock.
The ProCESS Investigators (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1401602 · Cited by 2,414
Regression Using Fractional Polynomials of Continuous Covariates: Parsimonious Parametric Modelling
Royston, P., & Altman, D. G. (1994) · Applied Statistics · doi:10.2307/2986270 · Cited by 1,798
Kaukonen, K.-M., Bailey, M., Suzuki, S., Pilcher, D., & Bellomo, R. (2014) · JAMA · doi:10.1001/jama.2014.2637 · Cited by 1,459
Benchmarking the Incidence and Mortality of Severe Sepsis in the United States*
Gaieski, D. F., Edwards, J. M., Kallan, M. J., & Carr, B. G. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827c09f8 · Cited by 1,326
Cited by
Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Intensive Care Medicine · doi:10.1007/s00134-017-4683-6 · Cited by 6,621
Self-citationSurviving Sepsis Campaign: International guidelines for management of sepsis and septic shock: 2016.
Rhodes, A., Evans, L. E., Alhazzani, W., Levy, M. M., Antonelli, M., Ferrer, R., Kumar, A., Sevransky, J. E., Sprung, C. L., Nunnally, M. E., et al. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002255 · Cited by 3,652
Self-citationTrial of early, goal-directed resuscitation for septic shock.
Mouncey, P. R., Osborn, T. M., Power, G. S., Harrison, D. A., Sadique, M. Z., Grieve, R. D., Jahan, R., Harvey, S. E., Bell, D., Bion, J. F., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1500896 · Cited by 1,604
Self-citationThe surviving sepsis campaign bundle: 2018 update
Levy, M. M., Evans, L. E., & Rhodes, A. (2018) · Intensive Care Medicine · doi:10.1007/s00134-018-5085-0 · Cited by 1,445
Self-citationThe timing of early antibiotics and hospital mortality in sepsis.
Liu, V. X., Fielding-Singh, V., Greene, J. D., Baker, J. M., Iwashyna, T. J., Bhattacharya, J., & Escobar, G. J. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201609-1848oc · Cited by 1,006
Metadata
- Authors
- Levy, M. M., Rhodes, A., Phillips, G. S., Townsend, S. R., Schorr, C. A., Beale, R., Osborn, T., Lemeshow, S., Chiche, J.-D., Artigas, A., & Dellinger, R. P.
- Venue
- Critical Care Medicine
- Published
- 2015-01
- Volume
- 43
- Issue
- 1
- Pages
- 3-12
- ISSN
- 0090-3493 (ISSN-L)
- OpenAlex
- W1969829944
- Cited by
- 566
- References
- 20
- FWCI
- 48.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- Levy, M. M., Rhodes, A., Phillips, G. S., Townsend, S. R., Schorr, C. A., Beale, R., Osborn, T., Lemeshow, S., Chiche, J.-D., Artigas, A., & Dellinger, R. P. (2015). Surviving Sepsis Campaign: Association Between Performance Metrics and Outcomes in a 7.5-Year Study. Critical Care Medicine. https://doi.org/10.1097/ccm.0000000000000723
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