The surviving sepsis campaign bundle: 2018 update
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A retrospective study revealed that identification and timely treatment of sepsis in the ED significantly reduced hospital mortality from 41% in untreated patients to 9% in treated patients.
“A retrospective study revealed that the identification and timely treatment of sepsis in the ED significantly reduced the hospital mortality rate, from 41% in untreated patients to 9% in treated patients.35”
From Development and validation of a screening tool for sepsis without laboratory results in the emergency department: a machine learning study (2025) · cites this paper as [35]
The Introduction (page unavailable) says early identification and immediate management of sepsis improve outcomes, and the Summary says sepsis bundles improve outcomes. Neither passage reports the claimed retrospective ED comparison or hospital mortality rates of 41% and 9%. (LLM, conf=0.86)
Experimental — accuracy not yet measuredEarly identification and timely treatment of sepsis significantly improve patient outcomes.
“Early identification and timely treatment of sepsis are known to significantly improve patient outcomes.35,36”
From Development and validation of a screening tool for sepsis without laboratory results in the emergency department: a machine learning study (2025) · cites this paper as [35]
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- Authors
- Levy, M. M., Evans, L. E., & Rhodes, A.
- Affiliations
- Brown University (US)
- New York University (US)
- St George's, University of London (GB)
- Corresponding author
- Levy, Mitchell M.
- Venue
- Intensive Care Medicine
- Published
- 2018-04-19
- Volume
- 44
- Issue
- 6
- Pages
- 925-928
- ISSN
- 0342-4642 (ISSN-L)
- 1432-1238
- OpenAlex
- W2801360758
- Cited by
- 1,445
- References
- 48
- Citations by year
- 2026: 62 · 2025: 94 · 2024: 119 · 2023: 168 · 2022: 174 · 2021: 317 · 2020: 269 · 2019: 190 · 2018: 49 · 2017: 2
- FWCI
- 161.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Intensive Care Medicine (publishedVersion)
- PubMed (publishedVersion)
- St George's Online Research Archive (St George's University of London) (acceptedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Abdominal Surgery and Complications
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Keywords
- sepsis, sepsis bundle, Surviving Sepsis Campaign, septic shock, sepsis management guidelines, quality improvement
- MeSH terms
- Humans, Shock, Septic, Practice Guidelines as Topic, Sepsis, Guideline Adherence
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